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Original Article

The blood serum concentration of cystatin C (γ-trace) as a measure of the glomerular filtration rate

, &
Pages 97-101 | Received 21 Jun 1984, Accepted 03 Sep 1984, Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (26)

Carl Ottosson Frost, Per Gille-Johnson, Emanuel Blomstrand, Viggo St-Aubin, Felicia Leion & Anders Grubb. (2022) Cystatin C-based equations for estimating glomerular filtration rate do not require race or sex coefficients. Scandinavian Journal of Clinical and Laboratory Investigation 82:2, pages 162-166.
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Satoshi Tanaka, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Masaaki Machino, Kyotaro Ota, Taisuke Seki, Koji Suzuki, Yoshihiro Nishida, Naoki Ishiguro, Yukiharu Hasegawa & Shiro Imagama. (2018) Serum cystatin C level is associated with locomotive syndrome risk and can be an early predictor in community-living people: The Yakumo study. Modern Rheumatology 28:6, pages 1035-1040.
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Anders Grubb, Veronica Lindström, Magnus Jonsson, Sten-Erik Bäck, Tomas Åhlund, Bengt Rippe & Anders Christensson. (2015) Reduction in glomerular pore size is not restricted to pregnant women. Evidence for a new syndrome: ‘Shrunken pore syndrome’. Scandinavian Journal of Clinical and Laboratory Investigation 75:4, pages 333-340.
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Xiao-Hua Pei, Juan He, Qiao Liu, Bei Zhu, Li-Hua Bao, Chen-Jing Yan, Jian-Qing Wu & Wei-Hong Zhao. (2012) Evaluation of serum creatinine- and cystatin C-based equations for the estimation of glomerular filtration rate in a Chinese population. Scandinavian Journal of Urology and Nephrology 46:3, pages 223-231.
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A. R. Saxena, S. Ananth Karumanchi, S.-L. Fan, G. L. Horowitz, N. K. Hollenberg, S. W. Graves & E. W. Seely. (2012) Correlation of Cystatin-C with Glomerular Filtration Rate by Inulin Clearance in Pregnancy. Hypertension in Pregnancy 31:1, pages 22-30.
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Lars-Olof Hansson, Anders Grubb, Anders Lidén, Mats Flodin, Annacarin Berggren, Joris Delanghe, Veronique Stove, Hilmar Luthe, Karl-Heinz Rhode, Claus Beck & Ingrid Domke. (2010) Performance evaluation of a turbidimetric cystatin C assay on different high-throughput platforms. Scandinavian Journal of Clinical and Laboratory Investigation 70:5, pages 347-353.
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Ying Ma, Qi Li, Jiuping Wang, Zhuwei Xu, Chaojun Song, Ran Zhuang, Kun Yang, Angang Yang & Boquan Jin. (2010) Cystatin C, a novel urinary biomarker for sensitive detection of acute kidney injury during haemorrhagic fever with renal syndrome. Biomarkers 15:5, pages 410-417.
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Sherif Saleh, Antonios V. Antoniou, Kevin Harrington & Joseph Aquilina. (2010) Second Trimester Maternal Serum Cystatin C Levels in Preeclamptic and Normotensive Pregnancies: A Small Case-Control Study. Hypertension in Pregnancy 29:1, pages 112-119.
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Gunnar Sterner, Jonas Björk, Joyce Carlson, Anders Grubb & Ulf Nyman. (2009) Validation of a new plasma cystatin C-based formula and the Modification of Diet in Renal Disease creatinine-based formula for determination of glomerular filtration rate. Scandinavian Journal of Urology and Nephrology 43:3, pages 242-249.
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Sanae Watanabe, Takafumi Okura, Mie Kurata, Jun Irita, Seiko Manabe, Ken-Ichi Miyoshi, Tomikazu Fukuoka, Akiko Gotoh, Kazuo Uchida & Jitsuo Higaki. (2006) Valsartan Reduces Serum Cystatin C and the Renal Vascular Resistance in Patients with Essential Hypertension. Clinical and Experimental Hypertension 28:5, pages 451-461.
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A. Grubb, J. Björk, V. Lindström, G. Sterner, P. Bondesson & U. Nyman. (2005) A cystatin C‐based formula without anthropometric variables estimates glomerular filtration rate better than creatinine clearance using the Cockcroft‐Gault formula. Scandinavian Journal of Clinical and Laboratory Investigation 65:2, pages 153-162.
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P. Sjöström, M. Tidman & I. Jones. (2005) Determination of the production rate and non‐renal clearance of cystatin C and estimation of the glomerular filtration rate from the serum concentration of cystatin C in humans. Scandinavian Journal of Clinical and Laboratory Investigation 65:2, pages 111-124.
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J. Moodley, R. Gangaram, R. Khanyile & P.J. Ojwang. (2004) Serum Cystatin C for Assessment of Glomerular Filtration Rate in Hypertensive Disorders of Pregnancy. Hypertension in Pregnancy 23:3, pages 309-317.
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Michele Mussap & Mario Plebani. (2004) Biochemistry and Clinical Role of Human Cystatin C. Critical Reviews in Clinical Laboratory Sciences 41:5-6, pages 467-550.
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Dijana Jovanović, Pavle Krstivojević, Ivana Obradović, Vesna Đurđević & Ljubica Đukanović. (2003) Serum Cystatin C and β2-Microglobulin as Markers of Glomerular Filtration Rate. Renal Failure 25:1, pages 123-133.
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Claudio Bianchi, Carlo Donadio, Gianfranco Tramonti, Cristina Consani, Paolo Lorusso, Chiara Bonino & Fabio Lunghi. (2001) UNINEPHRECTOMY INCREASES KIDNEY β2-MICROGLOBULIN: CAN IT PLAY A ROLE IN THE PROGRESSION OF KIDNEY DAMAGE?. Renal Failure 23:3-4, pages 507-516.
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Claudio Bianchi, Carlo Donadio, Gianfranco Tramonti, Cristina Consani, Paolo Lorusso & Giuseppe Rossi. (2001) REAPPRAISAL OF SERUM β2-MICROGLOBULIN AS MARKER OF GFR. Renal Failure 23:3-4, pages 419-429.
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E. Randers, K. Kornerup, E. J. Erlandsen, C. Hasling, H. Danielsen. (2001) Cystatin C levels in sera of patients with acute infectious diseases with high C-reactive protein levels. Scandinavian Journal of Clinical and Laboratory Investigation 61:4, pages 333-335.
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William F. Finn & George A. Porter. (1999) Urinary Biomarkers: Recommendations of the Joint European/United States Workshop for Future Research. Renal Failure 21:3-4, pages 445-451.
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L. Norlund, G. Fex, J. Lanke, H. von Schenck, J. E. Nilsson, H. Leksell & A. Grubb. (1997) Reference intervals for the glomerular filtration rate and cell-proliferation markers: serum cystatin C and serum β2-microglobulin/cystatin C-ratio. Scandinavian Journal of Clinical and Laboratory Investigation 57:6, pages 463-470.
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O. Tenstad, A. B. Roald, A. Grubb & K. Aukland. (1996) Renal handling of radiolabelled human cystatin C in the rat. Scandinavian Journal of Clinical and Laboratory Investigation 56:5, pages 409-414.
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Stefan C Lindgren, Carl-Bertil Laurell & Gunnar N Sterner. (1992) Plasma Protein Homeostasis in Chronic Hemodialysis Patients. Scandinavian Journal of Urology and Nephrology 26:3, pages 279-282.
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Allain Collé, Catherine Tavera, Patricia Laurent, Jeanne Leung-tack & Jean Pierre Girolami. (1990) Direct Radioimmunoassay of Rat Cystatin C: Increased Urinary Excretion of This Cysteine Proteases Inhibitor During Chromate Nephropathy. Journal of Immunoassay 11:2, pages 199-214.
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