Citations (123)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Jianghong Wu, Ziwen Long, Hong Cai, Shengjia Yu & Xiaowen Liu. (2019) Homeobox B7 accelerates the cancer progression of gastric carcinoma cells by promoting epithelial–mesenchymal transition (EMT) and activating Src–FAK pathway. OncoTargets and Therapy 12, pages 3743-3751.
Read now
Read now
Sunaho Okada, Sadaf A. Raja, Jonathan Okerblom, Aayush Boddu, Yousuke Horikawa, Supriyo Ray, Hideshi Okada, Itta Kawamura, Yoshiteru Murofushi, Fiona Murray & Hemal H. Patel. (2019) Deletion of caveolin scaffolding domain alters cancer cell migration. Cell Cycle 18:11, pages 1268-1280.
Read now
Read now
Peifen Lu, Junjun Chen, Lihong Yan, Lijun Yang, Litao Zhang, Jie Dai, Zixuan Hao, Tao Bai, Yanfeng Xi, Yahui Li, Zhiming Kang, Jun Xv, Gongqin Sun & Tao Yang. (2019) RasGRF2 promotes migration and invasion of colorectal cancer cells by modulating expression of MMP9 through Src/Akt/NF-κB pathway. Cancer Biology & Therapy 20:4, pages 435-443.
Read now
Read now
Cong-Hui Zhang, Jun-Xia Wang, Mei-Lian Cai, Rongguang Shao, Hong Liu & Wu-Li Zhao. (2019) The roles and mechanisms of G3BP1 in tumour promotion. Journal of Drug Targeting 27:3, pages 300-305.
Read now
Read now
SubbaRao V. Madhunapantula & Gavin P. Robertson. (2017) Targeting protein kinase-b3 (akt3) signaling in melanoma. Expert Opinion on Therapeutic Targets 21:3, pages 273-290.
Read now
Read now
Andrew M Handorf, Yaxian Zhou, Matthew A Halanski & Wan-Ju Li. (2015) Tissue Stiffness Dictates Development, Homeostasis, and Disease Progression. Organogenesis 11:1, pages 1-15.
Read now
Read now
Stephen YT Li, Dolores D Mruk & C Yan Cheng. (2013) Focal adhesion kinase is a regulator of F-actin dynamics. Spermatogenesis 3:3.
Read now
Read now
Kenzo Sonoda. (2012) RCAS1 is a promising therapeutic target against cancer: its multifunctional bioactivities and clinical significance. Expert Review of Obstetrics & Gynecology 7:3, pages 261-267.
Read now
Read now
Michelle K.Y. Siu, Ching Hang Wong, Weiliang Xia, Dolores D. Mruk, Will M. Lee & C. Yan Cheng. (2011) The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes. Spermatogenesis 1:1, pages 73-86.
Read now
Read now
Articles from other publishers (114)
Kang Wang, Dongsheng Wen, Xuewen Xu, Rui Zhao, Feipeng Jiang, Shengqin Yuan, Yifan Zhang, Ya Gao & Qingfeng Li. (2023) Extracellular matrix stiffness—The central cue for skin fibrosis. Frontiers in Molecular Biosciences 10.
Crossref
Crossref
Tingting Chen, Juan Wang, Min Li, Qingqing Wu & Shuna Cui. (2023) Genistein Inhibits Proliferation and Metastasis in Human Cervical Cancer Cells through the Focal Adhesion Kinase Signaling Pathway: A Network Pharmacology-Based In Vitro Study in HeLa Cells. Molecules 28:4, pages 1919.
Crossref
Crossref
Yueqing Xue, Liangyu Lin, Qing Li, Keli Liu, Mingyuan Hu, Jiayin Ye, Jianchang Cao, Jingjie Zhai, Fanjun Zheng, Yu Wang, Tao Zhang, Liming Du, Cheng Gao, Guan Wang, Xuefeng Wang, Jun Qin, Xinhua Liao, Xiangyin Kong, Lydia Sorokin, Yufang Shi & Ying Wang. (2022) SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes. Advanced Science 10:4, pages 2201949.
Crossref
Crossref
Khashayar Mozaffari, Mahlet Mekonnen, Maya Harary, Meachelle Lum, Brian Aguirre, Anubhav Chandla, Madhuri Wadehra & Isaac Yang. (2023) Epithelial membrane protein 2 (EMP2): A systematic review of its implications in pathogenesis. Acta Histochemica 125:1, pages 151976.
Crossref
Crossref
Zhiwei Qin & Chongzhi Zhou. (2022) HOXA13 promotes gastric cancer progression partially via the FN1-mediated FAK/Src axis. Experimental Hematology & Oncology 11:1.
Crossref
Crossref
Stefan Lennard Krautschneider, Fabian M. Troschel, Eduardo Vadillo, Hans Theodor Eich, Martin Götte, Nancy Adriana Espinoza-Sánchez & Burkhard Greve. (2022) Enzymatic Digestion of Cell-surface Heparan Sulfate Alters the Radiation Response in Triple-negative Breast Cancer Cells. Archives of Medical Research 53:8, pages 826-839.
Crossref
Crossref
Ana Carolina Silveira Rabelo, Maria Angélica Miglino, Shirley Arbizu, Ana Cláudia O. Carreira, Antônio José Cantanhede Filho, Fernando José Costa Carneiro, Marjorie Anne A. Layosa & Giuliana Noratto. (2022) Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR
Signaling in 4T1 Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry 22:18, pages 3136-3147.
Crossref
Crossref
Mengyuan Zhang, Xiaohang Chen, Yuan Zhang, Xiangyu Zhao, Jing Zhao & Xing Wang. (2022) The potential of functionalized dressing releasing flavonoids facilitates scar-free healing. Frontiers in Medicine 9.
Crossref
Crossref
Qianqian Wang, Dongyang Jiang, Qing Ye, Wenjing Zhou, Junfan Ma, Chong Wang, Zihan Geng, Ming Chu, Jie Zheng, Hongchengcheng Chen, Jing Huang, Hui Dai, Youhui Zhang, Zhanlong Shen, Ning Fu & Xiaoyan Qiu. (2022) A widely expressed free immunoglobulin κ chain with a unique Vκ4-1/Jκ3 pattern promotes colon cancer invasion and metastasis by activating the integrin β1/FAK pathway. Cancer Letters 540, pages 215720.
Crossref
Crossref
Austin J. Scholp, Jordan Jensen, Sathivel Chinnathambi, Keerthi Atluri, Alyssa Mendenhall, Timothy Fowler, Aliasger K. Salem, James A. Martin & Edward A. Sander. (2022) Force-Bioreactor for Assessing Pharmacological Therapies for Mechanobiological Targets. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Crossref
Yulia Kirdeeva, Olga Fedorova, Alexandra Daks, Nikolai Barlev & Oleg Shuvalov. (2022) How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?. Pharmaceuticals 15:7, pages 868.
Crossref
Crossref
Fangting Zhou, Kejun He, James J. Cai, Laurie A. Davidson, Robert S. Chapkin & Yang Ni. (2022) A Unified Bayesian Framework for Bi-overlapping-Clustering Multi-omics Data via Sparse Matrix Factorization. Statistics in Biosciences.
Crossref
Crossref
Greta Mucignat, Irene Bassan, Mery Giantin, Marianna Pauletto, Anisa Bardhi, Silvia Iori, Rosa Maria Lopparelli, Andrea Barbarossa, Anna Zaghini, Enrico Novelli & Mauro Dacasto. (2022) Does Bentonite Cause Cytotoxic and Whole-Transcriptomic Adverse Effects in Enterocytes When Used to Reduce Aflatoxin B1 Exposure?. Toxins 14:7, pages 435.
Crossref
Crossref
Shu-Chen Chu, Yih-Shou Hsieh, Li-Sung Hsu, Chin-Yin Lin, Yi-An Lai & Pei-Ni Chen. (2022) Cinnamaldehyde decreases the invasion and u-PA expression of osteosarcoma by down-regulating the FAK signalling pathway. Food & Function 13:12, pages 6574-6582.
Crossref
Crossref
Chin-Lin Guo. (2022) Self-Sustained Regulation or Self-Perpetuating Dysregulation: ROS-dependent HIF-YAP-Notch Signaling as a Double-Edged Sword on Stem Cell Physiology and Tumorigenesis. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Changhuo Cen, Fengyue Wang, Keyi Xiong, Lin Jiang & Xiaohui Hou. (2021)
Protective effects of
Coridius chinensis
extracts on rat reproductive damage induced by manganese
. Andrologia 54:2.
Crossref
Crossref
HyacinthN Highland, MonicaB Thakur & Linz-Buoy George. (2022) Controlling non small cell lung cancer progression by blocking focal adhesion kinase-c-Src active site with Rosmarinus officinalis L. phytocomponents: An in silico and in vitro study. Journal of Cancer Research and Therapeutics 18:6, pages 1674.
Crossref
Crossref
Putthaporn Kaewmeesri, Piman Pocasap, Veerapol Kukongviriyapan, Auemduan Prawan, Sarinya Kongpetch & Laddawan Senggunprai. (2022) Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integrative Cancer Therapies 21, pages 153473542211248.
Crossref
Crossref
Bar Levi, Shiri Yacobovich, Michael Kirby, Maria Becker, Oryan Agranyoni, Boris Redko, Gary Gellerman, Albert Pinhasov, Igor Koman & Elimelech Nesher. (2021) Anti-Cancer Effects of Cyclic Peptide ALOS4 in a Human Melanoma Mouse Model. International Journal of Molecular Sciences 22:17, pages 9579.
Crossref
Crossref
Yasaswi Gayatri Mishra & Bramanandam Manavathi. (2021) Focal adhesion dynamics in cellular function and disease. Cellular Signalling 85, pages 110046.
Crossref
Crossref
Hanna Cho, Injae Shin, Hojong Yoon, Eunhye Jeon, Jiwon Lee, Younghoon Kim, SeongShick Ryu, Chiman Song, Nam Hoon Kwon, Youngji Moon, Sunghoon Kim, Nam Doo Kim, Hwan Geun Choi & Taebo Sim. (2021)
Identification of Thieno[3,2-
d
]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3
. Journal of Medicinal Chemistry 64:16, pages 11934-11957.
Crossref
Crossref
Hina Mir, Neeraj Kapur, Dominique N. Gales, Praveen K. Sharma, Gabriela Oprea-Ilies, Anita T. Johnson, Rajesh Singh & Shailesh Singh. (2021) CXCR6-CXCL16 Axis Promotes Breast Cancer by Inducing Oncogenic Signaling. Cancers 13:14, pages 3568.
Crossref
Crossref
Nicolas S Merle, Parul Singh, Jubayer Rahman & Claudia Kemper. (2020) Integrins meet complement: The evolutionary tip of an iceberg orchestrating metabolism and immunity. British Journal of Pharmacology 178:14, pages 2754-2770.
Crossref
Crossref
Ragini Yeeravalli, Komal Kaushik & Amitava Das. (2021) TWIST1-mediated transcriptional activation of PDGFRβ in breast cancer stem cells promotes tumorigenesis and metastasis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:7, pages 166141.
Crossref
Crossref
Chiung-Chi Cheng, Wei-Ting Chao, Jing-Hao Shih, Yih-Shyong Lai, Yung-Hsiang Hsu & Yi-Hsiang Liu. (2021) Sorafenib combined with dasatinib therapy inhibits cell viability, migration, and angiogenesis synergistically in hepatocellular carcinoma. Cancer Chemotherapy and Pharmacology 88:1, pages 143-153.
Crossref
Crossref
Xinxin Cheng, Jie Wang, Chunling Liu, Tianduo Jiang, Ningzhi Yang, Dan Liu, Huanhuan Zhao & Zhelong Xu. (2021) Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway. Journal of Experimental & Clinical Cancer Research 40:1.
Crossref
Crossref
Makhdoom Sarwar, Peter H. Sykes, Kenny Chitcholtan & John J. Evans. (2021) Deciphering Biophysical Modulation in Ovarian Cancer Cells. Cell Biochemistry and Biophysics 79:2, pages 375-386.
Crossref
Crossref
Nehal Gupta & Sanjay K. Srivastava. (2021) Atovaquone Suppresses the Growth of Metastatic Triple-Negative Breast Tumors in Lungs and Brain by Inhibiting Integrin/FAK Signaling Axis. Pharmaceuticals 14:6, pages 521.
Crossref
Crossref
Christine E. Lehman, Adam Spencer, Sarah Hall, Jeremy J. P. Shaw, Julia Wulfkuhle, Emanuel F. Petricoin, Stefan Bekiranov, Mark J. Jameson & Daniel Gioeli. (2021) IGF1R and Src inhibition induce synergistic cytotoxicity in HNSCC through inhibition of FAK. Scientific Reports 11:1.
Crossref
Crossref
Afshin Derakhshani, Zeinab Rostami, Hossein Safarpour, Mahdi Abdoli Shadbad, Niloufar Sadat Nourbakhsh, Antonella Argentiero, Sina Taefehshokr, Neda Jalili Tabrizi, Omid Kooshkaki, Reza Vaezi Astamal, Pankaj Kumar Singh, Nima Taefehshokr, Nazila Alizadeh, Nicola Silvestris & Behzad Baradaran. (2021) From Oncogenic Signaling Pathways to Single-Cell Sequencing of Immune Cells: Changing the Landscape of Cancer Immunotherapy. Molecules 26:8, pages 2278.
Crossref
Crossref
Joselina Magali Mondaca, Ana Carla Castro Guijarro, Marina Inés Flamini & Angel Matias Sanchez. (2021) Heregulin-induced cell migration is prevented by trastuzumab and trastuzumab-emtansine in HER2+ breast cancer. Breast Cancer Research and Treatment 186:2, pages 363-377.
Crossref
Crossref
Yih-Shou Hsieh, Shu-Chen Chu, Shih-Chien Huang, Shao-Hsuan Kao, Meng-Shuan Lin & Pei-Ni Chen. (2020) Gossypol Reduces Metastasis and Epithelial-Mesenchymal Transition by Targeting Protease in Human Cervical Cancer. The American Journal of Chinese Medicine 49:01, pages 181-198.
Crossref
Crossref
G. K. Rystsov, T. V. Antipova, K. V. Zaitsev & M. Yu. Zemskova. (2021) Antitumor Activity of Monasnicotinic Acid Isolated from the Fungus Aspergillus cavernicola. Russian Journal of Bioorganic Chemistry 47:1, pages 307-316.
Crossref
Crossref
Ting Wang, Haojie Jin, Jingying Hu, Xi Li, Haoyu Ruan, Huili Xu, Lin Wei, Weihua Dong, Fei Teng, Jianren Gu, Wenxin Qin, Xiaoying Luo & Yujun Hao. (2020) COL4A1 promotes the growth and metastasis of hepatocellular carcinoma cells by activating FAK-Src signaling. Journal of Experimental & Clinical Cancer Research 39:1.
Crossref
Crossref
Filippo Torrisi, Nunzio Vicario, Federica M. Spitale, Francesco P. Cammarata, Luigi Minafra, Lucia Salvatorelli, Giorgio Russo, Giacomo Cuttone, Samuel Valable, Rosario Gulino, Gaetano Magro & Rosalba Parenti. (2020) The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance. Cancers 12:10, pages 2860.
Crossref
Crossref
Yara A. Lobo, Camila Bonazza, Fabrício P. Batista, Rodrigo A. Castro, Camila R. Bonturi, Bruno R. Salu, Rita de Cassia Sinigaglia, Leny Toma, Carolina M. Vicente, Giselle Pidde, Denise V. Tambourgi, Miryam P. Alvarez-Flores, Ana M. Chudzinski-Tavassi & Maria Luiza V. Oliva. (2020) EcTI impairs survival and proliferation pathways in triple-negative breast cancer by modulating cell-glycosaminoglycans and inflammatory cytokines. Cancer Letters 491, pages 108-120.
Crossref
Crossref
Gianluca Selvaggio, Sara Canato, Archana Pawar, Pedro T. Monteiro, Patrícia S. Guerreiro, M. Manuela Brás, Florence Janody & Claudine Chaouiya. (2020) Hybrid Epithelial–Mesenchymal Phenotypes Are Controlled by Microenvironmental Factors. Cancer Research 80:11, pages 2407-2420.
Crossref
Crossref
Ozge Saatci, Aysegul Kaymak, Umar Raza, Pelin G. Ersan, Ozge Akbulut, Carolyn E. Banister, Vitali Sikirzhytski, Unal Metin Tokat, Gamze Aykut, Suhail A. Ansari, Hayriye Tatli Dogan, Mehmet Dogan, Pouria Jandaghi, Aynur Isik, Fatma Gundogdu, Kemal Kosemehmetoglu, Omer Dizdar, Sercan Aksoy, Aytekin Akyol, Aysegul Uner, Phillip J. Buckhaults, Yasser Riazalhosseini & Ozgur Sahin. (2020) Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer. Nature Communications 11:1.
Crossref
Crossref
Kinga B. Stopa, Agnieszka A. Kusiak, Mateusz D. Szopa, Pawel E. Ferdek & Monika A. Jakubowska. (2020) Pancreatic Cancer and Its Microenvironment—Recent Advances and Current Controversies. International Journal of Molecular Sciences 21:9, pages 3218.
Crossref
Crossref
Bijiao Zhou, Shumin Zong, Weilong Zhong, Yixuan Tian, Lumeng Wang, Qian Zhang, Renya Zhang, Lei Li, Wei Wang, Jianmin Zhao, Xin Chen, Yaju Feng, Binghui Zhai, Tao Sun & Yanrong Liu. (2019) Interaction between laminin-5γ2 and integrin β1 promotes the tumor budding of colorectal cancer via the activation of Yes-associated proteins. Oncogene 39:7, pages 1527-1542.
Crossref
Crossref
Michalina Janiszewska, Marina Candido Primi & Tina Izard. (2020) Cell adhesion in cancer: Beyond the migration of single cells. Journal of Biological Chemistry 295:8, pages 2495-2505.
Crossref
Crossref
Caihong Wang, Shaosen Zhang, Jie Liu, Yang Tian, Boyuan Ma, Siran Xu, Yan Fu & Yongzhang Luo. (2020) Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway. Cell Reports 30:6, pages 1780-1797.e6.
Crossref
Crossref
Suyash Srivastava, Fatema Tuz Zahra, Nehal Gupta, Paul E. Tullar, Sanjay K. Srivastava & Constantinos M. Mikelis. (2020) Low Dose of Penfluridol Inhibits VEGF-Induced Angiogenesis. International Journal of Molecular Sciences 21:3, pages 755.
Crossref
Crossref
Kazuo Katoh. (2020) FAK-Dependent Cell Motility and Cell Elongation. Cells 9:1, pages 192.
Crossref
Crossref
Wuttipong Masraksa, Supita Tanasawet, Pilaiwanwadee Hutamekalin, Tulaporn Wongtawatchai & Wanida Sukketsiri. (2020) Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway. Nutrition Research and Practice 14:2, pages 127.
Crossref
Crossref
Praveen Bhoopathi, Anjan K. Pradhan, Manny D. Bacolod, Luni Emdad, Devanand Sarkar, Swadesh K. Das & Paul B. Fisher. (2019) Regulation of neuroblastoma migration, invasion, and in vivo metastasis by genetic and pharmacological manipulation of MDA-9/Syntenin. Oncogene 38:41, pages 6781-6793.
Crossref
Crossref
Abdulaziz Asiri, Michael S. Toss, Teresa Pereira Raposo, Maham Akhlaq, Hannah Thorpe, Abdulaziz Alfahed, Abutaleb Asiri & Mohammad Ilyas. (2019) Cten promotes Epithelial–Mesenchymal Transition (EMT) in colorectal cancer through stabilisation of Src. Pathology International 69:7, pages 381-391.
Crossref
Crossref
Arslaan Javaeed & Sanniya Khan Ghauri. (2019) Metastatic potential and prognostic significance of SOX2: A meta-analysis. World Journal of Clinical Oncology 10:6, pages 234-246.
Crossref
Crossref
Leon J. DeLalio, Marie Billaud, Claire A. Ruddiman, Scott R. Johnstone, Joshua T. Butcher, Abigail G. Wolpe, Xueyao Jin, T.C. Stevenson KellerIVIV, Alexander S. Keller, Thibaud Rivière, Miranda E. Good, Angela K. Best, Alexander W. Lohman, Leigh Anne Swayne, Silvia Penuela, Roger J. Thompson, Paul D. Lampe, Mark Yeager & Brant E. Isakson. (2019) Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane. Journal of Biological Chemistry 294:17, pages 6940-6956.
Crossref
Crossref
Brittelle E. Kessler, Katie M. Mishall, Meghan D. Kellett, Erin G. Clark, Umarani Pugazhenthi, Nikita Pozdeyev, Jihye Kim, Aik Choon Tan & Rebecca E. Schweppe. (2018) Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis. Oncogene 38:14, pages 2565-2579.
Crossref
Crossref
Amita M Vaidya, Zhanhu Sun, Nadia Ayat, Andrew Schilb, Xujie Liu, Hongfa Jiang, Da Sun, Josef Scheidt, Victoria Qian, Siyuan He, Hannah Gilmore, William P. Schiemann & Zheng-Rong Lu. (2019) Systemic Delivery of Tumor-Targeting siRNA Nanoparticles against an Oncogenic LncRNA Facilitates Effective Triple-Negative Breast Cancer Therapy. Bioconjugate Chemistry 30:3, pages 907-919.
Crossref
Crossref
Keun-Yeong Jeong. (2018) Inhibiting focal adhesion kinase: A potential target for enhancing therapeutic efficacy in colorectal cancer therapy. World Journal of Gastrointestinal Oncology 10:10, pages 290-292.
Crossref
Crossref
Subbroto Saha, Kyeongseok Kim, Gwang-Mo Yang, Hye Choi & Ssang-Goo Cho. (2018) Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells. International Journal of Molecular Sciences 19:5, pages 1423.
Crossref
Crossref
Vasiliki Gkretsi & Triantafyllos Stylianopoulos. (2018) Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis. Frontiers in Oncology 8.
Crossref
Crossref
Hitendra S. Solanki, Remya Raja, Alex Zhavoronkov, Ivan V. Ozerov, Artem V. Artemov, Jayshree Advani, Aneesha Radhakrishnan, Niraj Babu, Vinuth N. Puttamallesh, Nazia Syed, Vishalakshi Nanjappa, Tejaswini Subbannayya, Nandini A. Sahasrabuddhe, Arun H. Patil, T.S. Keshava Prasad, Daria Gaykalova, Xiaofei Chang, Rachana Sathyendran, Premendu Prakash Mathur, Annapoorni Rangarajan, David Sidransky, Akhilesh Pandey, Evgeny Izumchenko, Harsha Gowda & Aditi Chatterjee. (2018) Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor. Oncoscience 5:1-2, pages 21-38.
Crossref
Crossref
Renzhong Li, Tony Wang, Khyati Walia, Bo Gao & Joan C. Krepinsky. (2018) ADAM17 activation and regulation of profibrotic responses by high glucose requires its C-terminus and FAK kinase. Journal of Cell Science.
Crossref
Crossref
Seul Lee, Jin Kim, Han-Saem Lee, Yu-Mi Lim, Jai-Hyun So, Dongyup Hahn, Yu Ha & Ju-Ock Nam. (2017) Bioconverted Orostachys japonicas Extracts Suppress Angiogenic Activity of Ms-1 Endothelial Cells. International Journal of Molecular Sciences 18:12, pages 2615.
Crossref
Crossref
Marisa A. Fuse, Stephani Klingeman Plati, Sarah S. Burns, Christine T. Dinh, Olena Bracho, Denise Yan, Rahul Mittal, Rulong Shen, Julia N. Soulakova, Alicja J. Copik, Xue Zhong Liu, Fred F. Telischi, Long-Sheng Chang, Maria Clara Franco & Cristina Fernandez-Valle. (2017) Combination Therapy with c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells. Molecular Cancer Therapeutics 16:11, pages 2387-2398.
Crossref
Crossref
Jhang Ho Pak, Qudsia Bashir, In Ki Kim, Sung-Jong Hong, Sejung Maeng, Young Yil Bahk & Tong-Soo Kim. (2017) Clonorchis sinensis excretory-secretory products promote the migration and invasion of cholangiocarcinoma cells by activating the integrin β4–FAK/Src signaling pathway. Molecular and Biochemical Parasitology 214, pages 1-9.
Crossref
Crossref
Yi-Wen Huang, Chun-Yi Chuang, Yih-Shou Hsieh, Pei-Ni Chen, Shun-Fa Yang, Shih-Hsuan-Lin, Yang-Yu Chen, Chiao-Wen Lin & Yu-Chao Chang. (2017)
Rubus idaeus
extract suppresses migration and invasion of human oral cancer by inhibiting MMP-2 through modulation of the Erk1/2 signaling pathway
. Environmental Toxicology 32:3, pages 1037-1046.
Crossref
Crossref
Yandong Nan, Jie Du, Lijie Ma, Hua Jiang, Faguang Jin & Shuanying Yang. (2016) Early Candidate Biomarkers of Non–Small Cell Lung Cancer Are Screened and Identified in Premalignant Lung Lesions. Technology in Cancer Research & Treatment 16:1, pages 66-74.
Crossref
Crossref
Marina Inés Flamini, Ivonne Denise Uzair, Gisela Erika Pennacchio, Flavia Judith Neira, Joselina Magali Mondaca, Fernando Dario Cuello-Carrión, Graciela Alma Jahn, Tommaso Simoncini & Angel Matías Sanchez. (2017) Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin αV/β3/SRC/FAK/PI3-Kinases. Hormones and Cancer 8:1, pages 16-27.
Crossref
Crossref
C-H Chen, W-H Chang, K-Y Su, W-H Ku, G-C Chang, Q-S Hong, Y-J Hsiao, H-C Chen, H-Y Chen, R Wu, P-C Yang, J J W Chen & S-L Yu. (2016) HLJ1 is an endogenous Src inhibitor suppressing cancer progression through dual mechanisms. Oncogene 35:43, pages 5674-5685.
Crossref
Crossref
Jin-Ah Kim, Ying Tan, Xian Wang, Xixi Cao, Jamunarani Veeraraghavan, Yulong Liang, Dean P. Edwards, Shixia Huang, Xuewen Pan, Kaiyi Li, Rachel Schiff & Xiao-Song Wang. (2016) Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers. Nature Communications 7:1.
Crossref
Crossref
Brittelle E. Kessler, Vibha Sharma, Qiong Zhou, Xia Jing, Laura A. Pike, Anna A. Kerege, Sharon B. Sams & Rebecca E. Schweppe. (2016) FAK Expression, Not Kinase Activity, Is a Key Mediator of Thyroid Tumorigenesis and Protumorigenic Processes. Molecular Cancer Research 14:9, pages 869-882.
Crossref
Crossref
Bridget T. Kreger, Andrew L. Dougherty, Kai Su Greene, Richard A. Cerione & Marc A. Antonyak. (2016) Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation. Journal of Biological Chemistry 291:38, pages 19774-19785.
Crossref
Crossref
Elena Porcù, Luca Persano, Roberto Ronca, Stefania Mitola, Roberta Bortolozzi, Romeo Romagnoli, Paola Oliva, Giuseppe Basso & Giampietro Viola. (2016) The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation. Scientific Reports 6:1.
Crossref
Crossref
Tung-Yi Lin & Hsien-Yeh Hsu. (2016) Ling Zhi-8 reduces lung cancer mobility and metastasis through disruption of focal adhesion and induction of MDM2-mediated Slug degradation. Cancer Letters 375:2, pages 340-348.
Crossref
Crossref
Linlin Su, Xiaodong Li, Xue Wu, Bo Hui, Shichao Han, Jianxin Gao, Yan Li, Jihong Shi, Huayu Zhu, Bin Zhao & Dahai Hu. (2016) Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar. Scientific Reports 6:1.
Crossref
Crossref
Qingyu Zhou, Lunawati L Bennett & Shufeng Zhou. (2016) Multifaceted ability of naturally occurring polyphenols against metastatic cancer. Clinical and Experimental Pharmacology and Physiology 43:4, pages 394-409.
Crossref
Crossref
Hinke A.B. Multhaupt, Birgit Leitinger, Donald Gullberg & John R. Couchman. (2016) Extracellular matrix component signaling in cancer. Advanced Drug Delivery Reviews 97, pages 28-40.
Crossref
Crossref
Akter Khondker Ayesha, Toshinori Hyodo, Eri Asano, Naoki Sato, Mohammed A. Mansour, Satoko Ito, Michinari Hamaguchi & Takeshi Senga. (2015) UBE2S is associated with malignant characteristics of breast cancer cells. Tumor Biology 37:1, pages 763-772.
Crossref
Crossref
Karma Z. Salem, Michele Moschetta, Antonio Sacco, Luisa Imberti, Giuseppe Rossi, Irene M. Ghobrial, Salomon Manier & Aldo M. Roccaro. 2016. Tumor Angiogenesis Assays. Tumor Angiogenesis Assays
25
34
.
Masato Kobayashi, Shiori Kuroki, Yu Tanaka, Yukari Moriya, Yukari Kozutumi, Yuji Uehara, Kenichiro Ono, Kyoichi Tamura, Tsukimi Washizu & Makoto Bonkobara. (2015)
Molecular changes associated with the development of resistance to imatinib in an imatinib-sensitive canine neoplastic mast cell line carrying a
KIT
c.1523A>T mutation
. European Journal of Haematology 95:6, pages 524-531.
Crossref
Crossref
RAN ZHAO, YIQI WU, TIANZHEN WANG, YUHUA ZHANG, DAN KONG, LEI ZHANG, XIAOBO LI, GUANGYU WANG, YINJI JIN, XIAOMING JIN & FENGMIN ZHANG. (2015) Elevated Src expression associated with hepatocellular carcinoma metastasis in northern Chinese patients. Oncology Letters 10:5, pages 3026-3034.
Crossref
Crossref
Maria A. Missinato, Kimimasa Tobita, Nicla Romano, James A. Carroll & Michael Tsang. (2015) Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration. Cardiovascular Research 107:4, pages 487-498.
Crossref
Crossref
Y W Moon, G Rao, J J Kim, H-S Shim, K-S Park, S S An, B Kim, P S Steeg, S Sarfaraz, L Changwoo Lee, Donna Voeller, E Y Choi, Ji Luo, D Palmieri, H C Chung, J-H Kim, Y Wang & G Giaccone. (2015) LAMC2 enhances the metastatic potential of lung adenocarcinoma. Cell Death & Differentiation 22:8, pages 1341-1352.
Crossref
Crossref
Ravi Thakur, Rachana Trivedi, Namrata Rastogi, Manisha Singh & Durga Prasad Mishra. (2015) Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Scientific Reports 5:1.
Crossref
Crossref
Chong Won Choi, Yoon Hwan Kim, Jin Hee Sohn, Hyunjoo Lee & Won-Serk Kim. (2015) Focal adhesion kinase and Src expression in premalignant and malignant skin lesions. Experimental Dermatology 24:5, pages 361-364.
Crossref
Crossref
Yang Liu, Luwei Zhang, Yuanyuan Liu, Chao Sun, Hong Zhang, Guoying Miao, Cui Xia Di, Xin Zhou, Rong Zhou & Zhenhua Wang. (2015) DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. Journal of Cellular Physiology 230:5, pages 1094-1103.
Crossref
Crossref
Miriam Benezra, Evan Phillips, Michael Overholtzer, Pat B. Zanzonico, Esa Tuominen, Ulrich Wiesner & Michelle S. Bradbury. (2015) Ultrasmall Integrin-Targeted Silica Nanoparticles Modulate Signaling Events and Cellular Processes in a Concentration-Dependent Manner. Small 11:14, pages 1721-1732.
Crossref
Crossref
Divya Pathania, Yuting Kuang, Mario Sechi & Nouri Neamati. (2015) Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells. British Journal of Pharmacology 172:1, pages 50-63.
Crossref
Crossref
Elizabeth I. Tang, Dolores D. Mruk, Will M. Lee & C. Yan Cheng. 2015. Cell Polarity 1. Cell Polarity 1
303
326
.
Ching-Lung Liao, Ju-Hwa Lin, Jin-Cherng Lien, Shu-Chun Hsu, Fu-Shin Chueh, Chien-Chih Yu, Ping-Ping Wu, Yi-Ping Huang, Jaung-Geng Lin & Jing-Gung Chung. (2015)
The crude extract of
Corni Fructus
inhibits the migration and invasion of U-2 OS human osteosarcoma cells through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling
. Environmental Toxicology 30:1, pages 53-63.
Crossref
Crossref
Stefanie Aust, Katharina Auer, Anna Bachmayr-Heyda, Carsten Denkert, Jalid Sehouli, Ioana Braicu, Sven Mahner, Sandrina Lambrechts, Ignace Vergote, Christoph Grimm, Reinhard Horvat, Dan Cacsire Castillo-Tong, Robert Zeillinger & Dietmar Pils. (2014) Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium. Molecular Cancer 13:1.
Crossref
Crossref
Florian J. Sulzmaier, Christine Jean & David D. Schlaepfer. (2014) FAK in cancer: mechanistic findings and clinical applications. Nature Reviews Cancer 14:9, pages 598-610.
Crossref
Crossref
CHAO-LIN KUO, KUANG-CHI LAI, YI-SHIH MA, SHU-WEN WENG, JING-PIN LIN & JING-GUNG CHUNG. (2014) Gallic acid inhibits migration and invasion of SCC-4 human oral cancer cells through actions of NF-κB, Ras and matrix metalloproteinase-2 and -9. Oncology Reports 32:1, pages 355-361.
Crossref
Crossref
H.T. Wan, Dolores D. Mruk, Elizabeth I. Tang, Xiang Xiao, Yan-Ho Cheng, Elissa W.P. Wong, Chris K.C. Wong & C. Yan Cheng. (2014) Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis. Seminars in Cell & Developmental Biology 30, pages 65-74.
Crossref
Crossref
Victoria L. Herrera, Julius L. Decano, Glaiza A. Tan, Ann M. Moran, Khristine A. Pasion, Yuichi Matsubara & Nelson Ruiz-Opazo. (2014) DEspR Roles in Tumor Vasculo-Angiogenesis, Invasiveness, CSC-Survival and Anoikis Resistance: A ‘Common Receptor Coordinator’ Paradigm. PLoS ONE 9:1, pages e85821.
Crossref
Crossref
Katsuhiro Kinoshita, Yoshinori Aono, Momoyo Azuma, Jun Kishi, Akio Takezaki, Masami Kishi, Hideki Makino, Hiroyasu Okazaki, Hisanori Uehara, Keisuke Izumi, Saburo Sone & Yasuhiko Nishioka. (2013) Antifibrotic Effects of Focal Adhesion Kinase Inhibitor in Bleomycin-Induced Pulmonary Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology 49:4, pages 536-543.
Crossref
Crossref
Shu-Chun Hsu, Ju-Hwa Lin, Shu-Wen Weng, Fu-Shin Chueh, Chien-Chih Yu, Kung-Wen Lu, W. Gibson Wood & Jing-Gung Chung. (2013) Crude extract of Rheum palmatum inhibits migration and invasion of U-2 OS human osteosarcoma cells by suppression of matrix metalloproteinase-2 and -9. BioMedicine 3:3, pages 120-129.
Crossref
Crossref
Ioannis Roxanis. (2013) Occurrence and significance of epithelial-mesenchymal transition in breast cancer. Journal of Clinical Pathology 66:6, pages 517-521.
Crossref
Crossref
Xiaojing Qian, Dolores D. Mruk, Elissa W. P. Wong, Pearl P. Y. Lie & C. Yan Cheng. (2013) Palladin Is a Regulator of Actin Filament Bundles at the Ectoplasmic Specialization in Adult Rat Testes. Endocrinology 154:5, pages 1907-1920.
Crossref
Crossref
Oisun Jung, Yoon-Ju Choi, Tae Kyoung Kwak, Minkyung Kang, Mi-Sook Lee, Jihye Ryu, Hye-Jin Kim & Jung Weon Lee. (2013) The COOH-terminus of TM4SF5 in hepatoma cell lines regulates c-Src to form invasive protrusions via EGFR Tyr845 phosphorylation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1833:3, pages 629-642.
Crossref
Crossref
David Lagares & Mohit Kapoor. (2012) Targeting Focal Adhesion Kinase in Fibrotic Diseases. BioDrugs 27:1, pages 15-23.
Crossref
Crossref
Gerald W. Prager & Christoph C. Zielinski. 2013. Biochemical Basis and Therapeutic Implications of Angiogenesis. Biochemical Basis and Therapeutic Implications of Angiogenesis
335
356
.
Oisun Jung, Suyong Choi, Sun-Bok JangSin-Ae Lee, Ssang-Taek Lim, Yoon-Ju Choi, Hye-Jin Kim, Do-Hee KimTae Kyoung Kwak, Hyeonjung Kim, Minkyung KangMi-Sook Lee, Sook Young ParkJihye Ryu, Doyoung Jeong, Hae-Kap CheongHyun Jeong KimKi Hun ParkBong-Jin LeeDavid D. Schlaepfer & Jung Weon Lee. (2012) Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells. Journal of Cell Science 125:24, pages 5960-5973.
Crossref
Crossref
Hosam A Elbaz, Todd A Stueckle, William Tse, Yon Rojanasakul & Cerasela Zoica Dinu. (2012) Digitoxin and its analogs as novel cancer therapeutics. Experimental Hematology & Oncology 1:1.
Crossref
Crossref
Justin N. Bottsford-MillerRobert L. ColemanAnil K. Sood. (2012) Resistance and Escape From Antiangiogenesis Therapy: Clinical Implications and Future Strategies. Journal of Clinical Oncology 30:32, pages 4026-4034.
Crossref
Crossref
C.-L. Tang, H.-B. Zhao, M.-Q. Li, M.-R. Du, Y.-H. Meng & D.-J. Li. (2012) Focal Adhesion Kinase Signaling is Necessary for the Cyclosporin A-Enhanced Migration and Invasion of Human Trophoblast Cells. Placenta 33:9, pages 704-711.
Crossref
Crossref
Dorothee Fried, Beate B. Böhm, Kristin Krause & Harald Burkhardt. (2012) ADAM15 Protein Amplifies Focal Adhesion Kinase Phosphorylation under Genotoxic Stress Conditions. Journal of Biological Chemistry 287:25, pages 21214-21223.
Crossref
Crossref
Lu Zhou & C. Oliver Hanemann. (2012) Merlin, a multi-suppressor from cell membrane to the nucleus. FEBS Letters 586:10, pages 1403-1408.
Crossref
Crossref
Janaina Fernandes, Patrícia G. Guedes, Celso Luiz S. Lage, Juliany Cola F. Rodrigues & Claudia de Alencar S. Lage. (2012) Tumor malignancy is engaged to prokaryotic homolog toolbox. Medical Hypotheses 78:4, pages 435-441.
Crossref
Crossref
Muralidharan Anbalagan, Krzysztof Moroz, Alaa Ali, Latonya Carrier, Seth Glodowski & Brian G. Rowan. (2012) Subcellular Localization of Total and Activated Src Kinase in African American and Caucasian Breast Cancer. PLoS ONE 7:3, pages e33017.
Crossref
Crossref
C. Yan Cheng & Dolores D. Mruk. (2012) The Blood-Testis Barrier and Its Implications for Male Contraception. Pharmacological Reviews 64:1, pages 16-64.
Crossref
Crossref
Cláudia Alessandra Andrade de Paula, Vivien Jane Coulson-Thomas, Joana Gasperazzo Ferreira, Paloma Korehisa Maza, Erika Suzuki, Adriana Miti Nakahata, Helena Bonciani Nader, Misako Uemura Sampaio & Maria Luiza V. Oliva. (2012) Enterolobium contortisiliquum Trypsin Inhibitor (EcTI), a Plant Proteinase Inhibitor, Decreases in Vitro Cell Adhesion and Invasion by Inhibition of Src Protein-Focal Adhesion Kinase (FAK) Signaling Pathways. Journal of Biological Chemistry 287:1, pages 170-182.
Crossref
Crossref
Giovanni A. Infusino & Jeffrey R. Jacobson. (2012) Endothelial FAK as a therapeutic target in disease. Microvascular Research 83:1, pages 89-96.
Crossref
Crossref
Hyeonjung Kim, Oisun Jung, Minkyung Kang, Mi-Sook Lee, Doyoung Jeong, Jihye Ryu, Youra Ko, Yoon-Ju Choi & Jung Weon Lee. (2012) JNK signaling activity regulates cell–cell adhesions via TM4SF5-mediated p27Kip1 phosphorylation. Cancer Letters 314:2, pages 198-205.
Crossref
Crossref
Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu & Xiufeng Pang. (2011) Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway. Journal of Pharmacology and Experimental Therapeutics 339:2, pages 403-411.
Crossref
Crossref
S. Mruthyunjaya, Manchanda Rumma, Godbole Ravibhushan, Shiras Anjali & Shastry Padma. (2011) c-Jun/AP-1 transcription factor regulates laminin-1-induced neurite outgrowth in human bone marrow mesenchymal stem cells: Role of multiple signaling pathways. FEBS Letters 585:12, pages 1915-1922.
Crossref
Crossref
X. Pang, L. Zhang, L. Lai, J. Chen, Y. Wu, Z. Yi, J. Zhang, W. Qu, B. B. Aggarwal & M. Liu. (2011) 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis 32:6, pages 904-912.
Crossref
Crossref
Elissa W.P. Wong & C. Yan Cheng. (2011) Impacts of environmental toxicants on male reproductive dysfunction. Trends in Pharmacological Sciences 32:5, pages 290-299.
Crossref
Crossref
Yangsoon LeeSu Jin KimHye Jin MinJi Yoon JoEun Hye ParkSang Seok Koh. (2011) PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase. Experimental and Molecular Medicine 43:5, pages 291.
Crossref
Crossref
Andreas Desiniotis & Natasha Kyprianou. 2011.
117
147
.