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Daniel E. Di Zeo-Sánchez, Antonio Segovia-Zafra, Gonzalo Matilla-Cabello, José M. Pinazo-Bandera, Raúl J. Andrade, M. Isabel Lucena & Marina Villanueva-Paz. (2022) Modeling drug-induced liver injury: current status and future prospects. Expert Opinion on Drug Metabolism & Toxicology 18:9, pages 555-573.
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Richard J. Weaver, Catherine Betts, Eric A.G. Blomme, Helga H.J. Gerets, Klaus Gjervig Jensen, Philip G. Hewitt, Satu Juhila, Gilles Labbe, Michael J. Liguori, Natalie Mesens, Monday O. Ogese, Mikael Persson, Jan Snoeys, James L. Stevens, Tracy Walker & B. Kevin Park. (2017) Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury. Expert Opinion on Drug Metabolism & Toxicology 13:7, pages 767-782.
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M. José Gómez-Lechón, Laia Tolosa & M. Teresa Donato. (2017) Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing. Expert Opinion on Drug Metabolism & Toxicology 13:2, pages 137-148.
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Rachel P. L. van Swelm, Cornelis Kramers, Rosalinde Masereeuw & Frans G. M. Russel. (2014) Application of urine proteomics for biomarker discovery in drug-induced liver injury. Critical Reviews in Toxicology 44:10, pages 823-841.
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Marinka Žitnik & Blaž Zupan. (2014) Matrix factorization-based data fusion for drug-induced liver injury prediction. Systems Biomedicine 2:1, pages 16-22.
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Yong Zhou, Shizhen Qin & Kai Wang. (2013) Biomarkers of drug-induced liver injury. Current Biomarker Findings 3, pages 1-9.
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Richard Warrington. (2012) Drug allergy. Human Vaccines & Immunotherapeutics 8:10, pages 1513-1524.
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Articles from other publishers (48)
Ji Eon Park, Chi-Hoon AhnHyo-Jung LeeDeok Yong SimSu Yeon ParkBonglee KimBum Sang ShimDae Young Lee & Sung-Hoon Kim. (2023) Antioxidant-Based Preventive Effect of Phytochemicals on Anticancer Drug-Induced Hepatotoxicity. Antioxidants & Redox Signaling.
Crossref
Crossref
Ya-Lin Huang, Cristian De Gregorio, Verónica Silva, Álvaro A. Elorza, Patricio Léniz, Víctor Aliaga-Tobar, Vinicius Maracaja-Coutinho, Mauricio Budini, Fernando Ezquer & Marcelo Ezquer. (2023) Administration of Secretome Derived from Human Mesenchymal Stem Cells Induces Hepatoprotective Effects in Models of Idiosyncratic Drug-Induced Liver Injury Caused by Amiodarone or Tamoxifen. Cells 12:4, pages 636.
Crossref
Crossref
Cyriac Abby Philips, Arif Hussain Theruvath & Resmi Ravindran. (2022) Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Reports 15:3, pages e247867.
Crossref
Crossref
Jack Uetrecht, Denis M. Grant & Peter G. Wells. 2022. Atkinson's Principles of Clinical Pharmacology. Atkinson's Principles of Clinical Pharmacology
267
302
.
Antonio Segovia-Zafra, Daniel E. Di Zeo-Sánchez, Carlos López-Gómez, Zeus Pérez-Valdés, Eduardo García-Fuentes, Raúl J. Andrade, M. Isabel Lucena & Marina Villanueva-Paz. (2021) Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction. Acta Pharmaceutica Sinica B 11:12, pages 3685-3726.
Crossref
Crossref
K. A. Pazinenko , N. N. Chuchkova, M. V. Smetanina, O. A. Pazinenko, K. E. Panteleev, G. V. Ivanov & N. V. Kormilina. (2021) Dynamics of Biochemical and Cytological Parameters of Rat Blood in Simulated Chronic Alimentary Methionine-Induced Homocysteinemia. Journal Biomed 17:2, pages 46-57.
Crossref
Crossref
Florian Padberg, Tessa Höper, Sebastian Henkel, Dominik Driesch, Andreas Luch & Sebastian Zellmer. (2021) Novel indirect co-culture of immortalised hepatocytes with monocyte derived macrophages is characterised by pro-inflammatory cytokine networks. Toxicology in Vitro 73, pages 105134.
Crossref
Crossref
Steve U. Ayobahan, Sebastian Eilebrecht, Lisa Baumann, Matthias Teigeler, Henner Hollert, Stefan Kalkhof, Elke Eilebrecht & Christoph Schäfers. (2020) Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Chemosphere 240, pages 124970.
Crossref
Crossref
Xiaolin Wang & Xiangmei Chen. (2020) Clinical Characteristics of 162 Patients with Drug-Induced Liver and/or Kidney Injury. BioMed Research International 2020, pages 1-11.
Crossref
Crossref
Zhilei Wang, Guang Xu, Xiaoyan Zhan, Youping Liu, Yuan Gao, Nian Chen, Yuming Guo, Ruisheng Li, Tingting He, Xueai Song, Ming Niu, Jiabo Wang, Zhaofang Bai & Xiaohe Xiao. (2019) Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice. Archives of Toxicology 93:12, pages 3585-3599.
Crossref
Crossref
Ben L. Da, Gil Ben-Yakov, David Kleiner & Christopher Koh. (2018) Drug-Induced Liver Injury: Understanding the Different Immune-Mediated Phenotypes and Clinical Management. Current Hepatology Reports 17:3, pages 235-244.
Crossref
Crossref
Hui Ye, Leonard J Nelson, Manuel Gómez del Moral, Eduardo Martínez-Naves & Francisco Javier Cubero. (2018) Dissecting the molecular pathophysiology of drug-induced liver injury. World Journal of Gastroenterology 24:13, pages 1373-1385.
Crossref
Crossref
Michele Visentin, Daniela Lenggenhager, Zhibo Gai & Gerd A. Kullak-Ublick. (2018) Drug-induced bile duct injury. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1864:4, pages 1498-1506.
Crossref
Crossref
Annie Borgne-Sanchez & Bernard Fromenty. 2018. Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants. Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
47
72
.
Meir Mizrahi, Tomer Adar, Gadi Lalazar, Dean Nachman, Madi El Haj, Ami Ben Ya’acov, Yoav Lichtenstein, Yehudit Shabat, Dimitri Kanovich, Lida Zolotarov & Yaron Ilan. (2018) Glycosphingolipids Prevent APAP and HMG-CoA Reductase Inhibitors-mediated Liver Damage: A Novel Method for “Safer Drug” Formulation that Prevents Drug-induced Liver Injury. Journal of Clinical and Translational Hepatology 6:2, pages 1-8.
Crossref
Crossref
Harshad Devarbhavi, Herbert L. Bonkovsky, Mark Russo & Naga Chalasani. 2018. Zakim and Boyer's Hepatology. Zakim and Boyer's Hepatology
844
890.e17
.
C Ju, E Phillips, M.P. Holt, Y.R. Gao & C. Lammert. 2018. Comprehensive Toxicology. Comprehensive Toxicology
346
367
.
E.L. LeCluyse, L.M. Norona, J.A. Akingbasote, L.S. Howell, J.L. Woodhead, M.J. Cross, A.B. Roth & C.E. Goldring. 2018. Comprehensive Toxicology. Comprehensive Toxicology
651
712
.
J. Gerry Kenna, John C. Waterton, Andreas Baudy, Aleksandra Galetin, Catherine D. G. Hines, Paul Hockings, Manishkumar Patel, Daniel Scotcher, Steven Sourbron, Sabina Ziemian & Gunnar Schuetz. 2018. Drug-Induced Liver Toxicity. Drug-Induced Liver Toxicity
627
651
.
Pius Joseph. (2017) Transcriptomics in toxicology. Food and Chemical Toxicology 109, pages 650-662.
Crossref
Crossref
Adriaan D. Bastiaan Vliegenthart, Chunmin Wei, Charlotte Buckley, Cécile Berends, Carmelita M. J. de Potter, Sarah Schneemann, Jorge Del PozoCarl Tucker, John J. Mullins, David J. Webb & James W. Dear. (2017) Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model. Toxicological Sciences 159:2, pages 380-391.
Crossref
Crossref
Zhenlin Huang, Minwei Chen, Jiaqi Zhang, Yuchen Sheng & Lili Ji. (2017) Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice. Toxicology and Applied Pharmacology 333, pages 35-42.
Crossref
Crossref
Yue-cheng Yu, Yi-min Mao, Cheng-wei Chen, Jin-jun Chen, Jun Chen, Wen-ming Cong, Yang Ding, Zhong-ping Duan, Qing-chun Fu, Xiao-yan Guo, Peng Hu, Xi-qi Hu, Ji-dong Jia, Rong-tao Lai, Dong-liang Li, Ying-xia Liu, Lun-gen Lu, Shi-wu Ma, Xiong Ma, Yue-min Nan, Hong Ren, Tao Shen, Hao Wang, Ji-yao Wang, Tai-ling Wang, Xiao-jin Wang, Lai Wei, Qing Xie, Wen Xie, Chang-qing Yang, Dong-liang Yang, Yan-yan Yu, Min-de Zeng, Li Zhang, Xin-yan Zhao & Hui Zhuang. (2017) CSH guidelines for the diagnosis and treatment of drug-induced liver injury. Hepatology International 11:3, pages 221-241.
Crossref
Crossref
Toru Usui & Dean J. Naisbitt. (2017) Human leukocyte antigen and idiosyncratic adverse drug reactions. Drug Metabolism and Pharmacokinetics 32:1, pages 21-30.
Crossref
Crossref
Alexander D. Roth & Moo-Yeal Lee. (2017) Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays. BioMed Research International 2017, pages 1-23.
Crossref
Crossref
Cezary Chojnacki, Aleksandra Błońska & Jan Chojnacki. (2017) The Effects of Melatonin on Elevated Liver Enzymes during Statin Treatment. BioMed Research International 2017, pages 1-7.
Crossref
Crossref
Danielle L. Brown. 2017. Immunopathology in Toxicology and Drug Development. Immunopathology in Toxicology and Drug Development
329
417
.
Philip Moore & Keith Burkhart. 2017. Critical Care Toxicology. Critical Care Toxicology
693
739
.
Jiekun Xuan, Si Chen, Baitang Ning, William H. Tolleson & Lei Guo. (2016) Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity. Chemico-Biological Interactions 255, pages 63-73.
Crossref
Crossref
Natalie S. Holman, Merrie Mosedale, Kristina K. Wolf, Edward L. LeCluyse & Paul B. Watkins. (2016) Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?. Toxicological Sciences 151:2, pages 365-375.
Crossref
Crossref
J. Gerry Kenna, Mikael Persson, Scott Q. Siler, Ke Yu, Chuchu Hu, Minjun Chen, Joshua Xu, Weida Tong, Yvonne Will & Michael D. Aleo. 2016. Drug Discovery Toxicology. Drug Discovery Toxicology
93
129
.
RD Fannin, K Gerrish, SO Sieber, PR Bushel, PB Watkins & RS Paules. (2016) Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophen. Clinical Pharmacology & Therapeutics 99:4, pages 432-441.
Crossref
Crossref
Philip Moore & Keith Burkhart. 2016. Critical Care Toxicology. Critical Care Toxicology
1
47
.
A Tailor, L Faulkner, DJ Naisbitt & BK Park. (2015) The chemical, genetic and immunological basis of idiosyncratic drug–induced liver injury. Human & Experimental Toxicology 34:12, pages 1310-1317.
Crossref
Crossref
Binxia Chang, Ming‐Jiang Xu, Zhou Zhou, Yan Cai, Man Li, Wei Wang, Dechun Feng, Adeline Bertola, Hua Wang, George Kunos & Bin Gao. (2015) Short‐ or long‐term high‐fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: An important role for CXCL1. Hepatology 62:4, pages 1070-1085.
Crossref
Crossref
Ryan Nattrass, Lee Faulkner, Marc Vocanson, Daniel J. Antoine, Anja Kipar, Gerry Kenna, Jean-Francois Nicolas, B. Kevin Park & Dean J. Naisbitt. (2015) Activation of Flucloxacillin-Specific CD8+ T-Cells With the Potential to Promote Hepatocyte Cytotoxicity in a Mouse Model. Toxicological Sciences 146:1, pages 146-156.
Crossref
Crossref
Nina Senutovitch, Lawrence Vernetti, Robert Boltz, Richard DeBiasio, Albert Gough & D Lansing Taylor. (2015) Fluorescent protein biosensors applied to microphysiological systems. Experimental Biology and Medicine 240:6, pages 795-808.
Crossref
Crossref
François Ballet. (2015) Preventing Drug-Induced Liver Injury: How Useful Are Animal Models?. Digestive Diseases 33:4, pages 477-485.
Crossref
Crossref
A. D. Bastiaan Vliegenthart, Carl S. Tucker, Jorge Del Pozo & James W. Dear. (2014) Zebrafish as model organisms for studying drug-induced liver injury. British Journal of Clinical Pharmacology 78:6, pages 1217-1227.
Crossref
Crossref
Yonas Getachew, Frank A. Cusimano, Laura P. James & Dwain L. Thiele. (2014) The role of intrahepatic CD3+/CD4−/CD8− double negative T (DN T) cells in enhanced acetaminophen toxicity. Toxicology and Applied Pharmacology 280:2, pages 264-271.
Crossref
Crossref
David E Amacher. (2013) Female gender as a susceptibility factor for drug-induced liver injury. Human & Experimental Toxicology 33:9, pages 928-939.
Crossref
Crossref
Jürgen Borlak, Anil Chougule & Prafull Kumar Singh. (2014) How useful are clinical liver function tests in in vitro human hepatotoxicity assays?. Toxicology in Vitro 28:5, pages 784-795.
Crossref
Crossref
Yuchen Sheng, Yibo Ma, Zhongping Deng, Zhengtao Wang & Lili Ji. (2014) Cytokines as potential biomarkers of liver toxicity induced by Dioscorea bulbifera L.. BioScience Trends 8:1, pages 32-37.
Crossref
Crossref
Jens Schümann & Michael Kammüller. 2005. Encyclopedia of Immunotoxicology. Encyclopedia of Immunotoxicology
1
6
.
Lisl K. M. Shoda, Jeffrey L. Woodhead, Scott Q. Siler, Paul B. Watkins & Brett A. Howell. (2014)
Linking physiology to toxicity using DILIsym
®
, a mechanistic mathematical model of drug-induced liver injury
. Biopharmaceutics & Drug Disposition 35:1, pages 33-49.
Crossref
Crossref
Patricio Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes Georg Bode, Jennifer Bolleyn, Christoph Borner, Jan Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, María Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Chris E. P. Goldring, María José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann-Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens M. Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak-Ublick, Edward L. LeCluyse, Peng Lu, Jennifer Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz-Soja, Patrick McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nussler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan A. Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiss, Agata Widera, Courtney G. Woods, Jinghai James Xu, Kathy M. Yarborough & Jan G. Hengstler. (2013) Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Archives of Toxicology 87:8, pages 1315-1530.
Crossref
Crossref
Rashmi R. Shah, Joel Morganroth & Devron R. Shah. (2013) Hepatotoxicity of Tyrosine Kinase Inhibitors: Clinical and Regulatory Perspectives. Drug Safety 36:7, pages 491-503.
Crossref
Crossref
C. David Williams & Hartmut Jaeschke. (2012) Role of innate and adaptive immunity during drug-induced liver injury. Toxicology Research 1:3, pages 161.
Crossref
Crossref