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Research Article

Chemically Induced Nephrotoxicity: Role of Metabolic Activation

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Pages 99-160 | Published online: 26 Sep 2008

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Ursula Gundert-Remy, Ulrike Bernauer, Brunhilde Blömeke, Barbara Döring, Eric Fabian, Carsten Goebel, Stefanie Hessel, Christine Jäckh, Alfonso Lampen, Franz Oesch, Ernst Petzinger, Wolfgang Völkel & Peter H. Roos. (2014) Extrahepatic metabolism at the body's internal–external interfaces. Drug Metabolism Reviews 46:3, pages 291-324.
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Emad A. Salem, Neveen A. Salem, Mostafa Kamel, Aref M. Maarouf, Nabil K. Bissada, Wayne J.G. Hellstrom & Mohmoud ElAdl. (2010) Amelioration of gentamicin nephrotoxicity by green tea extract in uninephrectomized rats as a model of progressive renal failure. Renal Failure 32:10, pages 1210-1215.
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M. Mahboob, M.K.J. Siddiqui & Kaiser Jamil. (2000) Subacute effects of a phosphorothionate pesticide on mixed function oxidases of wistar rats. Journal of Environmental Science and Health, Part B 35:6, pages 739-749.
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Pierre Raymond & Gabriel L. Plaa. (1996) Ketone Potentiation of Haloalkane-Induced Hepatotoxicity: CCl4 and Ketone Treatment on Hepatic Membrane Integrity. Journal of Toxicology and Environmental Health 49:3, pages 285-300.
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Wolfgang Dekant & Spiros Vamvakas. (1996) Biotransformation and Membrane Transport in Nephrotoxicity. Critical Reviews in Toxicology 26:3, pages 309-334.
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Pierre Raymond & GabrielL. Plaa. (1995) Ketone potentiation of haloalkane‐induced hepato‐ and nephrotoxicity. II. implication of monooxygenases. Journal of Toxicology and Environmental Health 46:3, pages 317-328.
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Piotr Czekaj, Andrzej Plewka, Marcin Kamiriski, Grazyna Nowaczyk‐Dura, Krzysztof Pawlicki & Ewa Wielgus‐Serafińska. (1994) Daily and circadian rhythms in the activity of mixed function oxidases system in rats of different age. Biological Rhythm Research 25:1, pages 67-75.
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Judy L Raucy, James C. Kraner & Jerome M. Lasker. (1993) Bioactivation of Halogenated Hydrocarbons by Cytochrome P4502E1. Critical Reviews in Toxicology 23:1, pages 1-20.
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Serina Alison Chin, John Paul Fawcett & Robert James Walker. (1992) Captopril Does Not Protect Against Renal Oxidative Injury. Renal Failure 14:4, pages 473-477.
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Ivan W. F. Davidson & Robert P. Beliles. (1991) Consideration of the Target Organ Toxicity of Trichloroethylene in Terms of Metabolite Toxicity and Pharmacokinetics. Drug Metabolism Reviews 23:5-6, pages 493-599.
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James V. Bruckner, Barbara D. Davis & Jerry N. Blancato. (1989) Metabolism, Toxicity, and Carcinogenicity of Trichloroethylene. Critical Reviews in Toxicology 20:1, pages 31-50.
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Edward A. Lock & William O. Berndt. (1988) Studies on the Mechanism of Nephrotoxicity and Nephrocarcinogenicity of Halogenated Alkenes. CRC Critical Reviews in Toxicology 19:1, pages 23-42.
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Wolfgang Dekant, Dieter Schrenk, Spyridon Vamvakas & Dietrich Henschler. (1988) Metabolism of hexachloro-1,3-butadiene in mice: in vivo and in vitro evidence for activation by glutathione conjugation. Xenobiotica 18:7, pages 803-816.
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L. R. Kao & L. S. Birnbaum. (1986) Disposition of o‐benzyl‐p‐chlorophenol in male rats. Journal of Toxicology and Environmental Health 18:3, pages 441-458.
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