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Jens Wölfelschneider, Thomas Friedrich, Robert Lüchtenborg, Klemens Zink, Michael Scholz, Lei Dong, Marco Durante & Christoph Bert. (2016) Impact of fractionation and number of fields on dose homogeneity for intra-fractionally moving lung tumors using scanned carbon ion treatment. Radiotherapy and Oncology 118:3, pages 498-503.
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Nicole B. Averbeck, Jana Topsch, Michael Scholz, Wilma Kraft-Weyrather, Marco Durante & Gisela Taucher-Scholz. (2016) Efficient Rejoining of DNA Double-Strand Breaks despite Increased Cell-Killing Effectiveness following Spread-Out Bragg Peak Carbon-Ion Irradiation. Frontiers in Oncology 6.
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Kathryn D. Held, Hidemasa Kawamura, Takuya Kaminuma, Athena Evalour S. Paz, Yukari Yoshida, Qi Liu, Henning Willers & Akihisa Takahashi. (2016) Effects of Charged Particles on Human Tumor Cells. Frontiers in Oncology 6.
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G Russo, A Attili, G Battistoni, D Bertrand, F Bourhaleb, F Cappucci, M Ciocca, A Mairani, F M Milian, S Molinelli, M C Morone, S Muraro, T Orts, V Patera, P Sala, E Schmitt, G Vivaldo & F Marchetto. (2016) A novel algorithm for the calculation of physical and biological irradiation quantities in scanned ion beam therapy: the beamlet superposition approach. Physics in Medicine and Biology 61:1, pages 183-214.
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Naruhiro Matsufuji. 2016. Particle Radiotherapy. Particle Radiotherapy
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Francesco Tommasino, Emanuele Scifoni & Marco Durante. (2015) New Ions for Therapy. International Journal of Particle Therapy 2:3, pages 428-438.
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Robert D Stewart, Seth W Streitmatter, David C Argento, Charles Kirkby, John T Goorley, Greg Moffitt, Tatjana Jevremovic & George A Sandison. (2015) Rapid MCNP simulation of DNA double strand break (DSB) relative biological effectiveness (RBE) for photons, neutrons, and light ions. Physics in Medicine and Biology 60:21, pages 8249-8274.
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Lisa Herr, Thomas Friedrich, Marco Durante & Michael Scholz. (2015) A Comparison of Kinetic Photon Cell Survival Models. Radiation Research 184:5, pages 494-508.
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T.E. Schmid, W. Friedland, C. Greubel, S. Girst, J. Reindl, C. Siebenwirth, K. Ilicic, E. Schmid, G. Multhoff, E. Schmitt, P. Kundrát & G. Dollinger. (2015) Sub-micrometer 20 MeV protons or 45 MeV lithium spot irradiation enhances yields of dicentric chromosomes due to clustering of DNA double-strand breaks. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 793, pages 30-40.
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Florian Kamp, Gonzalo Cabal, Andrea Mairani, Katia Parodi, Jan J. Wilkens & David J. Carlson. (2015) Fast Biological Modeling for Voxel-based Heavy Ion Treatment Planning Using the Mechanistic Repair-Misrepair-Fixation Model and Nuclear Fragment Spectra. International Journal of Radiation Oncology*Biology*Physics 93:3, pages 557-568.
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Johanna MirschFrancesco TommasinoAntonia FrohnsSandro ConradMarco Durante, Michael ScholzThomas FriedrichMarkus Löbrich. (2015) Direct measurement of the 3-dimensional DNA lesion distribution induced by energetic charged particles in a mouse model tissue. Proceedings of the National Academy of Sciences 112:40, pages 12396-12401.
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O Steinsträter, U Scholz, T Friedrich, M Krämer, R Grün, M Durante & M Scholz. (2015) Integration of a model-independent interface for RBE predictions in a treatment planning system for active particle beam scanning. Physics in Medicine and Biology 60:17, pages 6811-6831.
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F. Tommasino, T. Friedrich, U. Scholz, G. Taucher-Scholz, M. Durante & M. Scholz. (2015) Application of the local effect model to predict DNA double-strand break rejoining after photon and high-LET irradiation. Radiation Protection Dosimetry 166:1-4, pages 66-70.
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T. Friedrich, M. Durante & M. Scholz. (2015) Simulation of DSB yield for high LET radiation. Radiation Protection Dosimetry 166:1-4, pages 61-65.
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W. Friedland, P. Kundrát & E. Schmitt. (2015) Modelling proton bunches focussed to submicrometre scales: low-LET radiation damage in high-LET-like spatial structure. Radiation Protection Dosimetry 166:1-4, pages 34-37.
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Lisa Herr, Igor Shuryak, Thomas Friedrich, Michael Scholz, Marco Durante & David J. Brenner. (2015) New Insight into Quantitative Modeling of DNA Double-Strand Break Rejoining. Radiation Research 184:3, pages 280.
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Y W Huang, C Y Pan, Y Y Hsiao, T C Chao, C C Lee & C J Tung. (2015)
Monte Carlo simulations of the relative biological effectiveness for DNA double strand breaks from 300 MeV u
−1
carbon-ion beams
. Physics in Medicine and Biology 60:15, pages 5995-6012.
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Benjamin J. Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura & Yoshiya Shimada. (2015) Genetic Analysis of T Cell Lymphomas in Carbon Ion-Irradiated Mice Reveals Frequent Interstitial Chromosome Deletions: Implications for Second Cancer Induction in Normal Tissues during Carbon Ion Radiotherapy. PLOS ONE 10:6, pages e0130666.
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Francesco Tommasino, Thomas Friedrich, Burkhard Jakob, Barbara Meyer, Marco Durante & Michael Scholz. (2015) Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study. PLOS ONE 10:6, pages e0129416.
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Emanuele Scifoni. (2015) Radiation biophysical aspects of charged particles: From the nanoscale to therapy. Modern Physics Letters A 30:17, pages 1540019.
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Antonia Hufnagl, Lisa Herr, Thomas Friedrich, Marco Durante, Gisela Taucher-Scholz & Michael Scholz. (2015) The link between cell-cycle dependent radiosensitivity and repair pathways: A model based on the local, sister-chromatid conformation dependent switch between NHEJ and HR. DNA Repair 27, pages 28-39.
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Rebecca Grün, Thomas Friedrich, Michael Krämer, Klemens Zink, Marco Durante, Rita Engenhart-Cabillic & Michael Scholz. (2015) Assessment of potential advantages of relevant ions for particle therapy: A model based study. Medical Physics 42:2, pages 1037-1047.
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A Cometto, G Russo, F Bourhaleb, F M Milian, S Giordanengo, F Marchetto, R Cirio & A Attili. (2014) Direct evaluation of radiobiological parameters from clinical data in the case of ion beam therapy: an alternative approach to the relative biological effectiveness. Physics in Medicine and Biology 59:23, pages 7393-7417.
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Daniel Habermehl, Katarina Ilicic, Sarah Dehne, Stefan Rieken, Lena Orschiedt, Stephan Brons, Thomas Haberer, Klaus-Josef Weber, Jürgen Debus & Stephanie E. Combs. (2014) The Relative Biological Effectiveness for Carbon and Oxygen Ion Beams Using the Raster-Scanning Technique in Hepatocellular Carcinoma Cell Lines. PLoS ONE 9:12, pages e113591.
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Matthias Uhl, Lutz Edler, Alexandra D Jensen, Gregor Habl, Jan Oelmann, Falk Röder, Oliver Jäckel, Jürgen Debus & Klaus Herfarth. (2014) Randomized phase II trial of hypofractionated proton versus carbon ion radiation therapy in patients with sacrococcygeal chordoma-the ISAC trial protocol. Radiation Oncology 9:1.
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Eugene Surdutovich & Andrey V. Solov’yov. (2014) Multiscale approach to the physics of radiation damage with ions. The European Physical Journal D 68:11.
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Fernanda Villegas, Nina Tilly, Gloria Bäckström & Anders Ahnesjö. (2014)
Cluster pattern analysis of energy deposition sites for the brachytherapy sources
103
Pd,
125
I,
192
Ir,
137
Cs, and
60
Co
. Physics in Medicine and Biology 59:18, pages 5531-5543.
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He Wang & Oleg N Vassiliev. (2014) Radial dose distributions from protons of therapeutic energies calculated with Geant4-DNA. Physics in Medicine and Biology 59:14, pages 3657-3668.
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Thomas Friedrich, Uwe Scholz, Marco Durante & Michael Scholz. (2014) RBE of ion beams in hypofractionated radiotherapy (SBRT). Physica Medica 30:5, pages 588-591.
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F. Kamp, S. Brüningk, G. Cabal, A. Mairani, K. Parodi & J.J. Wilkens. (2014) Variance-based sensitivity analysis of biological uncertainties in carbon ion therapy. Physica Medica 30:5, pages 583-587.
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Thomas Friedrich, Marco Durante & Michael Scholz. (2014) Modeling Cell Survival after Irradiation with Ultrasoft X Rays using the Giant Loop Binary Lesion Model. Radiation Research 181:5, pages 485-494.
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Lisa Herr, Thomas Friedrich, Marco Durante & Michael Scholz. (2014) A Model of Photon Cell Killing Based on the Spatio-Temporal Clustering of DNA Damage in Higher Order Chromatin Structures. PLoS ONE 9:1, pages e83923.
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W. Friedland & P. Kundrát. 2014. Comprehensive Biomedical Physics. Comprehensive Biomedical Physics
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D. Alloni, L.G. Mariotti & A. Ottolenghi. 2014. Comprehensive Biomedical Physics. Comprehensive Biomedical Physics
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22
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F. Tommasino, T. Friedrich, U. Scholz, G. Taucher-Scholz, M. Durante & M. Scholz. (2013) A DNA Double-Strand Break Kinetic Rejoining Model Based on the Local Effect Model. Radiation Research 180:5, pages 524-538.
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Rebecca Grün, Thomas Friedrich, Michael Krämer, Klemens Zink, Marco Durante, Rita Engenhart-Cabillic & Michael Scholz. (2013) Physical and biological factors determining the effective proton range. Medical Physics 40:11, pages 111716.
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T Friedrich, R Grün, U Scholz, T Elsässer, M Durante & M Scholz. (2013) Sensitivity analysis of the relative biological effectiveness predicted by the local effect model. Physics in Medicine and Biology 58:19, pages 6827-6849.
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R. A. El Shafie, D. Habermehl, S. Rieken, A. Mairani, L. Orschiedt, S. Brons, T. Haberer, K.-J. Weber, J. Debus & S. E. Combs. (2013) In vitro evaluation of photon and raster-scanned carbon ion radiotherapy in combination with gemcitabine in pancreatic cancer cell lines. Journal of Radiation Research 54:suppl 1, pages i113-i119.
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D. Alloni, A. Campa, W. Friedland, L. Mariotti & A. Ottolenghi. (2013) Integration of Monte Carlo Simulations with PFGE Experimental Data Yields Constant RBE of 2.3 for DNA Double-Strand Break Induction by Nitrogen Ions between 125 and 225 keV/μm LET. Radiation Research 179:6, pages 690-697.
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T T Böhlen, S Brons, M Dosanjh, A Ferrari, P Fossati, T Haberer, V Patera & A Mairani. (2012) Investigating the robustness of ion beam therapy treatment plans to uncertainties in biological treatment parameters. Physics in Medicine and Biology 57:23, pages 7983-8004.
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R Grün, T Friedrich, T Elsässer, M Krämer, K Zink, C P Karger, M Durante, R Engenhart-Cabillic & M Scholz. (2012) Impact of enhancements in the local effect model (LEM) on the predicted RBE-weighted target dose distribution in carbon ion therapy. Physics in Medicine and Biology 57:22, pages 7261-7274.
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Thomas Friedrich, Marco Durante & Michael Scholz. (2012) Modeling Cell Survival after Photon Irradiation Based on Double-Strand Break Clustering in Megabase Pair Chromatin Loops. Radiation Research 178:5, pages 385-394.
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Marco Durante. (2012) Eighth Warren K. Sinclair Keynote Address. Health Physics 103:5, pages 532-539.
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Olaf Steinsträter, Rebecca Grün, Uwe Scholz, Thomas Friedrich, Marco Durante & Michael Scholz. (2012) Mapping of RBE-Weighted Doses Between HIMAC– and LEM–Based Treatment Planning Systems for Carbon Ion Therapy. International Journal of Radiation Oncology*Biology*Physics 84:3, pages 854-860.
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T E Schmid, C Greubel, V Hable, O Zlobinskaya, D Michalski, S Girst, C Siebenwirth, E Schmid, M Molls, G Multhoff & G Dollinger. (2012) Low LET protons focused to submicrometer shows enhanced radiobiological effectiveness. Physics in Medicine and Biology 57:19, pages 5889-5907.
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M Krämer, E Scifoni, C Wälzlein & M Durante. (2012) Ion beams in radiotherapy - from tracks to treatment planning. Journal of Physics: Conference Series 373, pages 012017.
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