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Review

Liposomal bupivacaine: a review of a new bupivacaine formulation

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Pages 257-264 | Published online: 14 Aug 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (15)

Abdelkader Ammam, Hafidh Zemour, M’hamed Kaid, Didier Villemin, Walid Soufan & Fathi Abdellatif Belhouadjeb. (2023) Assessment of the anti-inflammatory and analgesic effects of Opuntia ficus indica L. Cladodes extract. Libyan Journal of Medicine 18:1.
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Maria Escudero-Fung, Erik B Lehman & Kunal Karamchandani. (2020) Timing of Transversus Abdominis Plane Block and Postoperative Pain Management. Local and Regional Anesthesia 13, pages 185-193.
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Öznur Güngör, İmren Özcan, Mehmet Ali Erdoğan, Burhan Ateş & Süleyman Köytepe. (2020) Differential Pulse Voltammetric (DPV) Determination of the Local Anesthetic Bupivacaine using Polyimide Membrane-Based Electrodes. Analytical Letters 53:2, pages 228-244.
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Daniele Ribeiro de Araújo, Lígia Nunes de Morais Ribeiro & Eneida de Paula. (2019) Lipid-based carriers for the delivery of local anesthetics. Expert Opinion on Drug Delivery 16:7, pages 701-714.
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Shankar Raman, Mayin Lin & Nivedita Krishnan. (2018) Systematic review and meta-analysis of the efficacy of liposomal bupivacaine in colorectal resections. Journal of Drug Assessment 7:1, pages 43-50.
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Kammy KS Poon & Steven HS Wong. (2017) New and developing anesthesia drugs. Expert Opinion on Pharmacotherapy 18:2, pages 195-204.
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C. S. Kirkness, C. V. Asche, J. Ren, K. Gordon, P. Maurer, B. Maurer & B. T. Maurer. (2016) Assessment of liposome bupivacaine infiltration versus continuous femoral nerve block for postsurgical analgesia following total knee arthroplasty: a retrospective cohort study. Current Medical Research and Opinion 32:10, pages 1727-1733.
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Admir Hadzic, John A Abikhaled & William J Harmon. (2015) Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine. Local and Regional Anesthesia 8, pages 105-111.
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Girish P Joshi, Gary Patou & Vladimir Kharitonov. (2015) The safety of liposome bupivacaine following various routes of administration in animals. Journal of Pain Research 8, pages 781-789.
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Ushma Shah, David T Wong & Jean Wong. (2015) Patient satisfaction and positive patient outcomes in ambulatory anesthesia. Ambulatory Anesthesia 2, pages 29-37.
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Herman Sehmbi, Jean Wong & David T Wong. (2015) Perspectives on ambulatory anesthesia: the patient’s point of view. Ambulatory Anesthesia 2, pages 1-9.
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Pamela Palmer. (2015) Novel pharmaceuticals in the management of postoperative pain. Expert Review of Clinical Pharmacology 8:5, pages 511-513.
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Jonathan F. Bova, Anderson F. da Cunha, Rhett W. Stout, Sarindr Bhumiratana, David M. Alfi, Sidney B. Eisig, Gordana Vunjak-Novakovic & Mandi J. Lopez. (2015) Bupivacaine Mandibular Nerve Block Affects Intraoperative Blood Pressure and Heart Rate in a Yucatan Miniature Swine Mandibular Condylectomy Model: A Pilot Study. Journal of Investigative Surgery 28:1, pages 32-39.
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Mark Lambrechts, Michael J O’Brien, Felix H Savoie & Zongbing You. (2013) Liposomal extended-release bupivacaine for postsurgical analgesia. Patient Preference and Adherence 7, pages 885-890.
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Articles from other publishers (26)

Ashley S. Moon, Vaagn Andikyan, Rakhee Agarwal, Stephanie Stroever, David Misita, Anya Laibangyang, David Doo & Linus T. Chuang. (2023) Incisional infiltration versus transversus abdominis plane block of liposomal bupivacaine after midline vertical laparotomy for suspected gynecologic malignancy: a pilot study. Gynecologic Oncology Reports, pages 101203.
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Ryan N. Hellums, Matthew D. Adams, Nicholas C. Purdy & Timothy L. Lindemann. (2022) Impact of Liposomal Bupivacaine on Post-Operative Pain and Opioid Usage in Thyroidectomy. Annals of Otology, Rhinology & Laryngology 132:1, pages 77-81.
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Ga-Eul Chae, Dong Woo Kim & Hyo-Eon Jin. (2022) Development of Squalene-Based Oil-in-Water Emulsion Adjuvants Using a Self-Emulsifying Drug Delivery System for Enhanced Antigen-Specific Antibody Titers. International Journal of Nanomedicine Volume 17, pages 6221-6231.
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Caroline Billings & David E. Anderson. (2022) Comparison of three methods for assessment of drug elution: In vitro elution of gentamicin from a collagen-based scaffold. Frontiers in Drug Delivery 2.
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Ryan Krupp, Austin Smith, John Nyland, Colton Mojesky, Deandrea Perkins & Leah Y. Carreon. (2022) Liposomal bupivacaine nerve block provides better pain control post-total shoulder arthroplasty than continuous indwelling catheter. Archives of Orthopaedic and Trauma Surgery 143:4, pages 1895-1902.
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Lauren Jindia, Justin Christensen, Jin Deng, Suvikram Puri, Maha Balouch, George Haidamous, Mark Frankle & Enrico Mario Camporesi. (2022) Opioid Sparing at 24 h after Total Shoulder Arthroplasty by Undiluted Liposomal Bupivacaine Single Shot Interscalene Block: A Randomized Clinical Trial, First Results. Surgeries 3:1, pages 64-70.
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Alexander Zeh. 2022. Basics in Primary Knee Arthroplasty. Basics in Primary Knee Arthroplasty 475 489 .
Jasper G. Steverink, Susanna Piluso, Jos Malda & Jorrit-Jan Verlaan. (2021) Comparison of in vitro and in vivo Toxicity of Bupivacaine in Musculoskeletal Applications. Frontiers in Pain Research 2.
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Hyebin Yoo, Jun Seok Park, Seung Soo Oh & Hyun Kang. (2021) Osmotically balanced, large unilamellar liposomes that enable sustained bupivacaine release for prolonged pain relief in in vivo rat models. Scientific Reports 11:1.
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Brandon T. Stryder, Paulina M. Szakiel, Michael Kelly, Henry T. Shu, Blake M. Bodendorfer, Stephen Luck & Evan H. Argintar. (2021) Reduced Opioid Use Among Patients Who Received Liposomal Bupivacaine for ACL Reconstruction. Orthopedics 44:2.
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D. V. Sliusarenko, М. G. Ilnitskiy, D. D. Bilyi, O. M. Bobrytska & L. O. Kovalova. (2021) Regional anesthesiological support for the implementation of surgical interventions in the abdomen of dogs. Regulatory Mechanisms in Biosystems 12:1, pages 50-57.
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Alan David Kaye, Cassandra Armstead-Williams, Farees Hyatali, Katherine S. Cox, Rachel J. Kaye, Lauren K. Eng, Muhammad A. Farooq Anwar, Perene V. Patel, Shilpa Patil & Elyse M. Cornett. (2020) Exparel for Postoperative Pain Management: a Comprehensive Review. Current Pain and Headache Reports 24:11.
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Lucio Cipollaro, Paolo Trucillo, Nicola Luigi Bragazzi, Giovanna Della Porta, Ernesto Reverchon & Nicola Maffulli. (2020) Liposomes for Intra-Articular Analgesic Drug Delivery in Orthopedics: State-of-Art and Future Perspectives. Insights from a Systematic Mini-Review of the Literature. Medicina 56:9, pages 423.
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Alan David Kaye, Matthew B. Novitch, Sam F. Carlson, Mitchell C. Fuller, Shane W. White, Alexander R. Haroldson, Jennifer A. Kaiser, Mohamed A. Elkersh, Andrew J. Brunk, George M. Jeha & Elyse M. Cornett. (2020) The Role of Exparel Plus Meloxicam for Postoperative Pain Management. Current Pain and Headache Reports 24:3.
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Christopher A. R. Chapman, Estelle A. Cuttaz, Josef A. Goding & Rylie A. Green. (2020) Actively controlled local drug delivery using conductive polymer-based devices. Applied Physics Letters 116:1.
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Travis Farmer, S. Craig Morris, Robert Quigley, Nirav H. Amin, Montri D. Wongworawat & Hasan M. Syed. (2020) Chondrotoxicity of Local Anesthetics: Liposomal Bupivacaine Is Less Chondrotoxic than Standard Bupivacaine. Advances in Pharmacological and Pharmaceutical Sciences 2020, pages 1-6.
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Keegan Guidolin & Gang Zheng. (2019) Nanomedicines Lost in Translation. ACS Nano 13:12, pages 13620-13626.
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E. Viscusi, H. Minkowitz, P. Winkle, S. Ramamoorthy, J. Hu & N. Singla. (2019) HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in herniorrhaphy: results from the phase 3 EPOCH 2 study. Hernia 23:6, pages 1071-1080.
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Jorien Iliaens, Willem-Jan Metsemakers, Steve Coppens, Harm Hoekstra, An Sermon, Marc Van de Velde & Stefaan Nijs. (2019) Regional anaesthesia for surgical repair of proximal humerus fractures: a systematic review and critical appraisal. Archives of Orthopaedic and Trauma Surgery 139:12, pages 1731-1741.
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Carole Lin, Curtis Darling & Ban C. H. Tsui. (2019) Practical Regional Anesthesia Guide for Elderly Patients. Drugs & Aging 36:3, pages 213-234.
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Aaron B. Parrish, Sean M. O’Neill, Steven R. Crain, Tara A. Russell, Deepak K. Sonthalia, Vu T. Nguyen & Armen Aboulian. (2018) An Enhanced Recovery After Surgery (ERAS) Protocol for Ambulatory Anorectal Surgery Reduced Postoperative Pain and Unplanned Returns to Care After Discharge. World Journal of Surgery 42:7, pages 1929-1938.
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Alysha Moretti, Bin Zhang, Bernice Lee, Meenakshi Dutt & Kathryn E. Uhrich. (2017) Degree of Unsaturation and Backbone Orientation of Amphiphilic Macromolecules Influence Local Lipid Properties in Large Unilamellar Vesicles. Langmuir 33:51, pages 14663-14673.
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Elliot V. Hersh, Mana Saraghi & Paul A. Moore. (2017) Two Recent Advances in Local Anesthesia: Intranasal Tetracaine/Oxymetazoline and Liposomal Bupivacaine. Current Oral Health Reports 4:3, pages 189-196.
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MC Ott. (2017) Efficacy of Liposomal Bupivacaine in Orthopedic Procedures in an Academic Trauma Hospital. Annals of Musculoskeletal Medicine 1:2, pages 027-031.
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Emanuel A. Shapera & Vinay K. Rai. (2016) A Content Incontinent: Report of Liposomal Bupivacaine Induced Fecal Incontinence. Case Reports in Surgery 2016, pages 1-3.
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Juan Portillo, Nawal Kamar, Somayah Melibary, Eduardo Quevedo & Sergio Bergese. (2014) Safety of liposome extended-release bupivacaine for postoperative pain control. Frontiers in Pharmacology 5.
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