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Original Article

Successful Carboxypeptidase G2 Rescue in Delayed Methotrexate Elimination Due to Renal Failure

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Pages 471-477 | Received 23 Jan 1995, Accepted 20 Mar 1995, Published online: 09 Jul 2009

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Parvin F Peddi, Srinivas Peddi, Edgardo S Santos & Daniel Morgensztern. (2014) Central nervous system toxicities of chemotherapeutic agents. Expert Review of Anticancer Therapy 14:7, pages 857-863.
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Jacalyn M Green. (2012) Glucarpidase to combat toxic levels of methotrexate in patients. Therapeutics and Clinical Risk Management 8, pages 403-413.
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Daniel M Patterson & Siow Ming Lee. (2010) Glucarpidase following high-dose methotrexate: update on development. Expert Opinion on Biological Therapy 10:1, pages 105-111.
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Martina Hum & Barton A. Kamen. (1995) Successful Carboxypeptidase G2 Rescue in Delayed MTX-Elimination Due to Renal Failure. Pediatric Hematology and Oncology 12:6, pages 521-524.
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Articles from other publishers (18)

Zachary L. Taylor, Tomoyuki Mizuno, Nieko C. Punt, Balaji Baskaran, Adriana Navarro Sainz, William Shuman, Nicholas Felicelli, Alexander A. Vinks, Jesper Heldrup & Laura B. Ramsey. (2020) MTXPK.org: A Clinical Decision Support Tool Evaluating High‐Dose Methotrexate Pharmacokinetics to Inform Post‐Infusion Care and Use of Glucarpidase. Clinical Pharmacology & Therapeutics 108:3, pages 635-643.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 115 129 .
Jeffrey R. Scott, Yinmei Zhou, Cheng Cheng, Deborah A. Ward, Hope D. Swanson, Alejandro R. Molinelli, Clinton F. Stewart, Fariba Navid, Sima Jeha, Mary V. Relling & Kristine R. Crews. (2015) Comparable efficacy with varying dosages of glucarpidase in pediatric oncology patients. Pediatric Blood & Cancer 62:9, pages 1518-1522.
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Anthony M. Christensen, Jennifer L. Pauley, Alejandro R. Molinelli, John C. Panetta, Deborah A. Ward, Clinton F. Stewart, James M. Hoffman, Scott C. Howard, Ching‐Hon Pui, Alberto S. Pappo, Mary V. Relling & Kristine R. Crews. (2012) Resumption of high‐dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients. Cancer 118:17, pages 4321-4330.
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Avinash Gupta & Mark Middleton. 2011. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 935 962 .
Brigitte C. WidemannFrank M. BalisAeRang KimMatthew BoronNalini JayaprakashAiman ShalabiMichelle O'BrienMichelle EbyDiane E. ColeRobert F. MurphyElizabeth FoxPercy IvyPeter C. Adamson. (2010) Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome. Journal of Clinical Oncology 28:25, pages 3979-3986.
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Silas W. Smith. 2010. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 397 460 .
Hélène Blasco, Stéphanie Silly, Jean-François Tournamille, Emmanuel Gyan, Delphine Sénécal, Virginie André, Philippe Colombat & Chantal Le Guellec. (2008) Les critères d’utilisation de la carboxypeptidase dans les surexpositions au méthotrexate doivent être mieux définis. Therapies 63:1, pages 19-28.
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Ronald L. Snyder. (2007) Resumption of high-dose methotrexate after methotrexate-induced nephrotoxicity and carboxypeptidase G2 use. American Journal of Health-System Pharmacy 64:11, pages 1163-1169.
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S. Bielack, D. Carrle & K. Winkler. 2007. Therapiekonzepte Onkologie. Therapiekonzepte Onkologie 918 935 .
S Buchen, D Ngampolo, R G Melton, C Hasan, A Zoubek, G Henze, U Bode & G Fleischhack. (2005) Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure. British Journal of Cancer 92:3, pages 480-487.
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Brigitte C. Widemann, Frank M. Balis, Beate Kempf‐Bielack, Stefan Bielack, Charles B. Pratt, Stefano Ferrari, Gaetano Bacci, Alan W. Craft & Peter C. Adamson. (2004) High‐dose methotrexate‐induced nephrotoxicity in patients with osteosarcoma. Cancer 100:10, pages 2222-2232.
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Hélène Peyriere, Marylène Cociglio, Geneviève Margueritte, Catherine Vallat, Jean-Pierre Blayac & Dominique Hillaire-Buys. (2004) Optimal Management of Methotrexate Intoxication in a Child with Osteosarcoma. Annals of Pharmacotherapy 38:3, pages 422-427.
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Elpis Mantadakis, Zora R. Rogers, Angela K. Smith, Raymond Quigley, Arleen F. Ratliff & Barton A. Kamen. (1999) Delayed Methotrexate Clearance in a Patient With Sickle Cell Anemia and Osteosarcoma. Journal of Pediatric Hematology/Oncology 21:2, pages 165-169.
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K. Winkler & S. Bielack. 1998. Therapiekonzepte Onkologie. Therapiekonzepte Onkologie 830 854 .
Jan L. Hillson & Daniel E. Furst. (1997) PHARMACOLOGY AND PHARMACOKINETICS OF METHOTREXATE IN RHEUMATIC DISEASE. Rheumatic Disease Clinics of North America 23:4, pages 757-778.
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&NA;. (1997) Intrathecal Leukovorin after Intrathecal Methotrexate Overdose. Journal of Pediatric Hematology/Oncology 19:3, pages 268-269.
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Martina C. Hum & Barton A. Kamen. (1996) Folate, antifolates, and folate analogs in Pediatric Oncology. Investigational New Drugs 14:1, pages 101-111.
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