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Original Article

Ondansetron-loaded chitosan microspheres for nasal antiemetic drug delivery: an alternative approach to oral and parenteral routes

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Pages 806-813 | Received 10 Jul 2009, Accepted 29 Nov 2009, Published online: 06 Feb 2010

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Read on this site (10)

Jing Zhou, Yuanyuan Chen, Mengmeng Luo, Fen Deng, Sen Lin, Wencan Wu, Guqiang Li & Kaihui Nan. (2019) Dual cross-linked chitosan microspheres formulated with spray-drying technique for the sustained release of levofloxacin. Drug Development and Industrial Pharmacy 45:4, pages 568-576.
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Ting-Ting Yang, Bao-Fang Wen, Kang Liu, Meng Qin, Yuan-Yuan Gao, De-Jun Ding, Wen-Tong Li, Yun-Xiang Zhang & Wei-Fen Zhang. (2018) Cyclosporine A/porous quaternized chitosan microspheres as a novel pulmonary drug delivery system. Artificial Cells, Nanomedicine, and Biotechnology 46:sup2, pages 552-564.
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Amrish Kumar, Aditya Nath Pandey & Sunil Kumar Jain. (2016) Nasal-nanotechnology: revolution for efficient therapeutics delivery. Drug Delivery 23:3, pages 671-683.
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Vipul D Prajapati, Girish K Jani & Jinita R Kapadia. (2015) Current knowledge on biodegradable microspheres in drug delivery. Expert Opinion on Drug Delivery 12:8, pages 1283-1299.
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M Christofaki & A Papaioannou. (2014) Ondansetron: a review of pharmacokinetics and clinical experience in postoperative nausea and vomiting. Expert Opinion on Drug Metabolism & Toxicology 10:3, pages 437-444.
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Ali Demir Sezer & Erdal Cevher. (2012) Topical drug delivery using chitosan nano- and microparticles. Expert Opinion on Drug Delivery 9:9, pages 1129-1146.
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Yildiz Ozsoy & Sevgi Güngör. (2011) Nasal route: an alternative approach for antiemetic drug delivery. Expert Opinion on Drug Delivery 8:11, pages 1439-1453.
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Yue-Hua Liu, Xi Zhu, Dan Zhou, Yun Jin, Chun-Yan Zhao, Zhi-Rong Zhang & Yuan Huang. (2011) pH-Sensitive and mucoadhesive microspheres for duodenum-specific drug delivery system. Drug Development and Industrial Pharmacy 37:7, pages 868-874.
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Emmamuel O. Akala, Pornruedee Wiriyacoonkasem & Gaofeng Pan. (2011) Studies on in vitro availability, degradation, and thermal properties of naltrexone-loaded biodegradable microspheres. Drug Development and Industrial Pharmacy 37:6, pages 673-684.
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Articles from other publishers (19)

Paolina Lukova & Plamen Katsarov. (2023) Contemporary Aspects of Designing Marine Polysaccharide Microparticles as Drug Carriers for Biomedical Application. Pharmaceutics 15:8, pages 2126.
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Ljiljana Djekic. 2023. Nasal Drug Delivery. Nasal Drug Delivery 189 234 .
Zeliha Duygu Özdal, Yakup Gültekin, İmran Vural & Sevgi Takka. (2022) Development and characterization of polymeric nanoparticles containing ondansetron hydrochloride as a hydrophilic drug. Journal of Drug Delivery Science and Technology 74, pages 103599.
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Vivek P. Chavda, Gargi Jogi, Nirav Shah, Mansi N. Athalye, Nirav Bamaniya, Lalitkumar K Vora & Ana Cláudia Paiva-Santos. (2022) Advanced particulate carrier-mediated technologies for nasal drug delivery. Journal of Drug Delivery Science and Technology 74, pages 103569.
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Patrícia Henriques, Ana Fortuna & Slavomíra Doktorovová. (2022) Spray dried powders for nasal delivery: Process and formulation considerations. European Journal of Pharmaceutics and Biopharmaceutics 176, pages 1-20.
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Paola Mura, Francesca Maestrelli, Marzia Cirri & Natascia Mennini. (2022) Multiple Roles of Chitosan in Mucosal Drug Delivery: An Updated Review. Marine Drugs 20:5, pages 335.
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Barbara R. Conway & Muhammad U. Ghori. 2021. Fundamentals of Drug Delivery. Fundamentals of Drug Delivery 393 432 .
Nozad Rashid Hussein, Huner Kamal Omer, Abdelbary M.A. Elhissi & Waqar Ahmed. 2020. Advances in Medical and Surgical Engineering. Advances in Medical and Surgical Engineering 279 311 .
Plamen Katsarov, Bissera Pilicheva, Yordanka Uzunova, Georgi Gergov & Margarita Kassarova. (2018) Chemical cross-linking: A feasible approach to prolong doxylamine/pyridoxine release from spray-dried chitosan microspheres. European Journal of Pharmaceutical Sciences 123, pages 387-394.
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Francisca Araújo, José das Neves, João Pedro Martins, Pedro L. Granja, Hélder A. Santos & Bruno Sarmento. (2017) Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals. Progress in Materials Science 89, pages 306-344.
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A. Raquel Madureira, Bruno Sarmento & Manuela Pintado. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 275 297 .
Priti Girotra & Shailendra Kumar Singh. 2015. Handbook of Polymers for Pharmaceutical Technologies. Handbook of Polymers for Pharmaceutical Technologies 33 60 .
Luca Casettari & Lisbeth Illum. (2014) Chitosan in nasal delivery systems for therapeutic drugs. Journal of Controlled Release 190, pages 189-200.
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Ana Fortuna, Gilberto Alves, Ana Serralheiro, Joana Sousa & Amílcar Falcão. (2014) Intranasal delivery of systemic-acting drugs: Small-molecules and biomacromolecules. European Journal of Pharmaceutics and Biopharmaceutics 88:1, pages 8-27.
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Mamdouh. Abdel Mouez, Noha M. Zaki, Samar Mansour & Ahmed S. Geneidi. (2014) Bioavailability enhancement of verapamil HCl via intranasal chitosan microspheres. European Journal of Pharmaceutical Sciences 51, pages 59-66.
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Ling Chong Wang, Liu Qing Di, Rui Liu & Hao Wu. (2013) Characterizations and microsphere formulation of polysaccharide from the marine clam (Mactra veneriformis). Carbohydrate Polymers 92:1, pages 106-113.
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Ana Serralheiro, Gilberto Alves, Joana Sousa, Ana Fortuna & Amílcar Falcão. 2013. Nasal Physiology and Pathophysiology of Nasal Disorders. Nasal Physiology and Pathophysiology of Nasal Disorders 191 215 .
Ana Serralheiro, Gilberto Alves & Amílcar Falcão. (2012) Bioanalysis of small-molecule drugs in nasal and paranasal tissues and secretions: Current status and perspectives. Open Chemistry 10:3, pages 686-702.
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Elizabeth Rosado Balmayor, Helena Sepulveda Azevedo & Rui L. Reis. (2011) Controlled Delivery Systems: From Pharmaceuticals to Cells and Genes. Pharmaceutical Research 28:6, pages 1241-1258.
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