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Xenobiotica
the fate of foreign compounds in biological systems
Volume 9, 1979 - Issue 3
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Original Article

Glutathione conjugation in the detoxication of (Z)-1,3-dichloropropene (a component of the nematocide D-D) in the rat

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Pages 149-156 | Received 13 Aug 1978, Published online: 30 Sep 2009

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M. J. Bartels, S. C. Hansen, C. M. Thornton, K. A. Brzak, A. L. Mendrala, F. K. Dietz & P. J. Kastl. (2004) Pharmacokinetics and metabolism of 14C-1,3-dichloropropene in the Fischer 344 rat and the B6C3F1 mouse. Xenobiotica 34:2, pages 193-213.
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K. A. Richardson, V. T. Edwards, B. C. Jones & D. H. Hutson. (1991) Metabolism in the rat of a model xenobiotic plant metabolite S-benzyl-N-malonyl-L-cysteine. Xenobiotica 21:3, pages 371-382.
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. (1990) Letters to the Editors. Archives of Environmental Health: An International Journal 45:4, pages 248-255.
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JohnD. Osterloh, Rhoda Wang, Frank Schneider & Keith Maddy. (1989) Biological Monitoring of Dichloropropene: Air Concentrations, Urinary Metabolite, and Renal Enzyme Excretion. Archives of Environmental Health: An International Journal 44:4, pages 207-213.
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GregoryD. Fisher & WendellW. Kilgore. (1988) Tissue levels of glutathione following acute inhalation of 1,3‐dichloropropene. Journal of Toxicology and Environmental Health 23:2, pages 171-182.
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WilliamN. Albrecht. (1987) Toxicology and Hazard Assessment of 1,3-Dichloropropene (Telone® II). Archives of Environmental Health: An International Journal 42:5, pages 292-296.
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JohnD. Osterloh, Ben-Sion Cohen, William Popendorf & SusanM. Pond. (1984) Urinary Excretion of the N-Acetyl Cysteine Conjugate of Cis-1,3-Dichloropropene by Exposed Individuals. Archives of Environmental Health: An International Journal 39:4, pages 271-275.
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C. M. Parker, W. B. Coate & R. W. Voelker. (1982) Subchronic inhalation toxicity of 1,3‐dichloropropene/1,2‐dichloropropane (D‐D) in mice and rats. Journal of Toxicology and Environmental Health 9:5-6, pages 899-910.
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A. R. Jones & Jennifer Gibson. (1980) 1,2-Dichloropropane: metabolism and fate in the rat. Xenobiotica 10:11, pages 835-846.
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Articles from other publishers (28)

Michael J Bartels, Michael J Hackett, Matthew W Himmelstein, John W Green, Carl Walker, Claire Terry, Reza Rasoulpour, Mary Challender & Zhongyu (June) Yan. (2020) Metabolic Basis for Nonlinearity in 1,3-Dichloropropene Toxicokinetics and Use in Setting a Kinetically-derived Maximum Inhalation Exposure Concentration in Mice. Toxicological Sciences 174:1, pages 16-24.
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Peixin Tang & Gang Sun. (2018) Highly sensitive colorimetric paper sensor for methyl isothiocyanate (MITC): Using its toxicological reaction. Sensors and Actuators B: Chemical 261, pages 178-187.
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Fiorella Belpoggi, D. Chiozzotto & M. Lauriola. 2003. Patty's Toxicology. Patty's Toxicology 129 229 .
W.T. Stott & B.B. Gollapudi. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 2281 2292 .
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Courtney A. Granville, Matthew K. Ross, Rogelio Tornero-Velez, Nancy M. Hanley, Rachel D. Grindstaff, Avram Gold, Ann M. Richard, Kunihiro Funasaka, Alan H. Tennant, Andrew D. Kligerman, Marina V. Evans & David M. DeMarini. (2005) Genotoxicity and metabolism of the source-water contaminant 1,1-dichloropropene: activation by GSTT1-1 and structure–activity considerations. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 572:1-2, pages 98-112.
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Mutsuko HIRATA-KOIZUMI, Osamu KUSUOKANobuo NISHIMURAHajime WADAHidehiro OGATANaemi FUKUDA, Yoshihiko ITO, Eiichi KAMATA, Makoto EMA & Ryuichi HASEGAWA. (2005) SUSCEPTIBILITY OF NEWBORN RATS TO HEPATOTOXICITY OF 1,3-DIBROMOPROPANE AND 1,1,2,2-TETRABROMOETHANE, COMPARED WITH YOUNG RATS. The Journal of Toxicological Sciences 30:1, pages 29-42.
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W.T. Stott & B.B. Gollapudi. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 1849 1859 .
William T. Stott, B. Bhaskar Gollapudi & K. S. Rao. 2001. Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology 1 42 .
Livia Secondin, Stefano Maso & Andrea Trevisan. (2016) Different effects of (CIS+TRANS) 1,3-dichloropropene in renal cortical slices derived from male and female rats. Human & Experimental Toxicology 18:2, pages 106-110.
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B. Bhaskar Gollapudi, Frank S. Cieszlak, Susan J. Day & Edward W. Carney. (1998) Dominant lethal test with rats exposed to 1,3-dichloropropene by inhalation. Environmental and Molecular Mutagenesis 32:4, pages 351-359.
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J. Meulenbelt. 1996. Human Toxicology. Human Toxicology 561 576 .
R. T. H. van Welie, P. van Duyn, D. H. Brouwer, J. J. van Hemmen, E. J. Brouwer & N. P. E. Vermeulen. (1991) Inhalation exposure to 1,3-dichloropropene in the Dutch flower-bulb culture. Part II. Biological monitoring by measurement of urinary excretion of two mercapturic acid metabolites. Archives of Environmental Contamination and Toxicology 20:1, pages 6-12.
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R.T.H. Van Welie, P. Van Duyn & N.P.E. Vermeulen. (1989) Determination of two mercapturic acid metabolites of 1,3-dichloropropene in human urine with gas chromatography and sulphur-selective detection. Journal of Chromatography B: Biomedical Sciences and Applications 496, pages 463-471.
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Elizabeth K. Weisburger. 1989. The Pathobiology of Neoplasia. The Pathobiology of Neoplasia 39 56 .
W. Onkenhout, P. P. J. Mulder, P. J. Boogaard, W. Buijs & N. P. E. Vermeulen. (1986) Identification and quantitative determination of mercapturic acids formed from Z- and E-1,3-dichloropropene by the rat, using gas chromatography with three different detection techniques. Archives of Toxicology 59:4, pages 235-241.
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W.T. Stott & P.E. Kastl. (1986) Inhalation pharmacokinetics of technical grade 1,3-dichloropropene in rats. Toxicology and Applied Pharmacology 85:3, pages 332-341.
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James A. Bond, Alan R. Dahl, Rogene F. Henderson, John S. Dutcher, Joe L. Mauderly & Linda S. Birnbaum. (1986) Species differences in the disposition of inhaled butadiene. Toxicology and Applied Pharmacology 84:3, pages 617-627.
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K.R. Krijgsheld & A. van der Gen. (1986) Assessment of the impact of the emission of certain organochlorine compounds on the aquatic environment. Chemosphere 15:7, pages 861-880.
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Raymond S. H. Yang. 1986. Residue Reviews. Residue Reviews 19 35 .
James A. Bond, Michele A. Medinsky, John S. Dutcher, Rogene F. Henderson, Yung Sun Cheng, James A. Mewhinney & Linda S. Birnbaum. (1985) Disposition and metabolism of 2,3-[14C]dichloropropene in rats after inhalation. Toxicology and Applied Pharmacology 78:1, pages 47-54.
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YIN-TAK WOO, DAVID Y. LAI, JOSEPH C. ARCOS & MARY F. ARGUS. 1985. Aliphatic and Polyhalogenated Carcinogens. Aliphatic and Polyhalogenated Carcinogens 3 414 .
M.A. Medinsky, J.A. Bond, J.S. Dutcher & L.S. Birnbaum. (1984) Disposition of [14C]2,3-dichloropropene in Fischer-344 rats after oral or intraperitoneal administration. Toxicology Letters 23:1, pages 119-125.
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C.L. Creedy, T.M. Brooks, B.J. Dean, D.H. Hutson & A.S. Wright. (1984) The protective action of glutathione on the microbial mutagenicity of the Z- and E-isomers of 1,3-dichloropropene. Chemico-Biological Interactions 50:1, pages 39-48.
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Joseph Santodonato, Patrick R. Durkin, Michael W. Neal, Frederick Stoss & D.Anthony Gray. (1984) Antimutagenic effect of rat small intestine in vitro on 1,1,2,3-tetrachloropropene and 1,1,2,3,3-pentachloropropene. Cancer Letters 22:3, pages 305-314.
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David H. Hutson. 1983. Mode of Action, Metabolism and Toxicology. Mode of Action, Metabolism and Toxicology 263 274 .
M.W. ANDERS. 1982. Metabolic Basis of Detoxication. Metabolic Basis of Detoxication 29 49 .
A.S. Wright. (1980) The role of metabolism in chemical mutagenesis and chemical carcinogenesis. Mutation Research/Reviews in Genetic Toxicology 75:2, pages 215-241.
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