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Artificial Cells, Blood Substitutes, and Biotechnology Volume 39, 2011 - Issue 3
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Research Article

Pharmacodynamic Study of Polymerized Porcine Hemoglobin (pPolyHb) in a Rat Model of Exchange Transfusion

Hongli Zhu College of Life Science and National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an, P. R. China
,
Xiaodong Dang Anesthesia Department, Shaanxi Cancer Hospital, Xi'an, P. R. China
,
Kunping Yan College of Life Science, Northwest University, Xi'an, P. R. China
,
Penggao Dai College of Life Science, Northwest University, Xi'an, P. R. China
,
Chao Luo Shaanxi Lifegen Co. Ltd., Xi'an, P. R. China
,
Jun Ma College of Life Science, Northwest University, Xi'an, P. R. China
,
Yan Li College of Life Science, Northwest University, Xi'an, P. R. China
,
Thomas Ming Swi Chang Artificial Cells & Organs Research Centre, Departments of Physiology, Medicine and Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
&
Chao Chen College of Life Science and National Engineering Center, Northwest University, Xi'an, P. R. China; National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an, P. R. ChinaCorrespondence[email protected]
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Pages 119-126 | Published online: 07 Mar 2011

Citations (13)

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Wenjin Zhu, Fang Liu, Li Wang, Bo Yang, Yuwei Bai, Yanzhi Huang, Yaru Li, Wei Li, Yuemin Yuan, Chao Chen & Hongli Zhu. (2019) pPolyHb protects myocardial H9C2 cells against ischemia-reperfusion injury by regulating the Pink1-Parkin-mediated mitochondrial autophagy pathway. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 1248-1255.
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Yuesheng Shen, Wenjin Zhu, Mengye Zhao, Guige Zhao, Geng Niu, Yuwei Bai, Bo Yang, Chao Chen & Hongli Zhu. (2018) Study of the pharmacokinetics of polymerized porcine hemoglobin (pPolyHb). Artificial Cells, Nanomedicine, and Biotechnology 46:7, pages 1373-1379.
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Jing Zhao, Chengbin Yan, Lijuan Xu, Kunping Yan, Bao Feng, Mengye Zhao, Geng Niu, Mengdi Wu, Chao Chen & Hongli Zhu. (2017) The effect of pPolyHb on hemodynamic stability and mesenteric microcirculation in a rat model of hemorrhagic shock. Artificial Cells, Nanomedicine, and Biotechnology 45:4, pages 677-685.
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Huifang Liu, Chengbin Yan, Kunping Yan, Wenjin Zhu, Yuesheng Shen, Bo Yang, Chao Chen & Hongli Zhu. (2017) Study of the effects of polymerized porcine hemoglobin (pPolyHb) in an acute anemia rat model. Artificial Cells, Nanomedicine, and Biotechnology 45:4, pages 694-700.
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Li Wang, Fang Liu, Kunping Yan, Wencan Pan, Lijuan Xu, Huifang Liu, Chengbin Yan, Chao Chen & Hongli Zhu. (2017) Effects of resuscitation with polymerized porcine hemoglobin (pPolyHb) on hemodynamic stability and oxygen delivery in a rat model of hemorrhagic shock. Artificial Cells, Nanomedicine, and Biotechnology 45:1, pages 51-57.
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Wenjin Zhu, Fang Liu, Jianguo Xin, Zhilan Xie, Boya Su, Chengbin Yan, Jia Zhang, Chao Chen & Hongli Zhu. (2016) Study of the inflammatory response of immunocytes to polymerized porcine hemoglobin (pPolyHb). Artificial Cells, Nanomedicine, and Biotechnology 44:2, pages 448-455.
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Zhilan Xie, Lijun Liu, Wenjin Zhu, Huifang Liu, Li Wang, Jia Zhang, Chao Chen & Hongli Zhu. (2015) The protective effect of polymerized porcine hemoglobin (pPolyHb) on transient focal cerebral ischemia/reperfusion injury. Artificial Cells, Nanomedicine, and Biotechnology 43:3, pages 180-185.
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Haiyan Xue, Kunping Yan, Xiufang Zhao, Wenjin Zhu, Lijun Liu, Zhilan Xie, Hongli Zhu & Chao Chen. (2015) Pretreatment with pPolyHb attenuates H2O2-induced endothelial cell injury through inhibition of JNK/p38 MAPK pathway by upregulation of heme oxygenase-1. Artificial Cells, Nanomedicine, and Biotechnology 43:3, pages 163-173.
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He Huang, Jun Ma, Wenjin Zhu, Jinghui Sun, Kunping Yan, Bo Song, Yuejin Xue, Jianguo Xin, Wencan Pan, Hongli Zhu & Chao Chen. (2014) The application of polymerized porcine hemoglobin (pPolyHb) in the rat small bowel preservation. Artificial Cells, Nanomedicine, and Biotechnology 42:5, pages 289-295.
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Hongli Zhu, Kunping Yan, Xiaodong Dang, He Huang, Erfang Chen, Bang Chen, Chao Luo, Thomas Ming Swi Chang, Penggao Dai & Chao Chen. (2011) Immune Safety Evaluation of Polymerized Porcine Hemoglobin (pPolyHb): A Potential Red Blood Cell Substitute. Artificial Cells, Blood Substitutes, and Biotechnology 39:6, pages 398-405.
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Articles from other publishers (3)

Bin Li, Jie Zhang, Chuanyan Shen, Tingting Zong, Cong Zhao, Yumin Zhao, Yunhua Lu, Siyue Sun & Hongli Zhu. (2022) Application of polymerized porcine hemoglobin in the ex vivo normothermic machine perfusion of rat livers. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Nitin B. Charbe, Francisco Castillo, Murtaza M. Tambuwala, Parteek Prasher, Dinesh Kumar Chellappan, Aurora Carreño, Saurabh Satija, Sachin Kumar Singh, Monica Gulati, Kamal Dua, José Vicente González-Aramundiz & Flavia C. Zacconi. (2022) A new era in oxygen therapeutics? From perfluorocarbon systems to haemoglobin-based oxygen carriers. Blood Reviews 54, pages 100927.
Crossref
Thomas Ming Swi Chang. 2014. Principles of Tissue Engineering. Principles of Tissue Engineering 1059 1073 .

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