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Original Article

A Double-Blind Placebo-Controlled Trial with Loperamide in Irritable Bowel Syndrome

, &
Pages 463-468 | Received 26 Apr 1995, Accepted 08 Nov 1995, Published online: 08 Jul 2009

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Read on this site (9)

Jennifer Jones, Anthony Lembo, Joel Heidelbaugh, Louis Kuritzky & Brian Lacy. (2021) Management of irritable bowel syndrome with diarrhea: focus on eluxadoline. Current Medical Research and Opinion 37:4, pages 567-578.
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Anna Zielińska, Maciej Sałaga, Marcin Włodarczyk & Jakub Fichna. (2018) Chronic abdominal pain in irritable bowel syndrome – current and future therapies. Expert Review of Clinical Pharmacology 11:7, pages 729-739.
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Brian E Lacy. (2016) Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome. International Journal of General Medicine 9, pages 7-17.
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Emidio Scarpellini, Lucrezia Laterza, Gianluca Ianiro, Jan Tack, Ludovico Abenavoli & Antonio Gasbarrini. (2016) Eluxadoline for the treatment of diarrhoea-predominant irritable bowel syndrome. Expert Opinion on Pharmacotherapy 17:10, pages 1395-1402.
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Simona Deiana, Tommaso Gabbani, Siro Bagnoli & Vito Annese. (2015) Emerging drug for diarrhea predominant irritable bowel syndrome. Expert Opinion on Emerging Drugs 20:2, pages 247-261.
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Michael Camilleri. (2013) Current and future pharmacological treatments for diarrhea-predominant irritable bowel syndrome. Expert Opinion on Pharmacotherapy 14:9, pages 1151-1160.
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Sylvie Bradesi, Kirsten Tillisch & Emeran Mayer. (2006) Emerging drugs for irritable bowel syndrome. Expert Opinion on Emerging Drugs 11:2, pages 293-313.
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Jong H Nam, Zaid Alnoah, Sudha R Yenumula & Sreekant Murthy. (2003) Epidemiology, pathogenesis and treatment of irritable bowel syndrome. Expert Opinion on Therapeutic Patents 13:8, pages 1213-1267.
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Ashkan Farhadi, Keith Bruninga, Jeremy Fields & Ali Keshavarzian. (2001) Irritable bowel syndrome: an update on therapeutic modalities. Expert Opinion on Investigational Drugs 10:7, pages 1211-1222.
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Crossref
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Crossref
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Crossref
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J Pannemans & M Corsetti. (2018) Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?. Current Opinion in Pharmacology 43, pages 53-58.
Crossref
John F. Jarrell, George A. Vilos, Catherine Allaire, Susan Burgess, Claude Fortin, Robert Gerwin, Louise Lapensée, Robert H. Lea, Nicholas A. Leyland, Paul Martyn, Hassan Shenassa & Paul Taenzer. (2018) No 164 - Directive clinique de consensus pour la prise en charge de la douleur pelvienne chronique. Journal of Obstetrics and Gynaecology Canada 40:11, pages e788-e836.
Crossref
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Victor Chedid, Priya Vijayvargiya & Michael Camilleri. (2018) Advantages and Limitations of the Federal Adverse Events Reporting System in Assessing Adverse Event Reporting for Eluxadoline. Clinical Gastroenterology and Hepatology 16:3, pages 336-338.
Crossref
A. Wasilewski, A. Misicka, M. Sacharczuk & J. Fichna. (2018) Prosecretory effect of loperamide in ileal and colonic mucosae of mice displaying high or low swim stress-induced analgesia associated with high and low endogenous opioid system activity. Neurogastroenterology & Motility 30:2, pages e13166.
Crossref
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Crossref
Yeong Yeh Lee, Chandramouli Annamalai & Satish S. C. Rao. (2017) Post-Infectious Irritable Bowel Syndrome. Current Gastroenterology Reports 19:11.
Crossref
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Crossref
Brian E Lacy, William D Chey, Brooks D Cash, Anthony J Lembo, Leonard S Dove & Paul S Covington. (2017) Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. American Journal of Gastroenterology 112:6, pages 924-932.
Crossref
V. Schindler & D. Pohl. (2017) Medikamentöse Therapien bei Reizmagen und ReizdarmDrug therapy for functional dyspepsia and irritable bowel syndrome. Der Gastroenterologe 12:2, pages 135-140.
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Longtu Chen, Sheikh J. Ilham & Bin Feng. (2017) Pharmacological Approach for Managing Pain in Irritable Bowel Syndrome: A Review Article. Anesthesiology and Pain Medicine 7:2.
Crossref
Chan Hyuk Park & Dong Soo Han. (2017) Pharmacotherapy of irritable bowel syndrome. Journal of the Korean Medical Association 60:1, pages 57.
Crossref
Isabel Vera & F. Javier Júdez. (2017) Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome. The SEPD perspective. Revista Española de Enfermedades Digestivas.
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Kamesh Gupta, Harparam Singh Ghuman & Shivani Vijay Handa. (2017) Review of Rifaximin: Latest Treatment Frontier for Irritable Bowel Syndrome Mechanism of Action and Clinical Profile. Clinical Medicine Insights: Gastroenterology 10, pages 117955221772890.
Crossref
Miguel Saps & Adrian Miranda. 2017. Gastrointestinal Pharmacology. Gastrointestinal Pharmacology 147 176 .
Rena K. Fox & Thiruvengadam Muniraj. (2016) Pharmacologic Therapies in Gastrointestinal Diseases. Medical Clinics of North America 100:4, pages 827-850.
Crossref
Brian E. Lacy, Fermín Mearin, Lin Chang, William D. Chey, Anthony J. Lembo, Magnus Simren & Robin Spiller. (2016) Bowel Disorders. Gastroenterology 150:6, pages 1393-1407.e5.
Crossref
Paul Enck, Qasim Aziz, Giovanni Barbara, Adam D. Farmer, Shin Fukudo, Emeran A. Mayer, Beate Niesler, Eamonn M. M. Quigley, Mirjana Rajilić-Stojanović, Michael Schemann, Juliane Schwille-Kiuntke, Magnus Simren, Stephan Zipfel & Robin C. Spiller. (2016) Irritable bowel syndrome. Nature Reviews Disease Primers 2:1.
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Anthony J. Lembo, Brian E. Lacy, Marc J. Zuckerman, Ron Schey, Leonard S. Dove, David A. Andrae, J. Michael Davenport, Gail McIntyre, Rocio Lopez, Lisa Turner & Paul S. Covington. (2016) Eluxadoline for Irritable Bowel Syndrome with Diarrhea. New England Journal of Medicine 374:3, pages 242-253.
Crossref
Robin Spiller. (2016) Irritable bowel syndrome: new insights into symptom mechanisms and advances in treatment. F1000Research 5, pages 780.
Crossref
B. E. Lacy. (2016) Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS. Neurogastroenterology & Motility 28:1, pages 26-35.
Crossref
Gregory S. Sayuk & C. Prakash Gyawali. (2015) Irritable Bowel Syndrome: Modern Concepts and Management Options. The American Journal of Medicine 128:8, pages 817-827.
Crossref
Fred M. Howard & Miya P. Yamamoto. 2015. Clinical Gynecology. Clinical Gynecology 51 74 .
. 2015. Clinical Gynecology. Clinical Gynecology 1 202 .
Azadeh Rezvan, Sharon Jakus-Waldman, Maher A. Abbas, Tajnoos Yazdany & John Nguyen. (2015) Review of the Diagnosis, Management and Treatment of Fecal Incontinence. Female Pelvic Medicine & Reconstructive Surgery 21:1, pages 8-17.
Crossref
Justin Sirianni, Mohab Ibrahim & Amol Patwardhan. 2015. Molecular and Cell Biology of Pain. Molecular and Cell Biology of Pain 565 611 .
Shin Fukudo, Hiroshi Kaneko, Hirotada Akiho, Masahiko Inamori, Yuka Endo, Toshikatsu Okumura, Motoyori Kanazawa, Takeshi Kamiya, Ken Sato, Toshimi Chiba, Kenji Furuta, Shigeru Yamato, Tetsuo Arakawa, Yoshihide Fujiyama, Takeshi Azuma, Kazuma Fujimoto, Tetsuya Mine, Soichiro Miura, Yoshikazu Kinoshita, Kentaro Sugano & Tooru Shimosegawa. (2014) Evidence-based clinical practice guidelines for irritable bowel syndrome. Journal of Gastroenterology 50:1, pages 11-30.
Crossref
Christopher T. McNabb, Michelle M. White, Amber L. Harris & Perry N. Fuchs. (2014) The elusive rat model of conditioned placebo analgesia. Pain 155:10, pages 2022-2032.
Crossref
Jose L. Barboza, Nicholas J. Talley & Baharak Moshiree. (2014) Current and Emerging Pharmacotherapeutic Options for Irritable Bowel Syndrome. Drugs 74:16, pages 1849-1870.
Crossref
H. L. DuPont. (2014) Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets. Alimentary Pharmacology & Therapeutics 39:10, pages 1033-1042.
Crossref
Rosa LS Soares. (2014) Irritable bowel syndrome: A clinical review. World Journal of Gastroenterology 20:34, pages 12144.
Crossref
Katy E. Trinkley & Milap C. Nahata. (2014) Medication Management of Irritable Bowel Syndrome. Digestion 89:4, pages 253-267.
Crossref
Brian E. Lacy & Tracia OʼShana. (2014) Clinical Pearls for Irritable Bowel Syndrome. Gastroenterology Nursing 37:6, pages 392-405.
Crossref
Magnus Simrén & Hans TörnblomEleni Athanasakos & Anton Emmanuel. 2013. Irritable Bowel Syndrome: Diagnosis and Management. Irritable Bowel Syndrome: Diagnosis and Management 171 193 .
Magnus Simrén & Hans TörnblomMichael Camilleri. 2013. Irritable Bowel Syndrome: Diagnosis and Management. Irritable Bowel Syndrome: Diagnosis and Management 105 129 .
Hans Törnblom & Magnus Simrén. 2013. Irritable Bowel Syndrome. Irritable Bowel Syndrome 277 299 .
Natasha A. Koloski & Nicholas J. Talley. 2013. Women and Health. Women and Health 1353 1365 .
Ulrike Voß, Anne Lewerenz & Karen Nieber. 2012. Sex and Gender Differences in Pharmacology. Sex and Gender Differences in Pharmacology 473 497 .
Stacy Menees, Richard Saad & William D. Chey. (2012) Agents that act luminally to treat diarrhoea and constipation. Nature Reviews Gastroenterology & Hepatology 9:11, pages 661-674.
Crossref
Thomas Shima. (2012) Diagnosis and management of irritable bowel syndrome. Osteopathic Family Physician 4:6, pages 172-175.
Crossref
Arnold Wald. (2012) Irritable bowel syndrome – Diarrhoea. Best Practice & Research Clinical Gastroenterology 26:5, pages 573-580.
Crossref
Robin Spiller & Ching Lam. (2012) An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome. Journal of Neurogastroenterology and Motility 18:3, pages 258-268.
Crossref
Viola Andresen, Jutta Keller, Christian Pehl, Michael Schemann, Jan Preiss & Peter Layer. (2011) Irritable Bowel Syndrome. Deutsches Ärzteblatt international.
Crossref
William D. Chey, Monthira Maneerattaporn & Richard Saad. (2011) Pharmacologic and Complementary and Alternative Medicine Therapies for Irritable Bowel Syndrome. Gut and Liver 5:3, pages 253-266.
Crossref
K. E. Trinkley & M. C. Nahata. (2011) Treatment of irritable bowel syndrome. Journal of Clinical Pharmacy and Therapeutics 36:3, pages 275-282.
Crossref
Richard J. Saad. (2011) Peripherally Acting Therapies for the Treatment of Irritable Bowel Syndrome. Gastroenterology Clinics of North America 40:1, pages 163-182.
Crossref
Joong Goo KwonKyung Sik ParkJung Ho ParkJae Myung ParkCheol Hee ParkKwang Jae LeeHyo-Jin ParkJong Chul Rhee. (2011) Guidelines for the Treatment of Irritable Bowel Syndrome. The Korean Journal of Gastroenterology 57:2, pages 82.
Crossref
Sarah Khan & Lin Chang. (2010) Diagnosis and management of IBS. Nature Reviews Gastroenterology & Hepatology 7:10, pages 565-581.
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Kok-Ann Gwee, Young-Tae Bak, Uday Chand Ghoshal, Sutep Gonlachanvit, Oh Young Lee, Kwong Ming Fock, Andrew Seng Boon Chua, Ching-Liang Lu, Khean-Lee Goh, Chomsri Kositchaiwat, Govind Makharia, Hyo-Jin Park, Full-Young Chang, Shin Fukudo, Myung-Gyu Choi, Shobna Bhatia, Meiyun Ke, Xiaohua Hou & Michio Hongo. (2010) Asian consensus on irritable bowel syndrome. Journal of Gastroenterology and Hepatology 25:7, pages 1189-1205.
Crossref
Nicholas J. Talley. 2010. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. Sleisenger and Fordtran's Gastrointestinal and Liver Disease 2091 2104.e6 .
Arnold Wald. 2011. Diarrhea. Diarrhea 325 339 .
Brian E. Lacy, Kirsten Weiser & Ryan De Lee. (2009) Review: The treatment of irritable bowel syndrome. Therapeutic Advances in Gastroenterology 2:4, pages 221-238.
Crossref
Takuya Hirata, Toshiyuki Funatsu, Yoshihiro Keto, Shinobu Akuzawa, Hiraku Akiho, Akito Nishida, Masao Sasamata & Keiji Miyata. (2009) Pharmacological and clinical profile of ramosetron hydrochloride (Irribow®), a novel therapeutic agent for irritable bowel syndrome with diarrhea. Folia Pharmacologica Japonica 133:5, pages 281-291.
Crossref
Viola Andresen, Victor M. Montori, Jutta Keller, Colin P. West, Peter Layer & Michael Camilleri. (2008) Effects of 5-Hydroxytryptamine (Serotonin) Type 3 Antagonists on Symptom Relief and Constipation in Nonconstipated Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Clinical Gastroenterology and Hepatology 6:5, pages 545-555.
Crossref
Christopher W Hammerle & Christina M Surawicz. (2008) Updates on treatment of irritable bowel syndrome. World Journal of Gastroenterology 14:17, pages 2639.
Crossref
Tom Kraft & David Kraft. (2007) Irritable bowel syndrome: symptomatic treatment versus integrative psychotherapy. Contemporary Hypnosis 24:4, pages 161-177.
Crossref
. 2006. Wiley Handbook of Current and Emerging Drug Therapies. Wiley Handbook of Current and Emerging Drug Therapies.
C. L. FRISSORA & B. D. CASH. (2007) Review article: the role of antibiotics vs. conventional pharmacotherapy in treating symptoms of irritable bowel syndrome. Alimentary Pharmacology & Therapeutics 25:11, pages 1271-1281.
Crossref
Michael J.G. Farthing. (2007) The patient with refractory diarrhoea. Best Practice & Research Clinical Gastroenterology 21:3, pages 485-501.
Crossref
Fermín Mearin. (2007) Tratamiento farmacológico del síndrome del intestino irritable: una necesidad no cubierta. Gastroenterología y Hepatología 30:3, pages 130-137.
Crossref
M. A. KAMM, C. C. JORDAN, B. R. LEAKER, F. B. NICHOLSON, C. D. R. MURRAY, S. TAYLOR, M. MARSHALL, A. GIBBS, E. G. CARTER & A. V. EMMANUEL. (2007) Pharmacological modulation of gut mucosal and large vessel blood flow. Alimentary Pharmacology & Therapeutics 25:6, pages 693-702.
Crossref
Revital Kariv, Elisa Tiomny, Roman Grenshpon, Roy Dekel, Galit Waisman, Yehuda Ringel & Zamir Halpern. (2006) Low-Dose Naltreoxone for the Treatment of Irritable Bowel Syndrome: A Pilot Study. Digestive Diseases and Sciences 51:12, pages 2128-2133.
Crossref
Mihaela Podovei & Braden Kuo. (2006) Irritable Bowel Syndrome: A Practical Review. Southern Medical Journal 99:11, pages 1235-1242.
Crossref
H. Mönnikes, M. Schmidtmann & I. R. van der Voort. (2006) Arzneimitteltherapie des ReizdarmsyndromsDrug therapy for irritable bowel syndrome. Der Internist 47:10, pages 1073-1083.
Crossref
Susan Roberts & Mary Krystofiak Russell. 2006. Integrating Therapeutic and Complementary Nutrition. Integrating Therapeutic and Complementary Nutrition.
Wai K Leung, Justin CY Wu, SM Liang, LS Chan, Francis KL Chan, He Xie, Sara SL Fung, Aric J Hui, Vincent WS Wong, Chun-Tao Che & Joseph JY Sung. (2006) Treatment of Diarrhea-Predominant Irritable Bowel Syndrome with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Trial. The American Journal of Gastroenterology 101:7, pages 1574-1580.
Crossref
J. TACK, M. FRIED, L. A. HOUGHTON, J. SPICAK & G. FISHER. (2006) Systematic review: the efficacy of treatments for irritable bowel syndrome - a European perspective. Alimentary Pharmacology and Therapeutics 24:2, pages 183-205.
Crossref
Howard Y. Chang, Eoin C. Kelly & Anthony J. Lembo. (2006) Current gut-directed therapies for irritable bowel syndrome. Current Treatment Options in Gastroenterology 9:4, pages 314-323.
Crossref
Michael J. G. Farthing. (2005) Functional diarrhea. Current Gastroenterology Reports 7:5, pages 350-357.
Crossref
. (2005) Directive clinique de consensus pour la prise en charge de la douleur pelvienne chronique. Journal of Obstetrics and Gynaecology Canada 27:8, pages 802-826.
Crossref
. (2005) Consensus Guidelines for the Management of Chronic Pelvic Pain. Journal of Obstetrics and Gynaecology Canada 27:8, pages 781-801.
Crossref
s. m. patel, w. b. stason, a. legedza, s. m. ock, t. j. kaptchuk, l. conboy, k. canenguez, j. k. park, e. kelly, e. jacobson, c. e. kerr & a. j. lembo. (2005) The placebo effect in irritable bowel syndrome trials: a meta-analysis1. Neurogastroenterology and Motility 17:3, pages 332-340.
Crossref
Philip Schoenfeld. (2005) Efficacy of Current Drug Therapies in Irritable Bowel Syndrome: What Works and Does Not Work. Gastroenterology Clinics of North America 34:2, pages 319-335.
Crossref
S. D. Kuiken, G. N. Tytgat & G. E. Boeckxstaens. (2005) Review article: drugs interfering with visceral sensitivity for the treatment of functional gastrointestinal disorders - the clinical evidence. Alimentary Pharmacology and Therapeutics 21:6, pages 633-651.
Crossref
D. Lesbros‐Pantoflickova, P. Michetti, M. Fried, C. Beglinger & A. L. Blum. (2004) Meta‐analysis: the treatment of irritable bowel syndrome. Alimentary Pharmacology & Therapeutics 20:11-12, pages 1253-1269.
Crossref
Michael J.G. Farthing. (2004) Treatment options in irritable bowel syndrome. Best Practice & Research Clinical Gastroenterology 18:4, pages 773-786.
Crossref
Robin Spiller. 2004. Pathophysiology of the Enteric Nervous System. Pathophysiology of the Enteric Nervous System 188 200 .
Nicholas J. Talley. (2003) Evaluation of drug treatment in irritable bowel syndrome. British Journal of Clinical Pharmacology 56:4, pages 362-369.
Crossref
Driss Berrada, Katia Canenguez & Tony Lembo. (2003) New approaches to the medical treatment of irritable bowel syndrome. Current Gastroenterology Reports 5:4, pages 337-342.
Crossref
Fred M. Howard. (2003) Chronic Pelvic Pain. Obstetrics & Gynecology 101:3, pages 594-611.
Crossref
Amir Garakani, Terrance Win, Subhdeep Virk, Sanjay Gupta, David Kaplan & Prakash S. Masand. (2003) Comorbidity of Irritable Bowel Syndrome in Psychiatric Patients: A Review. American Journal of Therapeutics 10:1, pages 61-67.
Crossref
J. G. Rosemore & Brian E. Lacy. (2002) Irritable Bowel Syndrome. Journal of Clinical Gastroenterology 35:Supplement, pages S37-S44.
Crossref
Michael A Pezzone & Arnold Wald. (2002) Functional bowel disorders in inflammatory bowel disease. Gastroenterology Clinics of North America 31:1, pages 347-357.
Crossref
Richard B Birrer. (2002) Irritable bowel syndrome. Disease-a-Month 48:2, pages 101-143.
Crossref
Michael Camilleri. (2001) Management of the irritable bowel syndrome. Gastroenterology 120:3, pages 652-668.
Crossref
Rebecca C. Dunphy & G. Nicholas Verne. (2001) Drug Treatment Options for Irritable Bowel Syndrome. Drugs & Aging 18:3, pages 201-211.
Crossref
Robin D. Rothstein. (2000) IRRITABLE BOWEL SYNDROME. Medical Clinics of North America 84:5, pages 1247-1257.
Crossref
G. Ragnarsson & G. Bodemar. (2001) Treatment of irritable bowel syndrome with loperamide oxide. An open study to determine optimal dosage. Journal of Internal Medicine 248:2, pages 165-166.
Crossref
Shannon M. Turner, Joan E. Stewart, Jenny J. Alexopulos & Jimmie S. Hill. (2000) Irritable bowel syndrome. Current Review of Pain 4:1, pages 54-59.
Crossref
Jeffrey L Jackson, Patrick G O’Malley, Glen Tomkins, Erin Balden, James Santoro & Kurt Kroenke. (2000) Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis11The opinions in this article represent those of the authors and are not to be construed, in any way, to represent those of the U.S. Army or the Department of Defense.. The American Journal of Medicine 108:1, pages 65-72.
Crossref
NICHOLAS J. TALLEY & NATASHA KOLOSKI. 2000. Women and Health. Women and Health 1098 1109 .
Robin C Spiller. (1999) Problems and challenges in the design of irritable bowel syndrome clinical trials: experience from published trials. The American Journal of Medicine 107:5, pages 91-97.
Crossref

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