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Acta Oncologica Volume 54, 2015 - Issue 9
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ORIGINAL ARTICLE

Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure

Sebastian ZschaeckDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;German Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, GermanyCorrespondence[email protected]
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Robert HaaseOncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany
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Nasreddin AbolmaaliOncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Department of Radiology, Medical Faculty and University Hospital Carl Gustav Carus, Dresden, Germany
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Rosalind PerrinOncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Paul Scherrer Institute, Villigen, Switzerland
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Kristin StützerOncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany
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Steffen AppoldDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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Jörg SteinbachInstitute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Germany
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Jörg KotzerkeGerman Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Department of Nuclear Medicine, Medical Faculty and University Hospital Carl Gustav Carus, Dresden, Germany
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Daniel ZipsDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;German Cancer Consortium (DKTK), Tübingen, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Tübingen, Germany
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Christian RichterDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;German Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Germany
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Volker GudziolDepartment of Otorhinolaryngology, Medical Faculty and University Hospital Carl Gustav Carus, Dresden, Germany
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Mechthild KrauseDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;German Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Germany
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Klaus ZöphelGerman Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Department of Nuclear Medicine, Medical Faculty and University Hospital Carl Gustav Carus, Dresden, Germany
&
Michael BaumannDepartment of Radiation Oncology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany;German Cancer Consortium (DKTK), Dresden, Germany, and German Cancer Research Center (DKFZ)Heidelberg, Germany;OncoRay – National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Germany;Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Germany
 show all
Pages 1355-1363 | Received 07 Apr 2015, Accepted 16 Jul 2015, Published online: 23 Sep 2015

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Mireia Crispin-Ortuzar, Aditya Apte, Milan Grkovski, Jung Hun Oh, Nancy Y. Lee, Heiko Schöder, John L. Humm & Joseph O. Deasy. (2018) Predicting hypoxia status using a combination of contrast-enhanced computed tomography and [18F]-Fluorodeoxyglucose positron emission tomography radiomics features. Radiotherapy and Oncology 127:1, pages 36-42.
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Annette M. Lim, Quynh-Thu Le & Danny Rischin. 2018. Molecular Determinants of Head and Neck Cancer. Molecular Determinants of Head and Neck Cancer 397 438 .
Tanuj Puri, Tessa A. Greenhalgh, James M. Wilson, Jamie Franklin, Lia Mun Wang, Victoria Strauss, Chris Cunningham, Mike Partridge & Tim Maughan. (2017) [18F]Fluoromisonidazole PET in rectal cancer. EJNMMI Research 7:1.
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Esther G. C. Troost, Lydia Koi, Ala Yaromina & Mechthild Krause. (2017) Therapeutic options to overcome tumor hypoxia in radiation oncology. Clinical and Translational Imaging 5:5, pages 455-464.
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Florence Colliez, Bernard Gallez & Bénédicte F. Jordan. (2017) Assessing Tumor Oxygenation for Predicting Outcome in Radiation Oncology: A Review of Studies Correlating Tumor Hypoxic Status and Outcome in the Preclinical and Clinical Settings. Frontiers in Oncology 7.
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L. J. Wack, D. Mönnich, A. Yaromina, D. Zips, M. Baumann & D. Thorwarth. (2016) Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O 2 consumption? . Medical Physics 43:7, pages 4113-4121.
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Annika Jakobi, Armin Lühr, Kristin Stützer, Anna Bandurska-Luque, Steffen Löck, Mechthild Krause, Michael Baumann, Rosalind Perrin & Christian Richter. (2015) Increase in Tumor Control and Normal Tissue Complication Probabilities in Advanced Head-and-Neck Cancer for Dose-Escalated Intensity-Modulated Photon and Proton Therapy. Frontiers in Oncology 5.
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