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Review

Weight neutrality with the DPP-4 inhibitor, vildagliptin: Mechanistic basis and clinical experience

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Pages 541-548 | Published online: 01 Jul 2010

Keep up to date with the latest research on this topic with citation updates for this article.

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Piyush Verma, Lajpreet Kaur, Priyanka Aswal, Anju Singh, Himanshu Ojha, Afreen Jahan Rahman, Rahul Singhal, Anjani K. Tiwari & Mallika Pathak. (2023) Luminescence studies of binding affinity of vildagliptin with bovine serum albumin. Journal of Biomolecular Structure and Dynamics 41:7, pages 3002-3013.
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Ashwani Sharma, Tarun Virmani, Anjali Sharma, Vaishnavi Chhabra, Girish Kumar, Kamla Pathak & Abdulsalam Alhalmi. (2022) Potential Effect of DPP-4 Inhibitors Towards Hepatic Diseases and Associated Glucose Intolerance. Diabetes, Metabolic Syndrome and Obesity 15, pages 1845-1864.
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Viswanathan Mohan, Abdul Zargar, Manoj Chawla, Ameya Joshi, Usha Ayyagari, Bipin Sethi, Kumar Gaurav, Usha Rani H Patted, Seema Vikas Bhagat & Amey Ishwara Mane. (2021) Efficacy of a Combination of Metformin and Vildagliptin in Comparison to Metformin Alone in Type 2 Diabetes Mellitus: A Multicentre, Retrospective, Real-World Evidence Study. Diabetes, Metabolic Syndrome and Obesity 14, pages 2925-2933.
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Gail Fernandes, Joana E. Matos, Dena H. Jaffe, Grace Beyer, Lingfeng Yang, Kristy Iglay, Ira Gantz & Swapnil Rajpathak. (2020) Factors associated with the discontinuation of dipeptidyl peptidase-4 inhibitors (DPP-4is) after initiation of insulin. Current Medical Research and Opinion 36:3, pages 377-386.
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Charles Saab, Feryal A Al-Saber, Jihad Haddad, Mahir Khalil Jallo, Habib Steitieh, Giovanni Bader & Mohamed Ibrahim. (2015) Effectiveness and tolerability of second-line treatment with vildagliptin versus other oral drugs for type 2 diabetes in a real-world setting in the Middle East: results from the EDGE study. Vascular Health and Risk Management 11, pages 149-155.
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Matthias Blüher, Anja Schweizer, Giovanni Bader & James E Foley. (2014) Changes in body weight after 24 weeks of vildagliptin therapy as a function of fasting glucose levels in patients with type 2 diabetes. Vascular Health and Risk Management 10, pages 661-664.
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R. Göke, J. B. Gruenberger, G. Bader & M. Dworak. (2014) Real-life efficacy and safety of vildagliptin compared with sulfonylureas as add-on to metformin in patients with type 2 diabetes mellitus in Germany. Current Medical Research and Opinion 30:5, pages 785-789.
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Ibrahim Gueler, Susanne Mueller, Matthias Helmschrott, Christian U Oeing, Christian Erbel, Lutz Frankenstein, Christian Gleißner, Arjang Ruhparwar, Philipp Ehlermann, Thomas J Dengler, Hugo A Katus & Andreas O Doesch. (2013) Effects of vildagliptin (Galvus®) therapy in patients with type 2 diabetes mellitus after heart transplantation. Drug Design, Development and Therapy 7, pages 297-303.
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Bernard Charbonnel, Anja Schweizer & Sylvie Dejager. (2013) Combination Therapy With DPP-4 Inhibitors and Insulin in Patients With Type 2 Diabetes Mellitus: What Is the Evidence?. Hospital Practice 41:2, pages 93-107.
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Sylvie Dejager, Anja Schweizer & James E Foley. (2012) Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus. Vascular Health and Risk Management 8, pages 339-348.
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Sylvie Dejager & Anja Schweizer. (2012) Incretin Therapies in the Management of Patients with Type 2 Diabetes Mellitus and Renal Impairment. Hospital Practice 40:2, pages 7-21.
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André J Scheen. (2012) A review of gliptins in 2011. Expert Opinion on Pharmacotherapy 13:1, pages 81-99.
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Mohamed Hassanein, Wasim Hanif, Waqar Malik, Ali Kamal, Parnia Geransar, Nicola Lister, Chris Andrews & Anthony Barnett. (2011) Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study. Current Medical Research and Opinion 27:7, pages 1367-1374.
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