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Original Article

The Control of Dicumarol Therapy and the Quantitative Determination of Prothrombin and Proconvertin

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Pages 201-208 | Received 30 Jul 1951, Published online: 13 May 2010

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Read on this site (68)

Tomas L. Lindahl, Kerstin Arbring, Maria Wallstedt & Mats Rånby. (2017) A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs). Upsala Journal of Medical Sciences 122:3, pages 171-176.
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Abdmajid Osman & Tomas L. Lindahl. (2009) Plasma predilution with addition of depleted plasma in a prothrombin time reagent improves the agreement between different prothrombin time methods. Scandinavian Journal of Clinical and Laboratory Investigation 69:3, pages 395-400.
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J. W. J. Van Wersch. (1993) Evaluation of a new chromogenic substrate assay for the measurement of the prothrombin time. Scandinavian Journal of Clinical and Laboratory Investigation 53:6, pages 563-568.
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J. Agnholt, J. H. Mikkelsen, M. ÍBud, J. Møller-Petersen, S. N. Rasmussen & J. Dyerberg. (1990) Plasma Prekallikrein as a Prognostic Indicator in Chronic Liver Insufficiency. Scandinavian Journal of Gastroenterology 25:1, pages 40-44.
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LouiseM. Canfield, JamesJ. Corrigan$suffix/text()$suffix/text(), PatriciaM. Plezia, Monette Jeter, Susan Sayers & DavidS. Alberts. (1990) Effects of chronic β‐carotene supplementation on vitamin K status in adults. Nutrition and Cancer 13:4, pages 263-269.
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J. Boos, H. Pollmann & H. C. Dominick. (1989) Vitamin K-Dependent Coagulation Parameters During the First Six Days of Life: Incidence of PIVKA II in Newborns. Pediatric Hematology and Oncology 6:2, pages 113-119.
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Christine Felding & Elisabeth Jul. (1988) Maternal Prophylactic Vitamin K Treatment and Response in Cord Plasma of Coagulation Factor (II, VII, X) Activity. Pediatric Hematology and Oncology 5:1, pages 77-80.
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. (1987) 7. Bibliography. Scandinavian Journal of Clinical and Laboratory Investigation 47:sup187, pages 76-91.
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H. U. Nuutinen. (1986) Activities of Ethanol-Metabolizing Enzymes in Liver Diseases. Scandinavian Journal of Gastroenterology 21:6, pages 678-684.
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H Ekelund & U Hedner. (1984) Prothrombin and vitamin K deficiency in the newborn. European Paediatric Haematology and Oncology 1:1, pages 59-65.
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Johannes Mejer & Vagn Reinicke. (1983) Changes in some nucleoside metabolizing enzymes of lymphocytes and granulocytes from patients with cirrhosis of the liver. Scandinavian Journal of Clinical and Laboratory Investigation 43:3, pages 227-232.
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B. L. Persson, L. Holmberg, B. Åstedt & I. M. Nilsson. (1982) Coagulation and Fibrinolysis in Pregnancy Complicated by Intrauterine Growth Retardation. Acta Obstetricia et Gynecologica Scandinavica 61:5, pages 455-459.
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P. Felding, P. Hyltoft Petersen & M. Hørder. (1981) The stability of blood, plasma and serum constituents during simulated transport. Scandinavian Journal of Clinical and Laboratory Investigation 41:1, pages 35-40.
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Lilian Tengborn, Birgitta Frohm, L. E. Nilsson & Inga Marie Nilsson. (1981) Antithrombin III concentrate: its catabolism in health and in antithrombin III deficiency. Scandinavian Journal of Clinical and Laboratory Investigation 41:5, pages 469-477.
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Lars Svanberg, Kurt Bernstein, Stig Kullander & Birger Åstedt. (1980) Effect of Dihydroergotamine on Coagulation Factors and Components of the Fibrinolytic System. Acta Obstetricia et Gynecologica Scandinavica 59:3, pages 251-253.
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Lars Svanberg, Birger Åstedt & Inga Marie Nilsson. (1980) Abruptio Placentae—Treatment with the Fibrinolytic Inhibitor Tranexamic Acid. Acta Obstetricia et Gynecologica Scandinavica 59:2, pages 127-130.
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Jørgen Falck Larsen, Bo Jacobsen, Hans Henrik Holm, Jan Fog Pedersen & Margit Mantoni. (1978) Intrauterine injection of vitamin k before the delivery during anticoagulant therapy of the mother. Acta Obstetricia et Gynecologica Scandinavica 57:3, pages 227-230.
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Stig Kullander, Lars Svanberg & Birger åstedt. (1977) Coagulative and Fibrinolytic Studies on Postmenopausal Women Treated with a New Non-Steroidal Oestrogen. Acta Obstetricia et Gynecologica Scandinavica 56:4, pages 371-374.
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Ib Andersen & Sixtus Thorsen. (1977) The application of the Reaction Rate Analyser LKB 8600 as an automatic coagulometer. Scandinavian Journal of Clinical and Laboratory Investigation 37:1, pages 7-13.
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A. Uldall, R. Dybkær, M. Lauritzen & K. Rolighed. (1972) Mathematical Expressions of Measuring Curves for Concentration of Clotting Factors. Scandinavian Journal of Clinical and Laboratory Investigation 29:4, pages 417-419.
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A. Uldall & R. Dybkær. (1972) Reduction of Analytical Error in Measurement of the Concentration of Coagulation Factors in Plasma. Scandinavian Journal of Clinical and Laboratory Investigation 29:4, pages 413-416.
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K. Varis, R. Koskinen, J. Jussila, T. Rytömaa, S. Tarpila & K. Launiala. (1971) The Effect of Some Antituberculous Drugs upon the Upper Gastrointestinal Tract: an Experiment with Para-Aminosalicylic Acid, Isoniazid, and Streptomycin. Scandinavian Journal of Gastroenterology 6:7, pages 589-595.
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L. Ranek, V. Andersen, S. Jarnum, J. Nerup, K. Ramsöe, T. Schiödt, N. Tygstrup, B. Weeke & H. Westergaard. (1971) Extracorporeal Irradiation of the Blood: Attempted Immunosuppressive Treatment of Active, Non-Alcoholic Cirrhosis. Scandinavian Journal of Gastroenterology 6:5, pages 389-396.
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P. O. Ganrot & J. E. Nilehn. (1971) Synthesis of an Abnormal Prothrombin in Malnutrition and Biliary Obstruction and during Dicumarol Treatment. Scandinavian Journal of Clinical and Laboratory Investigation 28:3, pages 245-249.
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P. O. Ganrot & J. Stenflo. (1970) Prothrombin Derivatives in Human Serum. Isolation and Some Properties of the Non-Thrombin Fragments. Scandinavian Journal of Clinical and Laboratory Investigation 26:2, pages 161-168.
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K. Ramsöe, N. Tygstrup & P. Winkel. (1970) The Redundancy of Liver Tests in the Diagnosis of Cirrhosis Estimated by Multivariate Statistics. Scandinavian Journal of Clinical and Laboratory Investigation 26:4, pages 307-312.
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Ingrid Norén. (1970) Specific Assay of Prothrombin. Scandinavian Journal of Clinical and Laboratory Investigation 25:1, pages 47-58.
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Ulf Ljungqvist, Sven-Erik Bergentz, Lennart Leandoer & Inga Marie Nilsson. (1969) Coagulation and Fibrinolysis After Renal Transplantation. Scandinavian Journal of Urology and Nephrology 3:1, pages 23-29.
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Niels Chr. Nielsen. (1969) Coagulation and Fibrinolysis in Normal Women Immediately Post Partum and in Newborn Infants: Influence of Prophylactic Vitamin K. Acta Obstetricia et Gynecologica Scandinavica 48:3, pages 371-391.
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P. O. Ganrot & J.-E. Niléhn. (1968) Plasma Prothrombin during Treatment with Dicumarol. Scandinavian Journal of Clinical and Laboratory Investigation 22:1, pages 28-28.
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J. E. Niléhn & P. O. Ganrot. (1968) Plasma Prothrombin during Treatment with Dicumarol. Scandinavian Journal of Clinical and Laboratory Investigation 22:1, pages 17-22.
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P. O. Ganrot & J. E. Niléhn. (1968) Immunochemical Determination of Human Prothrombin. Scandinavian Journal of Clinical and Laboratory Investigation 21:3, pages 238-244.
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O. Almersjö, S. Bergmark, L. Engevik, K. Korsan-Bengtsen & J. Ygge. (1967) The Coagulation Defect after Extensive Liver Resection in Man. Scandinavian Journal of Gastroenterology 2:3, pages 204-208.
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C. J. Amris & J. Starup. (1967) The Coagulation Mechanism in Oral Contraception. Acta Obstetricia et Gynecologica Scandinavica 46:1, pages 78-91.
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C. J. Amris & J. Kjeldsen. (1966) Hæmorrhagic Diathesis Due to Abruptio Placentæ Treated with Trasylol. Acta Obstetricia et Gynecologica Scandinavica 45:2, pages 180-195.
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S. M. Samuelsson & Gunvor Lilienberg. (1965) Do Barbiturates Influence the Prothrombin-Proconvertin Level During Anticoagulant Therapy?. Scandinavian Journal of Clinical and Laboratory Investigation 17:1, pages 73-79.
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K. Pyörälä & M. Kekki. (1963) Decreased Anticoagulant Tolerance During Methandrostenolone Therapy. Scandinavian Journal of Clinical and Laboratory Investigation 15:4, pages 367-374.
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A. Nordøy. (1963) Difference in the Heparin-Neutralizing Effect of Protamine and Polybrene as Tested by Thrombotest. Scandinavian Journal of Clinical and Laboratory Investigation 15:3, pages 205-210.
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O. Egeberg. (1963) The effect of edema drainage on the blood clotting system. Scandinavian Journal of Clinical and Laboratory Investigation 15:1, pages 14-19.
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Ole K. Albrechtsen & Preben Skjødt. (1963) The Effect of Epsilon-Aminocaproic Acid on Uterine Hæmorrhage. Acta Obstetricia et Gynecologica Scandinavica 42:2, pages 160-180.
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C. J. Amris, V. Larsen, B. Mogensen & O. Storm. (1963) Infusion of porcine plasmin in man. Studies on toxicology and pharmacodynamics. Scandinavian Journal of Clinical and Laboratory Investigation 15:2, pages 179-188.
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Erik Nettelbladt. (1962) On Some Liver Functions in Rheumatoid Arthritis. Acta Rheumatologica Scandinavica 8:1-4, pages 63-80.
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O. Egeberg. (1962) Blood Coagulation in Renal Failure. Scandinavian Journal of Clinical and Laboratory Investigation 14:2, pages 163-169.
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E. Magid. (1962) Tolerance to Anticoagulants During Antibiotic Therapy. Scandinavian Journal of Clinical and Laboratory Investigation 14:5, pages 565-566.
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O. Egeberg. (1962) A Family with Antihemophilic C Factor (AHC = Plasma Thromboplastin Antecedent) Deficiency Without Bleeding Tendency. Scandinavian Journal of Clinical and Laboratory Investigation 14:5, pages 478-486.
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P. Ollendorff. (1962) The Nature of the Anticoagulant Effect of Heparin, Protamine, Polybrene and Toluidine Blue. Scandinavian Journal of Clinical and Laboratory Investigation 14:3, pages 267-276.
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P. Ollendorff. (1962) Initiation of blood clotting and glass activation followed with a three-stage technique. Scandinavian Journal of Clinical and Laboratory Investigation 14:6, pages 641-647.
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O. Egeberg. (1961) Acquired Circulating Anticoagulant in Classical Hemophilia. Scandinavian Journal of Clinical and Laboratory Investigation 13:4, pages 535-544.
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O. Egeberg. (1961) Assay of Antihemophilic a, b and c Factors by One-Stage Cephalin Systems. Scandinavian Journal of Clinical and Laboratory Investigation 13:1, pages 140-152.
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R. Gordin. (1960) Certain Aspects of the Thrombotest Method for the Control of Anticoagulant Therapy. Scandinavian Journal of Clinical and Laboratory Investigation 12:3, pages 329-332.
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Arthur H. Sanford & Sherwood P. Miller. (1959) Laboratory notes. Postgraduate Medicine 25:3, pages A-38-A-46.
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H. Dyggve. (1958) Comparison Between Micro-Modifications of Prothrombin-Proconvertin Determinations and of the Prothrombin Time Method. Scandinavian Journal of Clinical and Laboratory Investigation 10:1, pages 1-4.
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Jørgen Løvset, Knut Knutsen & Aage Jakobsen. (1957) Treatment with Anticoagulants of Pregnant Women with Previous Severe Tox/Emia. Acta Obstetricia et Gynecologica Scandinavica 36:4, pages 492-498.
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B. A. Waaler. (1957) Simultaneous Contribution to the Formation of Thrombin by the Intrinsic and Extrinsic Blood Clotting Systems. Scandinavian Journal of Clinical and Laboratory Investigation 9:4, pages 322-330.
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P. A. Owren. (1957) The Technic of Permanent Anticoagulant Treatment. Postgraduate Medicine 21:1, pages 83-90.
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S. E. Bjørkman, C. B. Laurell & I.-M. Nilsson. (1956) Serum Proteins and Fibrinolysis in Polycythemia Vera. Scandinavian Journal of Clinical and Laboratory Investigation 8:4, pages 304-308.
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E. Rosling & E. Schoenheyder. (1955) Micromethod for Owren's Prothrombin Determination. Scandinavian Journal of Clinical and Laboratory Investigation 7:2, pages 171-174.
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Erling Lund, Torben Geill, Ebbe Söndergaard & Henrik Dam. (1955) Comparison of the prothrombin—proconvertin determinations owren—aas with “prothrombin—index” obtained with the larsen—plum prothrombin time method. Scandinavian Journal of Clinical and Laboratory Investigation 7:1, pages 69-74.
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R. Gordin & B Kuhlbäck. (1954) A Bed-Side “Prothrombin” Method for Use in Anticoagulant Therapy. Scandinavian Journal of Clinical and Laboratory Investigation 6:2, pages 155-159.
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T. Geill, E. Lund, H. Dam & E Søndergaard. (1954) Studies on the Efficiency of Vitamin K1 in Small Doses as Antidote Against Anticoagulants of the Dicoumarol Type. Scandinavian Journal of Clinical and Laboratory Investigation 6:3, pages 203-209.
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Samuel I. Rapaport, Knut Aas & Paul A. Owren. (1954) The Coagulant Activity of Russel Viper Venom. Scandinavian Journal of Clinical and Laboratory Investigation 6:1, pages 81-81.
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H. Brodthagen. (1953) The Preparation of Prothrombin-Free Ox Plasma in the Estimation of Prothrombin. Scandinavian Journal of Clinical and Laboratory Investigation 5:4, pages 376-377.
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J. Dedichen. (1953) Long Term Anticoagulant Treatment of Cardiovascular Disorders with Phenylindandione (Pid-Trombantin). Scandinavian Journal of Clinical and Laboratory Investigation 5:4, pages 324-327.
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S. Mullertz. (1953) Dilution Curves and Accuracy in Prothrombin Estimations During Hepatitis and Dicumarol Therapy. Scandinavian Journal of Clinical and Laboratory Investigation 5:2, pages 179-187.
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M. Sundberg. (1953) Sensitized Clotting Time as a Clinical Method. Scandinavian Journal of Clinical and Laboratory Investigation 5:2, pages 172-174.
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