Advanced search
Publication Cover
Toxicology Mechanisms and Methods Volume 24, 2014 - Issue 4
Submit an article Journal homepage
245
Views
40
CrossRef citations to date
0
Altmetric
Research Article

EGCG inhibits Cd2+-induced apoptosis through scavenging ROS rather than chelating Cd2+ in HL-7702 cells

Zhen AnSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Yongmei QiSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Dejun HuangSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Xueyan GuSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Yihong TianSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Ping LiSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
,
Hui LiSchool of Life Sciences, Lanzhou University Lanzhou, GansuChina
&
Yingmei ZhangSchool of Life Sciences, Lanzhou University Lanzhou, GansuChinaCorrespondence[email protected]
 show all
Pages 259-267 | Received 19 Nov 2013, Accepted 29 Dec 2013, Published online: 22 Jan 2014

Citations (40)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Man Chen, Wanmin Liu, Zhiling Li & Wanfen Xiao. (2020) Effect of epigallocatechin-3-gallate (EGCG) on embryos inseminated with oxidative stress-induced DNA damage sperm. Systems Biology in Reproductive Medicine 66:4, pages 244-254.
Read now
Yi Wu, Xuejun Jiang, Kai Yang, Yinyin Xia, Shuqun Cheng, Qianghu Tang, LuLu Bai, Jingfu Qiu & Chengzhi Chen. (2017) Inhibition of α-Synuclein contributes to the ameliorative effects of dietary flavonoids luteolin on arsenite-induced apoptotic cell death in the dopaminergic PC12 cells. Toxicology Mechanisms and Methods 27:8, pages 598-608.
Read now

Articles from other publishers (38)

Shuanghui Wang, Chuhong Chen & Yan Lu. (2023) Epigallocatechin-3-Gallate Reduces Cd-Induced Developmental Toxicity of Bodysize in Caenorhabditis elegans via the PEK-1/eIF-2α/ATF-4 Pathway. Molecules 28:17, pages 6344.
Crossref
Golam Jalal Ahammed, Yaxian Wu, Yameng Wang, Tianmeng Guo, Rubya Shamsy & Xin Li. (2023) Epigallocatechin-3-Gallate (EGCG): A unique secondary metabolite with diverse roles in plant-environment interaction. Environmental and Experimental Botany 209, pages 105299.
Crossref
Kun Xu, Yi Liu, Jinpeng Wang, Yue Wang, Yuyi Zhao, Jinbin Zhao, Beilin Zhang & Guoxi Shao. (2022) Anti-inflammatory Effect of (-)-Epigallocatechin-3- O -gallate on Human Umbilical Vein Endothelial Cells Grown on 316L Stainless Steel via STAT3/NF-κB Signaling . Natural Product Communications 17:8, pages 1934578X2211191.
Crossref
Shomaila Mehmood, Maria Maqsood, Nazia Mahtab, Muhammad Issa Khan, Amna Sahar, Sania Zaib & Shehla Gul. (2022) Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies. Journal of Food Biochemistry 46:8.
Crossref
Vaishali Aggarwal, Hardeep Singh Tuli, Mousumi Tania, Saumya Srivastava, Erin E. Ritzer, Anjana Pandey, Diwakar Aggarwal, Tushar Singh Barwal, Aklank Jain, Ginpreet Kaur, Katrin Sak, Mehmet Varol & Anupam Bishayee. (2022) Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement. Seminars in Cancer Biology 80, pages 256-275.
Crossref
Iwona Zwolak. (2021) Epigallocatechin Gallate for Management of Heavy Metal-Induced Oxidative Stress: Mechanisms of Action, Efficacy, and Concerns. International Journal of Molecular Sciences 22:8, pages 4027.
Crossref
Mohaddeseh Sadat Alavi, Sahar Fanoudi, Mahboobeh Ghasemzadeh Rahbardar, Soghra Mehri & Hossein Hosseinzadeh. (2020) An updated review of protective effects of rosemary and its active constituents against natural and chemical toxicities. Phytotherapy Research 35:3, pages 1313-1328.
Crossref
Lingxue Meng, Jian Liu, Congcong Wang, Zedong Ouyang, Jiahua Kuang, Qihua Pang & Ruifang Fan. (2021) Sex-specific oxidative damage effects induced by BPA and its analogs on primary hippocampal neurons attenuated by EGCG. Chemosphere 264, pages 128450.
Crossref
Xiangyu Cao, Mingyang Fu, Ruochen Bi, Xiaomei Zheng, Baorong Fu, Siqi Tian, Chengying Liu, Qijiu Li & Jianli Liu. (2021) Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway. Chemosphere 263, pages 128346.
Crossref
Mohammad Hossein Asghari, Milad Moloudizargari & Mohammad Abdollahi. 2021. Mitochondrial Physiology and Vegetal Molecules. Mitochondrial Physiology and Vegetal Molecules 689 707 .
Carmen Burgos, Dolores Muñoz-Mingarro, Inmaculada Navarro, Carmen Martín-Cordero & Nuria Acero. (2020) Neuroprotective Potential of Verbascoside Isolated from Acanthus mollis L. Leaves through Its Enzymatic Inhibition and Free Radical Scavenging Ability. Antioxidants 9:12, pages 1207.
Crossref
XiaoXu Han, Lan Li, Tian Xie, Si Chen, Yang Zou, Xin Jin, Sheng Li, Meng Wang, Ning Han, GuanWei Fan, WenGuang Liu & Wei Wang. (2020) “Ferrero-like” nanoparticles knotted injectable hydrogels to initially scavenge ROS and lastingly promote vascularization in infarcted hearts. Science China Technological Sciences 63:11, pages 2435-2448.
Crossref
Zhiyang Wang, Keqing Cao, Dan Wang, Bingjie Hua, Haiyan Zhang & Xin Xie. (2020) Cadmium sulfate induces apoptosis in planarians. Environmental Science and Pollution Research 27:31, pages 39308-39316.
Crossref
Yangbo Zhang, Haiyan Lin, Changwei Liu, Jianan Huang & Zhonghua Liu. (2020) A review for physiological activities of EGCG and the role in improving fertility in humans/mammals. Biomedicine & Pharmacotherapy 127, pages 110186.
Crossref
Fei Fei, Ning Su, Xia Li & Zhou Fei. (2020) Neuroprotection mediated by natural products and their chemical derivatives. Neural Regeneration Research 15:11, pages 2008.
Crossref
Aida Salameh, Stefan Dhein, Marie Mewes, Sophie Sigusch, Philipp Kiefer, Marcel Vollroth, Johannes Seeger & Ingo Dähnert. (2020) Anti-oxidative or anti-inflammatory additives reduce ischemia/reperfusions injury in an animal model of cardiopulmonary bypass. Saudi Journal of Biological Sciences 27:1, pages 18-29.
Crossref
M. Gahramanova. (2019) THE USE OF HERBAL REMEDIES IN THE TREATMENT OF HEPATOBILIARY DISEASES: TRENDS AND PROSPECTS. Biotechnologia acta 12:5, pages 42-62.
Crossref
Yong Chool Boo. (2019) Can Plant Phenolic Compounds Protect the Skin from Airborne Particulate Matter?. Antioxidants 8:9, pages 379.
Crossref
Britt Burton-Freeman, Michał Brzeziński, Eunyoung Park, Amandeep Sandhu, Di Xiao & Indika Edirisinghe. (2019) A Selective Role of Dietary Anthocyanins and Flavan-3-ols in Reducing the Risk of Type 2 Diabetes Mellitus: A Review of Recent Evidence. Nutrients 11:4, pages 841.
Crossref
Liu-Xiang Wang, Yun-Long Shi, Long-Jie Zhang, Kai-Rong Wang, Li-Ping Xiang, Zhuo-Yu Cai, Jian-Liang Lu, Jian-Hui Ye, Yue-Rong Liang & Xin-Qiang Zheng. (2019) Inhibitory Effects of (−)-Epigallocatechin-3-gallate on Esophageal Cancer. Molecules 24:5, pages 954.
Crossref
Shenoy K. Chandrakala, Reema Orison Lobo & Flora Olinda Dias. 2019. Nutrients in Beverages. Nutrients in Beverages 591 616 .
Anna Winiarska-Mieczan. (2018) Protective effect of tea against lead and cadmium-induced oxidative stress—a review. BioMetals 31:6, pages 909-926.
Crossref
Juan Ni, Xihan Guo, Han Wang, Tao Zhou & Xu Wang. (2018) Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells. Molecules 23:4, pages 788.
Crossref
P. SolversonJ. A. NovotnyT. Castonguay. 2017. Handbook of nutrition in heart health. Handbook of nutrition in heart health 415 441 .
Zhenghua Duan, Yanshuai Xing, Zhitong Feng, Huiyuan Zhang, Caixia Li, Zhiyuan Gong, Lei Wang & Hongwen Sun. (2017) Hepatotoxicity of benzotriazole and its effect on the cadmium induced toxicity in zebrafish Danio rerio. Environmental Pollution 224, pages 706-713.
Crossref
Weikun Li, Murat Yalcin, Qishan Lin, Mohammed-Salleh M. Ardawi & Shaker A. Mousa. (2017) Self-assembly of green tea catechin derivatives in nanoparticles for oral lycopene delivery. Journal of Controlled Release 248, pages 117-124.
Crossref
Maryam Rameshrad, Bibi Marjan Razavi & Hossein Hosseinzadeh. (2017) Protective effects of green tea and its main constituents against natural and chemical toxins: A comprehensive review. Food and Chemical Toxicology 100, pages 115-137.
Crossref
Xue Bing, Liu Xuelei, Dong Wanwei, Liang Linlang & Chen Keyan. (2017) EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF- κ B Signaling Pathway in Rats . Canadian Journal of Gastroenterology and Hepatology 2017, pages 1-9.
Crossref
Olga Krupkova, Stephen J. Ferguson & Karin Wuertz-Kozak. (2016) Stability of (−)-epigallocatechin gallate and its activity in liquid formulations and delivery systems. The Journal of Nutritional Biochemistry 37, pages 1-12.
Crossref
WEI LIU, MINGQING DONG, LIYAN BO, CONGCONG LI, QINGQING LIU, ZHICHAO LI & FAGUANG JIN. (2016) Epigallocatechin-3-gallate suppresses alveolar epithelial cell apoptosis in seawater aspiration-induced acute lung injury via inhibiting STAT1-caspase-3/p21 associated pathway. Molecular Medicine Reports 13:1, pages 829-836.
Crossref
Robert Domitrović & Iva Potočnjak. (2015) A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives. Archives of Toxicology 90:1, pages 39-79.
Crossref
Aida Salameh, Anne Einenkel, Lydia Kühne, Maria Grassl, Sandy von Salisch, Phillip Kiefer, Marcel Vollroth, Ingo Dähnert & Stefan Dhein. (2015) Hippocampal Neuroprotection by Minocycline and Epigallo-Catechin-3-Gallate Against Cardiopulmonary Bypass-Associated Injury. Brain Pathology 25:6, pages 733-742.
Crossref
JIANHUA YANG, YAO YAN, HUIBIN LIU, JIANHUA WANG & JUNPING HU. (2015) Protective effects of acteoside against X-ray-induced damage in human skin fibroblasts. Molecular Medicine Reports 12:2, pages 2301-2306.
Crossref
Samuel Legeay, Marion Rodier, Laetitia Fillon, Sébastien Faure & Nicolas Clere. (2015) Epigallocatechin Gallate: A Review of Its Beneficial Properties to Prevent Metabolic Syndrome. Nutrients 7:7, pages 5443-5468.
Crossref
Yanqiu Wang, Na Liu, Xiaohui Bian, Guangping Sun, Feng Du, Bowen Wang, Xuesong Su & Detian Li. (2015) Epigallocatechin-3-gallate reduces tubular cell apoptosis in mice with ureteral obstruction. Journal of Surgical Research 197:1, pages 145-154.
Crossref
Hanxi Zhao, Peng Xie, Xiaolin Li, Wanqi Zhu, Xindong Sun, Xiaorong Sun, Xiaoting Chen, Ligang Xing & Jinming Yu. (2015) A prospective phase II trial of EGCG in treatment of acute radiation-induced esophagitis for stage III lung cancer. Radiotherapy and Oncology 114:3, pages 351-356.
Crossref
Hua Xie, Jianqin Sun, Yanqiu Chen, Min Zong, Shijie Li & Yan Wang. (2015) EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway. Oxidative Medicine and Cellular Longevity 2015, pages 1-10.
Crossref
Chi-Wu Chang, Yi-Hsien Hsieh, Wei-En Yang, Shun-Fa Yang, Yueqin Chen & Dan-Ning Hu. (2014) Epigallocatechingallate Inhibits Migration of Human Uveal Melanoma Cells via Downregulation of Matrix Metalloproteinase-2 Activity and ERK1/2 Pathway. BioMed Research International 2014, pages 1-9.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.