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Reviews

The role for N-acetylcysteine in the management of COPD

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Pages 99-106 | Published online: 20 Oct 2022

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Natália Pereira da Silva Araújo, Natália Alves de Matos, Suianne Leticia Antunes Mota, Ana Beatriz Farias de Souza, Sílvia Dantas Cangussú, Rodrigo Cunha Alvim de Menezes & Frank Silva Bezerra. (2020) Quercetin Attenuates Acute Lung Injury Caused by Cigarette Smoke Both In Vitro and In Vivo. COPD: Journal of Chronic Obstructive Pulmonary Disease 17:2, pages 205-214.
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Alessandro Minarini, Silvia Ferrari, Martina Galletti, Nina Giambalvo, Daniela Perrone, Giulia Rioli & Gian Maria Galeazzi. (2017) N-acetylcysteine in the treatment of psychiatric disorders: current status and future prospects. Expert Opinion on Drug Metabolism & Toxicology 13:3, pages 279-292.
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Liu-Sheng Wang, Yang Hu, Chun-Lin Li, Yan Li, Ya-Ru Wei, Zhao-Fang Yin, Yu-Kui Du, Zhen Min, Dong Weng, Jian-Min Chen & Hui-Ping Li. (2015) N-acetylcysteine attenuates cigaret smoke-induced pulmonary exacerbation in a mouse model of emphysema. Inhalation Toxicology 27:14, pages 802-809.
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Wolfgang Domej, Karl Oettl & Wilfried Renner. (2014) Oxidative stress and free radicals in COPD – implications and relevance for treatment. International Journal of Chronic Obstructive Pulmonary Disease 9, pages 1207-1224.
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Jan De Backer, Wim Vos, Cedric Van Holsbeke, Samir Vinchurkar, Rita Claes, Paul M Parizel & Wilfried De Backer. (2013) Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients. International Journal of Chronic Obstructive Pulmonary Disease 8, pages 569-579.
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A Boutten, D Goven, J Boczkowski & M Bonay. (2010) Oxidative stress targets in pulmonary emphysema: focus on the Nrf2 pathway. Expert Opinion on Therapeutic Targets 14:3, pages 329-346.
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Articles from other publishers (9)

Hamad Ghaleb Dailah. (2022) Therapeutic Potential of Small Molecules Targeting Oxidative Stress in the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comprehensive Review. Molecules 27:17, pages 5542.
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Evangelia Eirini Tsermpini, Una Glamočlija, Fulden Ulucan-Karnak, Sara Redenšek Trampuž & Vita Dolžan. (2022) Molecular Mechanisms Related to Responses to Oxidative Stress and Antioxidative Therapies in COVID-19: A Systematic Review. Antioxidants 11:8, pages 1609.
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Marcos Martinez-Banaclocha. (2022) N-Acetyl-Cysteine: Modulating the Cysteine Redox Proteome in Neurodegenerative Diseases. Antioxidants 11:2, pages 416.
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Victoria Mutua & Laurel J. Gershwin. (2020) A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics. Clinical Reviews in Allergy & Immunology 61:2, pages 194-211.
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Sarah de Oliveira Rodrigues, Carolina Medina Coeli da Cunha, Giovanna Martins Valladão Soares, Pedro Leme Silva, Adriana Ribeiro Silva & Cassiano Felippe Gonçalves-de-Albuquerque. (2021) Mechanisms, Pathophysiology and Currently Proposed Treatments of Chronic Obstructive Pulmonary Disease. Pharmaceuticals 14:10, pages 979.
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Mylarappa Ningappa, Morayooluwa Adenuga, Kim A. Ngo, Nada Mohamed, Tejaswini Narayanan, Krishna Prasadan, Chethan Ashokkumar, Jishnu Das, Lori Schmitt, Hannah Hartman, Anuradha Sehrawat, Claudia M. Salgado, Miguel Reyes-Mugica, George K. Gittes, Cecilia W. Lo, Shankar Subramaniam & Rakesh Sindhi. (2021) Mechanisms of Impaired Lung Development and Ciliation in Mannosidase-1-Alpha-2 (Man1a2) Mutants. Frontiers in Physiology 12.
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Madeeha Nasir, Daniel Trujillo, Jessica Levine, Jennifer B. Dwyer, Zachary W. Rupp & Michael H. Bloch. (2020) Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA Psychopharmacology. Frontiers in Psychiatry 11.
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Rokhsara Rafii, Timothy E. Albertson, Samuel Louie & Andrew L. Chan. (2011) Update on Pharmaceutical and Minimally Invasive Management Strategies for Chronic Obstructive Pulmonary Disease. Pulmonary Medicine 2011, pages 1-11.
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Umesh C. S. Yadav, Amarjit S. Naura, Leopoldo Aguilera-Aguirre, Kota V. Ramana, Istvan Boldogh, Sanjiv Sur, Hamid A. Boulares & Satish K. Srivastava. (2009) Aldose Reductase Inhibition Suppresses the Expression of Th2 Cytokines and Airway Inflammation in Ovalbumin-Induced Asthma in Mice. The Journal of Immunology 183:7, pages 4723-4732.
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