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Original Article

Mechanism of Action of Anti-Inflammatory Drugs

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Pages 9-21 | Published online: 12 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Wissam H. Faour, Mohamed Mroueh, Costatantine F. Daher, Rasha Y. Elbayaa, Hanan M. Ragab, Asser I. Ghoneim, Ahmed I. El-mallah & Hayam M. A. Ashour. (2016) Synthesis of some new amide-linked bipyrazoles and their evaluation as anti-inflammatory and analgesic agents. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1079-1094.
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Denish Mika & C. Guruvayoorappan. (2013) Experimental study on anti-tumor and anti-inflammatory effect of Thespesia populnea phytochemical extract in mice models. Immunopharmacology and Immunotoxicology 35:1, pages 157-163.
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Tong J. Gan. (2010) Diclofenac: an update on its mechanism of action and safety profile. Current Medical Research and Opinion 26:7, pages 1715-1731.
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Fumiaki Kojima, Mohit Kapoor, Shinichi Kawai & Leslie J Crofford. (2006) New insights into eicosanoid biosynthetic pathways: implications for arthritis. Expert Review of Clinical Immunology 2:2, pages 277-291.
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V. Kothekar, Shakti Sahi & M. Srinivasan. (1999) Computer Simulation of the Interaction of Non-steroidal Anti-inflammatory Drugs: Indoprofen and NS398 with Cyclooxygenase. Journal of Biomolecular Structure and Dynamics 16:4, pages 901-915.
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Christina Gustafson-svärd, Ingela Lilja, Olof Hallböök & Rune Sjödahl. (1997) Cyclo-oxygenase and Colon Cancer: Clues to the Aspirin Effect?. Annals of Medicine 29:3, pages 247-252.
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K. Beddar, A. Bouchoucha, M. A. Bourouai, S. Zaater & S. Djebbar. (2023) Transition Metal Complexes of 2-Aminopyridine Derivatives as Cyclooxygenase Inhibitors: Stability, Spectral, and Thermal Characterization, Electrochemical Behavior, DFT Calculations, Molecular Docking, and Biological Activities. Russian Journal of General Chemistry 93:10, pages 2578-2599.
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Rahul D. Kamble, Rohan J. Meshram, Shrikant V. Hese, Rahul A. More, Sonali S. Kamble, Rajesh N. Gacche & Bhaskar S. Dawane. (2016) Synthesis and in silico investigation of thiazoles bearing pyrazoles derivatives as anti-inflammatory agents. Computational Biology and Chemistry 61, pages 86-96.
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Jaime Ribeiro-Filho, Márcia Piuvezam & Patrícia Bozza. (2015) Anti-Allergic Properties of Curine, a Bisbenzylisoquinoline Alkaloid. Molecules 20:3, pages 4695-4707.
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Anna H. Le, Luis A. Bonachea & Shelley L. Cargill. (2014) Meloxicam and Buprenorphine Treatment after Ovarian Transplantation Does Not Affect Estrous Cyclicity and Follicular Integrity in Aged CBA/J Mice. PLoS ONE 9:8, pages e106013.
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Mahesh B. Palkar, Anuj S. Singhai, Pradeepkumar M. Ronad, A.H.M. Vishwanathswamy, Thippeswamy S. Boreddy, Veeresh P. Veerapur, Mahamadhanif S. Shaikh, Rajesh A. Rane & Rajshekhar Karpoormath. (2014) Synthesis, pharmacological screening and in silico studies of new class of Diclofenac analogues as a promising anti-inflammatory agents. Bioorganic & Medicinal Chemistry 22:10, pages 2855-2866.
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Abdulaziz AlmaawiHong Tian WangOvidiu CiobanuSora A.L. RowasSonia RampersadJohn AntoniouFackson Mwale. (2013) Effect of Acetaminophen and Nonsteroidal Anti-Inflammatory Drugs on Gene Expression of Mesenchymal Stem Cells. Tissue Engineering Part A 19:7-8, pages 1039-1046.
Crossref
Patricia A. Talcott & Sharon M. Gwaltney-Brant. 2013. Small Animal Toxicology. Small Animal Toxicology 687 708 .
Alka Bali, Sabrinjit Kaur Dhillon & Chandrasekaran Balakumar. (2011) Alkoxyphenyl methanesulfonamides: synthesis, anti-inflammatory effect, and docking studies. Medicinal Chemistry Research 21:10, pages 3053-3062.
Crossref
Jin Cai, Yanbing Duan, Jia Yu, Junqing Chen, Meng Chao & Min Ji. (2012) Bone-targeting glycol and NSAIDS ester prodrugs of rhein: Synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies. European Journal of Medicinal Chemistry 55, pages 409-419.
Crossref
Babasaheb P. Bandgar, Laxman K. Adsul, Hemant V. Chavan, Shivkumar S. Jalde, Sadanand N. Shringare, Rafique Shaikh, Rohan J. Meshram, Rajesh N. Gacche & Vijay Masand. (2012) Synthesis, biological evaluation, and docking studies of 3-(substituted)-aryl-5-(9-methyl-3-carbazole)-1H-2-pyrazolines as potent anti-inflammatory and antioxidant agents. Bioorganic & Medicinal Chemistry Letters 22:18, pages 5839-5844.
Crossref
Babasaheb P. Bandgar, Baliram S. Hote, Nagesh A. Dhole & Rajesh N. Gacche. (2011) Synthesis and biological evaluation of novel series of chalcone derivatives as inhibitors of cyclooxygenase and LPS-induced TNF-α with potent antioxidant properties. Medicinal Chemistry Research 21:9, pages 2292-2299.
Crossref
Wei Liu, Yong Zhang & Bing Zhao. (2012) Structural Studies for Specific Binding Capacity of β‐Cyclodextrin with Ibuprofen. Journal of the Chinese Chemical Society 59:9, pages 1155-1158.
Crossref
Mario I. Ortiz, Gilberto Castañeda-Hernández, Jeannett A. Izquierdo-Vega, Manuel Sánchez-Gutiérrez, Héctor A. Ponce-Monter & Vinicio Granados-Soto. (2012) Role of ATP-sensitive K+ channels in the antinociception induced by non-steroidal anti-inflammatory drugs in streptozotocin-diabetic and non-diabetic rats. Pharmacology Biochemistry and Behavior 102:1, pages 163-169.
Crossref
Ito L. Barroso-Neto, João Paulo C. Marques, Roner F. da Costa, Ewerton W. S. Caetano, Benildo S. Cavada, Carmem Gottfried & Valder N. Freire. (2012) Inactivation of Ovine Cyclooxygenase-1 by Bromoaspirin and Aspirin: A Quantum Chemistry Description. The Journal of Physical Chemistry B 116:10, pages 3270-3279.
Crossref
Tatsuya Hoshino, Takushi Namba, Masaya Takehara, Naoya Murao, Takahide Matsushima, Yukihiko Sugimoto, Shuh Narumiya, Toshiharu Suzuki & Tohru Mizushima. (2012) Improvement of cognitive function in Alzheimer’s disease model mice by genetic and pharmacological inhibition of the EP 4 receptor . Journal of Neurochemistry 120:5, pages 795-805.
Crossref
Alka Bali, Ruchika Ohri & Pran Kishore Deb. (2012) Synthesis, evaluation and docking studies on 3-alkoxy-4-methanesulfonamido acetophenone derivatives as non ulcerogenic anti-inflammatory agents. European Journal of Medicinal Chemistry 49, pages 397-405.
Crossref
Sarah Jefferies, Manoj Saxena & Paul Young. (2012) Paracetamol in critical illness: a review. Critical Care and Resuscitation 14:1, pages 74-80.
Crossref
N. Sethi, A. Anand, K. K. Chandrul, G. Jain & K. S. Srinivas. (2012) Development and Validation of a Stability-Indicating RP-UPLC Method for the Quantitative Analysis of Nabumetone in Tablet Dosage Form. Journal of Chromatographic Science 50:2, pages 85-90.
Crossref
Christi Brewer & Dwight Waddell. (2012) The Role of Prostaglandin F<sub>2α</sub> in Skeletal Muscle Regeneration. Journal of Trainology 1:2, pages 45-52.
Crossref
Lee-Shuan LIN, Yuko KAYASUGA, Nobuyuki SHIMOHATA, Hiroyuki KAMATA, Shigeki SUZUKI, Ryosuke ECHIGO, Manabu MOCHIZUKI, Ung-Il CHUNG & Nobuo SASAKI. (2012) Lyophilized Aspirin with Trehalose May Decrease the Incidence of Gastric Injuries in Healthy Dogs. Journal of Veterinary Medical Science 74:11, pages 1511-1516.
Crossref
Takafumi SUNAGA, Namgil OH, Kenji HOSOYA, Satoshi TAKAGI & Masahiro OKUMURA. (2012) Pro-Apoptotic Effects of Tepoxalin, a Cyclooxygenase/Lipoxygenase Dual Inhibitor, on Canine Synovial Fibroblasts. Journal of Veterinary Medical Science 74:6, pages 745-750.
Crossref
Mario I. Ortiz. (2012) Metformin and phenformin block the peripheral antinociception induced by diclofenac and indomethacin on the formalin test. Life Sciences 90:1-2, pages 8-12.
Crossref
Khozirah Shaari, Velan Suppaiah, Lam Kok Wai, Johnson Stanslas, Bimo Ario Tejo, Daud Ahmad Israf, Faridah Abas, Intan Safinar Ismail, Nor Hasifi Shuaib, Seema Zareen & Nordin Hj. Lajis. (2011) Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase. Bioorganic & Medicinal Chemistry 19:21, pages 6340-6347.
Crossref
Pushpa Hegde, Mohan S. Maddur, Alain Friboulet, Jagadeesh Bayry & Srini V. Kaveri. (2011) Viscum album Exerts Anti-Inflammatory Effect by Selectively Inhibiting Cytokine-Induced Expression of Cyclooxygenase-2. PLoS ONE 6:10, pages e26312.
Crossref
Mario I. Ortiz. (2011) Blockade of the antinociception induced by diclofenac, but not of indomethacin, by sulfonylureas and biguanides. Pharmacology Biochemistry and Behavior 99:1, pages 1-6.
Crossref
Michal Markiewicz & Marta Pasenkiewicz-Gierula. (2011) Comparative Model Studies of Gastric Toxicity of Nonsteroidal Anti-Inflammatory Drugs. Langmuir 27:11, pages 6950-6961.
Crossref
Young-Oh Shin, Jeong-Beom Lee, Young-Ki Min & Hun-Mo Yang. (2011) Effect of oligonol intake on cortisol and cytokines, and body temperature after leg immersion into hot water. Food Science and Biotechnology 20:3, pages 659-663.
Crossref
Trevor Tanner, Sue Aspley, Andrew Munn & Tracy Thomas. (2010) The pharmacokinetic profile of a novel fixed-dose combination tablet of ibuprofen and paracetamol. BMC Clinical Pharmacology 10:1.
Crossref
Tomoaki Ishihara, Ken-Ichiro Tanaka, Saki Tashiro, Kosuke Yoshida & Tohru Mizushima. (2010) Protective effect of rebamipide against celecoxib-induced gastric mucosal cell apoptosis. Biochemical Pharmacology 79:11, pages 1622-1633.
Crossref
Miyako Kato, Shinichi Nishida, Hidero Kitasato, Natsue Sakata & Shinichi Kawai. (2001) Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. Journal of Pharmacy and Pharmacology 53:12, pages 1679-1685.
Crossref
James H. Shull. 2010. The Essence of Analgesia and Analgesics. The Essence of Analgesia and Analgesics 218 221 .
Eric C. Lin & Shu-ming Wang. 2010. The Essence of Analgesia and Analgesics. The Essence of Analgesia and Analgesics 215 217 .
Kazuhide Higuchi, Eiji Umegaki, Toshio Watanabe, Yukiko Yoda, Eijiro Morita, Mitsuyuki Murano, Satoshi Tokioka & Tetsuo Arakawa. (2009) Present status and strategy of NSAIDs-induced small bowel injury. Journal of Gastroenterology 44:9, pages 879-888.
Crossref
Matthew J. Walters, Anna L. Blobaum, Philip J. Kingsley, Andrew S. Felts, Gary A. Sulikowski & Lawrence J. Marnett. (2009) The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives. Bioorganic & Medicinal Chemistry Letters 19:12, pages 3271-3274.
Crossref
Abhay S. Chauhan, Prakash V. Diwan, Narenda K. Jain & Donald A. Tomalia. (2009) Unexpected In Vivo Anti-Inflammatory Activity Observed for Simple, Surface Functionalized Poly(amidoamine) Dendrimers. Biomacromolecules 10:5, pages 1195-1202.
Crossref
Laurence Maiden. (2009) Capsule endoscopic diagnosis of nonsteroidal antiinflammatory drug-induced enteropathy. Journal of Gastroenterology 44:S19, pages 64-71.
Crossref
Xuezhi Bi, Zhiyun Meng, Hebing Chen, Xiaoxia Zhu & Guifang Dou. (2008) In vivo and in vitro metabolism of lefucoxib in rats. Journal of Pharmaceutical and Biomedical Analysis 48:1, pages 134-139.
Crossref
Zihni Cuneyt Karabuda, Nilufer Bolukbasi, Ali Aral, Cansu Basegmez‐Zeren & Tayfun Ozdemir. (2007) Comparison of Analgesic and Anti‐Inflammatory Efficacy of Selective and Non‐Selective Cyclooxygenase‐2 Inhibitors in Dental Implant Surgery. Journal of Periodontology 78:12, pages 2284-2288.
Crossref
Tatsuya Hoshino, Tadashi Nakaya, Takashi Homan, Ken-ichiro Tanaka, Yukihiko Sugimoto, Wataru Araki, Masami Narita, Shuh Narumiya, Toshiharu Suzuki & Tohru Mizushima. (2007) Involvement of Prostaglandin E2 in Production of Amyloid-β Peptides Both in Vitro and in Vivo. Journal of Biological Chemistry 282:45, pages 32676-32688.
Crossref
Leanne Coyne, Jiping Su, Debra Patten & Robert F. Halliwell. (2007) Characterization of the interaction between fenamates and hippocampal neuron GABAA receptors. Neurochemistry International 51:6-7, pages 440-446.
Crossref
Andrew S. Felts, Chuan Ji, Jennifer B. Stafford, Brenda C. Crews, Philip J. Kingsley, Carol A. Rouzer, Mary Kay Washington, Kotha Subbaramaiah, Brianna S. Siegel, Shiu M. Young, Andrew J. Dannenberg & Lawrence J. Marnett. (2007) Desmethyl Derivatives of Indomethacin and Sulindac as Probes for Cyclooxygenase-Dependent Biology. ACS Chemical Biology 2:7, pages 479-483.
Crossref
I.M.S. Eldeen, F.R. Van Heerden & J. Van Staden. (2007) Biological activities of cycloart-23-ene-3,25-diol isolated from the leaves of Trichilia dregeana. South African Journal of Botany 73:3, pages 366-371.
Crossref
Ennio Esposito, Vincenzo Di Matteo, Arcangelo Benigno, Massimo Pierucci, Giuseppe Crescimanno & Giuseppe Di Giovanni. (2007) Non-steroidal anti-inflammatory drugs in Parkinson's disease. Experimental Neurology 205:2, pages 295-312.
Crossref
Shinji Mima, Hironori Ushijima, Hyun-Jung Hwang, Shinji Tsutsumi, Masaki Makise, Yoshihiro Yamaguchi, Tomofusa Tsuchiya, Hiroshi Mizushima & Tohru Mizushima. (2007) Identification of the TPO1 gene in yeast, and its human orthologue TETRAN, which cause resistance to NSAIDs . FEBS Letters 581:7, pages 1457-1463.
Crossref
Carl D. Bradford, James D. Cotter, Megan S. Thorburn, Robert J. Walker & David F. Gerrard. (2007) Exercise can be pyrogenic in humans. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 292:1, pages R143-R149.
Crossref
John M. Connors. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 11 .
Aryn A. Flood & Kevin T. Fitzgerald. (2006) The Poison-Proof Practice. Clinical Techniques in Small Animal Practice 21:4, pages 164-173.
Crossref
Kevin T. Fitzgerald, Alvin C. Bronstein & Aryn A. Flood. (2006) “Over-The-Counter” Drug Toxicities in Companion Animals. Clinical Techniques in Small Animal Practice 21:4, pages 215-226.
Crossref
Alejandra Picazo, Gilberto Castañeda-Hernández & Mario I. Ortiz. (2006) Examination of the interaction between peripheral diclofenac and gabapentin on the 5% formalin test in rats. Life Sciences 79:24, pages 2283-2287.
Crossref
A.B. Barroso, V. Lima, G.C. Guzzo, R.A. Moraes, M.C. Vasconcellos, M.M. Bezerra, F.A.L. Viana, R.C.R. Bezerra, G.S.M. Santana, F.A. Frota-Bezerra, M.O. Moraes & M.E.A. Moraes. (2006) Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery. Brazilian Journal of Medical and Biological Research 39:9, pages 1241-1247.
Crossref
Shunlai Li & Yan Zheng. (2006) Self-Organizing Molecular Field Analysis on a New Series of COX-2 Selective Inhibitors: 1,5-Diarylimidazoles. International Journal of Molecular Sciences 7:7, pages 220-229.
Crossref
Mingyue Zheng, Zhenshan Zhang, Weiliang Zhu, Hong Liu, Xiaomin Luo, Kaixian Chen & Hualiang Jiang. (2006) Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): Molecular docking and 3D-QSAR analyses on DHDMBF analogues. Bioorganic & Medicinal Chemistry 14:10, pages 3428-3437.
Crossref
Patricia A. Talcott. 2006. Small Animal Toxicology. Small Animal Toxicology 902 933 .
Jorge G. Mogilner, Michael Lurie, Arnold G. Coran, Ofer Nativ, Eitan Shiloni & Igor Sukhotnik. (2005) Effect of diclofenac on germ cell apoptosis following testicular ischemia-reperfusion injury in a rat. Pediatric Surgery International 22:1, pages 99-105.
Crossref
Amit S. Kalgutkar, Brenda C. Crews, Sam Saleh, Daniel Prudhomme & Lawrence J. Marnett. (2005) Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors. Bioorganic & Medicinal Chemistry 13:24, pages 6810-6822.
Crossref
S. MEHTA, I. T. JOHNSON & M. RHODES. (2005) Systematic review: the chemoprevention of oesophageal adenocarcinoma. Alimentary Pharmacology and Therapeutics 22:9, pages 759-768.
Crossref
Ken-ichiro Tanaka, Wataru Tomisato, Tatsuya Hoshino, Tomoaki Ishihara, Takushi Namba, Mayuko Aburaya, Takashi Katsu, Keitarou Suzuki, Shinji Tsutsumi & Tohru Mizushima. (2005) Involvement of Intracellular Ca2+ Levels in Nonsteroidal Anti-inflammatory Drug-induced Apoptosis. Journal of Biological Chemistry 280:35, pages 31059-31067.
Crossref
Hyung-Chahn Lee, In-Chul Park, Myung-Jin Park, Sungkwan An, Sang-Hyeok Woo, Hyeon-Ok Jin, Hee Yong Chung, Su-Jae Lee, Ho-Shin Gwak, Young-Jun Hong, Doo-Hyun Yoo, Chang-Hun Rhee & Seok-Il Hong. (2005) Sulindac and its metabolites inhibit invasion of glioblastoma cells via down-regulation of Akt/PKB and MMP-2. Journal of Cellular Biochemistry 94:3, pages 597-610.
Crossref
Raymond A. Dionne, Duncan Haynes, Jaime S. Brahim, Janet S. Rowan & Pol-Henri Guivarc'h. (2004) Analgesic Effect of Sustained-Release Flurbiprofen Administered at the Site of Tissue Injury in the Oral Surgery Model. The Journal of Clinical Pharmacology 44:12, pages 1418-1424.
Crossref
Wataru Tomisato, Ken-ichiro Tanaka, Takashi Katsu, Hiroki Kakuta, Kenji Sasaki, Shinji Tsutsumi, Tatsuya Hoshino, Mayuko Aburaya, Daiwei Li, Tomofusa Tsuchiya, Keitarou Suzuki, Kazumi Yokomizo & Tohru Mizushima. (2004) Membrane permeabilization by non-steroidal anti-inflammatory drugs. Biochemical and Biophysical Research Communications 323:3, pages 1032-1039.
Crossref
Maykel Pérez González, Luiz Carlos Dias, Aliuska Morales Helguera, Yanisleidy Morales Rodrı́guez, Luciana Gonzaga de Oliveira, Luis Torres Gomez & Humberto Gonzalez Diaz. (2004) TOPS-MODE based QSARs derived from heterogeneous series of compounds. Applications to the design of new anti-inflammatory compounds. Bioorganic & Medicinal Chemistry 12:16, pages 4467-4475.
Crossref
Kwang-Ok Lee, Hyun-Ju Park, Young-Ho Kim, Seung-Yong Seo, Yong-Sil Lee, Sung-Hyun Moon, Nam-Joong Kim, Nam-Song Choi & Young-Ger Suh. (2004) CoMFA and coMSIA 3d qsar studies on pimarane cyclooxygenase-2 (COX-2) inhibitors. Archives of Pharmacal Research 27:5, pages 467-470.
Crossref
Hye-Jung Kim, Chong Hak Chae, Kyu Yang Yi, Kyung-Lae Park & Sung-eun Yoo. (2004) Computational studies of COX-2 inhibitors: 3D-QSAR and docking. Bioorganic & Medicinal Chemistry 12:7, pages 1629-1641.
Crossref
Linda M. Van Hoogmoed, Christiana M. Drake & Jack R. Snyder. (2004) In vitro investigation of the effects of nonsteroidal anti-inflammatory drugs, prostaglandin E2, and prostaglandin F2 on contractile activity of the third compartment of the stomach of llamas. American Journal of Veterinary Research 65:2, pages 220-224.
Crossref
Wataru Tomisato, Shinji Tsutsumi, Tatsuya Hoshino, Hyun-Jung Hwang, Mitsunobu Mio, Tomofusa Tsuchiya & Tohru Mizushima. (2004) Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions. Biochemical Pharmacology 67:3, pages 575-585.
Crossref
Sunil K. Singh, P.Ganapati Reddy, K.Srinivasa Rao, Braj B. Lohray, P. Misra, Shaikh A. Rajjak, Yeleswarapu K. Rao & A. Venkateswarlu. (2004) Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors. Bioorganic & Medicinal Chemistry Letters 14:2, pages 499-504.
Crossref
Marı́a Fernández-Tome, Leticia Kraemer, Sebastián Cembal Federman, Nicolás Favale, Emir Speziale & Norma Sterin-Speziale. (2004) COX-2-mediated PGD2 synthesis regulates phosphatidylcholine biosynthesis in rat renal papillary tissue. Biochemical Pharmacology 67:2, pages 245-254.
Crossref
H.X. Liu, R.S. Zhang, X.J. Yao, M.C. Liu, Z.D. Hu & B.T. Fan. (2004) QSAR and classification models of a novel series of COX-2 selective inhibitors: 1, 5-diarylimidazoles based on support vector machines. Journal of Computer-Aided Molecular Design 18:6, pages 389-399.
Crossref
Melissa K. Reeder, Rifat Pamakcu, I. Bernard Weinstein, Kirk Hoffman & W. Joseph Thompson. 2004. Cancer Chemoprevention. Cancer Chemoprevention 401 416 .
Esther N. Matu & Johannes van Staden. (2003) Antibacterial and anti-inflammatory activities of some plants used for medicinal purposes in Kenya. Journal of Ethnopharmacology 87:1, pages 35-41.
Crossref
Carol A. Rouzer & Lawrence J. Marnett. (2003) Mechanism of Free Radical Oxygenation of Polyunsaturated Fatty Acids by Cyclooxygenases. Chemical Reviews 103:6, pages 2239-2304.
Crossref
Peter Ghosh. (2003) Osteoarthritis: 2002 and beyond. APLAR Journal of Rheumatology 6:1, pages 83-88.
Crossref
J.-C. Schellenberg, A.N. Shelling & C.C. Van Ee. (2003) Activity, synthesis, storage, and messenger RNA of cyclooxygenase in intrauterine tissues of guinea pigs near term and during labor. Prostaglandins, Leukotrienes and Essential Fatty Acids 68:4, pages 291-298.
Crossref
Robert Legenstein, Peter B?sch & Alfred Ungersb?ck. (2003) Indomethacin versus meloxicam for prevention of heterotopic ossification after total hip arthroplasty. Archives of Orthopaedic and Trauma Surgery 123:2-3, pages 91-94.
Crossref
J. Antonio Aldrete. (2003) Epidural Injections of Indomethacin for Postlaminectomy Syndrome: A Preliminary Report. Anesthesia & Analgesia 96:2, pages 463-468.
Crossref
Dana Albert, Ilse Zündorf, Theo Dingermann, Walter E. Müller, Dieter Steinhilber & Oliver Werz. (2002) Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochemical Pharmacology 64:12, pages 1767-1775.
Crossref
Natsuko Kusunoki, Ryuta Yamazaki & Shinichi Kawai. (2002) Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors. Arthritis & Rheumatism 46:12, pages 3159-3167.
Crossref
Marc Pouliot, Marie-Élaine Fiset, Mireille Massé, Paul H. Naccache & Pierre Borgeat. (2002) Adenosine Up-Regulates Cyclooxygenase-2 in Human Granulocytes: Impact on the Balance of Eicosanoid Generation. The Journal of Immunology 169:9, pages 5279-5286.
Crossref
Linda M. Van Hoogmoed, Jack R. Snyder & Faye A. Harmon. (2002) In vitro investigation of the effects of cyclooxygenase-2 inhibitors on contractile activity of the equine dorsal and ventral colon. American Journal of Veterinary Research 63:11, pages 1496-1500.
Crossref
John A Rudd, Kouichi Yamamoto, Atsushi Yamatodani & Noriaki Takeda. (2002) Differential action of ondansetron and dexamethasone to modify cisplatin-induced acute and delayed kaolin consumption (“pica”) in rats. European Journal of Pharmacology 454:1, pages 47-52.
Crossref
Elham Rahme, Dan Pettitt & Jacques LeLorier. (2002) Determinants and sequelae associated with utilization of acetaminophen versus traditional nonsteroidal antiinflammatory drugs in an elderly population. Arthritis & Rheumatism 46:11, pages 3046-3054.
Crossref
Yakdhane Kacem, Jamil Kraiem, Emna Kerkeni, Abderrahman Bouraoui & Béchir Ben Hassine. (2002) Synthesis and pharmacological profile of 6-methyl-3-isopropyl-2H-1,2-benzothiazin-4(3H)-one 1,1-dioxide derivatives: non-steroidal anti-inflammatory agents with reduced ulcerogenic effects in the rat. European Journal of Pharmaceutical Sciences 16:4-5, pages 221-228.
Crossref
Nicolas G Bazan, Vittorio Colangelo & Walter J Lukiw. (2002) Prostaglandins and other lipid mediators in Alzheimer’s disease. Prostaglandins & Other Lipid Mediators 68-69, pages 197-210.
Crossref
W. Stewart Hillis. (2002) Areas of Emerging Interest in Analgesia: Cardiovascular Complications. American Journal of Therapeutics 9:3, pages 259-269.
Crossref
D.Craig Brater. (2002) Renal Effects of Cyclooxygyenase-2-Selective Inhibitors. Journal of Pain and Symptom Management 23:4, pages S15-S20.
Crossref
Gloria P Hernández-Delgadillo, Rosa Ventura Martı́nez, Ma.Irene Dı́az Reval, Adriana M Domı́nguez Ramı́rez & Francisco J López-Muñoz. (2002) Metamizol potentiates morphine antinociception but not constipation after chronic treatment. European Journal of Pharmacology 441:3, pages 177-183.
Crossref
S LIN, M YENPINGKUO, J WANG, J LEE, C WANG, S HUANG, C SHUN & C HONG. (2002) Differential Regulation of Interleukin-6 and Inducible Cyclooxygenase Gene Expression by Cytokines Through Prostaglandin-Dependent and -Independent Mechanisms in Human Dental Pulp Fibroblasts. Journal of Endodontics 28:3, pages 197-201.
Crossref
Ioanna-Maria Karaguni, Karl-Heinz Glüsenkamp, Anette Langerak, Christoph Geisen, Volker Ullrich, Günther Winde, Tarik Möröy & Oliver Müller. (2002) New indene-derivatives with anti-proliferative properties. Bioorganic & Medicinal Chemistry Letters 12:4, pages 709-713.
Crossref
E. C. de Almeida & H. Menezes. (2002) Anti-inflammatory activity of propolis extracts: a review. Journal of Venomous Animals and Toxins 8:2, pages 191-212.
Crossref
Shigefumi Cho, Tie Hong, Guang-Bi Jin, Gen Yoshino, Myota Miura, Yoshihiro Aikawa, Fumiko Yasuno & Jong-Chol Cyong. (2012) The Combination Therapy of Ephedra Herb and Loxoprofen Caused Gastric Lesions in Mice. The American Journal of Chinese Medicine 30:04, pages 571-577.
Crossref
. 2002. Prostacyclin and Its Receptors. Prostacyclin and Its Receptors 1 27 .
Natasha May, Joel Epstein & Barrie Osborne. (2001) Selective COX-2 inhibitors: A review of their therapeutic potential and safety in dentistry. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 92:4, pages 399-405.
Crossref
Fabio Celotti & Stefan Laufer. (2001) Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept. Pharmacological Research 43:5, pages 429-436.
Crossref
Tasia S.W Sam, Shun W Chan, John A Rudd & John H.K Yeung. (2001) Action of glucocorticoids to antagonise cisplatin-induced acute and delayed emesis in the ferret. European Journal of Pharmacology 417:3, pages 231-237.
Crossref
Anita R. Maguire, Stephen J. Plunkett, Sébastien Papot, Martin Clynes, Robert O'Connor & Samantha Touhey. (2001) Synthesis of indomethacin analogues for evaluation as modulators of MRP activity. Bioorganic & Medicinal Chemistry 9:3, pages 745-762.
Crossref
Candice C.N Pillay, Anna K Jäger, Dulcie A Mulholland & J van Staden. (2001) Cyclooxygenase inhibiting and anti-bacterial activities of South African Erythrina species. Journal of Ethnopharmacology 74:3, pages 231-237.
Crossref
Isabel Villegas, Catalina Alarcón de la Lastra, Carmen La Casa, Virginia Motilva & Ma Jose Martı́n. (2001) Effects of food intake and oxidative stress on intestinal lesions caused by meloxicam and piroxicam in rats. European Journal of Pharmacology 414:1, pages 79-86.
Crossref
Márcio L.C. Borsato, Cristiane F.F. Grael, Glória E.P. Souza & Norberto P. Lopes. (2000) Analgesic activity of the lignans from Lychnophora ericoides. Phytochemistry 55:7, pages 809-813.
Crossref
Navtej S. Buttar & Kenneth K. Wang. (2000) The “Aspirin” of the New Millennium: Cyclooxygenase-2 Inhibitors. Mayo Clinic Proceedings 75:10, pages 1027-1038.
Crossref
Christopher T.D Price, Ian R Lee & John E Gustafson. (2000) The effects of salicylate on bacteria. The International Journal of Biochemistry & Cell Biology 32:10, pages 1029-1043.
Crossref
John L. Wallace, Webb McKnight, Brian K. Reuter & Nathalie Vergnolle. (2000) NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 119:3, pages 706-714.
Crossref
Chi-Chuan Tseng & M. Michael Wolfe. (2000) NONSTEROIDAL ANTI-INFLAMMATORY DRUGS. Medical Clinics of North America 84:5, pages 1329-1344.
Crossref
Ryuta Yamazaki, Hiroshi Hatano, Ritsuo Aiyama, Takeshi Matsuzaki, Shusuke Hashimoto & Teruo Yokokura. (2000) Diarylheptanoids suppress expression of leukocyte adhesion molecules on human vascular endothelial cells. European Journal of Pharmacology 404:3, pages 375-385.
Crossref
Gideon Steinbach, Patrick M. Lynch, Robin K.S. Phillips, Marina H. Wallace, Ernest Hawk, Gary B. Gordon, Naoki Wakabayashi, Brian Saunders, Yu Shen, Takashi Fujimura, Li-Kuo Su, Bernard Levin, Louis Godio, Sherri Patterson, Miguel A. Rodriguez-Bigas, Susan L. Jester, Karen L. King, Marta Schumacher, James Abbruzzese, Raymond N. DuBois, Walter N. Hittelman, Stuart Zimmerman, Jeffrey W. Sherman & Gary Kelloff. (2000) The Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor, in Familial Adenomatous Polyposis. New England Journal of Medicine 342:26, pages 1946-1952.
Crossref
Mirna M. Bezerra, Vilma de Lima, Veruska B.M. Alencar, Ivana B. Vieira, Gerly Anne C. Brito, Ronaldo A. Ribeiro & Francisco Airton C. Rocha. (2000) Selective Cyclooxygenase-2 Inhibition Prevents Alveolar Bone Loss in Experimental Periodontitis in Rats. Journal of Periodontology 71:6, pages 1009-1014.
Crossref
M.A Moro, J De Alba, A Cárdenas, J De Cristóbal, J.C Leza, I Lizasoain, M.J.M Dı́az-Guerra, L Boscá & P Lorenzo. (2000) Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices. Neuropharmacology 39:7, pages 1309-1318.
Crossref
KARL‐ERIK ANDERSSON. (2014) TREATMENT OF OVERACTIVE BLADDER: OTHER DRUG MECHANISMS. BJU International 85:S3, pages 51-57.
Crossref
Karl-Erik Andersson. (2000) Treatment of overactive bladder: other drug mechanisms. Urology 55:5, pages 51-57.
Crossref
Yasunori Tsubouchi, Hajime Sano, Ryoji Yamada, Akira Hashiramoto, Masataka Kohno, Yoshiaki Kusaka & Motoharu Kondo. (2000) Preferential inhibition of cyclooxygenase-2 by meloxicam in human rheumatoid synoviocytes. European Journal of Pharmacology 395:3, pages 255-263.
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