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Journal of Pain Research Volume 13, 2020 - Issue
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Original Research

The Use of a New Food-Grade Lecithin Formulation of Highly Standardized Ginger (Zingiber officinale) and Acmella oleracea Extracts for the Treatment of Pain and Inflammation in a Group of Subjects with Moderate Knee Osteoarthritis

Mariangela Rondanelli1 IRCCS Mondino Foundation, Pavia27100, Italy;2 Department of Public Health, Experimental and Forensic Medicine, Unit of Human and Clinical Nutrition, University of Pavia, Pavia27100, ItalyView further author information
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Antonella Riva3 Research and Development Unit, Indena, Milan20146, ItalyORCID Iconhttps://orcid.org/0000-0003-2819-943XView further author information
ORCID Icon,
Pietro Allegrini3 Research and Development Unit, Indena, Milan20146, ItalyORCID Iconhttps://orcid.org/0000-0002-4380-9577View further author information
ORCID Icon,
Milena Anna Faliva4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyView further author information
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Maurizio Naso4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyView further author information
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Gabriella Peroni4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyORCID Iconhttps://orcid.org/0000-0002-1632-1787View further author information
ORCID Icon,
Mara Nichetti4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyView further author information
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Clara Gasparri4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyView further author information
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Daniele Spadaccini4 Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita”, University of Pavia, Pavia27100, ItalyORCID Iconhttps://orcid.org/0000-0001-6413-9253View further author information
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Giancarlo Iannello5 General Management, Azienda di Servizi alla Persona “Istituto Santa Margherita”, Pavia27100, ItalyView further author information
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Vittoria Infantino6 Department of Biomedical Science and Human Oncology, University of Bari Aldo Moro, Bari70121, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8172-5182View further author information
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Teresa Fazia7 Department of Brain and Behavioral Science, University of Pavia, Pavia, ItalyORCID Iconhttps://orcid.org/0000-0002-9577-8450View further author information
ORCID Icon,
Luisa Bernardinelli7 Department of Brain and Behavioral Science, University of Pavia, Pavia, ItalyORCID Iconhttps://orcid.org/0000-0002-7551-6664View further author information
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Simone Perna8 Department of Biology, College of Science, University of Bahrain, Sakhir Campus, Kingdom of BahrainORCID Iconhttps://orcid.org/0000-0002-2720-1473View further author information
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Pages 761-770 | Published online: 21 Apr 2020

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Mahmood Barani, Enrico Sangiovanni, Marco Angarano, Mohammad Amin Rajizadeh, Mehrnaz Mehrabani, Stefano Piazza, Hosahalli Veerabhadrappa Gangadharappa, Abbas Pardakhty, Mehrzad Mehrbani, Mario Dell’Agli & Mohammad Hadi Nematollahi. (2021) Phytosomes as Innovative Delivery Systems for Phytochemicals: A Comprehensive Review of Literature. International Journal of Nanomedicine 16, pages 6983-7022.
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Articles from other publishers (12)

Mariana Deleanu, Laura Toma, Gabriela Maria Sanda, Teodora Barbălată, Loredan Ştefan Niculescu, Anca Volumnia Sima, Calin Deleanu, Liviu Săcărescu, Alexandru Suciu, Georgeta Alexandru, Iuliana Crişan, Mariana Popescu & Camelia Sorina Stancu. (2023) Formulation of Phytosomes with Extracts of Ginger Rhizomes and Rosehips with Improved Bioavailability, Antioxidant and Anti-Inflammatory Effects In Vivo. Pharmaceutics 15:4, pages 1066.
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Christian Matthews & Jennifer Oberstar. (2023) Does ginger supplementation improve knee pain and function in patients with known knee osteoarthritis?. Evidence-Based Practice Publish Ahead of Print.
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Benjamin Gilbert, Lúcio Ferreira Alves & Rita de Fátima FavoretoBenjamin Gilbert, Lúcio Ferreira Alves & Rita de Fátima Favoreto. 2022. Monografias de Plantas Medicinais Brasileiras e Aclimatadas: Volume II. Monografias de Plantas Medicinais Brasileiras e Aclimatadas: Volume II 17 36 .
Paolo Poli, Simona Carnevale, Antonella Scocca, Pier Luigi Davolio, Simona Busi, Martino Meneghin, Giovanna Petrangolini & Antonella Riva. (2022) Promising Health Benefits of Adjuvant Acmella and Zingiber Extracts Combined with Coenzyme Q10 Phytosomes, Supplementation in Chronic Pain Treated with Medical Cannabis: A Prospective and Open-Label Clinical Study. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-6.
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Diorge Jônatas Marmitt. (2022) Potential plants for inflammatory dysfunction in the SARS-CoV-2 infection. Inflammopharmacology 30:3, pages 749-773.
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Panyun Mu, Jie Feng, Yimei Hu, Feng Xiong, Xu Ma & Linling Tian. (2022) Botanical Drug Extracts Combined With Biomaterial Carriers for Osteoarthritis Cartilage Degeneration Treatment: A Review of 10 Years of Research. Frontiers in Pharmacology 12.
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Bhanumati SarkarSanjib Kumar Das, Rakesh Acharya & Koushik Sen. 2022. The Basic Handbook of Indian Ethnobotany and Traditional Medicine. The Basic Handbook of Indian Ethnobotany and Traditional Medicine 96 136 .
Marco Bardelli, Stefano Gentileschi, Bruno Frediani & Maurizio Benucci. (2021) Integration with Spilanthes Achmella in fibromyalgia syndrome: open-label study six months after the treatment. Beyond Rheumatology 3:3.
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Selma Delgado de Souza Moro, Lucas Fujii, Luis Felipe Rodrigues Teodoro, Katleen Frauz, Alysson Fernandes Mazoni, Marcelo Augusto Maretto Esquisatto, Rodney Alexandre Ferreira Rodrigues, Edson Rosa Pimentel & Andrea Aparecida Aro. (2021) Acmella oleracea extract increases collagen content and organization in partially transected tendons . Microscopy Research and Technique 84:11, pages 2588-2597.
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Sara Hassan Hassan Ahmed, Tímea Gonda & Attila Hunyadi. (2021) Medicinal chemistry inspired by ginger: exploring the chemical space around 6-gingerol. RSC Advances 11:43, pages 26687-26699.
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Reham Hamza, Fawziah Al-Salmi & Nahla El-Shenawy. (2020) Chitosan and Lecithin Ameliorate Osteoarthritis Symptoms Induced by Monoiodoacetate in a Rat Model. Molecules 25:23, pages 5738.
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Breanna N. Lindler, Katelyn E. Long, Nancy A. Taylor & Wei Lei. (2020) Use of Herbal Medications for Treatment of Osteoarthritis and Rheumatoid Arthritis. Medicines 7:11, pages 67.
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