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Research Article

Abundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease

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Pages 1212-1220 | Received 18 Jul 2012, Accepted 17 Oct 2012, Published online: 23 Nov 2012

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Lina Chen, Kathrin Tyryshkin, Alison Moore, David W. Scott, Christian Steidl, Yi Li, Lois E. Shepherd, Michael Rauh, Lan Deng, David Good, Shakeel Virk, Bingshu E. Chen, Susan Crocker, Tara Baetz & David P. LeBrun. (2020) Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations. Leukemia & Lymphoma 61:6, pages 1334-1344.
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Naif AlJohani, Suk-Jin Choi, Andrew G. Day, Abdulmohsen Alhejaily, Shakeel Virk, Tara Baetz & David P. LeBrun. (2018) Abundant expression of BMI1 in follicular lymphoma is associated with reduced overall survival. Leukemia & Lymphoma 59:9, pages 2211-2219.
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Shruti Bhatt, Kristopher A. Sarosiek & Izidore S. Lossos. (2017) Interleukin 21 – its potential role in the therapy of B-cell lymphomas. Leukemia & Lymphoma 58:1, pages 17-29.
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Articles from other publishers (12)

Sima Balouchi-Anaraki, Sara Mohammadsadeghi, Marzieh Norouzian, Reza Rasolmali, Abdol-Rasoul Talei, Fereshteh Mehdipour & Abbas Ghaderi. (2022) Expression of Interleukin-21 and Interleukin-21 receptor in lymphocytes derived from tumor-draining lymph nodes of breast cancer. Breast Disease 41:1, pages 373-382.
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NINO NANAVA, GIORGI GIORGOBIANI, NINO KIKODZE, SOPHIO METREVELI, TINATIN CHIKOVANI & NONA JANIKASHVILI. (2022) CORRELATIONS BETWEEN PERIPHERAL BLOOD INFLAMMATORY MARKERS AND INTERLEUKIN-21 IN PATIENTS WITH HEMATOLOGIC MALIGNANCIES. EXPERIMENTAL & CLINICAL MEDICINE GEORGIA.
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Nahum Puebla-Osorio, Paolo Strati & Sattva S. Neelapu. 2020. Follicular Lymphoma. Follicular Lymphoma 65 82 .
Lei Yan, Jing Zhang, Dong Guo, Ji Ma, Shao-Feng Shui & Xin-Wei Han. (2018) IL-21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR-125a-3p axis in gastric cancer. International Journal of Oncology.
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Yanxia Huang, Jing Zhang, Ge Wang, Xiaoyu Chen, Rui Zhang, Hui Liu & Jinshui Zhu. (2018) Oxymatrine exhibits anti-tumor activity in gastric cancer through inhibition of IL-21R-mediated JAK2/STAT3 pathway. International Journal of Immunopathology and Pharmacology 32, pages 205873841878163.
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Tommaso De Marchi, Mieke A. Timmermans, Anieta M. Sieuwerts, Marcel Smid, Maxime P. Look, Nicolai Grebenchtchikov, Fred C. G. J. Sweep, Jan G. Smits, Viktor Magdolen, Carolien H. M. van Deurzen, John A. Foekens, Arzu Umar & John W. Martens. (2017) Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer. Scientific Reports 7:1.
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Jiyu Ju, Lina Wang, Dalin Di, Weiling Xiao, Meiyu Peng, Yishuai Liu, Xiaoyan Fu, Chunling Zhao & Xuebin Qin. (2016) Adenovirus-mediated interleukin 21 gene transfer enhances antitumor immunity and reduces tumorigenicity of Hepa1–6 in mice. Oncology Letters 12:5, pages 3749-3754.
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J.I. Weberpals, M.S. Amin, B.E. Chen, D. Tu, J.N. Spaans, J.A. Squire, E.A. Eisenhauer, S. Virk, D. Ma, M. Duciaume, P. Hoskins & D.P. LeBrun. (2016) First application of the Automated QUantitative Analysis (AQUA) technique to quantify PTEN protein expression in ovarian cancer: A correlative study of NCIC CTG OV.16. Gynecologic Oncology 140:3, pages 486-493.
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Muhammad A. MirMatthew J. Maurer, Steven C. ZiesmerSusan L. Slager, Thomas HabermannWilliam R. MaconBrian K. LinkSergei SyrbuThomas WitzigJonathan W. FriedbergOliver Press, Michael LeBlanc, James R. Cerhan, Anne NovakStephen M. Ansell. (2015) Elevated serum levels of IL-2R, IL-1RA, and CXCL9 are associated with a poor prognosis in follicular lymphoma. Blood 125:6, pages 992-998.
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Michela Croce, Valentina Rigo & Silvano Ferrini. (2015) IL-21: A Pleiotropic Cytokine with Potential Applications in Oncology. Journal of Immunology Research 2015, pages 1-15.
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Abdi Ghaffari, Victoria Hoskin, Alvin Szeto, Maaike Hum, Navid Liaghati, Kanji Nakatsu, Yolanda Madarnas, Sandip Sengupta & Bruce E Elliott. (2014) A novel role for ezrin in breast cancer angio/lymphangiogenesis. Breast Cancer Research 16:5.
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Rosanne Spolski & Warren J. Leonard. (2014) Interleukin-21: a double-edged sword with therapeutic potential. Nature Reviews Drug Discovery 13:5, pages 379-395.
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