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Original Article

Autoantibodies in Primary Sjögren's Syndrome: New Insights into Mechanisms of Autoantibody Diversification and Disease Pathogenesis

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Pages 123-132 | Received 14 Sep 2000, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Lara A. Aqrawi, Janicke Liaaen Jensen, Siren Fromreide, Hilde Kanli Galtung & Kathrine Skarstein. (2020) Expression of NGAL-specific cells and mRNA levels correlate with inflammation in the salivary gland, and its overexpression in the saliva, of patients with primary Sjögren’s syndrome. Autoimmunity 53:6, pages 333-343.
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Kathrine Skarstein, Janicke Liaaen Jensen, Hilde Galtung, Roland Jonsson, Karl Brokstad & Lara A. Aqrawi. (2019) Autoantigen-specific B cells and plasma cells are prominent in areas of fatty infiltration in salivary glands of patients with primary Sjögren’s syndrome. Autoimmunity 52:7-8, pages 242-250.
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Kathrine Skarstein, Lara A. Aqrawi, Gunnvor Øijordsbakken, Roland Jonsson & Janicke Liaaen Jensen. (2016) Adipose tissue is prominent in salivary glands of Sjögren’s syndrome patients and appears to influence the microenvironment in these organs. Autoimmunity 49:5, pages 338-346.
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Amy Donate, Alexandria Voigt & Cuong Q Nguyen. (2014) The value of animal models to study immunopathology of primary human Sjögren's syndrome symptoms. Expert Review of Clinical Immunology 10:4, pages 469-481.
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Lara A. Aqrawi, Karl A. Brokstad, Kjerstin Jakobsen, Roland Jonsson & Kathrine Skarstein. (2012) Low number of memory B cells in the salivary glands of patients with primary Sjögren's syndrome. Autoimmunity 45:7, pages 547-555.
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Miguel Cordero-Coma, Fahd Anzaar, Lucia Sobrin & C. Stephen Foster. (2007) Systemic Immunomodulatory Therapy in Severe Dry Eye Secondary to Inflammation. Ocular Immunology and Inflammation 15:2, pages 99-104.
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Chris T Derk. (2005) Sjogren’s syndrome: models of pathogenesis and treatment targets. Expert Opinion on Therapeutic Patents 15:11, pages 1587-1594.
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Clara Chivasso, Claudia D’Agostino, Dorian Parisis, Muhammad S. Soyfoo & Christine Delporte. (2023) Involvement of aquaporin 5 in Sjögren’s syndrome. Autoimmunity Reviews 22:3, pages 103268.
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Harim T. dos Santos, Kihoon Nam, Diana Gil, Venkata Yellepeddi & Olga J. Baker. (2023) Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome. Frontiers in Immunology 13.
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Cordula DahlmannCordula Dahlmann. 2019. Sicca-Syndrom. Sicca-Syndrom 1 17 .
Alexandria Voigt, Katherine Bohn, Sukesh Sukumaran, Carol M. Stewart, Indraneel Bhattacharya & Cuong Q. Nguyen. (2018) Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis. Clinical Immunology 192, pages 58-67.
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Ching-Shuen Wang & Olga J. Baker. (2018) The G-Protein–Coupled Receptor ALX/Fpr2 Regulates Adaptive Immune Responses in Mouse Submandibular Glands. The American Journal of Pathology 188:7, pages 1555-1562.
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Arun Wanchoo, Alexandria Voigt, Sukesh Sukumaran, Carol M. Stewart, Indraneel Bhattacharya & Cuong Q. Nguyen. (2017) Single-cell analysis reveals sexually dimorphic repertoires of Interferon-γ and IL-17A producing T cells in salivary glands of Sjögren’s syndrome mice. Scientific Reports 7:1.
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L A Aqrawi, M Kvarnström, K A Brokstad, R Jonsson, K Skarstein & M Wahren-Herlenius. (2014) Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjögren's syndrome. Clinical and Experimental Immunology 177:1, pages 244-252.
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Cuong Q. Nguyen, Adebola O. Ogunniyi, Afife Karabiyik & J. Christopher Love. (2013) Single-Cell Analysis Reveals Isotype-Specific Autoreactive B Cell Repertoires in Sjögren’s Syndrome. PLoS ONE 8:3, pages e58127.
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Toshiharu Hayashi. (2011) Dysfunction of Lacrimal and Salivary Glands in Sjögren's Syndrome: Nonimmunologic Injury in Preinflammatory Phase and Mouse Model. Journal of Biomedicine and Biotechnology 2011, pages 1-15.
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