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Original Research

Formulation and delivery of itraconazole to the brain using a nanolipid carrier system

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Pages 2117-2126 | Published online: 02 May 2014

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Yanming Wang, Zhang Chenghao, Zhaoli Wu, Xinran Cui, Jinmei Ren & Jingling Tang. (2023) In vivo and in vitro evaluation of pulmonary administration of itraconazole nanostructured lipid carriers for pulmonary aspergillosis. Drug Development and Industrial Pharmacy 49:2, pages 232-239.
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Shida Li, Wenxiu Wei, Weiping Jia, Lechen Zhao, Hongmei Xu, Feilong Zhou, Li Zhu, Zhimei Song, Sijia Feng & Runliang Feng. (2018) Itraconazole-loaded micelles based on linear-dendritic poly (ethylene glycol)-b-poly (ε-caprolactone). Journal of Biomaterials Science, Polymer Edition 29:18, pages 2299-2311.
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Katharine E Stott & William Hope. (2018) Pharmacokinetics–pharmacodynamics of antifungal agents in the central nervous system. Expert Opinion on Drug Metabolism & Toxicology 14:8, pages 803-815.
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Mona Mahmoud AbouSamra & Alaa Hamed Salama. (2017) Enhancement of the topical tolnaftate delivery for the treatment of tinea pedis via provesicular gel systems. Journal of Liposome Research 27:4, pages 324-334.
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Aline Raquel Voltan, Guillermo Quindós, Kaila P Medina Alarcón, Ana Marisa Fusco-Almeida, Maria José Soares Mendes-Giannini & Marlus Chorilli. (2016) Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?. International Journal of Nanomedicine 11, pages 3715-3730.
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Jun Zhou & Daxin Zhou. (2015) Improvement of oral bioavailability of lovastatin by using nanostructured lipid carriers. Drug Design, Development and Therapy 9, pages 5269-5275.
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Nikhil R. Bali & Pramod S. Salve. (2019) Selegiline nanoparticle embedded transdermal film: An alternative approach for brain targeting in Parkinson's disease. Journal of Drug Delivery Science and Technology 54, pages 101299.
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Chandrakantsing V. Pardeshi & Veena S. Belgamwar. (2018) N,N,N‑trimethyl chitosan modified flaxseed oil based mucoadhesive neuronanoemulsions for direct nose to brain drug delivery. International Journal of Biological Macromolecules 120, pages 2560-2571.
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