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Original Article

A common feature-based 3D-pharmacophore model generation and virtual screening: identification of potential PfDHFR inhibitors

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Pages 635-645 | Received 26 Jul 2009, Accepted 07 Oct 2009, Published online: 08 Dec 2009

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TaeHun Kim, Mohammad N. Morshed, Ashwini M. Londhe, Ji W. Lim, Ha E. Lee, Suengmok Cho, Sung J. Cho, Hayoung Hwang, Sang M. Lim, Jae Y. Lee, Jiyoun Lee & Ae N. Pae. (2021) The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 831-846.
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Anu Manhas, Mohsin Y. Lone & Prakash C. Jha. (2019) Multicomplex-based pharmacophore modeling in conjunction with multi-target docking and molecular dynamics simulations for the identification of PfDHFR inhibitors. Journal of Biomolecular Structure and Dynamics 37:16, pages 4181-4199.
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Sheenu Abbat, Vaibhav Jain & Prasad V. Bharatam. (2015) Origins of the specificity of inhibitor P218 toward wild-type and mutant PfDHFR: a molecular dynamics analysis. Journal of Biomolecular Structure and Dynamics 33:9, pages 1913-1928.
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