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Original Research

MicroRNA-216a promotes the metastasis and epithelial–mesenchymal transition of ovarian cancer by suppressing the PTEN/AKT pathway

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Pages 2701-2709 | Published online: 23 May 2017

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Huilin Zhang & Bingjian Lu. (2020) microRNAs as biomarkers of ovarian cancer. Expert Review of Anticancer Therapy 20:5, pages 373-385.
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Zhengling Liu, Zonglan Xu, Yonghui Tian, Hua Yan & Yanyan Lou. (2019) ZNF277 regulates ovarian cancer cell proliferation and invasion through inhibition of PTEN. OncoTargets and Therapy 12, pages 3031-3042.
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Yanghua Fan, Yu He, Xi Zhou, Yong Liu & Fu Wang. (2019) Meta-analysis of the prognostic value of lncRNA DANCR for cancer patients in China. Cancer Management and Research 11, pages 2027-2037.
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Laraib Zara, Rizwana Hussain, Muhammad Shareef Masoud, Nadia Naseem, Hafiz Usman Ahmad, Usman Ali Ashfaq & Saba Khaliq. (2023) Dysregulation of gene expression of PTEN and AKT signaling pathway in patients of ovarian cancer: A pilot study. Journal of King Saud University - Science 35:1, pages 102378.
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Qin LI, Junyu SHI & Xiaoli XU. (2021) MicroRNA-1271-5p inhibits the tumorigenesis of ovarian cancer through targeting E2F5 and negatively regulates the mTOR signaling pathway. Panminerva Medica 63:3.
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Kaiying Cui & Genhai Zhu. (2020) LncRNA CTBP1-AS2 regulates miR-216a/ PTEN to suppress ovarian cancer cell proliferation. Journal of Ovarian Research 13:1.
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Andrea Lampis, Jens C Hahne, Somaieh Hedayat & Nicola Valeri. (2020) MicroRNAs as mediators of drug resistance mechanisms. Current Opinion in Pharmacology 54, pages 44-50.
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Ping Wang, Qiong Liu, Hongwei Zhao, Jack Owen Bishop, Guoli Zhou, L. Karl Olson & Anna Moore. (2020) miR-216a-targeting theranostic nanoparticles promote proliferation of insulin-secreting cells in type 1 diabetes animal model. Scientific Reports 10:1.
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Virginia Álvarez-Garcia, Yasmine Tawil, Helen M. Wise & Nicholas R. Leslie. (2019) Mechanisms of PTEN loss in cancer: It’s all about diversity. Seminars in Cancer Biology 59, pages 66-79.
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Guang‐Cai Li, Xu‐Ling Qin, Huai‐Hua Song, Ying‐Ni Li, Yu‐Yan Qiu, Shi‐Chang Cui, Yong‐Sheng Wang, Hui Wang & Jun‐Ling Gong. (2019) Retracted : Upregulated microRNA‐15b alleviates ovarian cancer through inhitbition of the PI3K/Akt pathway by targeting LPAR3 . Journal of Cellular Physiology 234:12, pages 22331-22342.
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Hui Zhang, Aixiang Liu, Xielin Feng, Lang Tian, Wentao Bo, Haiqing Wang & Yong Hu. (2019) MiR-132 promotes the proliferation, invasion and migration of human pancreatic carcinoma by inhibition of the tumor suppressor gene PTEN. Progress in Biophysics and Molecular Biology 148, pages 65-72.
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Juelan Wang, Wenqian Xu, Yangke He, Qi Xia & Siwei Liu. (2018) LncRNA MEG3 impacts proliferation, invasion, and migration of ovarian cancer cells through regulating PTEN. Inflammation Research 67:11-12, pages 927-936.
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Wenzhao Hang, Yiwen Feng, Zhenyu Sang, Ye Yang, Yaping Zhu, Qian Huang & Xiaowei Xi. (2018) Downregulation of miR-145-5p in cancer cells�and their�derived exosomes may contribute to�the�development of ovarian cancer by targeting CT. International Journal of Molecular Medicine.
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Xinping Xie, Yuxiu Huang, Lihong Chen & Jinhua Wang. (2018) miR‑221 regulates proliferation and apoptosis of ovarian cancer cells by targeting BMF. Oncology Letters.
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Dan‑Tong Liu, Hai‑Rong Yao, Yan‑Ying Li, Yang‑Yang Song & Meng‑Ya Su. (2018) MicroRNA‑19b promotes the migration and invasion of ovarian cancer cells by inhibiting the PTEN/AKT signaling pathway. Oncology Letters.
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Dongdong Wei, Yingbin Miao, Lianxia Yu, Degong Wang & Yingli Wang. (2018) Downregulation of microRNA‑198 suppresses cell proliferation and invasion in retinoblastoma by directly targeting PTEN. Molecular Medicine Reports.
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Yinfang Wu, Jun Zhang, Yu Zheng, Cheng Ma, Xing-E Liu & Xiaodong Sun. (2018) miR-216a-3p Inhibits the Proliferation, Migration, and Invasion of Human Gastric Cancer Cells via Targeting RUNX1 and Activating the NF-κB Signaling Pathway. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 26:1, pages 157-171.
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