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Original Article

The role of protamine amount in the transfection performance of cationic SLN designed as a gene nanocarrier

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Pages 1-10 | Received 06 Apr 2011, Accepted 06 Sep 2011, Published online: 09 Nov 2011

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Xiaolei Zhang, Tao Lu, Yanhui Ma, Rui Li, Yingxin Pang, Hongluan Mao & Peishu Liu. (2020) Novel Nanocomplexes Targeting STAT3 Demonstrate Promising Anti-Ovarian Cancer Effects in vivo. OncoTargets and Therapy 13, pages 5069-5082.
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Natalia Teresa Jarzebska, Severin Lauchli, Christoph Iselin, Lars E French, Pal Johansen, Emmanuella Guenova, Thomas M Kündig & Steve Pascolo. (2020) Functional differences between protamine preparations for the transfection of mRNA. Drug Delivery 27:1, pages 1231-1235.
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Sai-Nan He, Yun-Long Li, Jing-Jing Yan, Wei Zhang, Yong-Zhong Du, He-Yong Yu, Fu-Qiang Hu & Hong Yuan. (2013) Ternary nanoparticles composed of cationic solid lipid nanoparticles, protamine, and DNA for gene delivery. International Journal of Nanomedicine 8, pages 2859-2869.
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David Standing, Emma Feess, Satvik Kodiyalam, Michael Kuehn, Zachary Hamel, Jaimie Johnson, Sufi Mary Thomas & Shrikant Anant. (2023) The Role of STATs in Ovarian Cancer: Exploring Their Potential for Therapy. Cancers 15:9, pages 2485.
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Sankha Bhattacharya, Satyam Sharma & Bhupendra G. Prajapati. (2022) Development of D-α-Tocopherol polyethylene glycol 1000 succinate fabricated nanostructural lipid carrier of sorafenib tosylate for metastatic colorectal targeting application: Stability, physical characterization, cytotoxicity, and apoptotic studies against SW48 cells PTEN. Frontiers in Oncology 12.
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G. Puras, G. Martínez-Navarrete, M. Mashal, J. Zárate, M. Agirre, E. Ojeda, S. Grijalvo, R. Eritja, A. Diaz-Tahoces, M. Avilés-Trigueros, E. Fernández & J. L. Pedraz. (2015) Protamine/DNA/Niosome Ternary Nonviral Vectors for Gene Delivery to the Retina: The Role of Protamine. Molecular Pharmaceutics 12:10, pages 3658-3671.
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Patrícia Severino, Marcelo Szymanski, Marianna Favaro, Adriano R. Azzoni, Marco V. Chaud, Maria Helena A. Santana, Amélia M. Silva & Eliana B. Souto. (2015) Development and characterization of a cationic lipid nanocarrier as non-viral vector for gene therapy. European Journal of Pharmaceutical Sciences 66, pages 78-82.
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Erica Andreozzi, Peter Wang, Anthony Valenzuela, Chuqiao Tu, Fredric Gorin, Marc Dhenain & Angelique Louie. (2013) Size-Stable Solid Lipid Nanoparticles Loaded with Gd-DOTA for Magnetic Resonance Imaging. Bioconjugate Chemistry 24:9, pages 1455-1467.
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Ana del Pozo-RodríguezDiego DelgadoAlicia R. GascónMaria Ángeles Solinís. (2013) Lipid Nanoparticles as Drug/Gene Delivery Systems to the Retina. Journal of Ocular Pharmacology and Therapeutics 29:2, pages 173-188.
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Surendra Nimesh. 2013. Gene Therapy. Gene Therapy 237 258 .
Eleonora Vighi, Monica Montanari, Miriam Hanuskova, Valentina Iannuccelli, Gilberto Coppi & Eliana Leo. (2013) Design flexibility influencing the in vitro behavior of cationic SLN as a nonviral gene vector. International Journal of Pharmaceutics 440:2, pages 161-169.
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