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International Journal of Nanomedicine Volume 15, 2020 - Issue
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Original Research

p66shc siRNA Nanoparticles Ameliorate Chondrocytic Mitochondrial Dysfunction in Osteoarthritis

Hyo Jung Shin1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea
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Hyewon Park1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea
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Nara Shin1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-3122-9417
ORCID Icon,
Juhee Shin1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-8236-9551
ORCID Icon,
Do Hyeong Gwon1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea
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Hyeok Hee Kwon1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;3 Department of PediatricsORCID Iconhttps://orcid.org/0000-0002-5850-8347
ORCID Icon,
Yuhua Yin1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-9212-5585
ORCID Icon,
Jeong-Ah Hwang1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea
,
Jinpyo Hong2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-4776-4396
ORCID Icon,
Jun Young Heo1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;4 Biochemistry;5 Infection Control Convergence Research CenterORCID Iconhttps://orcid.org/0000-0002-0859-0063
ORCID Icon,
Cuk-Seong Kim1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;6 Physiology Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Yongbum Joo7 Department of Orthopedics, Chungnam National University College of Medicine, Daejeon, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-4130-7431
ORCID Icon,
Youngmo Kim7 Department of Orthopedics, Chungnam National University College of Medicine, Daejeon, Republic of Korea
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Jinhyun Kim8 Division of Rheumatology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5235-2612
ORCID Icon,
Jaewon Beom9 Department of Rehabilitation Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Republic of Korea
&
Dong Woon Kim1 Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea;2 Department of Anatomy and Cell Biology, Brain Research Institute, Chungnam National University College of Medicine, Daejeon 35015, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7691-1394
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Pages 2379-2390 | Published online: 08 Apr 2020

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Mohammad-Amin Rahmati, Hamid Rashidzadeh, Mir-Jamal Hosseini, Somayeh Sadighian & Mehraneh Kermanian. (2022) Self-assembled magnetic polymeric micelles for delivery of quercetin: Toxicity evaluation on isolated rat liver mitochondria. Journal of Biomaterials Science, Polymer Edition 33:3, pages 279-298.
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Gundula Schulze-Tanzil. (2021) Experimental Therapeutics for the Treatment of Osteoarthritis. Journal of Experimental Pharmacology 13, pages 101-125.
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Dan Wu, Xi Li, Jun Liu, Can Hu & Jiefang Li. (2021) Wutou decoction attenuates rheumatoid arthritis by modulating the Ahr/LOC101928120/SHC1 pathway. Pharmaceutical Biology 59:1, pages 809-820.
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Yue Yu, Zhou Wang, Qinyan Yang, Qian Ding, Ran Wang, Zhaoyi Li, Yudong Fang, Junyi Liao, Wei Qi, Keyuan Chen, Meng Li & Yi Zhun Zhu. (2021) A novel dendritic mesoporous silica based sustained hydrogen sulfide donor for the alleviation of adjuvant-induced inflammation in rats. Drug Delivery 28:1, pages 1031-1042.
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Articles from other publishers (12)

Yue Shen, Li Teng, Yuhan Qu, Yuehui Huang, Yi Peng, Min Tang & Qiang Fu. (2022) Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study. Inflammation 46:2, pages 655-678.
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Adriano P. Pontes, Tim J. M. Welting, Jaap Rip & Laura B. Creemers. (2022) Polymeric Nanoparticles for Drug Delivery in Osteoarthritis. Pharmaceutics 14:12, pages 2639.
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Ramin Goudarzi, Ahmad Reza Dehpour & Alireza Partoazar. (2022) Nanomedicine and regenerative medicine approaches in osteoarthritis therapy. Aging Clinical and Experimental Research 34:10, pages 2305-2315.
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Yangfei Yi, Ningyin Yang, Qian Luo, Xiaojun Tao & Yufei Li. (2022) Delivery of Chondrocyte-Targeting sh-TTTY15 (Testis-Specific Transcript, Y-Linked 15) Nanoparticles Against LncRNA TTTY15 Improves Osteoarthritis by Regulating Autophagy and Oxidative Stress. Journal of Biomedical Nanotechnology 18:5, pages 1386-1396.
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Jian Wang, Liaoran Zhang, Jiaxue Zhu, Jianhua Gu, Xiang Wang & Hairong Tao. (2022) Hyaluronic Acid Modified Curcumin-Loaded Chitosan Nanoparticles Inhibit Chondrocyte Apoptosis to Attenuate Osteoarthritis via Upregulation of Activator Protein 1 and RUNX Family Transcription Factor 2. Journal of Biomedical Nanotechnology 18:1, pages 144-157.
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Keda Liu, Dianjian Zhang & Wei Wang. (2021) Nanoparticle-Based Drug Delivery System—A Target Strategy for Osteoarthritis Treatment. Journal of Nanomaterials 2021, pages 1-15.
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Ayesha Younas, Hongzhou Gu, Yongxing Zhao & Nan Zhang. (2021) Novel approaches of the nanotechnology-based drug delivery systems for knee joint injuries: A review. International Journal of Pharmaceutics 608, pages 121051.
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Xueli Mei, Ian J Villamagna, Tony Nguyen, Frank Beier, C Thomas Appleton & Elizabeth R Gillies. (2021) Polymer particles for the intra-articular delivery of drugs to treat osteoarthritis. Biomedical Materials 16:4, pages 042006.
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Shikhar Mehta, Tengfei He & Ambika G. Bajpayee. (2021) Recent advances in targeted drug delivery for treatment of osteoarthritis. Current Opinion in Rheumatology 33:1, pages 94-109.
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Jiawei Pei, Qian Huang, Mili Ji, Xiaohua Chu, Ye Tian, Airong Qian & Peihong Su. 2021. Noncoding RNAs and Bone. Noncoding RNAs and Bone 159 184 .
Guang-Zhen Jin. (2020) Current Nanoparticle-Based Technologies for Osteoarthritis Therapy. Nanomaterials 10:12, pages 2368.
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Thuỳ Linh Phạm & Dong Woon Kim. (2020) Poly(lactic-co-glycolic acid) nanomaterial-based treatment options for pain management: a review. Nanomedicine 15:19, pages 1897-1913.
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