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Research Article

Biochemical efficacy of vitamin D in ameliorating endocrine and metabolic disorders in diabetic rats

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Pages 591-596 | Received 14 Jul 2013, Accepted 08 Oct 2013, Published online: 20 Nov 2013

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Xiaoyu He, Yu Luo, Jianan Hao, Cuiyu Wang, Kexin Gan, Yunfeng Zhen & Luping Ren. (2022) Association Between Serum Vitamin D Levels and Ketosis Episodes in Hospitalized Patients with Newly Diagnosed Ketosis-Prone Type 2 Diabetes. Diabetes, Metabolic Syndrome and Obesity 15, pages 3821-3829.
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Mona A. Said. (2022) Vitamin D attenuates endothelial dysfunction in streptozotocin induced diabetic rats by reducing oxidative stress. Archives of Physiology and Biochemistry 128:4, pages 959-963.
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Arslan Hussain Lodhi, Fiaz-ud-Din Ahmad, Kainat Furwa & Asadullah Madni. (2021) Role of Oxidative Stress and Reduced Endogenous Hydrogen Sulfide in Diabetic Nephropathy. Drug Design, Development and Therapy 15, pages 1031-1043.
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Feizhou Xie, Meiling Wu, Ben Lai, Michael Halim, Shanlin Liu & Dongyun Shi. (2021) Effects of redox interference on the pancreatic mitochondria and the abnormal blood glucose. Free Radical Research 55:2, pages 119-130.
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Tahany Saleh Aldayel, Ghedeir M. Alshammari, Ulfat Mohammed Omar, Mary H. Grace, Mary Ann Lila & Mohammed A. Yahya. (2020) Hypoglycaemic, insulin releasing, and hepatoprotective effect of the aqueous extract of Aloe perryi Baker resin (Socotran Aloe) in streptozotocin-induced diabetic rats. Journal of Taibah University for Science 14:1, pages 1671-1685.
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Anastasios Serbis, Vasileios Giapros, Konstantinos Tsamis, Foteini Balomenou, Assimina Galli-Tsinopoulou & Ekaterini Siomou. (2023) Beta Cell Dysfunction in Youth- and Adult-Onset Type 2 Diabetes: An Extensive Narrative Review with a Special Focus on the Role of Nutrients. Nutrients 15:9, pages 2217.
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Fatima El Zahra M. Fathi, Kadry M. Sadek, Asmaa F. Khafaga, Abdel Wahab Al senosy, Hanan A. Ghoniem, Sahar Fayez & Mohamed F. Zeweil. (2022) Vitamin D regulates insulin and ameliorates apoptosis and oxidative stress in pancreatic tissues of rats with streptozotocin-induced diabetes. Environmental Science and Pollution Research 29:60, pages 90219-90229.
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Josephine Yu, Preeti Sharma, Christian M. Girgis & Jenny E. Gunton. (2022) Vitamin D and Beta Cells in Type 1 Diabetes: A Systematic Review. International Journal of Molecular Sciences 23:22, pages 14434.
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Eva Tvrdá, Ján Kováč, Filip Benko, Michal Ďuračka, Anikó Varga, Oľga Uličná, Viera Almášiová, Marcela Capcarová & Mária Chomová. (2022) Characterization of the structural, oxidative, and immunological features of testis tissue from Zucker diabetic fatty rats. Open Life Sciences 17:1, pages 1383-1397.
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Rongpeng Gong, Xin Tang, Ziying Jiang, Gang Luo, Chaofan Dong & Xiuxia Han. (2022) Serum 25(OH)D Levels Modify the Association between Triglyceride and IR: A Cross-Sectional Study. International Journal of Endocrinology 2022, pages 1-8.
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Nasr E. Nasr & Kadry M. Sadek. (2022) Role and mechanism(s) of incretin-dependent therapies for treating diabetes mellitus. Environmental Science and Pollution Research 29:13, pages 18408-18422.
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Ke Xiong, Jinyu Wang & Aiguo Ma. (2021) Adjunctive vitamin A and D for the glycaemic control in patients with concurrent type 2 diabetes and tuberculosis: a randomised controlled trial. British Journal of Nutrition 127:4, pages 556-562.
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Maria Mercedes Chang Villacreses, Rudruidee Karnchanasorn, Panadeekarn Panjawatanan, Horng-Yih Ou & Ken C Chiu. (2021) Conundrum of vitamin D on glucose and fuel homeostasis. World Journal of Diabetes 12:9, pages 1363-1385.
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Xueqin Du, Yi Liu, Chunhui Zhao, Jingzhou Fang, Xiangna Wang & Limin Wei. (2019) Changes of serum 25(OH) D3 and IGF-1 levels in patients with thyroid nodules. BMC Endocrine Disorders 19:1.
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Zoé Maria GuareschiVanessa Marieli CeglarekPatrick Fontes RodriguesLuiz Pierre HuningCintia FestinalliJoão Paulo de Arruda AmorimSabrina Grassiolli. (2019) Exercise and Vitamin D Supplementation Modify Spleen Morphology in Lean, but not, in Monosodium-Glutamate-Obese Rats. Journal of Spleen and Liver Research 1:3, pages 1-14.
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Zoé M. Guareschi, Ana C. Valcanaia, Vanessa M. Ceglarek, Pamela Hotz, Bruna K. Amaral, Domwesley W. de Souza, Thainan A. de Souza, Tarlliza Nardelli, Thiago R. Ferreira, Nayara C. Leite, Camila Lubackzeuski, Henriette R. de O. Emilio & Sabrina Grassiolli. (2019) The effect of chronic oral vitamin D supplementation on adiposity and insulin secretion in hypothalamic obese rats. British Journal of Nutrition 121:12, pages 1334-1344.
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Kadry M. Sadek, Mohamed A. Lebda & Tarek K. Abouzed. (2019) The possible neuroprotective effects of melatonin in aluminum chloride-induced neurotoxicity via antioxidant pathway and Nrf2 signaling apart from metal chelation. Environmental Science and Pollution Research 26:9, pages 9174-9183.
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Kadry M. Sadek, Mohamed A. Lebda, Tarek K. Abouzed, Sherif M. Nasr & Yasser EL-Sayed. (2018) The molecular and biochemical insight view of lycopene in ameliorating tramadol-induced liver toxicity in a rat model: implication of oxidative stress, apoptosis, and MAPK signaling pathways. Environmental Science and Pollution Research 25:33, pages 33119-33130.
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Kadry M. Sadek, Mohamed A. Lebda, Nasr E. Nasr, Sherif M. Nasr & Yasser EL-Sayed. (2018) Role of lncRNAs as prognostic markers of hepatic cancer and potential therapeutic targeting by S-adenosylmethionine via inhibiting PI3K/Akt signaling pathways. Environmental Science and Pollution Research 25:20, pages 20057-20070.
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Jerine Peter Simon, Udhaya Lavinya Baskaran, Kadar Basha Shallauddin, Giridharan Ramalingam & Sabina Evan Prince. (2018) Evidence of antidiabetic activity of Spirulina fusiformis against streptozotocin-induced diabetic Wistar albino rats. 3 Biotech 8:2.
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Kadry M. Sadek, Mohamed A. Lebda, Sherif M. Nasr & Moustafa Shoukry. (2017) Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways. Biomedicine & Pharmacotherapy 92, pages 1085-1094.
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Mohamed Mahmoud Elseweidy, Rawia Sarhan Amin, Hebatallah Husseini Atteia & Maha Abdo Ali. (2017) Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylation in diabetic rats. Biomedicine & Pharmacotherapy 85, pages 155-159.
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Dalia K. Mostafa, Rasha A. Nasra, Noha Zahran & Mohammed T. Ghoneim. (2016) Pleiotropic protective effects of Vitamin D against high fat diet-induced metabolic syndrome in rats: One for all. European Journal of Pharmacology 792, pages 38-47.
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Sunmin Park, Da Sol Kim & Suna Kang. (2016) Vitamin D deficiency impairs glucose-stimulated insulin secretion and increases insulin resistance by reducing PPAR-γ expression in nonobese Type 2 diabetic rats. The Journal of Nutritional Biochemistry 27, pages 257-265.
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Samah M. Fathy & Ehab A. Drees. (2016) Protective effects of Egyptian cloudy apple juice and apple peel extract on lipid peroxidation, antioxidant enzymes and inflammatory status in diabetic rat pancreas. BMC Complementary and Alternative Medicine 16:1.
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William T. Moore, Suzanne M. Bowser, Dane W. Fausnacht, Linda L. Staley, Kyung-Shin Suh & Dongmin Liu. (2015) Beta Cell Function and the Nutritional State: Dietary Factors that Influence Insulin Secretion. Current Diabetes Reports 15:10.
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Oytun Erbaş, Volkan Solmaz, Dürdane Aksoy, Altuğ Yavaşoğlu, Mustafa Sağcan & Dilek Taşkıran. (2014) Cholecalciferol (vitamin D 3) improves cognitive dysfunction and reduces inflammation in a rat fatty liver model of metabolic syndrome. Life Sciences 103:2, pages 68-72.
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