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Review

Nail psoriasis: clinical features, pathogenesis, differential diagnoses, and management

Pages 51-63 | Published online: 16 Oct 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Alexander Egeberg, Lars Erik Kristensen, Luis Puig, Phoebe Rich, Saxon D. Smith, Alyssa Garrelts, Kyoungah See, Thorsten Holzkaemper, Konstantinos Fotiou & Christopher Schuster. (2023) Network meta-analyses comparing the efficacy of biologic treatments for achieving complete resolution of nail psoriasis at 24–28 and 48–52 weeks. Journal of Dermatological Treatment 34:1.
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Matilde Iorizzo & Antonella Tosti. (2023) Updates in treatment and impact of nail psoriasis. Expert Review of Clinical Immunology 19:9, pages 1091-1100.
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Debra K. Lee & Shari R. Lipner. (2022) Optimal diagnosis and management of common nail disorders. Annals of Medicine 54:1, pages 694-712.
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Kristian Reich, Curdin Conrad, Lars Erik Kristensen, Saxon D. Smith, Luis Puig, Phoebe Rich, Christophe Sapin, Thorsten Holzkaemper, Uffe Koppelhus & Christopher Schuster. (2022) Network meta-analysis comparing the efficacy of biologic treatments for achieving complete resolution of nail psoriasis. Journal of Dermatological Treatment 33:3, pages 1652-1660.
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Boni Elewski, Phoebe Rich, Edward Lain, Jennifer Soung, George Michael Lewitt & Abby Jacobson. (2022) Efficacy of brodalumab in the treatment of scalp and nail psoriasis: results from three phase 3 trials. Journal of Dermatological Treatment 33:1, pages 261-265.
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Shrook A. Khashaba, Hend Gamil, Reham Salah & Eman Salah. (2021) Efficacy of long-pulsed Nd-YAG laser in the treatment of nail psoriasis: a clinical and dermoscopic evaluation. Journal of Dermatological Treatment 32:4, pages 446-452.
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Mary Patricia Smith, Karen Ly, Quinn Thibodeaux, Tina Bhutani, Wilson Liao & Kristen M Beck. (2019) Acrodermatitis continua of Hallopeau: clinical perspectives. Psoriasis: Targets and Therapy 9, pages 65-72.
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Articles from other publishers (33)

Shiv Bahadur & Manisha Sharma. (2023) Liposome Based Drug Delivery for the Management of Psoriasis - A Comprehensive Review. Current Pharmaceutical Biotechnology 24:11, pages 1383-1396.
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Lourdes Navarro. (2023) Pattern diagnosis of onycholysis. JEADV Clinical Practice.
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Muazzez Çiğdem Oba, Çiğdem Dicle Arıcan & Fatih Göktay. (2023) Histopathological nail-clipping examination for the diagnosis of isolated childhood nail psoriasis: A case report. TURKDERM 57:1, pages 34-35.
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Alexis Trecourt, Meja Rabodonirina, Claire Mauduit, Alexandra Traverse-Glehen, Mojgan Devouassoux-Shisheboran, David Meyronet, Frédérique Dijoud, Christophe Ginevra, Emmanuelle Chapey-Picq, Emilie Josse, Patricia Martins-Simoes, Abderrazzak Bentaher, Damien Dupont, Charline Miossec, Florence Persat, Martine Wallon, Tristan Ferry, Félix Pham, Bruno Simon & Jean Menotti. (2023) Fungal Integrated Histomolecular Diagnosis Using Targeted Next-Generation Sequencing on Formalin-Fixed Paraffin-Embedded Tissues. Journal of Clinical Microbiology 61:3.
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Maha Adel Shaheen, Azzahra Omar Dakhli & Samah Ibrahim Hassen. (2023) Comparison between the efficacy of Intense Pulsed Light (I.P.L.) versus Photo-Dynamic Therapy (P.D.T.) with methylene-blue in the treatment of psoriatic nails. Photodiagnosis and Photodynamic Therapy 41, pages 103298.
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Ahu Yorulmaz. (2023) Dermoscopy: the ultimate tool for diagnosis of nail psoriasis? A review of the diagnostic utility of dermoscopy in nail psoriasis. Acta Dermatovenerologica Alpina Pannonica et Adriatica 32:1.
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Gizem Cengiz, Kemal Nas, Yaşar Keskin, Erkan Kılıç, Betül Sargin, Sevtap Acer Kasman, Hakan Alkan, Nilay Sahin, Nihan Cüzdan Balta, İlknur Albayrak Gezer, Dilek Keskin, Cevriye Mülkoğlu, Hatice Reşorlu, Şebnem Ataman, Ajda Bal, Merve Baykul, Mehmet Tuncay Duruöz, Okan Küçükakkaş, Ozan Volkan Yurdakul, Meltem Alkan Melikoğlu, Fikriye Figen Ayhan, Hatice Bodur, Mustafa Çaliş, Erhan Çapkin, Gül Devrimsel, Kevser Gök, Sami Hizmetli, Ayhan Kamanlı, Hilal Ecesoy, Öznur Kutluk, Nesrin Şen, Ömer Faruk Şendur, İbrahim Tekeoğlu, Murat Toprak, Sena Tolu & Tiraje Tuncer. (2022) The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross‐sectional multicenter study. International Journal of Rheumatic Diseases 26:1, pages 43-50.
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Alexander Egeberg, Lars Erik Kristensen, Ronald Vender, Shirin Zaheri, Celine El Baou, Gaia Gallo, Elisabeth Riedl & Christopher Schuster. (2022) Sustained Resolution of Nail Psoriasis Through 5 Years with Ixekizumab: A Post-Hoc analysis from UNCOVER-3. Acta Dermato-Venereologica 102, pages adv00787.
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Iman Mohamed Abdelmeniem, Iman Mohamed El Eryan, Ahmad Nofal, Ibrahim Fouda & Salma Samir Omar. (2022) Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5‐fluorouracil, and methotrexate in the treatment of nail psoriasis: A comparative study. Dermatologic Therapy 35:9.
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Vinzent Kevin Ortner, Victor Desmond Mandel, Serena Bertugno, Peter Alshede Philipsen & Merete Haedersdal. (2022) Imaging of the nail unit in psoriatic patients:A systematic scoping review of techniques and terminology. Experimental Dermatology 31:6, pages 828-840.
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O. V. Zhukova, S. I. Artemyeva & A.A.-H.M. Al-Hawatmi. (2022) Nail psoriasis: dynamics of the clinical course during anti-IL-17 therapy. Meditsinskiy sovet = Medical Council:3, pages 38-45.
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Matilde Iorizzo, Michela Starace & Marcel C. Pasch. (2022) Leukonychia: What Can White Nails Tell Us?. American Journal of Clinical Dermatology 23:2, pages 177-193.
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Ahu Yorulmaz & Gunes Gur Aksoy. (2022) Dermoscopic Features of Nail Psoriasis: Revisited. Skin Appendage Disorders 8:5, pages 389-398.
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Giovanni Damiani, Nicola Luigi Bragazzi, Chante Karimkhani Aksut, Dongze Wu, Gianfranco Alicandro, Dennis McGonagle, Cui Guo, Robert Dellavalle, Ayman Grada, Priscilla Wong, Carlo La Vecchia, Lai-Shan Tam, Kevin D. Cooper & Mohsen Naghavi. (2021) The Global, Regional, and National Burden of Psoriasis: Results and Insights From the Global Burden of Disease 2019 Study. Frontiers in Medicine 8.
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Christoph R. Löser, Pietro Nenoff, Oliver Mainusch, Edgar Dippel & Galina Balakirski. (2021) Häufige Nagelerkrankungen: Diagnostik und Therapie. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 19:12, pages 1761-1776.
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Christoph R. Löser, Pietro Nenoff, Oliver Mainusch, Edgar Dippel & Galina Balakirski. (2021) Common diseases of the nail: Diagnosis and therapy. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 19:12, pages 1761-1775.
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Pradhap K, Abhishek Abhinay & Sunil Kumar Rao. (2020) Blackening of Nails with Pits – A Combination of Nail Psoriasis and Onychomycosis. Indian Journal of Pediatrics 88:9, pages 933-934.
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FangYuan Long, ZhiQin Zhang, Fang He, Jie Tu, Zhi Yin, JiPing Xia, Yan Lu & ZhiQiang Yin. (2021) Dermoscopic features of nail psoriasis: Positive correlation with the severity of psoriasis. The Journal of Dermatology 48:6, pages 894-901.
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I‐Lun Tseng, Chao‐Chun Yang, Edward Chia‐Cheng Lai & Chaw‐Ning Lee. (2021) Psoriasis in the geriatric population: A retrospective study in Asians. The Journal of Dermatology 48:6, pages 818-824.
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Philip J. Mease, Mei Liu, Sabrina Rebello, Robert R. McLean, Blessing Dube, Meghan Glynn, Peter Hur & Alexis Ogdie. (2021) Association of Nail Psoriasis With Disease Activity Measures and Impact in Psoriatic Arthritis: Data From the Corrona Psoriatic Arthritis/Spondyloarthritis Registry. The Journal of Rheumatology 48:4, pages 520-526.
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Minsu Kim, Seungkeol Yang, Bo Ri Kim & Sang Woong Youn. (2020) Nail involvement features in palmoplantar pustulosis. The Journal of Dermatology 48:3, pages 360-365.
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Anca E. Chiriac, Doina Azoicai, Adina Coroaba, Florica Doroftei, Daniel Timpu, Anca Chiriac, Mihaela Pertea, Elena-Laura Ursu & Mariana Pinteala. (2021) Raman Spectroscopy, X-ray Diffraction, and Scanning Electron Microscopy as Noninvasive Methods for Microstructural Alterations in Psoriatic Nails. Molecules 26:2, pages 280.
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P. D. Yesudian & D. A. R. de Berker. (2020) Inflammatory nail conditions. Part 1: nail changes in psoriasis. Clinical and Experimental Dermatology 46:1, pages 9-15.
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L. Thomas, J. Azad & A. Takwale. (2020) Management of nail psoriasis. Clinical and Experimental Dermatology 46:1, pages 3-8.
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Selami Aykut Temiz, İlkay Özer, Arzu Ataseven, Recep Dursun & Mehmet Uyar. (2020) The effect of smoking on the psoriasis: Is it related to nail involvement?. Dermatologic Therapy 33:6.
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. (2020) Differential Diagnosis of Nail Psoriasis and Onychomycoses: A Report Based on 40 Years of Specialised Nail Consultations. EMJ Dermatology.
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Zohreh Tehranchinia, Nasibeh Barzkar, Seyed Mohammad Riahi & Marjan Khazan. (2020) A Comparison of The Effects of Clobetasol 0.05% and Photodynamic Therapy Using Aminolevulinic Acid With Red Light in the Treatment of Severe Nail Psoriasis. Journal of Lasers in Medical Sciences 11:1, pages 3-7.
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Wuyuntana Wang, Yuhai, Huan Wang, Chasuna & Bagenna. (2019) Astilbin reduces ROS accumulation and VEGF expression through Nrf2 in psoriasis-like skin disease. Biological Research 52:1.
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Marco Diani, Silvia Perego, Veronica Sansoni, Lucrezia Bertino, Marta Gomarasca, Martina Faraldi, Paolo Daniele Maria Pigatto, Giovanni Damiani, Giuseppe Banfi, Gianfranco Altomare & Giovanni Lombardi. (2019) Differences in Osteoimmunological Biomarkers Predictive of Psoriatic Arthritis among a Large Italian Cohort of Psoriatic Patients. International Journal of Molecular Sciences 20:22, pages 5617.
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Vincent A. Pallazola, Gerard Deib, Soni Abha, Rabih M. Geha & Kimiyoshi Kobayashi. (2019) An Elusive Case of Mycosis Fungoides: Case Report and Review of the Literature. Journal of General Internal Medicine 34:11, pages 2669-2674.
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Yesim Akpinar Kara. 2019. Tailored Treatments in Psoriatic Patients. Tailored Treatments in Psoriatic Patients.
Theresa N. Canavan, Lauren V. Graham & Boni E. Elewski. (2019) Subungual Space: The Next Frontier. Skin Appendage Disorders 5:1, pages 50-51.
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A. V. Platonova, A. S. Zhukov, V. R. Khairutdinov & A. V. Samtsov. (2018) Psoriatic onychodystrophy: clinical manifestations (part 1). Vestnik dermatologii i venerologii 94:6, pages 7-14.
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