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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 9
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General Xenobiochemistry

Evaluation of cytochrome P450 inductions by anti-epileptic drug oxcarbazepine, 10-hydroxyoxcarbazepine, and carbamazepine using human hepatocytes and HepaRG cells

Ikuo SugiyamaDepartment of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, ;Drug Metabolism and Pharmacokinetics, Novartis Pharma K.K., Tokyo, Japan, Correspondence[email protected]
,
Norie MurayamaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan, and
,
Ayaka KurokiDepartment of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan,
,
Jagannath KotaDrug Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, Hyderabad, Andhra Pradesh, India
,
Shunsuke IwanoDrug Metabolism and Pharmacokinetics, Novartis Pharma K.K., Tokyo, Japan, ;Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan, and
,
Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Tokyo, Japan, and
&
Takashi HirotaDepartment of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan,
show all
Pages 765-774 | Received 08 Sep 2015, Accepted 08 Nov 2015, Published online: 29 Dec 2015

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Weixuan Zhao & Hongmei Meng. (2022) Effects of genetic polymorphism of drug-metabolizing enzymes on the plasma concentrations of antiepileptic drugs in Chinese population. Bioengineered 13:3, pages 7709-7745.
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