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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 28, 2013 - Issue 6
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Research Article

In vivo and in vitro effect of androstene derivatives as 5α-reductase type 1 enzyme inhibitors

Eugene BratoeffDepartment of Pharmacy, Faculty of Chemistry, National University of Mexico City, Mexico, D. F., Mexico
,
Araceli SánchezDepartment of Biological Systems and Animal Production Metropolitan University-Xochimilco, Mexico, D. F., Mexico
,
Yazmín ArellanoDepartment of Pharmacy, Faculty of Chemistry, National University of Mexico City, Mexico, D. F., Mexico
,
Yvonne HeuzeDepartment of Biological Systems and Animal Production Metropolitan University-Xochimilco, Mexico, D. F., Mexico
,
Juan SorianoDepartment of Pathology of the General Hospital of Mexico (SS), Mexico, D. F., Mexico
&
Marisa CabezaDepartment of Biological Systems and Animal Production Metropolitan University-Xochimilco, Mexico, D. F., MexicoCorrespondence[email protected].
Pages 1247-1254 | Received 11 Jul 2012, Accepted 11 Sep 2012, Published online: 10 Oct 2012

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Araceli Sánchez-Márquez, Yazmín Arellano, Eugene Bratoeff, Yvonne Heuze, Karen Córdova, Gladys Nieves, Juan Soriano & Marisa Cabeza. (2016) Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1170-1176.
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Articles from other publishers (7)

Marisa Cabeza, Luis A. Menes, Evelyn Fuentes, Iván BahenaYvonne Heuze. (2023) Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells. Oriental Journal Of Chemistry 39:3, pages 523-532.
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Shengnan Xiao, Zhe Lin, Xude Wang, Jincai Lu & Yuqing Zhao. (2020) Synthesis and Cytotoxicity Evaluation of Panaxadiol Derivatives. Chemistry & Biodiversity 17:1.
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Liyan Lv, Jincai Lu, Hongyu Zhang, Xude Wang, Guangyue Su, Huri Piao & Yuqing Zhao. (2019) Acylation of 25-hydroxyprotopanaxatriol with aromatic acids increases cytotoxicity. Fitoterapia 137, pages 104279.
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Jukkarin SrivilaiGenet MinaleC. Norman ScholfieldKornkanok Ingkaninan. (2019) Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors. ASSAY and Drug Development Technologies 17:2, pages 44-57.
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Fan-Zhi Qu, Sheng-Nan Xiao, Xu-De Wang, Yan Zhang, Guang-Yue Su & Yu-Qing Zhao. (2019) Semi-synthesis and anti-tumor activity of novel 25-OCH3-PPD derivatives incorporating aromatic moiety. Bioorganic & Medicinal Chemistry Letters 29:2, pages 189-193.
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Yazmín Arellano, Eugene Bratoeff, Yvonne Heuze, Marisol Bravo, Juan Soriano & Marisa Cabeza. (2018) Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1. Bioorganic & Medicinal Chemistry 26:14, pages 4058-4064.
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Alejandra Chávez-Riveros, Eugene Bratoeff, Yvonne Heuze, Juan Soriano, Isabel Moreno, Araceli Sánchez-Márquez & Marisa Cabeza. (2015) Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5α-Reductase. Archiv der Pharmazie 348:11, pages 808-816.
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