Citations (57)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Qi Pan, Jing Xu, Cen-Jin Wen, Yu-Yan Xiong, Zhao-Ting Gong & Yue-Jin Yang. (2021) Nanoparticles: Promising Tools for the Treatment and Prevention of Myocardial Infarction. International Journal of Nanomedicine 16, pages 6719-6747.
Read now
Read now
Tamer M. Shehata & Mahmoud M. Ibrahima. (2019) BÜCHI nano spray dryer B-90: a promising technology for the production of metformin hydrochloride-loaded alginate–gelatin nanoparticles. Drug Development and Industrial Pharmacy 45:12, pages 1907-1914.
Read now
Read now
Hong-Kyun Kim & Young-Seok Park. (2017) Plasma concentration of metformin and dexamethasone after administration through Osseogate. Drug Delivery 24:1, pages 437-442.
Read now
Read now
Chinu Sachdeva, Neeraj Mishra & Saurabh Sharma. (2016) Development and characterization of enteric-coated microparticles of biochanin A for their beneficial pharmacological potential in estrogen deficient-hypertension. Drug Delivery 23:6, pages 2044-2057.
Read now
Read now
Articles from other publishers (53)
Yang Xia, Chang Li, Yefeng Qin, Wei Zhang, Chengwei Wu & Mingzhu Li. (2024) Zero-order Release of Metformin in Polyacrylamide Hydrogel. Journal of Drug Delivery Science and Technology 91, pages 105161.
Crossref
Crossref
Yifei Wang, Wei Song, Yiming Li, Zhekun Zhou, Chenkai Li, Weilin Yu & Yaohua He. (2023) Metformin-loaded PLGA microspheres combined with an in situ-formed injectable SA/BG hydrogel alleviate rotator cuff muscle degeneration. Materials Today Bio 23, pages 100874.
Crossref
Crossref
Priyanka Chauhan, Himanshu Paliwal, Chetan Singh Chauhan & Ankit Paliwal. (2023) PLGA-based microspheres loaded with metformin hydrochloride: Modified double emulsion method preparation, optimization, characterization, and in vitro evaluation. Annales Pharmaceutiques Françaises 81:6, pages 997-1006.
Crossref
Crossref
Xiaopin Hua, Xiuli Zhang, Qiaohua Peng, Juanhong Wu, Sangsang Tang, Chenxi Lin & Jian Shen. (2023) A pH-responsive nanocarrier synergistically activate tumor immunotherapy by promoting pyroptosis and immune checkpoint blocking. Colloid and Interface Science Communications 57, pages 100751.
Crossref
Crossref
Zhiru Zou, Shan Wen, Qi Yu, Yingqiao Li, Jinyu An, Ying Xiong, Qian Wu, Le Tong, Chao Wu, Xifan Mei & He Tian. (2023) Nanoscale Glutathione-Functionalized Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Loaded with Metformin for the Treatment of Spinal Cord Injury. ACS Applied Nano Materials 6:20, pages 19257-19270.
Crossref
Crossref
Zahra Barmoudeh, Mohamad Hassan Fouani, Zahra Moslemi, Mahdokht Azizi, Amir Hossein Doustimotlagh & Hassan Bardania. (2023) Melatonin and metformin co-loaded nanoliposomes efficiently attenuate liver damage induced by bile duct ligation in rats. Naunyn-Schmiedeberg's Archives of Pharmacology.
Crossref
Crossref
Afife Busra Ugur Kaplan, Meltem Cetin, Cemil Bayram, Serkan Yildirim, Ali Taghizadehghalehjoughi & Ahmet Hacimuftuoglu. (2023) In Vivo Evaluation of Nanoemulsion Formulations for Metformin and Repaglinide Alone and Combination. Journal of Pharmaceutical Sciences 112:5, pages 1411-1426.
Crossref
Crossref
Afife Busra Ugur Kaplan & Meltem Cetin. (2023) Development of a Simple Isocratic HPLC-UV Method for the Simultaneous Analysis of Repaglinide and Metformin Hydrochloride in Nanoemulsion Formulations and Commercial Tablets. Pharmaceutical Chemistry Journal 57:2, pages 318-326.
Crossref
Crossref
Vikash Chaturvedi, Disha Sharma, Vaishnavi Pandey, Sudhanshu Mishra, Shobhit Prakash Shrivastava, Akanksha Sharma & Rishabha Malviya. (2023) Polycystic Ovarian Syndrome: Current Situation of Female Hormonal Disorder. Current Women s Health Reviews 19:2.
Crossref
Crossref
Fan Zhang, Wei Liu, Yonggui Long & Huali Peng. (2023) Targeted Delivery of Metformin Against Lung Cancer Cells Via Hyaluronan-Modified Mesoporous Silica Nanoparticles. Applied Biochemistry and Biotechnology.
Crossref
Crossref
Mohammad Javad Javid-Naderi, Ali Mahmoudi, Prashant Kesharwani, Tannaz Jamialahmadi & Amirhossein Sahebkar. (2023) Recent advances of nanotechnology in the treatment and diagnosis of polycystic ovary syndrome. Journal of Drug Delivery Science and Technology 79, pages 104014.
Crossref
Crossref
Kumar Venkatesan, Saad M. Alshahrani, Amal M. Alsubaiyel, Maram H. Abduljabbar, Manal E. Alosaimi, Maria Grishina & Saeed Shirazian. (2023) Experimental - Theoretical approach for determination of Metformin solubility in supercritical carbon dioxide: Thermodynamic modeling. Case Studies in Thermal Engineering 41, pages 102649.
Crossref
Crossref
Jyosna Doniparthi, Suryaprakash Reddy Chappidi & E. Bhargav. 2023. Alginate Biomaterial. Alginate Biomaterial
19
59
.
Wenjie Lu, Lingfei Yu, Lujun Wang, Songlin Liu, Manman Li, Zijun Wu, Shengqi Chen, Rongfeng Hu & Haiping Hao. (2022) Metformin Hydrochloride Mucosal Nanoparticles-Based Enteric Capsule for Prolonged Intestinal Residence Time, Improved Bioavailability, and Hypoglycemic Effect. AAPS PharmSciTech 24:1.
Crossref
Crossref
Tilahun Ayane Debele & Yoonjee Park. (2022) Application of Nanoparticles: Diagnosis, Therapeutics, and Delivery of Insulin/Anti-Diabetic Drugs to Enhance the Therapeutic Efficacy of Diabetes Mellitus. Life 12:12, pages 2078.
Crossref
Crossref
Wenjie Zhong, Xinyan Wang, Lanxin Yang, Yue Wang, Qingyue Xiao, Simin Yu, Richard D. Cannon, Yan Bai, Chuangwei Zhang, Duanjing Chen, Ping Ji, Xiang Gao & Jinlin Song. (2022) Nanocarrier-Assisted Delivery of Metformin Boosts Remodeling of Diabetic Periodontal Tissue via Cellular Exocytosis-Mediated Regulation of Endoplasmic Reticulum Homeostasis. ACS Nano 16:11, pages 19096-19113.
Crossref
Crossref
Daniil A. Rusanov, Jiaying Zou & Maria V. Babak. (2022) Biological Properties of Transition Metal Complexes with Metformin and Its Analogues. Pharmaceuticals 15:4, pages 453.
Crossref
Crossref
Elaine Chow, Aimin Yang, Colin H. L. Chung & Juliana C. N. Chan. (2022) A Clinical Perspective of the Multifaceted Mechanism of Metformin in Diabetes, Infections, Cognitive Dysfunction, and Cancer. Pharmaceuticals 15:4, pages 442.
Crossref
Crossref
Xing Gu, Zehao Si, Yizhen Yan & Xiangyang Zhang. (2022) Computational study of metformin hydrochloride nucleation in hydroxylic solvents: Experimental kinetics and DFT simulation. International Journal of Pharmaceutics 616, pages 121517.
Crossref
Crossref
Ming-Li Sun, Hui-Juan Liu, Xiang-Dong Luo, Yu Wang, Wei Zhang, Chen Liu & Xinghe Wang. (2022) Bioequivalence and Safety Assessment of Two Formulations of Metformin Hydrochloride Sustained-Release Tablets (Yuantang® SR and Glucophage® XR) Under Fed Conditions in Healthy Chinese Adult Subjects: An Open-Label, Two-Way Crossover, Sequence Randomized Phase I Clinical Trial. Drugs in R&D 22:1, pages 51-60.
Crossref
Crossref
Qi Yu, Xue Jiang, Xiaoyao Liu, Wenwen Shen, Xifan Mei, He Tian & Chao Wu. (2022) Glutathione-modified macrophage-derived cell membranes encapsulated metformin nanogels for the treatment of spinal cord injury. Biomaterials Advances 133, pages 112668.
Crossref
Crossref
Xiaowei Yang, Qi Lai, Xinmin Yang, Banglin Xie, Bin Zhang, Xiaoyong Zhang & Yen Wei. (2022) Recent development and advances in the fabrication and biomedical applications of nanoparticle-based drug delivery systems for metformin. Materials Chemistry Frontiers 6:2, pages 128-144.
Crossref
Crossref
KuldeepS Patil, Monica Mahajani, SnehaH Choudhary, SamiD Aldhuwayhi, Amar Thakare & MohammedZiauddeen Mustafa. (2022) Efficacy of 1.5% metformin gel as an adjuvant to scaling, root planing, and curettage for the treatment of infrabony defects in chronic periodontitis patients. Contemporary Clinical Dentistry 13:1, pages 18.
Crossref
Crossref
Akhlesh K. Jain, Richa Upadhyay, Keerti Mishra & Sunil K. Jain. (2022) Gastroretentive Metformin Loaded Nanoparticles for the Effective Management
of Type-2 Diabetes Mellitus. Current Drug Delivery 19:1, pages 93-103.
Crossref
Crossref
Sakshi Priya, Anchal Tyagi, Mahaveer Singh, Sushama Rawat, Abhay Raizaday, Santosh Kumar Singh & Gaurav Gupta. 2022. Drug Delivery Systems for Metabolic Disorders. Drug Delivery Systems for Metabolic Disorders
217
232
.
Tahira Khan, Bushra Nabi, Saleha Rehman, Mohd. Akhtar, Javed Ali & Abul Kalam Najmi. (2021)
Quality by Design Approach to Formulate Empagliflozin-Loaded Chitosan Nanoparticles:
In Vitro
,
In Vivo
and Pharmacokinetic Evaluation of Anti-Diabetic Drugs
. Nano 16:13.
Crossref
Crossref
Xiang Gao, Xinyi Cong, Yue Wang, Wenjie Zhong, Lan Huang, Xinyan Wang, Poyu Chen, Zhangmin He, Bo Hu & Jinlin Song. (2021) Fabrication of antioxidative and antibacterial surface coatings with metformin-loaded self-assembled multilayers for periodontal regeneration in diabetes mellitus patients. Journal of Materials Science 56:33, pages 18668-18683.
Crossref
Crossref
Jheel Dholakia, Bala Prabhakar & Pravin Shende. (2021) Strategies for the delivery of antidiabetic drugs via intranasal route. International Journal of Pharmaceutics 608, pages 121068.
Crossref
Crossref
Zhen Wei Marcus Tong, Emma Grant, Stephanie Gras, Melanie Wu, Corey Smith, Helen L. Barrett, Linda A. Gallo & Kirsty R. Short. (2021) The role of T‐cell immunity in COVID‐19 severity amongst people living with type II diabetes. The FEBS Journal 288:17, pages 5042-5054.
Crossref
Crossref
Eike Folker Busmann, Julia Kollan, Karsten Mäder & Henrike Lucas. (2021) Ovarian Accumulation of Nanoemulsions: Impact of Mice Age and Particle Size. International Journal of Molecular Sciences 22:15, pages 8283.
Crossref
Crossref
Noha M. Meligi, Amro K. F. Dyab & Vesselin N. Paunov. (2021) Sustained In Vitro and In Vivo Delivery of Metformin from Plant Pollen-Derived Composite Microcapsules. Pharmaceutics 13:7, pages 1048.
Crossref
Crossref
Maria V. Babak, Kai Ren Chong, Peter Rapta, Markella Zannikou, Hui Min Tang, Lisa Reichert, Meng Rui Chang, Vladimir Kushnarev, Petra Heffeter, Samuel M. Meier‐Menches, Zhi Chiaw Lim, Jian Yu Yap, Angela Casini, Irina V. Balyasnikova & Wee Han Ang. (2021) Interfering with Metabolic Profile of Triple‐Negative Breast Cancers Using Rationally Designed Metformin Prodrugs. Angewandte Chemie International Edition 60:24, pages 13405-13413.
Crossref
Crossref
Maria V. Babak, Kai Ren Chong, Peter Rapta, Markella Zannikou, Hui Min Tang, Lisa Reichert, Meng Rui Chang, Vladimir Kushnarev, Petra Heffeter, Samuel M. Meier‐Menches, Zhi Chiaw Lim, Jian Yu Yap, Angela Casini, Irina V. Balyasnikova & Wee Han Ang. (2021) Interfering with Metabolic Profile of Triple‐Negative Breast Cancers Using Rationally Designed Metformin Prodrugs. Angewandte Chemie 133:24, pages 13517-13525.
Crossref
Crossref
Sabine Szunerits, Sorin Melinte, Alexandre Barras, Quentin Pagneux, Anna Voronova, Amar Abderrahmani & Rabah Boukherroub. (2021) The impact of chemical engineering and technological advances on managing diabetes: present and future concepts. Chemical Society Reviews 50:3, pages 2102-2146.
Crossref
Crossref
Shabnam Fakhari, Azita Nouri, Mina Jamzad, Samira Arab‐Salmanabadi & Foujan Falaki. (2020)
Investigation of inclusion complex of metformin into selective cyclic peptides as novel drug delivery system: Structure, electronic properties,
AIM,
and
NBO
study via
DFT
. Journal of the Chinese Chemical Society 68:1, pages 67-75.
Crossref
Crossref
Manman Li, Qiang Shen, Wenjie Lu, Jiayi Chen, Lingfei Yu, Songlin Liu, Xiangjiang Nie, Liangyu Shao, Yulei Liu, Song Gao & Rongfeng Hu. (2020) Development and evaluation of controlled release of metformin hydrochloride for improving the oral bioavailability based on a novel enteric osmotic pump capsule. Journal of Drug Delivery Science and Technology 60, pages 102054.
Crossref
Crossref
Sara Salatin, Mitra Alami-Milani & Mitra Jelvehgari. (2020) Expert design and optimization of a novel buccoadhesive blend film impregnated with metformin nanoparticles. Therapeutic Delivery 11:9, pages 573-590.
Crossref
Crossref
Samson Mathews Samuel, Elizabeth Varghese, Lenka Koklesová, Alena Líšková, Peter Kubatka & Dietrich Büsselberg. (2020) Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells. Cancers 12:9, pages 2482.
Crossref
Crossref
Dewi Melani Hariyadi & Nazrul Islam. (2020) Current Status of Alginate in Drug Delivery. Advances in Pharmacological and Pharmaceutical Sciences 2020, pages 1-16.
Crossref
Crossref
Ahmed Gedawy, Crispin R Dass & Hani Al-Salami. (2020) Polydimethylsiloxane-customized nanoplatform for delivery of antidiabetic drugs. Therapeutic Delivery 11:7, pages 415-429.
Crossref
Crossref
Muhammad Usman Ghori, Jorabar Singh Nirwan, Taimoor Asim, Younes Chahid, Samia Farhaj, Zara Khizer, Peter Timmins & Barbara R. Conway. (2020) MUCO-DIS: a New AFM-Based Nanoscale Dissolution Technique. AAPS PharmSciTech 21:5.
Crossref
Crossref
Ganesan Arun, Rajendran Rajaram, Karunanidhi Kaleshkumar, Nambirajan Gayathri, Thilagar Sivasudha & Singaram Kandasamy. (2020) Synergistic effect of novel chitosan combined metformin drug on streptozotocin-induced diabetes mellitus rat. International Journal of Biological Macromolecules 153, pages 1335-1349.
Crossref
Crossref
Rajveer Kaur Kang, Neeraj Mishr & Vineet Kumar Rai. (2020) Guar Gum Micro-particles for Targeted Co-delivery of Doxorubicin and Metformin HCL for Improved Specificity and Efficacy Against Colon Cancer: In Vitro and In Vivo Studies. AAPS PharmSciTech 21:2.
Crossref
Crossref
Mojtaba Abbasian, Parvaneh Bighlari, Farideh Mahmoodzadeh, Metin Hayri Acar & Mehdi Jaymand. (2019)
A
de novo
formulation of metformin using chitosan‐based nanomicelles for potential diabetes therapy
. Journal of Applied Polymer Science 136:41, pages 48037.
Crossref
Crossref
Annise ProboningratAmaq FadhollyRegina Purnama Dewi IskandarAgung Budianto AchmadFedik Abdul RantamSri Agus Sudjarwo. (2019) The potency of chitosan-based Pinus merkusii bark extract nanoparticles as anti-cancer on HeLa cell lines. Veterinary World 12:10, pages 1616-1623.
Crossref
Crossref
Marc Foretz, Bruno Guigas & Benoit Viollet. (2019) Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus. Nature Reviews Endocrinology 15:10, pages 569-589.
Crossref
Crossref
T. Shams, F. Brako, S. Huo, A. H. Harker, U. Edirisinghe & M. Edirisinghe. (2019) The influence of drug solubility and sampling frequency on metformin and glibenclamide release from double-layered particles: experimental analysis and mathematical modelling. Journal of The Royal Society Interface 16:155, pages 20190237.
Crossref
Crossref
Gaurav Taneja, Akash Sud, Narayan Pendse, Bishnu Panigrahi, Ashish Kumar & Arun K. Sharma. (2018) Nano-medicine and Vascular Endothelial Dysfunction: Options and Delivery Strategies. Cardiovascular Toxicology 19:1, pages 1-12.
Crossref
Crossref
Muyun Wei, Shaowei Mao, Guoliang Lu, Liang Li, Xiaopeng Lan, Zhongxian Huang, Yougen Chen, Miaoqing Zhao, Yueran Zhao & Qinghua Xia. (2018) Valproic acid sensitizes metformin-resistant human renal cell carcinoma cells by upregulating H3 acetylation and EMT reversal. BMC Cancer 18:1.
Crossref
Crossref
Aline Pereira, Gerly Brito, Maria Lima, Arnóbio Silva Júnior, Emanuell Silva, Adriana de Rezende, Raul Bortolin, Maria Galvan, Flávia Pirih, Raimundo Araújo Júnior, Caroline Medeiros, Gerlane Guerra & Aurigena Araújo. (2018) Metformin Hydrochloride-Loaded PLGA Nanoparticle in Periodontal Disease Experimental Model Using Diabetic Rats. International Journal of Molecular Sciences 19:11, pages 3488.
Crossref
Crossref
Reza Entezari Heravi, Sajad Zakeri & Pardis Nazari. (2018) Anticancer activity evaluation of green synthesised gold–silver alloy nanoparticles on colourectal HT‐29 and prostate DU‐145 carcinoma cell lines. Micro & Nano Letters 13:10, pages 1475-1479.
Crossref
Crossref
Elisa Rampacci, Maria Luisa Marenzoni, Elisabetta Chiaradia, Fabrizio Passamonti, Maurizio Ricci, Marco Pepe, Mauro Coletti & Stefano Giovagnoli. (2018) In vitro performances of novel co-spray-dried azithromycin/rifampicin microparticles for Rhodococcus equi disease treatment. Scientific Reports 8:1.
Crossref
Crossref
Tahereh Azizi Vahed, M. Reza Naimi-Jamal & Leila Panahi. (2018) (Fe)MIL-100-Met@alginate: a hybrid polymer–MOF for enhancement of metformin's bioavailability and pH-controlled release. New Journal of Chemistry 42:13, pages 11137-11146.
Crossref
Crossref