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Artificial Cells, Blood Substitutes, and Biotechnology Volume 22, 1994 - Issue 4
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Original Article

Pharmacokinetics and Side Effects of Perfluorocarbon-Based Blood Substitutes

Stephen F. Flaim Alliance Pharmaceutical Corp., San Diego, CA, 92121
Pages 1043-1054 | Published online: 11 Jul 2009

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Ryan Holman, Laura Gui, Orane Lorton, Pauline Guillemin, Stéphane Desgranges, Christiane Contino-Pépin & Rares Salomir. (2022) PFOB sonosensitive microdroplets: determining their interaction radii with focused ultrasound using MR thermometry and a Gaussian convolution kernel computation. International Journal of Hyperthermia 39:1, pages 108-119.
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Charalambos Tsagogiorgas, Friedrich Anger, Grietje Beck, Annette Breedijk, Benito Yard & Simone Hoeger. (2019) Impact of different emulsifiers on biocompatibility and inflammatory potential of Perfluorohexyloctane (F6H8) emulsions for new intravenous drug delivery systems. Drug Design, Development and Therapy 13, pages 2097-2110.
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Anna Wrobeln, Klaus D. Schlüter, Jürgen Linders, Manfred Zähres, Christian Mayer, Michael Kirsch & Katja B. Ferenz. (2017) Functionality of albumin-derived perfluorocarbon-based artificial oxygen carriers in the Langendorff-heart . Artificial Cells, Nanomedicine, and Biotechnology 45:4, pages 723-730.
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Jennifer L.H. Johnson, Melissa C. Dolezal, Arthur Kerschen, Terry O. Matsunaga & Evan C. Unger. (2009) In Vitro Comparison of Dodecafluoropentane (DDFP), Perfluorodecalin (PFD), and Perfluoroctylbromide (PFOB) in the Facilitation of Oxygen Exchange. Artificial Cells, Blood Substitutes, and Biotechnology 37:4, pages 156-162.
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Hans-Joachim Lehmler. (2007) Perfluorocarbon compounds as vehicles for pulmonary drug delivery. Expert Opinion on Drug Delivery 4:3, pages 247-262.
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Patrick M Winter, Kejia Cai, Shelton D Caruthers, Samuel A Wickline & Gregory M Lanza. (2007) Emerging nanomedicine opportunities with perfluorocarbon nanoparticles. Expert Review of Medical Devices 4:2, pages 137-145.
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Anne M. Neubauer, Shelton D. Caruthers, Franklin D. Hockett, Tillman Cyrus, J. David Robertson, J. Stacy Allen, Todd D. Williams, Ralph W. Fuhrhop, Gregory M. Lanza & Samuel A. Wickline. (2007) Fluorine Cardiovascular Magnetic Resonance Angiography In Vivo at 1.5 T with Perfluorocarbon Nanoparticle Contrast Agents. Journal of Cardiovascular Magnetic Resonance 9:3, pages 565-573.
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Ching‐An Peng, Jie Da, Yu‐Chih Hsu & Thieo E. Hogen‐Esch. (2006) Polymeric Fluorosurfactant‐Mediated Perfluorocarbon Emulsions. Journal of Dispersion Science and Technology 27:3, pages 377-387.
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Ching-An Peng & Yu-Chih Hsu. (2001) FLUOROALKYLATED POLYETHYLENE GLYCOL AS POTENTIAL SURFACTANT FOR PERFLUOROCARBON EMULSION. Artificial Cells, Blood Substitutes, and Biotechnology 29:6, pages 483-492.
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David M. Eckmann, Melody A. Swartz, Matthew R. Glucksberg, Noam Gavriely & James B. Grotberg. (1998) Perfluorocarbon Induced Alterations in Pulmonary Mechanics. Artificial Cells, Blood Substitutes, and Biotechnology 26:3, pages 259-271.
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Thomas F. Zuck, Jean G. Riess & G. P. Biro. (1994) Current Status of Injectable Oxygen Carriers. Critical Reviews in Clinical Laboratory Sciences 31:4, pages 295-324.
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Peter E. Keipert. 2022. Blood Substitutes and Oxygen Biotherapeutics. Blood Substitutes and Oxygen Biotherapeutics 325 334 .
Brooke M. Helfer, Vladimir Ponomarev, P. Stephen Patrick, Philip J. Blower, Alexandra Feitel, Gilbert O. Fruhwirth, Shawna Jackman, Lucilia Pereira Mouriès, Margriet V.D.Z. Park, Mangala Srinivas, Daniel J. Stuckey, Mya S. Thu, Tineke van den Hoorn, Carla A. Herberts & William D. Shingleton. (2021) Options for imaging cellular therapeutics in vivo: a multi-stakeholder perspective. Cytotherapy 23:9, pages 757-773.
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DIRK MAYER, FRANÇOIS GUERRERO, CHRISTELLE GOANVEC, LISA HETZEL, JÜRGEN LINDERS, MARKO LJUBKOVIC, ALFONS KRECZY, CHRISTIAN MAYER, MICHAEL KIRSCH & KATJA BETTINA FERENZ. (2020) Prevention of Decompression Sickness by Novel Artificial Oxygen Carriers. Medicine & Science in Sports & Exercise 52:10, pages 2127-2135.
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Tamilvanan ShunmugaperumalOly Katari, Tamilvanan Shunmugaperumal, Datta Maroti Pawde & Abhinab Goswami. 2020. Oil‐in‐Water Nanosized Emulsions for Drug Delivery and Targeting. Oil‐in‐Water Nanosized Emulsions for Drug Delivery and Targeting 287 368 .
Sam Peppou-Chapman, Jun Ki Hong, Anna Waterhouse & Chiara Neto. (2020) Life and death of liquid-infused surfaces: a review on the choice, analysis and fate of the infused liquid layer. Chemical Society Reviews 49:11, pages 3688-3715.
Crossref
Carlos J. Brambila, Jacques Lux, Robert F. Mattrey, Dustin Boyd, Mark A. Borden & Caroline de Gracia Lux. (2020) Bubble Inflation Using Phase-Change Perfluorocarbon Nanodroplets as a Strategy for Enhanced Ultrasound Imaging and Therapy. Langmuir 36:11, pages 2954-2965.
Crossref
W. Krämer, R. Schubert & U. Massing. (2019) Small-scale preparation of perfluorocarbon-nanoemulsions utilizing dual centrifugation. International Journal of Pharmaceutics 572, pages 118753.
Crossref
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Crossref
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Crossref
W. Krämer, C. Grapentin, P. Bouvain, S. Temme, U. Flögel & R. Schubert. (2019) Rational manufacturing of functionalized, long-term stable perfluorocarbon-nanoemulsions for site-specific 19F magnetic resonance imaging. European Journal of Pharmaceutics and Biopharmaceutics 142, pages 114-122.
Crossref
Donald A. Fernandes & Michael C. Kolios. (2019) Near-infrared absorbing nanoemulsions as nonlinear ultrasound contrast agents for cancer theranostics. Journal of Molecular Liquids 287, pages 110848.
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Qin Zhou, Yalin Zeng, Qingsong Xiong, Shigen Zhong, Pan Li, Haitao Ran, Yuehui Yin, Chris Reutelingsperger, Frits W. Prinze & Zhiyu Ling. (2019) Construction of CNA35 Collagen-Targeted Phase-Changeable Nanoagents for Low-Intensity Focused Ultrasound-Triggered Ultrasound Molecular Imaging of Myocardial Fibrosis in Rabbits. ACS Applied Materials & Interfaces 11:26, pages 23006-23017.
Crossref
Dmitry Nevozhay, Michael Weiger, Peter Friedl & Konstantin V. Sokolov. (2019) Spatiotemporally controlled nano-sized third harmonic generation agents. Biomedical Optics Express 10:7, pages 3301.
Crossref
Paulo N. Martins, Timothy A. Berendsen, Heidi Yeh, Bote G. Bruinsma, Maria-Louisa Izamis, Sanna Op den Dries, Andrew R. Gillooly, Robert Porte, Martin L. Yarmush, Korkut Uygun & James F. Markmann. (2019) Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts. Transplantation 103:2, pages 363-370.
Crossref
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Crossref
Amin Haghighat Jahromi, Chao Wang, Stephen R. Adams, Wenlian Zhu, Kazim Narsinh, Hongyan Xu, Danielle L. Gray, Roger Y. Tsien & Eric T. Ahrens. (2018) Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes. ACS Nano 13:1, pages 143-151.
Crossref
Da Shi, Su Xu, Jiachen Zhuo, Mary C. McKenna & Rao P. Gullapalli. (2019) White Matter Alterations in <b><i>Fmr1</i></b> Knockout Mice during Early Postnatal Brain Development. Developmental Neuroscience 41:5-6, pages 274-289.
Crossref
Raghuram Chava & Harikrishna Tandri. 2019. Therapeutic Intranasal Delivery for Stroke and Neurological Disorders. Therapeutic Intranasal Delivery for Stroke and Neurological Disorders 1 7 .
Margeaux A. Miller & Ellen M. Sletten. (2018) A General Approach to Biocompatible Branched Fluorous Tags for Increased Solubility in Perfluorocarbon Solvents. Organic Letters 20:21, pages 6850-6854.
Crossref
Aman Khurana, Fanny Chapelin, Hongyan Xu, Joseph R. Acevedo, Alfred Molinolo, Quyen Nguyen & Eric T. Ahrens. (2017) Visualization of macrophage recruitment in head and neck carcinoma model using fluorine‐19 magnetic resonance imaging. Magnetic Resonance in Medicine 79:4, pages 1972-1980.
Crossref
Koen D. Reesink, Tim Hendrikx, Patrick J. van Gorp, Arnold P. Hoeks & Ronit Shiri-Sverdlov. (2018) Ultrasonic Perfluorohexane-Loaded Monocyte Imaging: Toward a Minimally Invasive Technique for Selective Detection of Liver Inflammation in Fatty Liver Disease. Journal of Ultrasound in Medicine 37:4, pages 921-933.
Crossref
Huaifa Zhang & Jake E. Barralet. (2017) Mimicking oxygen delivery and waste removal functions of blood. Advanced Drug Delivery Reviews 122, pages 84-104.
Crossref
Sridhar Akula, Ivy K. Brosch & Nic D. Leipzig. (2017) Fluorinated Methacrylamide Chitosan Hydrogels Enhance Cellular Wound Healing Processes. Annals of Biomedical Engineering 45:11, pages 2693-2702.
Crossref
Anna Wrobeln, Julia Laudien, Christoph Groß-Heitfeld, Jürgen Linders, Christian Mayer, Benjamin Wilde, Tanja Knoll, Dominik Naglav, Michael Kirsch & Katja B. Ferenz. (2017) Albumin-derived perfluorocarbon-based artificial oxygen carriers: A physico-chemical characterization and first in vivo evaluation of biocompatibility. European Journal of Pharmaceutics and Biopharmaceutics 115, pages 52-64.
Crossref
Christine Arthur, Lin Song, William Culp, Aliza Brown, Michael Borrelli, Robert Skinner & Howard Hendrickson. (2016) Tissue Concentration of Dodecafluoropentane (DDFP) Following Repeated IV Administration in the New Zealand White Rabbit. The AAPS Journal 19:2, pages 520-526.
Crossref
Changkui Fu, Shauna Herbst, Cheng Zhang & Andrew K. Whittaker. (2017) Polymeric 19 F MRI agents responsive to reactive oxygen species . Polymer Chemistry 8:31, pages 4585-4595.
Crossref
Jennifer L. H. Johnson. 2017. Neuroprotective Therapy for Stroke and Ischemic Disease. Neuroprotective Therapy for Stroke and Ischemic Disease 621 640 .
Edyta Swider & Mangala Srinivas. 2017. Design and Applications of Nanoparticles in Biomedical Imaging. Design and Applications of Nanoparticles in Biomedical Imaging 153 170 .
Lara Gazzera, Roberto Milani, Lisa Pirrie, Marc Schmutz, Christian Blanck, Giuseppe Resnati, Pierangelo Metrangolo & Marie Pierre Krafft. (2016) Design of Highly Stable Echogenic Microbubbles through Controlled Assembly of Their Hydrophobin Shell. Angewandte Chemie International Edition 55:35, pages 10263-10267.
Crossref
Lara Gazzera, Roberto Milani, Lisa Pirrie, Marc Schmutz, Christian Blanck, Giuseppe Resnati, Pierangelo Metrangolo & Marie Pierre Krafft. (2016) Design of Highly Stable Echogenic Microbubbles through Controlled Assembly of Their Hydrophobin Shell. Angewandte Chemie 128:35, pages 10419-10423.
Crossref
Zijian Zhou, Jibin Song, Liming Nie & Xiaoyuan Chen. (2016) Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy. Chemical Society Reviews 45:23, pages 6597-6626.
Crossref
Hieu Vu-Quang, Mads Sloth Vinding, Dan Xia, Thomas Nielsen, Marcus Görge Ullisch, MingDong Dong, Niels Chr. Nielsen & Jørgen Kjems. (2016) Chitosan-coated poly(lactic-co-glycolic acid) perfluorooctyl bromide nanoparticles for cell labeling in 19F magnetic resonance imaging. Carbohydrate Polymers 136, pages 936-944.
Crossref
Anne H. Schmieder, Shelton D. Caruthers, Jochen Keupp, Samuel A. Wickline & Gregory M. Lanza. (2015) Recent Advances in 19 Fluorine Magnetic Resonance Imaging with Perfluorocarbon Emulsions. Engineering 1:4, pages 475-489.
Crossref
Jia Zhong, Kazim Narsinh, Penelope A. Morel, Hongyan Xu & Eric T. Ahrens. (2015) In Vivo Quantification of Inflammation in Experimental Autoimmune Encephalomyelitis Rats Using Fluorine-19 Magnetic Resonance Imaging Reveals Immune Cell Recruitment outside the Nervous System. PLOS ONE 10:10, pages e0140238.
Crossref
Lucia E. Duinhouwer, Bernard J. M. van Rossum, Sandra T. van Tiel, Ramon M. van der Werf, Gabriela N. Doeswijk, Joost C. Haeck, Elwin W. J. C. Rombouts, Mariëtte N. D. ter Borg, Gyula Kotek, Eric Braakman, Jan J. Cornelissen & Monique R. Bernsen. (2015) Magnetic Resonance Detection of CD34+ Cells from Umbilical Cord Blood Using a 19F Label. PLOS ONE 10:9, pages e0138572.
Crossref
F. Bönner, M.W. Merx, K. Klingel, P. Begovatz, U. Flögel, M. Sager, S. Temme, C. Jacoby, M. Salehi Ravesh, C. Grapentin, R. Schubert, J. Bunke, M. Roden, M. Kelm & J. Schrader. (2015) Monocyte imaging after myocardial infarction with 19F MRI at 3 T: a pilot study in explanted porcine hearts. European Heart Journal - Cardiovascular Imaging 16:6, pages 612-620.
Crossref
Charalambos Tsagogiorgas, Sonja Theisinger, Elisabeth Heesch, Jörg Krebs, René Holm, Grietje Beck & Benito Yard. (2015) Evaluation of pharmacokinetic properties and anaesthetic effects of propofol in a new perfluorohexyloctane (F6H8) emulsion in rats – A comparative study. International Journal of Pharmaceutics 486:1-2, pages 69-76.
Crossref
Dominik K. Kölmel, Martin Nieger & Stefan Bräse. (2015) Highly efficient synthesis of polyfluorinated dendrons suitable for click chemistry. RSC Advances 5:46, pages 36762-36765.
Crossref
Mourad Chenoune, Ludovic De Rochefort, Patrick Bruneval, Fanny Lidouren, Matthias Kohlhauer, Aurélien Seemann, Bijan Ghaleh, Matthias Korn, Rose-Marie Dubuisson, Anis Ben Yahmed, Xavier Maître, Daniel Isabey, Jean-Damien Ricard, Richard E Kerber, Luc Darrasse, Alain Berdeaux & Renaud Tissier. (2014) Evaluation of lung recovery after static administration of three different perfluorocarbons in pigs. BMC Pharmacology and Toxicology 15:1.
Crossref
Lilia V Ileva, Marcelino Bernardo, Matthew R Young, Lisa A Riffle, James L Tatum, Joseph D Kalen & Peter L Choyke. (2014) In vivo MRI virtual colonography in a mouse model of colon cancer. Nature Protocols 9:11, pages 2682-2692.
Crossref
Matthew M. Kumar, Andrew D. Goldberg, Markos Kashiouris, Lawrence R. Keenan, Alejandro A. Rabinstein, Bekele Afessa, Larry D. Johnson, John L.D. Atkinson & Vedha Nayagam. (2014) Transpulmonary hypothermia: A novel method of rapid brain cooling through augmented heat extraction from the lungs. Resuscitation 85:10, pages 1405-1410.
Crossref
Jacob Wheatley Myerson, Li He, John Stacy Allen, Todd Williams, Gregory Lanza, Douglas Tollefsen, Shelton Caruthers & Samuel Wickline. (2014) Thrombin-inhibiting nanoparticles rapidly constitute versatile and detectable anticlotting surfaces. Nanotechnology 25:39, pages 395101.
Crossref
Hang Li, Asanka Wijekoon & Nic D. Leipzig. (2013) Encapsulated Neural Stem Cell Neuronal Differentiation in Fluorinated Methacrylamide Chitosan Hydrogels. Annals of Biomedical Engineering 42:7, pages 1456-1469.
Crossref
Kristin P. Bibee, Ya‐Jian Cheng, James K. Ching, Jon N. Marsh, Allison J. Li, Richard M. Keeling, Anne M. Connolly, Paul T. Golumbek, Jacob W. Myerson, Grace Hu, Junjie Chen, William D. Shannon, Gregory M. Lanza, Conrad C. Weihl & Samuel A. Wickline. (2014) Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function. The FASEB Journal 28:5, pages 2047-2061.
Crossref
Christoph Jacoby, Sebastian Temme, Friederike Mayenfels, Nicole Benoit, Marie Pierre Krafft, Rolf Schubert, Jürgen Schrader & Ulrich Flögel. (2014) Probing different perfluorocarbons for in vivo inflammation imaging by 19 F MRI: image reconstruction, biological half-lives and sensitivity . NMR in Biomedicine 27:3, pages 261-271.
Crossref
Ali Gordji-Nejad, Klaus Möllenhoff, Ana Maria Oros-Peusquens, Deepu R. Pillai & Nadim Jon Shah. (2013) Characterizing cerebral oxygen metabolism employing oxygen-17 MRI/MRS at high fields. Magnetic Resonance Materials in Physics, Biology and Medicine 27:1, pages 81-93.
Crossref
Patrick M. Winter. (2014) Perfluorocarbon Nanoparticles: Evolution of a Multimodality and Multifunctional Imaging Agent. Scientifica 2014, pages 1-10.
Crossref
Vasiliy S. Chernyshev & Mikhail Skliar. (2014) Surface tension of water in the presence of perfluorocarbon vapors. Soft Matter 10:12, pages 1937.
Crossref
Katja B. Ferenz, Indra N. Waack, Julia Laudien, Christian Mayer, Martina Broecker-Preuss, Herbert de Groot & Michael Kirsch. (2014) Safety of poly (ethylene glycol)-coated perfluorodecalin-filled poly (lactide-co-glycolide) microcapsules following intravenous administration of high amounts in rats. Results in Pharma Sciences 4, pages 8-18.
Crossref
Sarah Decato & Sandro Mecozzi. 2014. Colloid and Interface Science in Pharmaceutical Research and Development. Colloid and Interface Science in Pharmaceutical Research and Development 319 345 .
Thomas Randsøe & O. Hyldegaard. (2013) Treatment of micro air bubbles in rat adipose tissue at 25 kPa altitude exposures with perfluorocarbon emulsions and nitric oxide. European Journal of Applied Physiology 114:1, pages 135-146.
Crossref
S. Martinho, J.M.M. Araújo, L.P.N. Rebelo, A.B. Pereiro & I.M. Marrucho. (2013) (Liquid+liquid) equilibria of perfluorocarbons with fluorinated ionic liquids. The Journal of Chemical Thermodynamics 64, pages 71-79.
Crossref
David E. Sosnovik & Peter Caravan. (2012) Molecular MRI of the Cardiovascular System in the Post-NSF Era. Current Cardiovascular Imaging Reports 6:1, pages 61-68.
Crossref
Mangala Srinivas, Philipp Boehm-Sturm, Carl G. Figdor, I. Jolanda de Vries & Mathias Hoehn. (2012) Labeling cells for in vivo tracking using 19F MRI. Biomaterials 33:34, pages 8830-8840.
Crossref
Sebastian Temme, Florian Bönner, Jürgen Schrader & Ulrich Flögel. (2012) 19 F magnetic resonance imaging of endogenous macrophages in inflammation . Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 4:3, pages 329-343.
Crossref
Csongor Szíjjártó, Simona Rossi, Gilles Waton & Marie Pierre Krafft. (2012) Effects of Perfluorocarbon Gases on the Size and Stability Characteristics of Phospholipid-Coated Microbubbles: Osmotic Effect versus Interfacial Film Stabilization. Langmuir 28:2, pages 1182-1189.
Crossref
Alexandre Moquin & Françoise M. Winnik. 2012. Field-Flow Fractionation in Biopolymer Analysis. Field-Flow Fractionation in Biopolymer Analysis 187 206 .
Huiying Zhang, Lei Zhang, Jacob Myerson, Kristin Bibee, Michael Scott, John Allen, Gregorio Sicard, Gregory Lanza & Samuel Wickline. (2011) Quantifying the Evolution of Vascular Barrier Disruption in Advanced Atherosclerosis with Semipermeant Nanoparticle Contrast Agents. PLoS ONE 6:10, pages e26385.
Crossref
Man Zhang, Mario L. Fabiilli, Kevin J. Haworth, Frederic Padilla, Scott D. Swanson, Oliver D. Kripfgans, Paul L. Carson & Jeffrey Brian Fowlkes. (2011) Acoustic Droplet Vaporization for Enhancement of Thermal Ablation by High Intensity Focused Ultrasound. Academic Radiology 18:9, pages 1123-1132.
Crossref
Tobias Hahn, Sebastian Kozerke, Werner Schwizer, Michael Fried, Peter Boesiger & Andreas Steingoetter. (2011) Visualization and quantification of intestinal transit and motor function by real-time tracking of 19 F labeled capsules in humans . Magnetic Resonance in Medicine 66:3, pages 812-820.
Crossref
Lingzhi Hu, Lei Zhang, Junjie Chen, Gregory M. Lanza & Samuel A. Wickline. (2011) Diffusional mechanisms augment the fluorine MR relaxation in paramagnetic perfluorocarbon nanoparticles that provides a “relaxation switch” for detecting cellular endosomal activation. Journal of Magnetic Resonance Imaging 34:3, pages 653-661.
Crossref
J. MYERSON, L. HE, G. LANZA, D. TOLLEFSEN & S. WICKLINE. (2011) Thrombin‐inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis. Journal of Thrombosis and Haemostasis 9:7, pages 1292-1300.
Crossref
Hua Pan, Neelesh R. Soman, Paul H. Schlesinger, Gregory M. Lanza & Samuel A. Wickline. (2011) Cytolytic peptide nanoparticles (‘NanoBees’) for cancer therapy. WIREs Nanomedicine and Nanobiotechnology 3:3, pages 318-327.
Crossref
Jesús Ruiz-Cabello, Brad P. Barnett, Paul A. Bottomley & Jeff W.M. Bulte. (2011) Fluorine (19F) MRS and MRI in biomedicine. NMR in Biomedicine 24:2, pages 114-129.
Crossref
M. Zhang, M.L. Fabiilli, K.J. Haworth, J.B. Fowlkes, O.D. Kripfgans, W.W. Roberts, K.A. Ives & P.L. Carson. (2010) Initial Investigation of Acoustic Droplet Vaporization for Occlusion in Canine Kidney. Ultrasound in Medicine & Biology 36:10, pages 1691-1703.
Crossref
C. Tsagogiorgas, J. Krebs, M. Pukelsheim, G. Beck, B. Yard, B. Theisinger, M. Quintel & T. Luecke. (2010) Semifluorinated alkanes – A new class of excipients suitable for pulmonary drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 76:1, pages 75-82.
Crossref
Mangala Srinivas, Luis J. Cruz, Fernando Bonetto, Arend Heerschap, Carl G. Figdor & I. Jolanda M. de Vries. (2010) Customizable, multi-functional fluorocarbon nanoparticles for quantitative in vivo imaging using 19F MRI and optical imaging. Biomaterials 31:27, pages 7070-7077.
Crossref
Mangala Srinivas, Arend Heerschap, Eric T. Ahrens, Carl G. Figdor & I. Jolanda M. de Vries. (2010) 19F MRI for quantitative in vivo cell tracking. Trends in Biotechnology 28:7, pages 363-370.
Crossref
Simona Rossi, Gilles Waton & Marie Pierre Krafft. (2009) Phospholipid-Coated Gas Bubble Engineering: Key Parameters for Size and Stability Control, as Determined by an Acoustical Method. Langmuir 26:3, pages 1649-1655.
Crossref
Liselotte M. Kornmann, Koen D. Reesink, Robert S. Reneman & Arnold P.G. Hoeks. (2010) Critical Appraisal of Targeted Ultrasound Contrast Agents for Molecular Imaging in Large Arteries. Ultrasound in Medicine & Biology 36:2, pages 181-191.
Crossref
Donald J. AbrahamStefano Bruno, Luca Ronda, Serena Faggiano, Stefano Bettati & Andrea Mozzarelli. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 609 660 .
Megan M. Kaneda, Shelton Caruthers, Gregory M. Lanza & Samuel A. Wickline. (2009) Perfluorocarbon Nanoemulsions for Quantitative Molecular Imaging and Targeted Therapeutics. Annals of Biomedical Engineering 37:10, pages 1922-1933.
Crossref
Neelesh R. Soman, Steven L. Baldwin, Grace Hu, Jon N. Marsh, Gregory M. Lanza, John E. Heuser, Jeffrey M. Arbeit, Samuel A. Wickline & Paul H. Schlesinger. (2009) Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth. Journal of Clinical Investigation 119:9, pages 2830-2842.
Crossref
Shelton D. CaruthersTillmann CyrusPatrick M. WinterSamuel A. WicklineGregory M. Lanza. (2009) Anti‐angiogenic perfluorocarbon nanoparticles for diagnosis and treatment of atherosclerosis. WIREs Nanomedicine and Nanobiotechnology 1:3, pages 311-323.
Crossref
Anne M. Neubauer, Hoon Sim, Patrick M. Winter, Shelton D. Caruthers, Todd A. Williams, J. David Robertson, David Sept, Gregory M. Lanza & Samuel A. Wickline. (2008) Nanoparticle pharmacokinetic profiling in vivo using magnetic resonance imaging. Magnetic Resonance in Medicine 60:6, pages 1353-1361.
Crossref
Anne M. Neubauer, Jacob Myerson, Shelton D. Caruthers, Franklin D. Hockett, Patrick M. Winter, Junjie Chen, Patrick J. Gaffney, J. David Robertson, Gregory M. Lanza & Samuel A. Wickline. (2008) Gadolinium‐modulated 19 F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging . Magnetic Resonance in Medicine 60:5, pages 1066-1072.
Crossref
Liselotte M. Kornmann, Daniëlle M. J. Curfs, Evelien Hermeling, Ingeborg van der Made, Menno P. J. de Winther, Robert S. Reneman, Koen D. Reesink & Arnold P. G. Hoeks. (2008) Perfluorohexane-loaded Macrophages as a Novel Ultrasound Contrast Agent: A Feasibility Study. Molecular Imaging and Biology 10:5, pages 264-270.
Crossref
Fellery de Lange, Kenji Yoshitani, Alan D. Proia, G Burkhard Mackensen & Hilary P. Grocott. (2008) Perfluorocarbon Administration During Cardiopulmonary Bypass in Rats: An Inflammatory Link to Adverse Outcome?. Anesthesia & Analgesia 106:1, pages 24-31.
Crossref
Patrick M. Winter, Shelton D. Caruthers, Anne H. Schmieder, Anne M. Neubauer, Gregory M. Lanza & Samuel A. Wickline. 2008. Nanoparticles in Biomedical Imaging. Nanoparticles in Biomedical Imaging 163 182 .
I. N. Kuznetsova & L. P. Rybakova. (2008) Blood serum protein sorption on the surface of perfluorocarbon emulsion particles. Pharmaceutical Chemistry Journal 41:12, pages 662-665.
Crossref
Pedro Cabrales, Amy G. Tsai & Marcos Intaglietta. (2007) Perfluorocarbon in Microcirculation During Ischemia Reperfusion. Journal of the American College of Surgeons 204:2, pages 225-235.
Crossref
Marcos IntagliettaPedro CabralesAmy G. Tsai. (2006) MICROVASCULAR PERSPECTIVE OF OXYGEN-CARRYING AND -NONCARRYING BLOOD SUBSTITUTES. Annual Review of Biomedical Engineering 8:1, pages 289-321.
Crossref
Shelton D. Caruthers, Anne M. Neubauer, Frank D. Hockett, Rolf Lamerichs, Patrick M. Winter, Michael J. Scott, Patrick J. Gaffney, Samuel A. Wickline & Gregory M. Lanza. (2006) In Vitro Demonstration Using 19F Magnetic Resonance to Augment Molecular Imaging With Paramagnetic Perfluorocarbon Nanoparticles at 1.5 Tesla. Investigative Radiology 41:3, pages 305-312.
Crossref
Peter E. Keipert. 2006. Blood Substitutes. Blood Substitutes 312 323 .
Robert F. Shaw & Thomas J. Richard. 2006. Blood Substitutes. Blood Substitutes 298 311 .
O. Habler, A. Pape, J. Meier & B. Zwißler. (2005) Künstliche Sauerstoffträger als Alternative zur BluttransfusionArtificial oxygen carriers as an alternative to red blood cell transfusion. Der Anaesthesist 54:8, pages 741-754.
Crossref
Yorck Olaf Schumacher & Michael Ashenden. (2004) Doping with Artificial Oxygen Carriers. Sports Medicine 34:3, pages 141-150.
Crossref
Markus Paxian, Steve A. Keller, Toan T. Huynh & Mark G. Clemens. (2003) Perflubron Emulsion Improves Hepatic Microvascular Integrity and Mitochondrial Redox State After Hemorrhagic Shock. Shock 20:5, pages 449-457.
Crossref
Donald J. AbrahamBarbara Campanini, Stefano Bruno, Samanta Raboni & Andrea Mozzarelli. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 385 441 .
Brian Corrigan. (2002) Beyond EPO. Clinical Journal of Sport Medicine 12:4, pages 242-244.
Crossref
M. Lamy, M. Mathy-Hartert & G. Deby-Dupont. 1998. Tissue Oxygenation in Acute Medicine. Tissue Oxygenation in Acute Medicine 332 351 .
Jean G. Riess. (2001) Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft . Chemical Reviews 101:9, pages 2797-2920.
Crossref
Yu-Chih Hsu & Ching-An Peng. (2001) Diminution of Phagocytosed Perfluorocarbon Emulsions Using Perfluoroalkylated Polyethylene Glycol Surfactant. Biochemical and Biophysical Research Communications 283:4, pages 776-781.
Crossref
Marie-Pierre Krafft. (2001) Les émulsions de fluorocarbures (PFC) : Des transporteurs d'oxygène injectables efficaces et facilement détectables. Revue Française des Laboratoires 2001:331, pages 55-59.
Crossref
Christopher P. Stowell, Jack Levin, Bruce D. Spiess & Robert M. Winslow. (2002) Progress in the development of RBC substitutes. Transfusion 41:2, pages 287-299.
Crossref
Jean G. Riess. 2000. Fluorine Chemistry at the Millennium. Fluorine Chemistry at the Millennium 385 431 .
Franz von Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe, Margitta Albinus, Gudrun Amschler, Erwin von Angerer, C. Arras-Reiter, Andrea Bauer, Pia Bauer, Winfried Beil, Thorsten Beyrich, Katja Binder, Roswitha Böhme, Hans-Hubertus Borchert, Franz Bossle, Franz Bracher, Helmut Bräunlich, Ellen Bretschneider, Regina Brigelius-Flohé, Kerstin Brinkmann, Axel Büge, Wolfram Christ, Monika Cimbollek, Rolf Daniels, Gerd Dannhardt, Hans-Jürgen Duchstein, Kurt Eger, Petra Eichhorn, Michael Engler, Thomas Erker, Peter Felfe, Alfred Fenyves, Reinhard Fescharek, Carmen Frackenpohl, August Wilhelm Frahm, Margarete Frahm, Volker Franke, Ulrich Franken, Detlef Geffken, Uli Geis, Erika Glusa, Berthold Göber, Peter Ndive Gobina, Werner Golder, Margarete Goppelt-Strübe, Katharina Götte, Erkme Gottstein, Michael Grosam, Markus von Gruchalla, Michael Gütschow, Annette Häfner, Boris Haluszczynski, Achim Harder, Sabine Hartmann, Susanne Hartmann, Dieter Heber, Gerhard Heinemeyer, Eberhard Heller, Dietrich von Herrath, J. Hilfenhaus, Ute Hoffmann-Schollmayer, Bernhard Hofmann, Christian Holpert, Ute Hübner-Steiner, Elisabeth Inkmann, Jens Jürgens, Brigitte Kaiser, Dieter-Abbo Kalbhen, Hans Kemmler, Werner Kiefer, Christoph Klett, Stephanie Klett, Martin Klingmüller, Hans-Peter Klöcking, Gerd Kobal, Axel Kramer, Mareta Kreher, M. Krüger, Markus Kuhn, Marion Sylvia Lehner, Detlef Leopoldt, Georg Liedtke, Detlef Manns, Wolfgang Matthiessen, Andreas Maurer, Wolfgang Meindl, Klaus Menges, Paul Messinger, Frank Peter Meyer, Wolfgang Meyerhof, Manfred Moos, Rudolf Morgenstern, Klaus Müller, Walter E. Müller, Corina Nachtsheim, Tilo Netzer, Michael Neugebauer, Werner Neupert, Peter Nickel, Peter Nuhn, Bernd Nürnberg, H. Oelschläger, Joachim Oertel, Michael Oettel, Hartmut Oßwald, Robert Ott, Tilmann Ott, Thomas Otzen, Peter Pachaly, Helmut Pelzer, Karl-Uwe Petersen, Rainer Pick, Martina Pickert, Andreas Pies, Eberhard Reimann, Joachim Richter, Kai Riecke, Suzanne Ritter, Hans Rommelspacher, Ulrich Rose, Gernot Roth, Gerhard Rücker, Judith Schäfer, Joachim G. Schantl, Helmut Schlager, Hildegard Schleinitz, Max Schmauß, Helmut Schmidhammer, Gerhard Schmidt, Timo Schmidt, B. Schneeweiß, Johannes Schräder, Thomas Schulz, Gert Schulze, Peter Schwanz, Johannes Schweiger, Gisela Skopp, Gisela Skorka, Kai Smolinka, Ulrich Speck, Ralf Stahlmann, Herbert Stein, Karlheinz Stiefvater, Karl-Heinz Surborg, Ulf Sürig, Hubert Szelényi, Istvan Szelenyi, Alfred Täufel, Ruth Thieroff-Ekerdt, Reinhard Troschütz, Michael Verborg, Eugen J. Verspohl, Sabine Vogel, Franz-Josef Volk, Thomas Vorwerk, Jürgen Wallmann, Martin Wenzel, Marion Weyandt-Spangenberg, Sandra Wich, Reinhold Wintersteiger, Frauke Woltmann, Beate Wüst, G. Zilow & A. Kluge. 1999. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 387 481 .
M.P Krafft & J.G Riess. (1998) Highly fluorinated amphiphiles and colloidal systems, and their applications in the biomedical field. A contribution. Biochimie 80:5-6, pages 489-514.
Crossref
Jürgen Fuchs & Jens Thiele. (1998) The Role of Oxygen in Cutaneous Photodynamic Therapy. Free Radical Biology and Medicine 24:5, pages 835-847.
Crossref
Minakshi Sukumar, Mahesh Bommaraju, John E. Fisher, Frederick C. MorinIIIIII, Michele C. Papo, Bradley P. Fuhrman, Lynn J. Hernan & Corinne Lowe Leach. (1998) High-frequency partial liquid ventilation in respiratory distress syndrome: hemodynamics and gas exchange. Journal of Applied Physiology 84:1, pages 327-334.
Crossref
J.G. Riess & P.E. Keipert. 1998. Blood Substitutes, Present and Future Perspectives. Blood Substitutes, Present and Future Perspectives 91 102 .
Jon E. Rossman, Michael G. Caty, Shan Zheng, Hratch L. Karamanoukian, Kuldip Thusu, Richard G. Azizkhan & Paresh Dandona. (1997) Mucosal Protection from Intestinal Ischemia–Reperfusion Reduces Oxidant Injury to the Lung. Journal of Surgical Research 73:1, pages 41-46.
Crossref
Giorgos Alevisopoulos, Maria Stefanidou, Margarita Pagou, Theodora Siatra-Papastaikoudi & Antonios Koutselinis. (2020) The Effects of Two New Amphetamine-like Derivatives on the Phagocytic Ability of the Protozoan, Tetrahymena pyriformis . Alternatives to Laboratory Animals 25:5, pages 547-553.
Crossref
Stephen F. Flaim. 1997. Advances in Blood Substitutes. Advances in Blood Substitutes 91 132 .
Gregory M. LanzaKirk D. WallaceMichael J. ScottWilliam P. CacherisDana R. AbendscheinDonald H. ChristyAngela M. SharkeyJames G. MillerPatrick J. GaffneySamuel A. Wickline. (1996) A Novel Site-Targeted Ultrasonic Contrast Agent With Broad Biomedical Application. Circulation 94:12, pages 3334-3340.
Crossref
Thao D. Le, Rebecca A. Arlauskas & Jeffry G. Weers. (1996) Characterization of the lipophilicity of fluorocarbon derivatives containing halogens or hydrocarbon blocks. Journal of Fluorine Chemistry 78:2, pages 155-163.
Crossref

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