Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue 2
Submit an article Journal homepage
3,321
Views
29
CrossRef citations to date
0
Altmetric
Review Article

Recent advances in novel heterocyclic scaffolds for the treatment of drug-resistant malaria

Sahil KumarDepartment of Pharmaceutical Chemistry, Indo-Soviet Friendship (I.S.F.) College of Pharmacy, Moga, Punjab, India, ;Faculty of Pharmacy, Punjab Technical University, Jalandhar, Kapurthala, India,
,
Rajesh K. SinghDepartment of Pharmaceutical Chemistry, Shivalik College of Pharmacy, Nangal, Dist. Rupnagar, Punjab, India, and
,
Babita PatialDepartment of Pharmaceutical Chemistry, Indo-Soviet Friendship (I.S.F.) College of Pharmacy, Moga, Punjab, India,
,
Sachin GoyalDepartment of Pharmaceutical Chemistry, Indo-Soviet Friendship (I.S.F.) College of Pharmacy, Moga, Punjab, India,
&
T. R. BhardwajDepartment of Pharmaceutical Chemistry, Indo-Soviet Friendship (I.S.F.) College of Pharmacy, Moga, Punjab, India, ;Department of Pharmaceutical Chemistry, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, IndiaCorrespondence[email protected]
Pages 173-186 | Received 22 Nov 2014, Accepted 19 Jan 2015, Published online: 16 Mar 2015

Citations (29)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Abdrrahman Shemsu Surur, Solomon Assefa Huluka, Melese Legesse Mitku & Kaleab Asres. (2020) Indole: The After Next Scaffold of Antiplasmodial Agents?. Drug Design, Development and Therapy 14, pages 4855-4867.
Read now
Jean Guillon, Anita Cohen, Clotilde Boudot, Alessandra Valle, Vittoria Milano, Rabindra Nath Das, Aurore Guédin, Stéphane Moreau, Luisa Ronga, Solène Savrimoutou, Maxime Demourgues, Elodie Reviriego, Sandra Rubio, Sandie Ferriez, Patrice Agnamey, Cécile Pauc, Serge Moukha, Pascale Dozolme, Sophie Da Nascimento, Pierre Laumaillé, Anne Bouchut, Nadine Azas, Jean-Louis Mergny, Catherine Mullié, Pascal Sonnet & Bertrand Courtioux. (2020) Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 432-459.
Read now
Jean Guillon, Anita Cohen, Nassima Meriem Gueddouda, Rabindra Nath Das, Stéphane Moreau, Luisa Ronga, Solène Savrimoutou, Louise Basmaciyan, Alix Monnier, Myriam Monget, Sandra Rubio, Timothée Garnerin, Nadine Azas, Jean-Louis Mergny, Catherine Mullié & Pascal Sonnet. (2017) Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 547-563.
Read now

Articles from other publishers (26)

Archana Kumari & Rajesh Kumar Singh. (2023) Synthesis, Drug-Likeness Evaluation of Some Heterocyclic Moieties Fused Indole Derivatives as Potential Antioxidants. Combinatorial Chemistry & High Throughput Screening 26:11, pages 2077-2084.
Crossref
Sandra Albenque-Rubio, Jean Guillon, Anita Cohen, Patrice Agnamey, Solène Savrimoutou, Stéphane Moreau, Jean-Louis Mergny, Luisa Ronga, Ioannis Kanavos, Serge Moukha, Pascale Dozolme & Pascal Sonnet. (2023) Synthesis and Antimalarial Evaluation of New 1,3,5-tris[(4-(Substituted-aminomethyl)phenyl)methyl]benzene Derivatives: A Novel Alternative Antiparasitic Scaffold. Drugs and Drug Candidates 2:3, pages 653-672.
Crossref
Elvira R. Zaitseva, Dmitry S. Ivanov, Alexander Yu. Smirnov, Nadezhda S. Baleeva & Mikhail S. Baranov. (2023) Synthesis of 2H-[1,2]oxazino[3,4-c]quinoline-2,5(6H)-diones from 6-oxo-6H-1,2-oxazine-3-carboxylates. Chemistry of Heterocyclic Compounds 59:4-5, pages 327-330.
Crossref
Hiro Mohammed Obaid, Sayran Sattar Sale & Larson Boundenga. (2023) Pharmaceutical activity of a synthetic heterocyclic (C<sub>15</sub>H<sub>12</sub>N<sub>5</sub>OCl) compound on <i>Entamoeba histolytica</i> and <i>Giardia lamblia</i>. Russian Journal of Infection and Immunity 13:1, pages 119-126.
Crossref
Archana Kumari & Rajesh Kumar Singh. (2023) Synthesis, Characterization and ADME Prediction Study of Heterocyclic Moieties-linked Indole Derivatives as Potential Antimicrobial Agents. Letters in Drug Design & Discovery 20:1, pages 40-47.
Crossref
Song-Fang Duan, Lei Song, Hong-Yan Guo, Hao Deng, Xing Huang, Qing-Kun Shen, Zhe-Shan Quan & Xiu-Mei Yin. (2023) Research status of indole-modified natural products. RSC Medicinal Chemistry.
Crossref
Jean Guillon, Anita Cohen, Clotilde Boudot, Sarah Monic, Solène Savrimoutou, Stéphane Moreau, Sandra Albenque-Rubio, Camille Lafon-Schmaltz, Alexandra Dassonville-Klimpt, Jean-Louis Mergny, Luisa Ronga, Mikel Bernabeu de Maria, Jeremy Lamarche, Cristina Dal Lago, Eric Largy, Valérie Gabelica, Serge Moukha, Pascale Dozolme, Patrice Agnamey, Nadine Azas, Catherine Mullié, Bertrand Courtioux & Pascal Sonnet. (2022) Design, Synthesis, and Antiprotozoal Evaluation of New Promising 2,9-Bis[(substituted-aminomethyl)]-4,7-phenyl-1,10-phenanthroline Derivatives, a Potential Alternative Scaffold to Drug Efflux. Pathogens 11:11, pages 1339.
Crossref
Sakshi Choudhary, Archana Kumari, Rajesh Kumar, Sahil Kumar & Rajesh K. Singh. 2022. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I 232 259 .
Pravati Panda, Subhendu Chakroborty & M.V. B. Unnamatla. 2022. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I 167 204 .
Rajesh Kumar, Monika Sharma, Sarita Sharma & Rajesh K. Singh. 2022. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I 105 166 .
Bhawna Chopra, Ashwani Dhingra & Kanaya Lal Dhar. 2022. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I. Key Heterocyclic Cores for Smart Anticancer Drug–Design Part I 57 104 .
Khaled M. Elattar, Ayman Y. El-Khateeb & Sahar E. Hamed. (2022) Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs. RSC Medicinal Chemistry 13:5, pages 522-567.
Crossref
Pallavi H M, Fares Hezam Al-Ostoot, Hamse Kameshwar Vivek & Shaukath Ara Khanum. (2022) Design, docking, synthesis, and characterization of novel N'(2-phenoxyacetyl) nicotinohydrazide and N'(2-phenoxyacetyl)isonicotinohydrazide derivatives as anti-inflammatory and analgesic agents. Journal of Molecular Structure 1247, pages 131404.
Crossref
Galal H. Elgemeie, Rasha A. Azzam, Wafaa A. Zaghary, Ashraf A. Aly, Nadia H. Metwally, Mona O. Sarhan, Elshimaa M. Abdelhafez & Rasha E. Elsayed. 2022. N-Sulfonated-N-Heterocycles. N-Sulfonated-N-Heterocycles 417 446 .
Jean GUILLON, Noël PINAUD, Solène SAVRIMOUTOU, Mathieu MARCHIVIE, Stéphane MOREAU, Sandra ALBENQUE-RUBIO & Pascal SONNET. (2021) Crystal Structure of 1-(3-Ferrocenyl-2-methylpyrrolo[1,2-<i>a</i>]quinoxalin-4-yl)piperazin-4-ium Chloride. X-ray Structure Analysis Online 37:0, pages 65-67.
Crossref
Prinessa Chellan & Peter J. Sadler. (2020) Enhancing the Activity of Drugs by Conjugation to Organometallic Fragments. Chemistry – A European Journal 26:40, pages 8676-8688.
Crossref
Samuel K. Kwofie, Emmanuel Broni, Bismark Dankwa, Kweku S. Enninful, Joshua Teye, Cedar R. Davidson, Josephine B. Nimely, J. Chioma Orizu, Prakasha Kempaiah, Brijesh Rathi & Whelton A. Miller. (2020) Review of Atypical Organometallic Compounds as Antimalarial Drugs. Journal of Chemistry 2020, pages 1-9.
Crossref
Aliyu Wappah Mahmud, Gideon Adamu Shallangwa & Adamu Uzairu. (2020) QSAR and molecular docking studies of 1,3-dioxoisoindoline-4-aminoquinolines as potent antiplasmodium hybrid compounds. Heliyon 6:3, pages e03449.
Crossref
Magne O. Sydnes. 2020. Bioactive Natural Products. Bioactive Natural Products 59 84 .
Anu Rani, Jenny Legac, Philip J. Rosenthal & Vipan Kumar. (2019) Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation. Bioorganic Chemistry 88, pages 102912.
Crossref
Hussien A. Khamees, Yasser H. E. Mohammed, Ananda Swamynayaka, Fares H. Al‐Ostoot, Yusuf Sert, Saad Alghamdi, Shaukath A. Khanum & Mahendra Madegowda. (2019) Molecular Structure, DFT, Vibrational Spectra with Fluorescence Effect, Hirshfeld Surface, Docking Simulation and Antioxidant Activity of Thiazole Derivative. ChemistrySelect 4:15, pages 4544-4558.
Crossref
Mubashir Hassan, Muhammad Athar Abbasi, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Ghulam Hussain, Syed Adnan Ali Shah, Muhammad Shahid & Sung-Yum Seo. (2018) Exploration of synthetic multifunctional amides as new therapeutic agents for Alzheimer's disease through enzyme inhibition, chemoinformatic properties, molecular docking and dynamic simulation insights. Journal of Theoretical Biology 458, pages 169-183.
Crossref
Parteek Prasher & Mousmee Sharma. (2018) Medicinal chemistry of acridine and its analogues. MedChemComm 9:10, pages 1589-1618.
Crossref
Jean Guillon, Anita Cohen, Rabindra Nath Das, Clotilde Boudot, Nassima Meriem Gueddouda, Stéphane Moreau, Luisa Ronga, Solène Savrimoutou, Louise Basmaciyan, Camille Tisnerat, Sacha Mestanier, Sandra Rubio, Sophia Amaziane, Alexandra Dassonville-Klimpt, Nadine Azas, Bertrand Courtioux, Jean-Louis Mergny, Catherine Mullié & Pascal Sonnet. (2018) Design, synthesis, and antiprotozoal evaluation of new 2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline derivatives. Chemical Biology & Drug Design 91:5, pages 974-995.
Crossref
Takeshi Ohkuma & Noriyoshi Arai. (2018) Construction of Unique Heterocyclic Frameworks by Photochemical Reaction of 5- and 6-Membered Heteroaromatics. HETEROCYCLES 96:6, pages 997.
Crossref
Leonid I. Belen’kii & Yulia B. Evdokimenkova. 2018. 173 254 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.