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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 1
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Research Article

Steric factors in the pharmacokinetics of lindane and α-hexachlorocyclohexane in rats

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Pages 65-77 | Received 17 May 1979, Published online: 22 Sep 2008

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R. N. Khanna, G. S. D. Gupta & M. Anand. (1999) Distribution and isomerization of Hch‐isomers in rats. Toxicological & Environmental Chemistry 71:1-2, pages 149-157.
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R. N. Khanna, R. Gupta, G. S. D. Gupta & M. Anand. (1995) Toxicokinetics and tissue distribution of HCH in rats fed on protein deficient diet. Toxicological & Environmental Chemistry 48:3-4, pages 135-143.
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Padmakar G. Deo, N. Ganesh Karanth, N. Gopalakrishna & K. Karanth. (1994) Biodegradation of Hexachlorocyclohexane Isomers in Soil and Food Environment. Critical Reviews in Microbiology 20:1, pages 57-78.
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R. N. Khanna, Rashmi Gupta, A. Siddiqui, G. S. D. Gupta, S. P. Srivastava & Ravi Shanker. (1992) Hexachlorocyclohexane (HCH) induced changes in microsomal drug metabolizing enzymes and liver lipids in rats fed different levels of protein. Toxicological & Environmental Chemistry 35:3-4, pages 185-196.
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R. N. Khanna, N. Varma, R. Gupta, G. S. D. Gupta & P. K. Ray. (1989) Effects of hexachlorocyclohexane administration on distribution of trace metals in rat tissues. Toxicological & Environmental Chemistry 19:1-2, pages 57-61.
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J. Portig, K. Stein & H. W. Vohland. (1989) Preferential distribution of α-hexachlorocyclohexane into cerebral white matter. Xenobiotica 19:1, pages 123-130.
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R. M. Macholz, R. Knoll, H.-J. Lewerenz, M. Petrzika & R. Engst. (1982) Metabolism of α-hexachlorocyclohexane. Free metabolites in urine and organs of rats. Xenobiotica 12:4, pages 227-231.
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J. F. Fitzloff, J. Portig & K. Stein. (1982) Lindane metabolism by human and rat liver microsomes†. Xenobiotica 12:3, pages 197-202.
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J.P. Lay, W. Klein, F. Korte & E. Richter. (1981) Metabolism of ß‐hexachlorocyclohexane‐14C in rats following low dosing in the daily diet. Journal of Environmental Science and Health, Part B 16:3, pages 227-238.
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Edward L. Croom, Timothy J. Shafer, Marina V. Evans, William R. Mundy, Chris R. Eklund, Andrew F.M. Johnstone, Cina M. Mack & Rex A. Pegram. (2015) Improving in vitro to in vivo extrapolation by incorporating toxicokinetic measurements: A case study of lindane-induced neurotoxicity. Toxicology and Applied Pharmacology 283:1, pages 9-19.
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Andrew G Smith. 2012. Mammalian Toxicology of Insecticides. Mammalian Toxicology of Insecticides 37 103 .
Mattias Öberg, Natalia Stern, ören Jensen, Clas Wesén, Peter Haglund, Helena Casabona, Niklas Johansson, Kajsa Blomgren & Helen Håkansson. (2003) Subchronic Toxicity of Baltic Herring Oil and its Fractions in the Rat I: Fractionation and Levels of Organohalogen Pollutants. Pharmacology & Toxicology 91:5, pages 220-231.
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Hana R. Pohl & Carolyn A. Tylenda. (2016) Breast-feeding exposure of infants to selected pesticides: a public health viewpoint. Toxicology and Industrial Health 16:2, pages 65-77.
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Joost DeJongh & Bas J Blaauboer. (1997) Simulation of lindane kinetics in rats. Toxicology 122:1-2, pages 1-9.
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PR Dalsenter, AS Faqi, J. Webb, H-J. Merker & I. Chahoud. (2016) Reproductive toxicity and toxicokinetics of lindane in the male offspring of rats exposed during lactation. Human & Experimental Toxicology 16:3, pages 146-153.
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M.E. Gilbert. (1995) Repeated exposure to lindane leads to behavioral sensitization and facilitates electrical kindling. Neurotoxicology and Teratology 17:2, pages 131-141.
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J.A. Pulido, N. del Hoyo & M.A. Pérez-Albarsanz. (1992) The effects of different hexachlorocyclohexanes and cyclodienes on glucose uptake and inositol phospholipid synthesis in rat brain cortex. Life Sciences 50:21, pages 1585-1596.
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Luis A. Videla, Silvia B.M. Barros & Virginia B.C. Junqueira. (1990) Lindane-induced liver oxidative stress. Free Radical Biology and Medicine 9:2, pages 169-179.
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. 1989. Metabolic Maps of Pesticides. Metabolic Maps of Pesticides 244 255 .
J. Portig & C. Schnorr. (1988) The potency of gamma-1,2,3,4,5,6-hexachlorocyclohexane (lindane). Toxicology 52:3, pages 309-321.
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Coral Sanfeliu, Lluïsa Camón, Emili Martínez, Carme Solà, Francesc Artigas & Eduard Rodríguez-Farré. (1988) Regional distribution of lindane in rat brain. Toxicology 49:1, pages 189-196.
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J. M. Tusell, C. Su�ol, E. Gelp� & E. Rodr�guez-Farr�. (1987) Relationship between lindane concentration in blood and brain and convulsant response in rats after oral or intraperitoneal administration. Archives of Toxicology 60:6, pages 432-437.
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W. Bursch, B. D�sterberg & R. Schulte-Hermann. (1986) Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate. Archives of Toxicology 59:4, pages 221-227.
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R. M. Macholz & M. Kujawa. 1985. Residue Reviews. Residue Reviews 119 149 .
J.M. Yvenlin, C. Yvelin & M. Lievremont. (1984) Uptake of [U-14C]Lindane (γ-hexachlorocyclohexane) following exposure of isolated hepatocytes for short intervals of time. Pesticide Biochemistry and Physiology 22:3, pages 349-359.
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J. Portig. 1983. Mode of Action, Metabolism and Toxicology. Mode of Action, Metabolism and Toxicology 401 405 .
H.W. Vohland, J. Portig & K. Stein. (1981) Neuropharmacological effects of isomers of hexachlorocyclohexane. Toxicology and Applied Pharmacology 57:3, pages 425-438.
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K. Baumann, J. Angerer, R. Heinrich & G. Lehnert. (1980) Occupational exposure to hexachlorocyclohexane. International Archives of Occupational and Environmental Health 47:2, pages 119-127.
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