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Review Article

The contraceptive vaginal ring, NuvaRing®, a decade after its introduction

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Pages 415-427 | Published online: 31 Oct 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (10)

Valentina Elisabetta Bounous, Silvia Actis, Roberta Rosso, Margherita Giorgi, Lara Tiranini, Rossella Elena Nappi & Nicoletta Biglia. (2023) No-daily hormonal contraception today: general overview and application in specific clinical settings. Gynecological Endocrinology 39:1.
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Peter Boyd, Ruth Merkatz, Bruce Variano & R. Karl Malcolm. (2020) The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals. Expert Opinion on Drug Delivery 17:11, pages 1519-1540.
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Elizabeth A. Micks & Jeffrey T. Jensen. (2020) A technology evaluation of Annovera: a segesterone acetate and ethinyl estradiol vaginal ring used to prevent pregnancy for up to one year. Expert Opinion on Drug Delivery 17:6, pages 743-752.
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Patricio Barriga Pooley, Andrea Von Hoveling, Guillermo Galán & Jorge López Berroa. (2020) Analysis and new contraception frontiers with combined vaginal rings. Gynecological Endocrinology 36:6, pages 475-478.
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Ingrid Duijkers, Christine Klipping, Doris Heger-Mahn, Ghassan N. Fayad, Tara L. Frenkl, Sandra M. Cruz & Tjeerd Korver. (2018) Phase II dose-finding study on ovulation inhibition and cycle control associated with the use of contraceptive vaginal rings containing 17β-estradiol and the progestagens etonogestrel or nomegestrol acetate compared to NuvaRing. The European Journal of Contraception & Reproductive Health Care 23:4, pages 245-254.
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Guang Sheng Fan, Mulan Ren, Wen Di, Ping Su, Qin Chang, Shuying Wu, Yun Qin, Tjeerd Korver, Maya Marintcheva-Petrova, Carol Yacik, Christine McCrary Sisk & Guoqin Wang. (2016) Efficacy and safety of the contraceptive vaginal ring (NuvaRing) compared with a combined oral contraceptive in Chinese women: a 1-year randomised trial. The European Journal of Contraception & Reproductive Health Care 21:4, pages 303-309.
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Emma R Liechty, Ingrid L Bergin & Jason D Bell. (2015) Animal models of contraception: utility and limitations. Open Access Journal of Contraception 6, pages 27-35.
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Salvatore Caruso, Stefano Cianci, Chiara Malandrino, Carla Cicero, Lucia Lo Presti & Antonio Cianci. (2014) Quality of sexual life of women using the contraceptive vaginal ring in extended cycles: Preliminary report. The European Journal of Contraception & Reproductive Health Care 19:4, pages 307-314.
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Edith Weisberg. (2014) Developments in contraception. Expert Opinion on Pharmacotherapy 15:2, pages 203-210.
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Articles from other publishers (27)

Gergő D. Tóth, Nikolett Kállai-Szabó, Miléna Lengyel, Károly Süvegh, Ferenc Ender, Gábor Katona, Adrienn Kazsoki, Romána Zelkó, István Antal, György T. Balogh & Diána Balogh-Weiser. (2023) Nanoformulation of lipase from Porcine pancreas by electrospinning as a novel alternative for enzyme-based per os therapies. Journal of Molecular Liquids 389, pages 122819.
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Ping Teresa Yeh, Hunied Kautsar, Caitlin E Kennedy & Mary E Gaffield. (2022) Values and preferences for contraception: A global systematic review. Contraception 111, pages 3-21.
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Yousuf Mohammed, Amy Holmes, Philip Chi Lip Kwok, Tushar Kumeria, Sarika Namjoshi, Mohammad Imran, Lana Matteucci, Masood Ali, Waiting Tai, Heather A.E. Benson & Michael S. Roberts. (2022) Advances and future perspectives in epithelial drug delivery. Advanced Drug Delivery Reviews 186, pages 114293.
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Rossella Nappi, Lara Tiranini, Simona Sacco, Eleonora De Matteis, Roberto De Icco & Cristina Tassorelli. (2022) Role of Estrogens in Menstrual Migraine. Cells 11:8, pages 1355.
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Kunal M. AgavaneSonal B. Ombase. (2022) Contraceptive Vaginal Ring: Nuvaring. Research Journal of Science and Technology, pages 73-76.
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Cameron James Parkin, Sally Beath & Krishan Rasiah. (2021) A NuvaRing caught in the wrong spot . ANZ Journal of Surgery 92:1-2, pages 259-262.
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Thérèse Delvaux, Vicky Jespers, Lenka Benova & Janneke van de Wijgert. (2021) Acceptability and Satisfaction of Contraceptive Vaginal Rings in Clinical Studies: A Systematic Review and Narrative Synthesis. Frontiers in Global Women's Health 2.
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Sarah Cipriani, Tommaso Todisco, Irene Scavello, Vincenza Di Stasi, Elisa Maseroli & Linda Vignozzi. (2019) Obesity and hormonal contraception: an overview and a clinician’s practical guide. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity 25:5, pages 1129-1140.
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Caitlin E. Kennedy, Ping Teresa Yeh & Mary E. Gaffield. (2020) Contraception values and preferences: protocol and methods for a global systematic review. Contraception 101:2, pages 69-73.
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Rachel S. Mandelbaum & Donna Shoupe. 2020. The Handbook of Contraception. The Handbook of Contraception 73 96 .
Herman Weiss, Bridget Martell, Ginger D. Constantine, Sarah M. Davis, Justin D. Vidal, Philip R. Mayer, Martin Doorbar & David R. Friend. (2019) Pharmacokinetics and tolerability of a novel progesterone intravaginal ring in sheep. Drug Delivery and Translational Research 9:5, pages 1008-1016.
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Claudia Mac Donald Bley Nascimento, Andréa Maria Novaes Machado, João Carlos de Campos Guerra, Eduardo Zlotnik, Dirceu Hamilton Cordeiro Campêlo, Paulo Kauffman, Hilton Waksman, Nelson Wolosker, Sérgio Podgaec & Nelson Hamerschlak. (2019) Consensus on the investigation of thrombophilia in women and clinical management. Einstein (São Paulo) 17:3.
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Sara E. Vargas, Miriam M. Midoun, Melissa Guillen, Melissa L. Getz, Kristen Underhill, Caroline Kuo, Kate M. Guthrie, Tyler S. Kaiser, Jaime Ramirez, Julia G. Shaw & Kelley A. Smith. (2019) A Qualitative Systematic Review of Women's Experiences Using Contraceptive Vaginal Rings: Implications for New Technologies. Perspectives on Sexual and Reproductive Health 51:2, pages 71-80.
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Michelle C. Fox, Christine Klipping, Allison Martin Nguyen, Tara L. Frenkl, Sandra M. Cruz, Yinna Wang & Tjeerd Korver. (2019) A phase 2b multicenter, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of vaginal rings containing nomegestrol acetate or etonogestrel and 17β-estradiol in the treatment of women with primary dysmenorrhea. Contraception 99:2, pages 125-130.
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Santiago Palacios & Mariella Lilue. (2018) Hormonal Contraception and Sexuality. Current Sexual Health Reports 10:4, pages 345-352.
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Eleanor McLellan-Lemal, Roman Gvetadze, Mitesh A Desai, Esther M Makanga, Yi Pan, Richard E Haaland, Angela N Holder, Victor Mudhune, Tiffany Williams & Taraz Samandari. (2018) Non-adherence among women enrolled in a contraceptive vaginal ring use study in Kisumu, Kenya, 2014-2015. Journal of Global Health Reports 2.
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Kathryn J. LaRoche, Eva Gross, Grace Sheehy & Angel M. Foster. (2018) Put a Ring in It: Exploring Women's Experiences with the Contraceptive Vaginal Ring in Ontario. Women's Health Issues 28:5, pages 415-420.
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Andrea Ries Thurman, Jill L. Schwartz, Vivian Brache, Meredith R. Clark, Timothy McCormick, Neelima Chandra, Mark A. Marzinke, Frank Z. Stanczyk, Charlene S. Dezzutti, Sharon L. Hillier, Betsy C. Herold, Raina Fichorova, Susana N. Asin, Christiane Rollenhagen, Debra Weiner, Patrick Kiser & Gustavo F. Doncel. (2018) Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women. PLOS ONE 13:6, pages e0199778.
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Evelyne Kestelyn, Jennifer Ilo Van Nuil, Marie Michelle Umulisa, Grace Umutoni, Alice Uwingabire, Lambert Mwambarangwe, Mireille Uwineza, Stephen Agaba, Tania Crucitti, Janneke van de Wijgert & Thérèse Delvaux. (2018) High acceptability of a contraceptive vaginal ring among women in Kigali, Rwanda. PLOS ONE 13:6, pages e0199096.
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Evelyne Kestelyn, Stephen Agaba, Jennifer Ilo Van Nuil, Mireille Uwineza, Marie Michelle Umulisa, Lambert Mwambarangwe, Jean Claude Ndagijimana, Irith De Baetselier, Jozefien Buyze, Thérèse Delvaux, Tania Crucitti, Vicky Jespers & Janneke H. H. M. van de Wijgert. (2018) A randomised trial of a contraceptive vaginal ring in women at risk of HIV infection in Rwanda: Safety of intermittent and continuous use. PLOS ONE 13:6, pages e0197572.
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Jenny K.R. Francis, Lauren Dapena Fraiz, Marina Catallozzi & Susan L. Rosenthal. (2016) Qualitative Analysis of Sexually Experienced Female Adolescents: Attitudes about Vaginal Health. Journal of Pediatric and Adolescent Gynecology 29:5, pages 496-500.
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Eleanor McLellan-Lemal, Deborah A Gust, Roman Gvetadze, Melissa Furtado, Fredrick O Otieno, Mitesh Desai, Clement Zeh, Taraz Samandari, Beatrice Nyagol & Esther M Makang. (2016) Characteristics of women screened for a contraceptive intravaginal ring study in Kisumu, Kenya, 2014. Research Journal of Women's Health 3:1, pages 1.
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Heather C. M. Allaway, Rebecca J. Mallinson & Mary Jane De Souza. 2016. Exercise and Human Reproduction. Exercise and Human Reproduction 287 302 .
Alessandro Gambera, Fedela Corda, Rosetta Papa, Carlo Bastianelli, Sandra Bucciantini, Salvatore Dessole, Pasquale Scagliola, Nadia Bernardini, Daniela de Feo & Fabiola Beligotti. (2015) Observational, prospective, multicentre study to evaluate the effects of counselling on the choice of combined hormonal contraceptives in Italy—the ECOS (Educational COunselling effectS) study. BMC Women's Health 15:1.
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Sarah M.R. Hardman & Ailsa E. Gebbie. (2014) The contraception needs of the perimenopausal woman. Best Practice & Research Clinical Obstetrics & Gynaecology 28:6, pages 903-915.
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Denise Leite Maia Monteiro, Ricardo Vasconcelos Bruno, Zuleide A. F. Cabral, Célia Regina da Silva, Danielle Bittencourt Sodré Barmpas & Nádia Cristina Pinheiro Rodrigues. (2014) Experience of more than 3000 cycles of Brazilian women using the contraceptive vaginal ring (nuvaring<sup>&reg;</sup>). Open Journal of Obstetrics and Gynecology 04:01, pages 10-15.
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Paula Briggs. 2013. Contraception. Contraception 99 105 .

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