Leukemia & Lymphoma, Volume 54, Issue 6 (2013)

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Leukemia & Lymphoma, Volume 54, Issue 6 (2013)

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Commentaries on selected articles in this issue

Article
The phosphoinositide 3-kinase pathway in chronic lymphocytic leukemia: evidence for phosphatase and tensin homolog deletion on chromosome 10 deregulation
O. Giles Best & Stephen P. Mulligan
Pages: 1123-1124
Published online: 05 Dec 2012
CitationforThe phosphoinositide 3-kinase pathway in chronic lymphocytic leukemia: evidence for phosphatase and tensin homolog deletion on chromosome 10 deregulation | Full Text | References | PDF (131.7 KB) | Supplemental
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Commentary

Article Commentary
B-cell receptor signaling in chronic lymphocytic leukemia leans on Lyn
Yair Herishanu & Aaron Polliack
Pages: 1125-1126
Published online: 08 Jan 2013
CitationforB-cell receptor signaling in chronic lymphocytic leukemia leans on Lyn | Full Text | References | PDF (133.8 KB) | Supplemental
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Article Commentary
Interim positron emission tomography in early stage Hodgkin lymphoma: is there evidence for its prognostic and predictive value in patients treated with standard combined modality treatment?
Lena Specht
Pages: 1127-1128
Published online: 19 Feb 2013
CitationforInterim positron emission tomography in early stage Hodgkin lymphoma: is there evidence for its prognostic and predictive value in patients treated with standard combined modality treatment? | Full Text | References | PDF (128.4 KB) | Supplemental
  • 576 Views
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Research Article

Article
The elusive predisposing polymorphism: MDR1 and lymphoma
Deborah Rund
Pages: 1129-1130
Published online: 10 Dec 2012
CitationforThe elusive predisposing polymorphism: MDR1 and lymphoma | Full Text | References | PDF (136.1 KB)
  • 405 Views
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Commentary

Article Commentary
Free light chain assay: doing a “good job” in Job's syndrome
Tamar Tadmor
Pages: 1131-1132
Published online: 08 Mar 2013
CitationforFree light chain assay: doing a “good job” in Job's syndrome | Full Text | References | PDF (127.6 KB) | Supplemental
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Article Commentary
Pre-transplant serum ferritin is prognostic but is it useful?
Andrew S. Artz & Koen van Besien
Pages: 1133-1134
Published online: 08 Jan 2013
CitationforPre-transplant serum ferritin is prognostic but is it useful? | Full Text | References | PDF (130.7 KB) | Supplemental
  • 524 Views
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Reviews

Review Article
Extramedullary multiple myeloma
Matthew Weinstock & Irene M. Ghobrial
Pages: 1135-1141
Published online: 31 Dec 2012
AbstractforExtramedullary multiple myeloma | Full Text | References | PDF (289 KB) | Supplemental
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Review Article

Review Article
Geography, ethnicity and “roots” in chronic lymphocytic leukemia
Rosa Ruchlemer & Aaron Polliack
Pages: 1142-1150
Published online: 10 Dec 2012
AbstractforGeography, ethnicity and “roots” in chronic lymphocytic leukemia | Full Text | References | PDF (195.1 KB) | Supplemental
  • 697 Views
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Review Article
Advances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop
Richard A. van Etten, Michael Mauro, Jerald P. Radich, John M. Goldman, Giuseppe Saglio, Catriona Jamieson, Simona Soverini, Carlo Gambacorti-Passerini, Rüdiger Hehlmann, Giovanni Martinelli, Danilo Perrotti, David T. Scadden, Tomasz Skorski, Ayalew Tefferi & Tariq I. Mughal
Pages: 1151-1158
Published online: 10 Dec 2012
AbstractforAdvances in the biology and therapy of chronic myeloid leukemia: proceedings from the 6th Post-ASH International Chronic Myeloid Leukemia and Myeloproliferative Neoplasms Workshop | Full Text | References | PDF (201.2 KB) | Supplemental
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Original Articles: Clinical

Article
Low expression level of phosphatase and tensin homolog deleted on chromosome ten predicts poor prognosis in chronic lymphocytic leukemia
Zhi-Jian Zou, Run Zhang, Lei Fan, Li Wang, Cheng Fang, Li-Na Zhang, Shu Yang, Yuan-Yuan Li, Jian-Yong Li & Wei Xu
Pages: 1159-1164
Published online: 16 Oct 2012
AbstractforLow expression level of phosphatase and tensin homolog deleted on chromosome ten predicts poor prognosis in chronic lymphocytic leukemia | Full Text | References | PDF (275.2 KB) | Supplemental
  • 225 Views
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Research Article

Article
Expression levels of Lyn, Syk, PLCγ2 and ERK in patients with chronic lymphocytic leukemia, and higher levels of Lyn are associated with a shorter treatment-free survival
Yin-Hua Wang, Lei Fan, Li Wang, Run Zhang, Zhi-Jian Zou, Cheng Fang, Li-Na Zhang, Jian-Yong Li & Wei Xu
Pages: 1165-1170
Published online: 02 Nov 2012
AbstractforExpression levels of Lyn, Syk, PLCγ2 and ERK in patients with chronic lymphocytic leukemia, and higher levels of Lyn are associated with a shorter treatment-free survival | Full Text | References | PDF (194.7 KB) | Supplemental
  • 402 Views
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Article
ZAP-70 expression and proliferative activity in chronic lymphocytic leukemia
Violeta Šoljić, Renata Beljan Perak, Katarina Vukojević, Mirna Saraga-Babić, Pero Bubalo, Dragana Karan, Jelena Todorović & Drago Batinić
Pages: 1171-1176
Published online: 19 Nov 2012
AbstractforZAP-70 expression and proliferative activity in chronic lymphocytic leukemia | Full Text | References | PDF (310.8 KB) | Supplemental
  • 191 Views
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Article
BRAF mutations in chronic lymphocytic leukemia
Billy Michael Chelliah Jebaraj, Dirk Kienle, Andreas Bühler, Dirk Winkler, Hartmut Döhner, Stephan Stilgenbauer & Thorsten Zenz
Pages: 1177-1182
Published online: 20 Nov 2012
AbstractforBRAF mutations in chronic lymphocytic leukemia | Full Text | References | PDF (451.1 KB) | Supplemental
  • 939 Views
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Article
Interim positron emission tomography and clinical outcome in patients with early stage Hodgkin lymphoma treated with combined modality therapy
Andrea Riccardo Filippi, Angela Botticella, Marilena Bellò, Barbara Botto, Anna Castiglione, Paolo Gavarotti, Daniela Gottardi, Guido Parvis, Gianni Bisi, Alessandro Levis, Umberto Vitolo & Umberto Ricardi
Pages: 1183-1187
Published online: 01 Nov 2012
AbstractforInterim positron emission tomography and clinical outcome in patients with early stage Hodgkin lymphoma treated with combined modality therapy | Full Text | References | PDF (189.2 KB) | Supplemental
  • 302 Views
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Article
MDR1 polymorphisms associated with risk and survival in diffuse large B-cell lymphoma
Li-Li Hu, Bingyun Yu & Jine Yang
Pages: 1188-1193
Published online: 20 Nov 2012
AbstractforMDR1 polymorphisms associated with risk and survival in diffuse large B-cell lymphoma | Full Text | References | PDF (238.6 KB) | Supplemental
  • 186 Views
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Article
Gemcitabine, oxaliplatin and dexamethasone as salvage treatment for elderly patients with refractory and relapsed peripheral T-cell lymphoma
Yi-yun Yao, Yong Tang, Qi Zhu, Yan Zhuang, Yi-min Cheng, Lei Wang & Li-fang Zou
Pages: 1194-1200
Published online: 19 Nov 2012
AbstractforGemcitabine, oxaliplatin and dexamethasone as salvage treatment for elderly patients with refractory and relapsed peripheral T-cell lymphoma | Full Text | References | PDF (246.1 KB) | Supplemental
  • 677 Views
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Article
Immunomorphologic profile and Epstein–Barr virus status of a cohort of 35 cases of extranodal natural killer/T-cell lymphoma, nasal type of upper aerodigestive tract from a tertiary care center in South India
Amit Bugalia, Marie Therese Manipadam & Sheila Nair
Pages: 1201-1207
Published online: 26 Nov 2012
AbstractforImmunomorphologic profile and Epstein–Barr virus status of a cohort of 35 cases of extranodal natural killer/T-cell lymphoma, nasal type of upper aerodigestive tract from a tertiary care center in South India | Full Text | References | PDF (443 KB) | Supplemental
  • 176 Views
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Article
Indolent non-Hodgkin lymphoma primarily involving the hard palate: outcome following radiotherapy
Sarah A. Milgrom & Joachim Yahalom
Pages: 1208-1211
Published online: 20 Nov 2012
AbstractforIndolent non-Hodgkin lymphoma primarily involving the hard palate: outcome following radiotherapy | Full Text | References | PDF (201.8 KB) | Supplemental
  • 200 Views
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Article
Abundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease
Brianne Wood, Soma Sikdar, Suk Jin Choi, Shakeel Virk, Abdulmohsen Alhejaily, Tara Baetz & David P. LeBrun
Pages: 1212-1220
Published online: 23 Nov 2012
AbstractforAbundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease | Full Text | References | PDF (728.3 KB) | Supplemental
  • 333 Views
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Article
Body mass index, height and risk of lymphoid neoplasms in a large United States cohort
Alpa V. Patel, W. Ryan Diver, Lauren R. Teras, Brenda M. Birmann & Susan M. Gapstur
Pages: 1221-1227
Published online: 24 Jan 2013
AbstractforBody mass index, height and risk of lymphoid neoplasms in a large United States cohort | Full Text | References | PDF (236.7 KB) | Supplemental
  • 503 Views
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Article
Outcome of relapse after allogeneic stem cell transplant in patients with acute myeloid leukemia
Raynier Devillier, Roberto Crocchiolo, Anne Etienne, Thomas Prebet, Aude Charbonnier, Sabine Fürst, Jean El-Cheikh, Evelyne D'Incan, Jérôme Rey, Catherine Faucher, Didier Blaise & Norbert Vey
Pages: 1228-1234
Published online: 19 Nov 2012
AbstractforOutcome of relapse after allogeneic stem cell transplant in patients with acute myeloid leukemia | Full Text | References | PDF (315.7 KB) | Supplemental
  • 551 Views
  • 41 CrossRef citations
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Article
Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease
Courtney D. DiNardo, Alexis Ogdie, Elizabeth O. Hexner, Noelle V. Frey, Alison W. Loren & Selina M. Luger
Pages: 1235-1241
Published online: 19 Feb 2013
AbstractforCharacteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease | Full Text | References | PDF (181.3 KB) | Supplemental
  • 218 Views
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Article
Immune reconstitution after combined haploidentical and umbilical cord blood transplant
Nitin Jain, Hongtao Liu, Andrew S. Artz, John Anastasi, Olatoyosi Odenike, Lucy A. Godley, Loren Joseph, Susana Marino, Justin Kline, Vu Nguyen, Viviane Schouten, Rangesh Kunnavakkam, Richard A. Larson, Wendy Stock, Jodie Ulaszek, Peter A. Savage, Amittha Wickrema & Koen van Besien
Pages: 1242-1249
Published online: 01 Mar 2013
AbstractforImmune reconstitution after combined haploidentical and umbilical cord blood transplant | Full Text | References | PDF (397 KB) | Supplemental
  • 649 Views
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Article
Clinical characteristics and outcome associated with pandemic (2009) H1N1 influenza infection in patients with hematologic malignancies: a retrospective cohort study
Brian J. Minnema, Shahid Husain, Tony Mazzulli, Seyed Mohammedmehdi Hosseini-Mogaddam, Mehul Patel, Joseph Brandwein, Donna Reece, Jeffrey H. Lipton & Coleman Rotstein
Pages: 1250-1255
Published online: 19 Nov 2012
AbstractforClinical characteristics and outcome associated with pandemic (2009) H1N1 influenza infection in patients with hematologic malignancies: a retrospective cohort study | Full Text | References | PDF (177.4 KB) | Supplemental
  • 222 Views
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Article
Individualized tumor response testing profile has a prognostic value in childhood acute leukemias: multicenter non-interventional long-term follow-up study
Magdalena Piatkowska, Jan Styczynski, Beata Kolodziej, Beata Kurylo-Rafinska, Malgorzata Kubicka, Monika Pogorzala, Krzysztof Czyzewski, Robert Debski, Michal Matysiak, Iwona Malinowska, Walentyna Balwierz, Edyta Juraszewska, Jacek Wachowiak, Benigna Konatkowska, Maria Wieczorek, Igor Olejnik, Maryna Krawczuk-Rybak, Marta Kuzmicz, Jerzy Kowalczyk, Maria Jolanta Stefaniak, Wanda Badowska, Tomasz Szczepanski, Renata Tomaszewska, Elżbieta Adamkiewicz-Drozynska, Lucyna Maciejka-Kapuscinska, Grazyna Sobol, Agnieszka Mizia-Malarz & Mariusz Wysocki
Pages: 1256-1262
Published online: 21 Nov 2012
AbstractforIndividualized tumor response testing profile has a prognostic value in childhood acute leukemias: multicenter non-interventional long-term follow-up study | Full Text | References | PDF (227.3 KB) | Supplemental
  • 164 Views
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Article
Comparison of complication rates of Hickman® catheters versus peripherally inserted central catheters in patients with acute myeloid leukemia undergoing induction chemotherapy
Ming Y. Lim, Aref Al-Kali, Aneel A. Ashrani, Kebede H. Begna, Michelle A. Elliott, William J. Hogan, C. Christopher Hook, Scott H. Kaufmann, Louis Letendre, Mark R. Litzow, Mrinal S. Patnaik, Animesh Pardanani, Ayalew Tefferi, Alexandra P. Wolanskyj, Diane E. Grill & Rajiv K. Pruthi
Pages: 1263-1267
Published online: 19 Nov 2012
AbstractforComparison of complication rates of Hickman® catheters versus peripherally inserted central catheters in patients with acute myeloid leukemia undergoing induction chemotherapy | Full Text | References | PDF (173.3 KB) | Supplemental
  • 756 Views
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Original Articles: Research

Article
Effects of Toll-like receptor 7 and Toll-like receptor 9 signaling stimulators and inhibitors on chronic lymphocytic leukemia cells ex vivo and their interactions with cladribine
Anna Wolska, Barbara Cebula-Obrzut, Piotr Smolewski & Tadeusz Robak
Pages: 1268-1278
Published online: 20 Nov 2012
AbstractforEffects of Toll-like receptor 7 and Toll-like receptor 9 signaling stimulators and inhibitors on chronic lymphocytic leukemia cells ex vivo and their interactions with cladribine | Full Text | References | PDF (524.5 KB) | Supplemental
  • 348 Views
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Research Article

Article
Mechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance
Aylin Camgoz, Emel Basak Gencer, Ali Ugur Ural & Yusuf Baran
Pages: 1279-1287
Published online: 20 Nov 2012
AbstractforMechanisms responsible for nilotinib resistance in human chronic myeloid leukemia cells and reversal of resistance | Full Text | References | PDF (719.3 KB) | Supplemental
  • 673 Views
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Article
Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia
Rebecca J. Watters, Todd E. Fox, Su-Fern Tan, Sriram Shanmugavelandy, Jacob E. Choby, Kathleen Broeg, Jason Liao, Mark Kester, Myles C. Cabot, Thomas P. Loughran & Xin Liu
Pages: 1288-1296
Published online: 31 Dec 2012
AbstractforTargeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia | Full Text | References | PDF (448.9 KB) | Supplemental
  • 282 Views
  • 28 CrossRef citations
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Article
Combined immunophenotyping and fluorescence in situ hybridization with chromosome-specific DNA probes allows quantification and differentiation of ex vivo generated dendritic cells, leukemia-derived dendritic cells and clonal leukemic cells in patients with acute myeloid leukemia
Andreas Kremser, Stefanie Kufner, Elke Konhaeuser, Tanja Kroell, Andreas Hausmann, Johanna Tischer, Hans-Jochem Kolb, Horst Zitzelsberger & Helga Schmetzer
Pages: 1297-1308
Published online: 26 Dec 2012
AbstractforCombined immunophenotyping and fluorescence in situ hybridization with chromosome-specific DNA probes allows quantification and differentiation of ex vivo generated dendritic cells, leukemia-derived dendritic cells and clonal leukemic cells in patients with acute myeloid leukemia | Full Text | References | PDF (385.1 KB) | Supplemental
  • 172 Views
  • 6 CrossRef citations
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Article
Regulation of expression of ABCB1 and LRP genes by mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and its role in generation of side population cells in canine lymphoma cell lines
Hirotaka Tomiyasu, Manabu Watanabe, Yuko Goto-Koshino, Yasuhito Fujino, Koichi Ohno, Sumio Sugano & Hajime Tsujimoto
Pages: 1309-1315
Published online: 22 Dec 2012
AbstractforRegulation of expression of ABCB1 and LRP genes by mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and its role in generation of side population cells in canine lymphoma cell lines | Full Text | References | PDF (398.9 KB) | Supplemental
  • 368 Views
  • 16 CrossRef citations
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Letters to the Editor

Letter
Serum free light chains as predictors of lymphomagenesis in patients with autosomal dominant hyper-immunoglobulin E syndrome (Job's syndrome)
Elisabet E. Manasanch, Alexandra F. Freeman, Stefania Pittaluga, Rene Costello, Steven M. Holland & Ola Landgren
Pages: 1316-1317
Published online: 16 Nov 2012
CitationforSerum free light chains as predictors of lymphomagenesis in patients with autosomal dominant hyper-immunoglobulin E syndrome (Job's syndrome) | Full Text | References | PDF (163.2 KB) | Supplemental
  • 161 Views
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Letter

Letter
Multicenter validation of scoring system of pre-transplant serum ferritin and disease risk in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic hematopoietic stem cell transplant
Takayoshi Tachibana, Masatsugu Tanaka, Etsuko Yamazaki, Ayumi Numata, Hirotaka Takasaki, Hideyuki Kuwabara, Katsumichi Fujimaki, Rika Sakai, Hiroyuki Fujita, Shin Fujisawa, Atsuo Maruta, Yoshiaki Ishigatsubo & Heiwa Kanamori
Pages: 1318-1320
Published online: 01 Nov 2012
First Page PreviewforMulticenter validation of scoring system of pre-transplant serum ferritin and disease risk in patients with acute myeloid leukemia and myelodysplastic syndrome after allogeneic hematopoietic stem cell transplant | Full Text | References | PDF (158.5 KB) | Supplemental
  • 171 Views
  • 5 CrossRef citations
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Letter
Cerebral Hodgkin lymphoma causing leptomeningeal foam cell vasculopathy with cerebral infarction
Julie Lokan, Laurence Galea, Ashwini Arumugaswamy & Andrew Grigg
Pages: 1321-1323
Published online: 14 Nov 2012
First Page PreviewforCerebral Hodgkin lymphoma causing leptomeningeal foam cell vasculopathy with cerebral infarction | Full Text | References | PDF (305.1 KB) | Supplemental
  • 154 Views
  • 6 CrossRef citations
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Letter
Complete remission of multiple myeloma associated scleredema after bortezomib-based treatment
Petr Szturz, Zdeněk Adam, Vladimír Vašků, Josef Feit, Marta Krejčí, Luděk Pour, Roman Hájek & Jiří Mayer
Pages: 1324-1326
Published online: 15 Nov 2012
First Page PreviewforComplete remission of multiple myeloma associated scleredema after bortezomib-based treatment | Full Text | References | PDF (185.8 KB) | Supplemental
  • 245 Views
  • 14 CrossRef citations
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Letter
Bendamustine can severely impair T-cell immunity against cytomegalovirus
Toru Hosoda, Akihiro Yokoyama, Mie Yoneda, Ryusuke Yamamoto, Kota Ohashi, Toshiya Kagoo, Hironori Ueno, Saigen Boku & Takahiro Yano
Pages: 1327-1328
Published online: 15 Nov 2012
CitationforBendamustine can severely impair T-cell immunity against cytomegalovirus | Full Text | References | PDF (132.1 KB) | Supplemental
  • 425 Views
  • 33 CrossRef citations
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Letter
Incidence and outcomes of invasive fungal disease in adult patients with acute lymphoblastic leukemia treated with hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone: implications for prophylaxis
Andrea Henden, Kirk Morris, Natasha Truloff, Midori Nakagaki & Glen A. Kennedy
Pages: 1329-1331
Published online: 15 Nov 2012
First Page PreviewforIncidence and outcomes of invasive fungal disease in adult patients with acute lymphoblastic leukemia treated with hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone: implications for prophylaxis | Full Text | References | PDF (139.8 KB) | Supplemental
  • 412 Views
  • 21 CrossRef citations
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Letter
Guillain–Barré syndrome after human herpesvirus-6 reactivation in unrelated hematopoietic stem cell transplantation
Eugenia Piras, Giovanni Caocci, Valentina Pisano, Federica Orrù, Francesca Murgia, Marco Sanna, Adriana Vacca & Giorgio La Nasa
Pages: 1332-1333
Published online: 04 Mar 2013
CitationforGuillain–Barré syndrome after human herpesvirus-6 reactivation in unrelated hematopoietic stem cell transplantation | Full Text | References | PDF (138.9 KB) | Supplemental
  • 165 Views
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Letter
Hepatosplenic αβ T-cell lymphoma arising after long-term azathioprine therapy successfully treated with allogeneic bone marrow transplant
Sandra Bašić Kinda, Nadira Duraković, Snježana Dotlić, Ranka Serventi Seiwerth, Sanja Davidović Mrsić, Klara Dubravčić & Igor Aurer
Pages: 1334-1335
Published online: 26 Nov 2012
CitationforHepatosplenic αβ T-cell lymphoma arising after long-term azathioprine therapy successfully treated with allogeneic bone marrow transplant | Full Text | References | PDF (190.3 KB) | Supplemental
  • 227 Views
  • 5 CrossRef citations
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Letter
Rapid detection of DNMT3A R882 codon mutations allows early identification of poor risk patients with acute myeloid leukemia
John N. Brewin, Gillian A. Horne, Kathrin E. Bisling, Helen J. Stewart & Timothy J. Chevassut
Pages: 1336-1339
Published online: 01 Nov 2012
First Page PreviewforRapid detection of DNMT3A R882 codon mutations allows early identification of poor risk patients with acute myeloid leukemia | Full Text | References | PDF (191.2 KB) | Supplemental
  • 246 Views
  • 10 CrossRef citations
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Letter
Development of progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma 13 years after treatment with cladribine
Martin Berghoff, Anne Schänzer, Gerhard C. Hildebrandt, Benjamin Dassinger, Gothje Klappstein, Manfred Kaps, Elke R. Gizewski, Till Acker & Astrid Grams
Pages: 1340-1342
Published online: 20 Nov 2012
First Page PreviewforDevelopment of progressive multifocal leukoencephalopathy in a patient with non-Hodgkin lymphoma 13 years after treatment with cladribine | Full Text | References | PDF (191.3 KB) | Supplemental
  • 182 Views
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Correspondence

Article
Quantitative bead-based assay for detection of JAK2 exon 12 mutations
Velizar Shivarov, Milena Ivanova, Slavyana Yaneva, Nina Petkova, Evgueniy Hadjiev & Elissaveta Naumova
Pages: 1343-1344
Published online: 30 Nov 2012
CitationforQuantitative bead-based assay for detection of JAK2 exon 12 mutations | Full Text | References | PDF (177.9 KB) | Supplemental
  • 108 Views
  • 9 CrossRef citations
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