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Ted W. Simon, S. Stoney Simons$suffix/text()$suffix/text(), R. Julian Preston, Alan R. Boobis, Samuel M. Cohen, Nancy G. Doerrer, Penelope A. Fenner-Crisp, Tami S. McMullin, Charlene A. McQueen & J. Craig Rowlands. (2014) The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events. Critical Reviews in Toxicology 44:sup3, pages 17-43.
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John W. Wills, Alexandra S. Long, George E. Johnson, Jeffrey C. Bemis, Stephen D. Dertinger, Wout Slob & Paul A. White. (2016)
Empirical analysis of BMD metrics in genetic toxicology part II:
in vivo
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. Mutagenesis 31:3, pages 265-275.
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John W. Wills, George E. Johnson, Shareen H. Doak, Lya G. Soeteman-Hernández, Wout Slob & Paul A. White. (2016)
Empirical analysis of BMD metrics in genetic toxicology part I:
in vitro
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Andreas Zeller, Leilei Tang, Stephen D. Dertinger, Juergen Funk, Gonzalo Duran-Pacheco & Melanie Guérard. (2016)
A proposal for a novel rationale for critical effect size in dose–response analysis based on a multi-endpoint
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study with methyl methanesulfonate
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David J. Tweats, George E. Johnson, Ivan Scandale, James Whitwell & Dean B. Evans. (2016)
Genotoxicity of flubendazole and its metabolites
in vitro
and the impact of a new formulation on
in vivo
aneugenicity
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Lya G. Soeteman-Hernández, George E. Johnson & Wout Slob. (2016)
Estimating the carcinogenic potency of chemicals from the
in vivo
micronucleus test
. Mutagenesis 31:3, pages 347-358.
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Jeffrey C. Bemis, John W. Wills, Steven M. Bryce, Dorothea K. Torous, Stephen D. Dertinger & Wout Slob. (2016)
Comparison of
in vitro
and
in vivo
clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data
. Mutagenesis 31:3, pages 277-285.
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Xiaoqing Guo, Robert H. Heflich, Stacey L. Dial, Patricia A. Richter, Martha M. Moore & Nan Mei. (2016) Quantitative analysis of the relative mutagenicity of five chemical constituents of tobacco smoke in the mouse lymphoma assay. Mutagenesis 31:3, pages 287-296.
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Chad M. Thompson, Anne Bichteler, Julia E. Rager, Mina Suh, Deborah M. Proctor, Laurie C. Haws & Mark A. Harris. (2016) Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 800-801, pages 28-34.
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Kenneth T. Bogen. (2015) Linear‐No‐Threshold Default Assumptions for Noncancer and Nongenotoxic Cancer Risks: A Mathematical and Biological Critique. Risk Analysis 36:3, pages 589-604.
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Katja Brüsehafer, Bella B. Manshian, Ann T. Doherty, Zoulikha M. Zaïr, George E. Johnson, Shareen H. Doak & Gareth J. S. Jenkins. (2016) The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency. Mutagenesis 31:2, pages 171-180.
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Joanna Klapacz, Lynn H. Pottenger, Bevin P. Engelward, Christopher D. Heinen, George E. Johnson, Rebecca A. Clewell, Paul L. Carmichael, Yeyejide Adeleye & Melvin E. Andersen. (2016) Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents. Mutation Research/Reviews in Mutation Research 767, pages 77-91.
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Weihsueh A. Chiu & Wout Slob. (2015) A Unified Probabilistic Framework for Dose–Response Assessment of Human Health Effects. Environmental Health Perspectives 123:12, pages 1241-1254.
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Lya G. Soeteman-Hernández, Mick D. Fellows, George E. Johnson & Wout Slob. (2015)
Correlation of
In Vivo
Versus
In Vitro
Benchmark Doses (BMDs) Derived From Micronucleus Test Data: A Proof of Concept Study
. Toxicological Sciences 148:2, pages 355-367.
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M.M. Nijkamp, B.G.H. Bokkers, M.I. Bakker, J. Ezendam & J.E. Delmaar. (2015) Quantitative risk assessment of the aggregate dermal exposure to the sensitizing fragrance geraniol in personal care products and household cleaning agents. Regulatory Toxicology and Pharmacology 73:1, pages 9-18.
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Anne S. Kienhuis, Wout Slob, Eric R. Gremmer, Jolanda P. Vermeulen & Janine Ezendam. (2015) A Dose-Response Modeling Approach Shows That Effects From Mixture Exposure to the Skin Sensitizers Isoeugenol and Cinnamal Are in Line With Dose Addition and Not With Synergism. Toxicological Sciences 147:1, pages 68-74.
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Ilse Gosens, Ali Kermanizadeh, Nicklas Raun Jacobsen, Anke-Gabriele Lenz, Bas Bokkers, Wim H. de Jong, Petra Krystek, Lang Tran, Vicki Stone, Håkan Wallin, Tobias Stoeger & Flemming R. Cassee. (2015) Comparative Hazard Identification by a Single Dose Lung Exposure of Zinc Oxide and Silver Nanomaterials in Mice. PLOS ONE 10:5, pages e0126934.
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James T. MacGregor, Roland Frötschl, Paul A. White, Kenny S. Crump, David A. Eastmond, Shoji Fukushima, Melanie Guérard, Makoto Hayashi, Lya G. Soeteman-Hernández, Toshio Kasamatsu, Dan D. Levy, Takeshi Morita, Lutz Müller, Rita Schoeny, Maik J. Schuler, Véronique Thybaud & George E. Johnson. (2015) IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs). Mutation Research/Genetic Toxicology and Environmental Mutagenesis 783, pages 55-65.
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Richard A. Becker, Katie Paul Friedman, Ted W. Simon, M. Sue Marty, Grace Patlewicz & J. Craig Rowlands. (2015) An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept. Regulatory Toxicology and Pharmacology 71:3, pages 398-408.
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Maria A. Spassova, David J. Miller & Alexander S. Nikolov. (2015)
Kinetic Modeling Reveals the Roles of Reactive Oxygen Species Scavenging and DNA Repair Processes in Shaping the Dose-Response Curve of KBrO
3
-Induced DNA Damage
. Oxidative Medicine and Cellular Longevity 2015, pages 1-12.
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George E. Johnson, Wout Slob, Shareen H. Doak, Mick D. Fellows, Bhaskar B. Gollapudi, Robert H. Heflich, Ben J. Rees, Lya G. Soeteman-Hernández, Jatin R. Verma, John W. Wills, Gareth J. S. Jenkins & Paul A. White. (2015) New approaches to advance the use of genetic toxicology analyses for human health risk assessment. Toxicology Research 4:3, pages 667-676.
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M. Guérard, M. Baum, A. Bitsch, G. Eisenbrand, A. Elhajouji, B. Epe, M. Habermeyer, B. Kaina, H.J. Martus, S. Pfuhler, C. Schmitz, A. Sutter, A.D. Thomas, C. Ziemann & R. Froetschl. (2015) Assessment of mechanisms driving non-linear dose–response relationships in genotoxicity testing. Mutation Research/Reviews in Mutation Research 763, pages 181-201.
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