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Review

Improving diabetes medication adherence: successful, scalable interventions

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Pages 139-149 | Published online: 23 Jan 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Yen-Ming Huang, Olayinka O. Shiyanbola, Hsun-Yu Chan & Paul D. Smith. (2020) Patient factors associated with diabetes medication adherence at different health literacy levels: a cross-sectional study at a family medicine clinic. Postgraduate Medicine 132:4, pages 328-336.
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Tessa Kennedy-Martin, Kristina S Boye & Xiaomei Peng. (2017) Cost of medication adherence and persistence in type 2 diabetes mellitus: a literature review. Patient Preference and Adherence 11, pages 1103-1117.
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Bruck Messele Habte, Tedla Kebede, Teferi Gedif Fenta & Heather Boon. (2017) Ethiopian patients’ perceptions of anti-diabetic medications: implications for diabetes education. Journal of Pharmaceutical Policy and Practice 10:1.
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Fernando J Lavalle-González & Erwin Chiquete. (2016) Patients’ empowerment, physicians’ perceptions, and achievement of therapeutic goals in patients with type 1 and type 2 diabetes mellitus in Mexico. Patient Preference and Adherence 10, pages 1349-1357.
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William H Polonsky & Robert R Henry. (2016) Poor medication adherence in type 2 diabetes: recognizing the scope of the problem and its key contributors. Patient Preference and Adherence 10, pages 1299-1307.
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Leah L Zullig, Bradi B Granger & Hayden B Bosworth. (2016) A renewed Medication Adherence Alliance call to action: harnessing momentum to address medication nonadherence in the United States. Patient Preference and Adherence 10, pages 1189-1195.
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Gerda Längst, Hanna Marita Seidling, Marion Stützle, Dominik Ose, Ines Baudendistel, Joachim Szecsenyi, Michel Wensing & Cornelia Mahler. (2015) Factors associated with medication information in diabetes care: differences in perceptions between patients and health care professionals. Patient Preference and Adherence 9, pages 1431-1441.
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Articles from other publishers (46)

Paula M. Trief, Diane Uschner, Seth Kalichman, Barbara J. Anderson, Lida M. Fette, Hui Wen, Jane D. Bulger & Ruth S. Weinstock. (2023) Psychosocial factors predict medication adherence in young adults with youth‐onset type 2 diabetes: Longitudinal results from the TODAY2 i Count study . Diabetic Medicine 40:5.
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Charity Ngoatle, Lina S. Hlahla, Mabitsela H. Mphasha, Tebogo M. Mothiba & Mahlapahlapana J. Themane. (2023) Does Health Literacy Have an Impact on Adherence to Diabetes Mellitus Treatment?. Endocrines 4:1, pages 82-92.
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Paula M. Trief, Seth Kalichman, Diane Uschner, Melinda Tung, Kimberly L. Drews, Barbara J. Anderson, Lida M. Fette, Hui Wen, Jane D. Bulger & Ruth S. Weinstock. (2022) Association of psychosocial factors with medication adherence in emerging adults with youth‐onset type 2 diabetes: The i Count study . Pediatric Diabetes 23:8, pages 1695-1706.
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Allison A. Lewinski, Shelley A. Jazowski, Karen M. Goldstein, Colette Whitney, Hayden B. Bosworth & Leah L. Zullig. (2022) Intensifying approaches to address clinical inertia among cardiovascular disease risk factors: A narrative review. Patient Education and Counseling 105:12, pages 3381-3388.
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Athanasios Chantzaras & John Yfantopoulos. (2022) Association between medication adherence and health-related quality of life of patients with diabetes. Hormones 21:4, pages 691-705.
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Jean de Dieu Murwanashyaka, Albert Ndagijimana, Emmanuel Biracyaza, François Xavier Sunday & Maryse Umugwaneza. (2022) Non-adherence to medication and associated factors among type 2 diabetes patients at Clinique Medicale Fraternite, Rwanda: a cross-sectional study. BMC Endocrine Disorders 22:1.
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Stijn Hogervorst, Marcia Vervloet, Marcel C. Adriaanse, Karen Zamboni, Leah L. Zullig, Linda Schoonmade, Jacqueline G. Hugtenburg & Liset van Dijk. (2022) Scalability of effective adherence interventions for patients using cardiovascular disease medication: A realist synthesis‐inspired systematic review. British Journal of Clinical Pharmacology.
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Sanusi Sani, Md. Sayeed Akhtar, Prem Kapur, Gunjan Sharma, Fauzia Tabassum, Mohd Faiyaz Khan & Manju Sharma. (2022) Evaluation of Prescribing Pattern, Therapeutic Adherence and Occurrence of Adverse Drug Reactions in Patients with Type 2 Diabetes Mellitus. Current Drug Therapy 17:3, pages 177-185.
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Lyndsay A. Nelson, Andrew J. Spieker, Sunil Kripalani, Russell L. Rothman, Christianne L. Roumie, Joseph Coco, Daniel Fabbri, Phillip Levy, Sean P. Collins & Candace D. McNaughton. (2022) User preferences for and engagement with text messages to support antihypertensive medication adherence: Findings from a pilot study evaluating an emergency department-based behavioral intervention. Patient Education and Counseling 105:6, pages 1606-1613.
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Kristen E Gray, Katherine D Hoerster, Leslie Taylor, James Krieger & Karin M Nelson. (2021) Improvements in physical activity and some dietary behaviors in a community health worker-led diabetes self-management intervention for adults with low incomes: results from a randomized controlled trial. Translational Behavioral Medicine 11:12, pages 2144-2154.
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Karen McGuigan, Alyson Hill, Deirdre McCay, Maurice O’Kane & Vivien Coates. (2021) Overcoming Barriers to Injectable Therapies: Development of the ORBIT Intervention Within a Behavioural Change Framework. Frontiers in Clinical Diabetes and Healthcare 2.
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Yen-Ming Huang & Olayinka O. Shiyanbola. (2021) Investigation of Barriers and Facilitators to Medication Adherence in Patients With Type 2 Diabetes Across Different Health Literacy Levels: An Explanatory Sequential Mixed Methods Study. Frontiers in Pharmacology 12.
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Madhur Verma, Priyanka Sharma, Atul Chaudhari, Meenakshi Sharma & Sanjay Kalra. (2021) Effect of Lockdown on Diabetes Care During the COVID-19 Pandemic: Result of a Telephone-Based Survey Among Patients Attending a Diabetic Clinic in Northern India. Cureus.
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Sebastian Schneeweiss & Elisabetta Patorno. (2021) Conducting Real-world Evidence Studies on the Clinical Outcomes of Diabetes Treatments. Endocrine Reviews 42:5, pages 658-690.
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Tariku Shimels, Melesse Abebaw & Gebremedhin Beedemariam Gebretekle. (2021) Poor Adherence to Common Recommendations and Associated Factors among Outpatients with Type 2 Diabetes Mellitus in a Police Hospital of Ethiopia. Journal of Social Health and Diabetes 9:01, pages e8-e14.
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Mingmin Zhao, Kreshnik Hoti, Hao Wang, Aniruddh Raghu & Dina Katabi. (2021) Assessment of medication self-administration using artificial intelligence. Nature Medicine 27:4, pages 727-735.
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Felipe Martins de Oliveira, Luís Eduardo Procópio Calliari, Cecília Kauffman Rutenberg Feder, Maria Fernanda Ozorio de Almeida, Mariana Vilela Pereira, Maria Thereza Teixeira de Almeida Fagundes Alves, Sônia Aparecida Dias Garcia, Ligia Dinara Donizeti Reis & João Eduardo Nunes Salles. (2021) Efficacy of a glucose meter connected to a mobile app on glycemic control and adherence to self-care tasks in patients with T1DM and LADA: a parallel-group, open-label, clinical treatment trial. Archives of Endocrinology and Metabolism.
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Charity Ngoatle & Tebogo Maria Mothiba. 2021. Lifestyle and Epidemiology - Poverty and Cardiovascular Diseases a Double Burden in African Populations [Working Title]. Lifestyle and Epidemiology - Poverty and Cardiovascular Diseases a Double Burden in African Populations [Working Title].
Reema Mody, Maria Yu, Bal Nepal, Manige Konig & Michael Grabner. (2020) Adherence and persistence among patients with type 2 diabetes initiating dulaglutide compared with semaglutide and exenatide BCise : 6‐month follow‐up from US real‐world data . Diabetes, Obesity and Metabolism 23:1, pages 106-115.
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Khine Swe & S. Sethu K. Reddy. (2020) Improving Adherence in Type 2 Diabetes. Clinics in Geriatric Medicine 36:3, pages 477-489.
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Dhfer Mahdi AlShayban, Atta Abbas Naqvi, Othman Alhumaid, Ali Saad AlQahtani, Md. Ashraful Islam, Syed Azizullah Ghori, Abdul Haseeb, Majid Ali, Muhammad Shahid Iqbal, Mahmoud E. Elrggal, Azfar Athar Ishaqui, Mansour Adam Mahmoud, Irfanullah Khan & Shazia Jamshed. (2020) Association of Disease Knowledge and Medication Adherence Among Out-Patients With Type 2 Diabetes Mellitus in Khobar, Saudi Arabia. Frontiers in Pharmacology 11.
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Lynne Chepulis, Christopher Mayo, Brittany Morison, Rawiri Keenan, Chunhuan Lao, Ryan Paul & Ross Lawrenson. (2020) Metformin adherence in patients with type 2 diabetes and its association with glycated haemoglobin levels. Journal of Primary Health Care 12:4, pages 318.
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Bernhard Kulzer & Frank Petrak. 2020. Psychologie in der medizinischen Rehabilitation. Psychologie in der medizinischen Rehabilitation 327 342 .
Khaled AlQarni, Elham A. AlQarni, Atta Abbas Naqvi, Dhfer Mahdi AlShayban, Syed Azizullah Ghori, Abdul Haseeb, Mohamed Raafat & Shazia Jamshed. (2019) Assessment of Medication Adherence in Saudi Patients With Type II Diabetes Mellitus in Khobar City, Saudi Arabia. Frontiers in Pharmacology 10.
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Amit D. RavalMatthew H. NguyenSiting ZhouMichael GrabnerJohn BarronRalph Quimbo. (2019) Effect of V-Go Versus Multiple Daily Injections on Glycemic Control, Insulin Use, and Diabetes Medication Costs Among Individuals with Type 2 Diabetes Mellitus. Journal of Managed Care & Specialty Pharmacy 25:10, pages 1111-1123.
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C. Ngoatle, T.M. Mothiba & M.J. Themane. (2019) The Interpretation of Prescribed Medication Instructions by Diabetes Mellitus Patients at a Selected Clinic in the Capricorn District of Limpopo Province, South Africa: A Pilot Study. The Open Public Health Journal 12:1, pages 374-378.
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Sophie Momen & Robert Sarkany. 2019. Cutaneous Photoaging. Cutaneous Photoaging 275 314 .
Amit D. RavalMatthew H. NguyenSiting ZhouMichael GrabnerJohn BarronRalph Quimbo. (2019) Effect of V-Go Versus Multiple Daily Injections on Glycemic Control, Insulin Use, and Diabetes Medication Costs Among Individuals with Type 2 Diabetes Mellitus. Journal of Managed Care & Specialty Pharmacy, pages 1-14.
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Abhinav Sharma, Robert J. Mentz, Bradi B. Granger, John F. Heitner, Lauren B. Cooper, Dipanjan Banerjee, Cynthia L. Green, Maulik D. Majumdar, Zubin Eapen, Lori Hudson & G. Michael Felker. (2019) Utilizing mobile technologies to improve physical activity and medication adherence in patients with heart failure and diabetes mellitus: Rationale and design of the TARGET-HF-DM Trial. American Heart Journal 211, pages 22-33.
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C. Ngoatle, T. M. Mothiba & M. J. Themane. (2019) A Review of Non-Communicable Diseases (NCDs) Prescribed Medications Instructions to Promote Medication Adherence: A Document Analysis Study. The Open Public Health Journal 12:1, pages 11-15.
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Leah L. ZulligMieke Deschodt, Jan Liska, Hayden B. BosworthSabina De Geest. (2019) Moving from the Trial to the Real World: Improving Medication Adherence Using Insights of Implementation Science. Annual Review of Pharmacology and Toxicology 59:1, pages 423-445.
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Elizabeth J Unni, Eve Van Wagoner & Olayinka O Shiyanbola. (2019) Utilizing a 3S (strategies, source and setting) approach to understand the patient’s preferences when addressing medication non-adherence in patients with diabetes: a focus group study in a primary outpatient clinic. BMJ Open 9:1, pages e024789.
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Mangesh D. Kharjul, Claire Cameron & Rhiannon Braund. (2019) Using the Pharmaceutical Collection Database to identify patient adherence to oral hypoglycaemic medicines. Journal of Primary Health Care 11:3, pages 265.
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Sarah Cuschieri, Josanne Vassallo, Neville Calleja, Christopher Barbara & Julian Mamo. (2018) The interaction of dyslipidaemia with glycaemia in an adult population study. Journal of Diabetes & Metabolic Disorders 17:2, pages 315-323.
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Anna Beth BartonDaniel E. OkoroduduHayden B. BosworthMatthew J. Crowley. (2018) Clinical Inertia in a Randomized Trial of Telemedicine-Based Chronic Disease Management: Lessons Learned. Telemedicine and e-Health 24:10, pages 742-748.
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Courtney H. Van Houtven, Melissa A. Greiner, Brooke Heidenfelder, Susan E. Spratt, Bradi B. Granger, Ashley A. Dunham, Laura G. Qualls & Lesley H. Curtis. (2018) Medicare utilization, screening, and costs among participants in the Southeastern Diabetes Initiative: A population-based evaluation. Primary Care Diabetes 12:2, pages 172-183.
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Olga Horvat, Jelena Popržen, Ana Tomas, Milica Paut Kusturica, Zdenko Tomić & Ana Sabo. (2018) Factors associated with non-adherence among type 2 diabetic patients in primary care setting in eastern Bosnia and Herzegovina. Primary Care Diabetes 12:2, pages 147-154.
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Shuyan Gu, Yuhang Zeng, Demin Yu, Xiaoqian Hu & Hengjin Dong. (2016) Cost-Effectiveness of Saxagliptin versus Acarbose as Second-Line Therapy in Type 2 Diabetes in China. PLOS ONE 11:11, pages e0167190.
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Shuyan Gu, Yiming Mu, Suodi Zhai, Yuhang Zeng, Xuemei Zhen & Hengjin Dong. (2016) Cost-Effectiveness of Dapagliflozin versus Acarbose as a Monotherapy in Type 2 Diabetes in China. PLOS ONE 11:11, pages e0165629.
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Wei-Hsuan Lo-Ciganic, Julie M. Donohue, Bobby L. Jones, Subashan Perera, Joshua M. Thorpe, Carolyn T. Thorpe, Zachary A. Marcum & Walid F. Gellad. (2016) Trajectories of Diabetes Medication Adherence and Hospitalization Risk: A Retrospective Cohort Study in a Large State Medicaid Program. Journal of General Internal Medicine 31:9, pages 1052-1060.
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Sadeen A. Adegbola, Gert J.O. Marincowitz, Indiran Govender & Gboyega A.O. Ogunbanjo. (2016) Assessment of self-reported adherence among patients with type 2 diabetes in Matlala District Hospital, Limpopo Province. African Journal of Primary Health Care & Family Medicine 8:1.
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Matthew J. CrowleyDavid EdelmanAnn T. McAndrewSusan KistlerSusanne DanusJason A. WebbJoseph ZangaLinda L. SandersCynthia J. CoffmanGeorge L. JacksonHayden B. Bosworth. (2016) Practical Telemedicine for Veterans with Persistently Poor Diabetes Control: A Randomized Pilot Trial. Telemedicine and e-Health 22:5, pages 376-384.
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D. A. Perwitasari & S. Urbayatun. (2016) Treatment Adherence and Quality of Life in Diabetes Mellitus Patients in Indonesia. SAGE Open 6:2, pages 215824401664374.
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Marcelo Katz & Hayden Barry Bosworth. (2016) Behavioral sciences in clinical practice. Einstein (São Paulo) 14:1, pages vii-xiv.
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Erin K. Buysman, Wing Chow, Henry J. Henk & Marcia F. T. Rupnow. (2015) Characteristics and outcomes of patients with type 2 diabetes mellitus treated with canagliflozin: a real-world analysis. BMC Endocrine Disorders 15:1.
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