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Original Article

Reaction of Human Endothelial Cells to Bovine Hemoglobin Solutions and Tumor Necrosis Factor

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Pages 777-787 | Published online: 11 Jul 2009

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Read on this site (5)

Jan Simoni, Grace Simoni, John F. Moeller, James P. Tsikouris & Donald E. Wesson. (2007) Evaluation of Angiotensin Converting Enzyme (ACE)-Like Activity of Acellular Hemoglobin. Artificial Cells, Blood Substitutes, and Biotechnology 35:2, pages 191-210.
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Ann L. Baldwin & Elizabeth B. Wiley. (2002) SELENIUM REDUCES HEMOGLOBIN-INDUCED EPITHELIAL DAMAGE TO INTESTINAL MUCOSA. Artificial Cells, Blood Substitutes, and Biotechnology 30:1, pages 1-22.
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Jan Simoni, Grace Simoni, Shelley Weinstock, Charles Lox & Mario Feola. (1998) An improved blood substitute. Emerging Therapeutic Targets 2:1, pages 85-91.
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Jan Simoni, Grace Simoni, Charles D. Lox, Samuel D. Prien, Rue Tran & Tom Shires. (1997) Expression of Adhesion Molecules and von Willebrand Factor in Human Coronary Artery Endothelial Cells Incubated with Differently Modified Hemoglobin Solutions. Artificial Cells, Blood Substitutes, and Biotechnology 25:1-2, pages 211-225.
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Jan Simoni, Grace Simoni, Charles D. Lox, Samuel D. Prien & G. Tom Shires. (1997) Modified Hemoglobin Solution, with Desired Pharmacological Properties, Does not Activate Nuclear Transcription Factor NF-kappa B in Human Vascular Endothelial Cells. Artificial Cells, Blood Substitutes, and Biotechnology 25:1-2, pages 193-210.
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Articles from other publishers (21)

Onur ELMAS & Sinem ELMAS. (2020) Eritrositlerde Oksidatif Stres Oluşumunda Rol Oynayan Özgül Mekanizmalar ve Koruyucu Antioksidan SistemlerSpecific Mechanisms and Protective Antioxidant Systems Playing Role in Occurring Oxidative Stress in Erythrocytes. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 7:3, pages 170-179.
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Wei Zhang, Kunping Yan, Penggao Dai, Jingjing Tian, Hongli Zhu & Chao Chen. (2011) A Novel Hemoglobin‐Based Oxygen Carrier, Polymerized Porcine Hemoglobin, Inhibits H 2 O 2 ‐Induced Cytotoxicity of Endothelial Cells . Artificial Organs 36:2, pages 151-160.
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Jan Simoni, Javier Villanueva-Meyer, Grace Simoni, John F. Moeller & Donald E. Wesson. (2009) Control of Oxidative Reactions of Hemoglobin in the Design of Blood Substitutes: Role of the Ascorbate-Glutathione Antioxidant System. Artificial Organs 33:2, pages 115-126.
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Jan Simoni, Grace Simoni & John F. Moeller. (2009) Intrinsic Toxicity of Hemoglobin: How to Counteract It. Artificial Organs 33:2, pages 100-109.
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Caroline GaucherPatrick Menu. (2008) How to Evaluate Blood Substitutes for Endothelial Cell Toxicity. Antioxidants & Redox Signaling 10:7, pages 1153-1162.
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Simona A. Dragan, Kenneth W. Olsen, Edwin G. Moore & Alanah Fitch. (2008) Spectroelectrochemical study of hemoglobin A, alpha- and beta-fumarate crosslinked hemoglobins; implications to autoxidation reaction. Bioelectrochemistry 73:1, pages 55-63.
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Jan Simoni, Grace Simoni, John A. Griswold, John F. Moeller, James P. Tsikouris, Apurv Khanna, Chanwit Roongsritong & Donald E. Wesson. (2006) Role of Free Hemoglobin in 8-Iso Prostaglandin F2-Alpha Synthesis in Chronic Renal Failure and Its Impact on CD163-Hb Scavenger Receptor and on Coronary Artery Endothelium. ASAIO Journal 52:6, pages 652-661.
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Jun Mohara, Irene Aguilera, Bruce I. Goldman, Carol A. Fisher, John P. Gaughan, Joseph R. Libonati, Satoshi Furukawa & Arun K. Singhal. (2005) Effects of Nutrient and Hemoglobin Enriched Cell Free Perfusates Upon Ex Vivo Isolated Rat Heart Preparation. ASAIO Journal 51:3, pages 288-295.
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Jan Simoni. 2005. Artificial Oxygen Carrier. Artificial Oxygen Carrier 75 126 .
Ann L. Baldwin. (2004) Blood Substitutes and Redox Responses in the Microcirculation. Antioxidants & Redox Signaling 6:6, pages 1019-1030.
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H. Northoff & C. Weinstock. 2004. Transfusionsmedizin. Transfusionsmedizin 565 575 .
Ann L. BaldwinElizabeth B. WileyAmber G. Summers & Abdu I. Alayash. (2003) Sodium selenite reduces hemoglobin-induced venular leakage in the rat mesentery. American Journal of Physiology-Heart and Circulatory Physiology 284:1, pages H81-H91.
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Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
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Jan Simoni, Grace Simoni, Donald E. Wesson, John A. Griswold & Mario Feola. (2000) A Novel Hemoglobin-Adenosine-Glutathione Based Blood Substitute: Evaluation of Its Effects on Human Blood Ex Vivo. ASAIO Journal 46:6, pages 679-692.
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Felice D’Agnillo & Abdu I. Alayash. (2000) Site-specific modifications and toxicity of blood substitutes. Advanced Drug Delivery Reviews 40:3, pages 199-212.
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Daniel W. Goldman, Richard J. BreyerIIIIII, David Yeh, Beth A. Brockner-Ryan & Abdu I. Alayash. (1998) Acellular hemoglobin-mediated oxidative stress toward endothelium: a role for ferryl iron. American Journal of Physiology-Heart and Circulatory Physiology 275:3, pages H1046-H1053.
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A.I. Alayash. 1998. Blood Substitutes, Present and Future Perspectives. Blood Substitutes, Present and Future Perspectives 201 210 .
Nikolai V. Gorbunov, Jack C. Yalowich, Arunasri Gaddam, Padmakumari Thampatty, Vladimir B. Ritov, Elena R. Kisin, Nabil M. Elsayed & Valerian E. Kagan. (1997) Nitric Oxide Prevents Oxidative Damage Produced bytert-Butyl Hydroperoxide in Erythroleukemia Cells via Nitrosylation of Heme and Non-heme Iron. Journal of Biological Chemistry 272:19, pages 12328-12341.
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Wim Bleeker, Jacques Agterberg, Erik La Hey, Gemma Rigter, Lily Zappeij & Joa Bakker. 1996. Blood Substitutes. Blood Substitutes 112 123 .
Jan Simoni, Grace Simoni, Charles D. Lox, Samuel D. Prien & G.Tom Shires. (1995) Hemoglobin interference with an enzyme-linked immunosorbent assay for the detection of tumor necrosis factor-alpha. Analytica Chimica Acta 313:1-2, pages 1-14.
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Abdu I. Alayash & Robert E. Cashon. (1995) Hemoglobin and free radicals: implications for the development of a safe blood substitute. Molecular Medicine Today 1:3, pages 122-127.
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