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Research Article

The Role of Fixed-Dose Combination Therapy with Drugs that Target the Renin-Angiotensin System in the Hypertension Paradigm

Pages 35-42 | Received 27 Aug 2008, Accepted 02 Nov 2008, Published online: 10 Feb 2010

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Natalie Schellack & Lucille Malan. (2014) An overview of fixed-dose combinations of antihypertensive drugs in South Africa. South African Family Practice 56:4, pages 206-211.
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Sripal Bangalore & Ludwin Ley. (2012) Improving treatment adherence to antihypertensive therapy: the role of single-pill combinations. Expert Opinion on Pharmacotherapy 13:3, pages 345-355.
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L. Breitscheidel, B. Ehlken, K. Kostev, M. S. A. Oberdiek, A. Sandberg & R. E. Schmieder. (2012) Real-life treatment patterns, compliance, persistence, and medication costs in patients with hypertension in Germany. Journal of Medical Economics 15:1, pages 155-165.
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R Kreutz. (2011) Olmesartan/amlodipine: a review of its use in the management of hypertension. Vascular Health and Risk Management 7, pages 183-192.
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Tomasz Stompór, Maria Napora & Artur Olszewski. (2011) Renoprotective effects of benazepril: current perspective. Expert Review of Cardiovascular Therapy 9:6, pages 663-673.
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Vivencio Barrios & Carlos Escobar. (2010) Antihypertensive and organ-protective effects of benazepril. Expert Review of Cardiovascular Therapy 8:12, pages 1653-1671.
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Hae-Young Lee, Seok-Yeon Kim, Kee-Joon Choi, Byung-Su Yoo, Dong-Hun Cha, Hae Ok Jung, Dong-Ryeol Ryu, Joon Hyouk Choi, Kwang Je Lee, Tae Ho Park, Ju Hyeon Oh, Sang Min Kim, Ji-Yong Choi, Kye Hun Kim, Jaemin Shim, Woo-Shik Kim, Si-Wan Choi, Dae-Gyun Park, Pil-Sang Song, Taek-Jong Hong, Moo-Yong Rhee, Seung-Woon Rha & Seung Woo Park. (2017) A Randomized, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and the Tolerability of a Triple Combination of Amlodipine/Losartan/Rosuvastatin in Patients With Comorbid Essential Hypertension and Hyperlipidemia. Clinical Therapeutics 39:12, pages 2366-2379.
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Stefano Omboni, Ettore Malacco, Claudio Napoli, Pietro Amedeo Modesti, Athanasios Manolis, Gianfranco Parati, Enrico Agabiti-Rosei & Claudio Borghi. (2017) Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized “Z” Studies. Advances in Therapy 34:4, pages 784-798.
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Seok-Min Kang, Jong-Chan Youn, Shung Chull Chae, Chang Gyu Park, Joo Young Yang, Moo Hyun Kim, Taek Jong Hong, Cheol Ho Kim, Jae Joong Kim, Dong Gu Shin, Jin Won Jung, Jung Han Yoon, Si Hoon Park, Jun Kwon & Seung Yun Cho. (2011) Comparative Efficacy and Safety Profile of Amlodipine 5 mg/Losartan 50 mg Fixed-Dose Combination and Amlodipine 10 mg Monotherapy in Hypertensive Patients Who Respond Poorly to Amlodipine 5 mg Monotherapy: An 8-Week, Multicenter, Randomized, Double-Blind Phase III Noninferiority Study. Clinical Therapeutics 33:12, pages 1953-1963.
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O Suzuki, H Ishii & S Kobayashi. (2011) Effects of an Angiotensin 2 Receptor Blocker plus Diuretic Combination Drug in Chronic Heart Failure Complicated by Hypertension. Journal of International Medical Research 39:4, pages 1420-1426.
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Jie Zhao, Yue Cui, Anhe Wang, Jinbo Fei, Yang Yang & Junbai Li. (2010) Side Effect Reduction of Encapsulated Hydrocortisone Crystals by Insulin/Alginate Shells. Langmuir 27:4, pages 1499-1504.
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