104
Views
50
CrossRef citations to date
0
Altmetric
Original Research

Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration

, , , , , , , & show all
Pages 5591-5601 | Published online: 01 Dec 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Dong-Hyun Kim, Thu Nhan Nguyen, Young-Min Han, Phuong Tran, Jinhyung Rho, Jae-Young Lee, Hwa-Young Son & Jeong-Sook Park. (2021) Local drug delivery using poly(lactic-co-glycolic acid) nanoparticles in thermosensitive gels for inner ear disease treatment. Drug Delivery 28:1, pages 2268-2277.
Read now
Hai Liu, Jianqiong Yang, Wanqing Yang, Shaonan Hu, Yali Wu, Bo Zhao, Haiyan Hu & Shouying Du. (2020) Focus on Notoginsenoside R1 in Metabolism and Prevention Against Human Diseases. Drug Design, Development and Therapy 14, pages 551-565.
Read now
Liping Zhang, Yuan Xu, Wenjuan Cao, Shibao Xie, Lu Wen & Gang Chen. (2018) Understanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine. International Journal of Nanomedicine 13, pages 479-492.
Read now
Xu Liu, Mingshuang Li, Hugh Smyth & Feng Zhang. (2018) Otic drug delivery systems: formulation principles and recent developments. Drug Development and Industrial Pharmacy 44:9, pages 1395-1408.
Read now
Juan Dai, Wei Long, Zhongping Liang, Lu Wen, Fan Yang & Gang Chen. (2018) A novel vehicle for local protein delivery to the inner ear: injectable and biodegradable thermosensitive hydrogel loaded with PLGA nanoparticles. Drug Development and Industrial Pharmacy 44:1, pages 89-98.
Read now
Xingxing Wen, Shan Ding, Hui Cai, Junyi Wang, Lu Wen, Fan Yang & Gang Chen. (2016) Nanomedicine strategy for optimizing delivery to outer hair cells by surface-modified poly(lactic/glycolic acid) nanoparticles with hydrophilic molecules. International Journal of Nanomedicine 11, pages 5959-5969.
Read now
Yue Zhang, Huanpeng Su, Lu Wen, Fan Yang & Gang Chen. (2016) Mathematical modeling for local trans-round window membrane drug transport in the inner ear. Drug Delivery 23:8, pages 3082-3087.
Read now
Rebekah Watkins, Ling Wu, Chenming Zhang, Richey M Davis & Bin Xu. (2015) Natural product-based nanomedicine: recent advances and issues. International Journal of Nanomedicine 10, pages 6055-6074.
Read now
Wei Wang, Mei Xi, Xuezhong Duan, Yong Wang & Fansheng Kong. (2015) Delivery of baicalein and paclitaxel using self-assembled nanoparticles: synergistic antitumor effect in vitro and in vivo. International Journal of Nanomedicine 10, pages 3737-3750.
Read now

Articles from other publishers (41)

Peng-Wei Ma, Pei-Heng Lu, Hao Yuan, Jia-Wei Chen, Wei Gao, Yu-Qiang Lun, Jia-Ning Guo, Xue-Rui Ding, Rui Liang, Si-Yu Li, Zi Wang, Wei-Long Wang & Lian-Jun Lu. (2023) Ferrostatin-1-loaded thermosensitive nanodelivery system for noise-induced hearing loss treatment. Chemical Engineering Journal 476, pages 146584.
Crossref
Wenbin Xiao, Kerui He, Chong Yu, Zeming Zhou, Liye Xia, Shibao Xie, Hanqi Li, Ming Zhang, Zhifeng Zhang, Pei Luo, Lu Wen & Gang Chen. (2023) Space Station-like Composite Nanoparticles for Co-Delivery of Multiple Natural Compounds from Chinese Medicine and Hydrogen in Combating Sensorineural Hearing Loss. Molecular Pharmaceutics 20:8, pages 3987-4006.
Crossref
Xinrui Wang, Zeming Zhou, Chong Yu, Kerui He, Lifang Sun, Yuwei Kou, Ming Zhang, Zhifeng Zhang, Pei Luo, Lu Wen & Gang Chen. (2023) A prestin-targeting peptide-guided drug delivery system rearranging concentration gradient in the inner ear: An improved strategy against hearing loss. European Journal of Pharmaceutical Sciences 187, pages 106490.
Crossref
Li Guo, Zhe Sun & Xiaoyong Ren. (2022) Preparation of PLGA nano inner ear drug delivery system and its transport mechanism in inner ears of rats. Applied Nanoscience 13:5, pages 3503-3512.
Crossref
Thu Nhan Nguyen & Jeong-Sook Park. (2022) Intratympanic drug delivery systems to treat inner ear impairments. Journal of Pharmaceutical Investigation 53:1, pages 93-118.
Crossref
Jeong-Eun Park, Woo Cheol Kim, Sung Kyun Kim, Yeji Ahn, Sun Mok Ha, Gahee Kim, Seonmin Choi, Wan Su Yun, Tae Hoon Kong, Su Hoon Lee, Dong Jun Park, Jin Sil Choi, Jaehong Key & Young Joon Seo. (2022) Protection of Hearing Loss in Ototoxic Mouse Model Through SPIONs and Dexamethasone-Loaded PLGA Nanoparticle Delivery by Magnetic Attraction. International Journal of Nanomedicine Volume 17, pages 6317-6334.
Crossref
Afsaneh Kashizadeh, Christopher Pastras, Navid Rabiee, Masoud Mohseni-Dargah, Payal Mukherjee & Mohsen Asadnia. (2022) Potential nanotechnology-based diagnostic and therapeutic approaches for Meniere's disease. Nanomedicine: Nanotechnology, Biology and Medicine 46, pages 102599.
Crossref
Zhuang Hu, Siyu Han, Nan Nie, Jiwei Wang, Jianshe Hu & Aikebaier Reheman. (2022) Preparation and drug release behavior of amphiphilic polyamino acids nanomicelles. Journal of Drug Delivery Science and Technology 76, pages 103806.
Crossref
Shreshtha Dash, Jian Zuo & Peter S. Steyger. (2022) Local Delivery of Therapeutics to the Cochlea Using Nanoparticles and Other Biomaterials. Pharmaceuticals 15:9, pages 1115.
Crossref
Kaili Chen, Fei Wang, Rui Ding, Zhengwei Cai, Tianyuan Zou, Andi Zhang, Dongye Guo, Bin Ye, Wenguo Cui & Mingliang Xiang. (2022) Adhesive and Injectable Hydrogel Microspheres for Inner Ear Treatment. Small 18:36.
Crossref
Han Li, Jing Zhu, Yan-wu Xu, Fang-fang Mou, Xiao-li Shan, Qiang-li Wang, Bao-nian Liu, Ke Ning, Jia-jia Liu, Ya-chao Wang, Jin-xia Mi, Xiaohui Wei, Shui-jin Shao, Guo-hong Cui, Rong Lu & Hai-dong Guo. (2022) Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction. Redox Biology 54, pages 102384.
Crossref
Xiaozhu Chen, Hong Zhang, Chu Wang, Yue Su, Min Xiong, Xiaohua Feng, Daishi Chen, Zhaoyang Ke, Lu Wen & Gang Chen. (2022) Curcumin-Encapsulated Chitosan-Coated Nanoformulation as an Improved Otoprotective Strategy for Ototoxic Hearing Loss. Molecular Pharmaceutics 19:7, pages 2217-2230.
Crossref
Poornima Ramburrun, Riaz A. Khan & Yahya E. Choonara. (2022) Design, preparation, and functionalization of nanobiomaterials for enhanced efficacy in current and future biomedical applications. Nanotechnology Reviews 11:1, pages 1802-1826.
Crossref
Maximilian George Dindelegan, Cristina Blebea, Maria Perde-Schrepler, Anca Dana Buzoianu & Alma Aurelia Maniu. (2022) Recent Advances and Future Research Directions for Hearing Loss Treatment Based on Nanoparticles. Journal of Nanomaterials 2022, pages 1-15.
Crossref
Julia Clara Gausterer, Clara Schüßler & Franz Gabor. (2021) The impact of calcium phosphate on FITC-BSA loading of sonochemically prepared PLGA nanoparticles for inner ear drug delivery elucidated by two different fluorimetric quantification methods. Ultrasonics Sonochemistry 79, pages 105783.
Crossref
Devon C. Pawley, Stefania Goncalves, Esperanza Bas, Emre Dikici, Sapna K. Deo, Sylvia Daunert & Fred Telischi. (2021) Dexamethasone (DXM)‐Coated Poly(lactic‐ co ‐glycolic acid) (PLGA) Microneedles as an Improved Drug Delivery System for Intracochlear Biodegradable Devices . Advanced Therapeutics 4:11.
Crossref
Bhawna Chopra & Ashwani Kumar Dhingra. (2021) Natural products: A lead for drug discovery and development. Phytotherapy Research 35:9, pages 4660-4702.
Crossref
De Jin, Yuqin Zhang, Yuehong Zhang, Liyun Duan, Rongrong Zhou, Yingyin Duan, Yuting Sun, Fengmei Lian & Xiaolin Tong. (2021) Panax Ginseng C.A.Mey. as Medicine: The Potential Use of Panax Ginseng C.A.Mey. as a Remedy for Kidney Protection from a Pharmacological Perspective. Frontiers in Pharmacology 12.
Crossref
Céline Jaudoin, Florence Agnely, Yann Nguyen, Evelyne Ferrary & Amélie Bochot. (2021) Nanocarriers for drug delivery to the inner ear: Physicochemical key parameters, biodistribution, safety and efficacy. International Journal of Pharmaceutics 592, pages 120038.
Crossref
Salman Ahmad Mustfa, Eleonora Maurizi, John McGrath & Ciro Chiappini. (2020) Nanomedicine Approaches to Negotiate Local Biobarriers for Topical Drug Delivery. Advanced Therapeutics 4:1.
Crossref
Xiaogang An & Dingjun Zha. (2020) Development of nanoparticle drug-delivery systems for the inner ear. Nanomedicine 15:20, pages 1981-1993.
Crossref
Gayeon You, Youngjun Kim, Joo Hang Lee, Jihyeon Song & Hyejung Mok. (2020) Exosome-modified PLGA Microspheres for Improved Internalization into Dendritic Cells and Macrophages. Biotechnology and Bioprocess Engineering 25:4, pages 521-527.
Crossref
Xiaobing Li, Nan Mo & Zhenzhen Li. (2020) Ginsenosides: potential therapeutic source for fibrosis-associated human diseases. Journal of Ginseng Research 44:3, pages 386-398.
Crossref
Christopher Rathnam, Sy-Tsong Dean Chueng, Yu-Lan Mary Ying, Ki-Bum Lee & Kelvin Kwan. (2019) Developments in Bio-Inspired Nanomaterials for Therapeutic Delivery to Treat Hearing Loss. Frontiers in Cellular Neuroscience 13.
Crossref
Shan Ding, Shibao Xie, Weiquan Chen, Lu Wen, Junyi Wang, Fan Yang & Gang Chen. (2019) Is oval window transport a royal gate for nanoparticle delivery to vestibule in the inner ear?. European Journal of Pharmaceutical Sciences 126, pages 11-22.
Crossref
Catalano Enrico. 2019. 91 123 .
Karsten Mäder, Eric Lehner, Arne Liebau & Stefan K. Plontke. (2018) Controlled drug release to the inner ear: Concepts, materials, mechanisms, and performance. Hearing Research 368, pages 49-66.
Crossref
Wenli Pan, Binli Xue, Chulei Yang, Linlin Miao, Lingli Zhou, Qiuyue Chen, Qing Cai, Yi Liu, Dongchun Liu, Haibing He, Yu Zhang, Tian Yin & Xing Tang. (2018) Biopharmaceutical characters and bioavailability improving strategies of ginsenosides. Fitoterapia 129, pages 272-282.
Crossref
Xiaoping Du, Qunfeng Cai, Matthew B. West, Ibrahima Youm, Xiangping Huang, Wei Li, Weihua Cheng, Don Nakmali, Donald L. Ewert & Richard D. Kopke. (2018) Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs. Molecular Therapy 26:5, pages 1313-1326.
Crossref
Umberto M. Musazzi, Silvia Franzé & Francesco Cilurzo. (2017) Innovative pharmaceutical approaches for the management of inner ear disorders. Drug Delivery and Translational Research 8:2, pages 436-449.
Crossref
Jie Qiu, Guoqiang Cai, Xinmei Liu & Dongwen Ma. (2017) αvβ3 integrin receptor specific peptide modified, salvianolic acid B and panax notoginsenoside loaded nanomedicine for the combination therapy of acute myocardial ischemia. Biomedicine & Pharmacotherapy 96, pages 1418-1426.
Crossref
Yongxin Zhang, Yaocun Yue & Meng Chang. (2017) Local anaesthetic pain relief therapy: In vitro and in vivo evaluation of a nanotechnological formulation co-loaded with ropivacaine and dexamethasone. Biomedicine & Pharmacotherapy 96, pages 443-449.
Crossref
Hui Cai, Zhongping Liang, Wenli Huang, Lu Wen & Gang Chen. (2017) Engineering PLGA nano-based systems through understanding the influence of nanoparticle properties and cell-penetrating peptides for cochlear drug delivery. International Journal of Pharmaceutics 532:1, pages 55-65.
Crossref
Ibrahima Youm, Matthew B. West, Wei Li, Xiaoping Du, Donald L. Ewert & Richard D. Kopke. (2017) siRNA-loaded biodegradable nanocarriers for therapeutic MAPK1 silencing against cisplatin-induced ototoxicity. International Journal of Pharmaceutics 528:1-2, pages 611-623.
Crossref
Filippo Valente, Laura Astolfi, Edi Simoni, Serena Danti, Valeria Franceschini, Milvia Chicca & Alessandro Martini. (2017) Nanoparticle drug delivery systems for inner ear therapy: An overview. Journal of Drug Delivery Science and Technology 39, pages 28-35.
Crossref
Dong-Kee Kim. (2017) Nanomedicine for Inner Ear Diseases: A Review of Recent In Vivo Studies . BioMed Research International 2017, pages 1-6.
Crossref
Sana Javed, Ameema Tariq, Touqeer Ahmed, Barbara Budzyńska, Silvia Tejada, Maria Daglia, Seyed Fazel NabaviEduardo Sobarzo-Sánchez & Seyed Mohammad Nabavi. (2016) Tanshinones and mental diseases: from chemistry to medicine. Reviews in the Neurosciences 27:8, pages 777-791.
Crossref
Jeong-Jun Lee, Suyeong Nam, Ju-Hwan Park, Song Yi Lee, Jae Young Jeong, Jae-Young Lee, Wie-Soo Kang, In-Soo Yoon, Dae-Duk Kim & Hyun-Jong Cho. (2016) Nanocomposites based on Soluplus and Angelica gigas Nakai extract fabricated by an electrohydrodynamic method for oral administration. Journal of Colloid and Interface Science 484, pages 146-154.
Crossref
Sergio Martín-Saldaña, Raquel Palao-Suay, Almudena Trinidad, María Rosa Aguilar, Rafael Ramírez-Camacho & Julio San Román. (2016) Otoprotective properties of 6α-methylprednisolone-loaded nanoparticles against cisplatin: In vitro and in vivo correlation. Nanomedicine: Nanotechnology, Biology and Medicine 12:4, pages 965-976.
Crossref
Naila El Kechai, Florence Agnely, Elisabeth Mamelle, Yann Nguyen, Evelyne Ferrary & Amélie Bochot. (2015) Recent advances in local drug delivery to the inner ear. International Journal of Pharmaceutics 494:1, pages 83-101.
Crossref
Bing Wang, Yiqiong Pu, Benliang Xu, Jiansheng Tao, Yuqin WangTong Zhang & Peiying Wu. (2015) Self-microemulsifying Drug Delivery System Improved Oral Bioavailability of 20(<i>S</i>)-Protopanaxadiol: From Preparation to Evaluation. CHEMICAL & PHARMACEUTICAL BULLETIN Chemical and Pharmaceutical Bulletin 63:9, pages 688-693.
Crossref