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Research Article

The leaf extract of Spondias mombin L. displays an anti-inflammatory effect and suppresses inducible formation of tumor necrosis factor-α and nitric oxide (NO)

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Pages 10-16 | Received 24 Aug 2010, Accepted 09 Oct 2010, Published online: 24 Jan 2011

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Shahrzad Zamani Taghizadeh Rabe, Seyed Hadi Mousavi, Nafise Tabasi, Maryam Rastin, Shahin Zamani Taghizadeh Rabe, Zahra Siadat & Mahmoud Mahmoudi. (2014) Rose Bengal suppresses gastric cancer cell proliferation via apoptosis and inhibits nitric oxide formation in macrophages. Journal of Immunotoxicology 11:4, pages 367-375.
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Wioletta Ratajczak-Wrona, Ewa Jablonska, Marzena Garley, Jakub Jablonski, Piotr Radziwon, Agnieszka Iwaniuk & Kamil Grubczak. (2014) PI3K-Akt/PKB signaling pathway in neutrophils and mononuclear cells exposed to N-nitrosodimethylamine. Journal of Immunotoxicology 11:3, pages 231-237.
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Festus Basden C. Okoye, Chukwuemeka S. Nworu, Peter A. Akah, Charles O. Esimone, Abdessamad Debbab & Peter Proksch. (2013) Inhibition of inflammatory mediators and reactive oxygen and nitrogen species by some depsidones and diaryl ether derivatives isolated from Corynespora cassiicola, an endophytic fungus of Gongronema latifolium leaves. Immunopharmacology and Immunotoxicology 35:6, pages 662-668.
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Articles from other publishers (19)

Olalekan Bukunmi Ogunro, Barnabas Oluwatomide Oyeyinka, Gideon Ampoma Gyebi & Gaber El-Saber Batiha. (2023) Nutritional benefits, ethnomedicinal uses, phytochemistry, pharmacological properties and toxicity of Spondias mombin Linn: a comprehensive review . Journal of Pharmacy and Pharmacology 75:2, pages 162-226.
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Njideka Ifeoma Ani, Kenneth Obinna Okolo & Raymond Ogbonna Offiah. (2023) Evaluation of antibacterial, antioxidant, and anti-inflammatory properties of GC/MS characterized methanol leaf extract of Terminalia superba (Combretaceae, Engl. & Diels). Future Journal of Pharmaceutical Sciences 9:1.
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Ayokunle O. Ademosun, Temitope V. Popoola, Ganiyu Oboh & Olamide W. Fasakin. (2022) Parquetina nigrescens and Spondias mombin protects against neurochemical alterations in the scopolamine model of cognitive dysfunction . Journal of Food Biochemistry 46:11.
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Gertrude Adomaa Asante Ampadu, Jehoshaphat Oppong Mensah, Godfred Darko & Lawrence Sheringham Borquaye. (2022) Essential Oils from the Fruits and Leaves of Spondias mombin Linn.: Chemical Composition, Biological Activity, and Molecular Docking Study. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-14.
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Akwasi Boadu, Clement Agoni, Rajshekhar Karpoormath, Mahmoud Soliman & Manimbulu Nlooto. (2022) Repurposing antiviral phytochemicals from the leaf extracts of Spondias mombin (Linn) towards the identification of potential SARSCOV-2 inhibitors. Scientific Reports 12:1.
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Abidemi J. Akindele, Abimbola Sowemimo, Foluso O. Agunbiade, Margaret O. Sofidiya, Olufunsho Awodele, Omobolanle Ade-Ademilua, Ifeoma Orabueze, Ismail O. Ishola, Christianah I. Ayolabi, Olumuyiwa B. Salu, Moshood O. Akinleye & Ibrahim A. Oreagba. (2022) Bioprospecting for Anti-COVID-19 Interventions From African Medicinal Plants: A Review. Natural Product Communications 17:5, pages 1934578X2210969.
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Ana Sofia Ferreira, Catarina Macedo, Ana Margarida Silva, Cristina Delerue-Matos, Paulo Costa & Francisca Rodrigues. (2022) Natural Products for the Prevention and Treatment of Oral Mucositis—A Review. International Journal of Molecular Sciences 23:8, pages 4385.
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Hina Fatima, Muhammad Shahid, Chris Pruitt, Meredith A. Pung, Paul J. Mills, Muhammad Riaz & Rizwan Ashraf. (2022) Chemical Fingerprinting, Antioxidant, and Anti-Inflammatory Potential of Hydroethanolic Extract of Trigonella foenum-graecum. Antioxidants 11:2, pages 364.
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Olubukola Benedicta Ojo, Grace Boluwatife Olagunju, Abigail Oladunni Olajide, Muyiwa Emmanuel Jegede, Adewale Stephen Fakorede, Olamide Olajusi Crown, Mary Tolulope Olaleye & Afolabi Clement Akinmoladun. (2022) Spondias mombin leaf extract ameliorates cerebral ischemia/reperfusion-induced cardiohepatorenal oxidative stress in rats. Phytomedicine Plus 2:1, pages 100196.
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Solomon N. Ijioma, Okezie Emmanuel, Chidi I. Nosiri & Eziuche A. Ugbogu. (2021) Evaluation of toxicity profile and pharmacological potentials of Aju Mbaise polyherbal extract in rats. Scientific African 11, pages e00681.
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Glaucia Dal Santo, Bruno Oliveira de Veras, Eduardo Rico, Jacir Dal Magro, Jotele Fontana Agostini, Leucio Duarte Vieira, Jean Felipe Fossá Calisto, Ricieri Mocelin, Vitória de Sá Fonseca & Almir Gonçalves Wanderley. (2021) Hexane extract from SpoSndias mombin L. (Anacardiaceae) prevents behavioral and oxidative status changes on model of Parkinson's disease in zebrafish. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 241, pages 108953.
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Mayur Porwal, Sandeep K. Gautam, Najam A. Khan & Kamal K. Maheshwari. (2021) Evaluation of Toxicity and Antihyperlipidemic Activity of Spondias Mombin l. Leaves Methanolic Extract in Laboratory Rats. Cardiovascular & Hematological Disorders-Drug Targets 20:4, pages 289-296.
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Mayra Sousa Gomes, Ruthineia Diógenes Alves Uchoa Lins, Silvana Maria Zucolotto Langassner, Éricka Janine Dantas da Silveira, Thais Gomes de Carvalho, Maria Luiza Diniz de Sousa Lopes, Lorena de Souza Araújo, Caroline Addison Carvalho Xavier de Medeiros, Renata Ferreira de Carvalho Leitão, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Junior & Aurigena Antunes de Araújo. (2020) Anti-inflammatory and antioxidant activity of hydroethanolic extract of Spondias mombin leaf in an oral mucositis experimental model. Archives of Oral Biology 111, pages 104664.
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Adeoye Adeniyi, Alex Asase, Patrick K. Ekpe, Bismark K. Asitoakor, Anthony Adu-Gyamfi & Prosper Y. Avekor. (2018) Ethnobotanical study of medicinal plants from Ghana; confirmation of ethnobotanical uses, and review of biological and toxicological studies on medicinal plants used in Apra Hills Sacred Grove. Journal of Herbal Medicine 14, pages 76-87.
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Lucky L. Nwidu, Ekramy Elmorsy, Yibala I. Oboma & Wayne G. Carter. (2018) Hepatoprotective and antioxidant activities of Spondias mombin leaf and stem extracts against carbon tetrachloride-induced hepatotoxicity. Journal of Taibah University Medical Sciences 13:3, pages 262-271.
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Samara Alves Brito, Cynthia Layse Ferreira de Almeida, Temístocles Italo de Santana, Alisson Rodrigo da Silva Oliveira, Jéssica Carla Bezerra do Nascimento Figueiredo, Isis Torres Souza, Lécio Leone de Almeida, Márcia Vanusa da Silva, Augusto Santos Borges, Jonathan Wagner de Medeiros, Jacinto da Costa Silva Neto, Rita de Cássia Ribeiro Gonçalves, Rodrigo Rezende Kitagawa, Antônio Euzébio Goulart Sant'Ana, Larissa Araújo Rolim, Irwin Rose Alencar de Menezes, Teresinha Gonçalves da Silva, Germana Freire Rocha Caldas & Almir Gonçalves Wanderley. (2018) Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L. . Oxidative Medicine and Cellular Longevity 2018, pages 1-20.
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Guillaume Odonne, Emeline Houël, Geneviève Bourdy & Didier Stien. (2017) Treating leishmaniasis in Amazonia: A review of ethnomedicinal concepts and pharmaco-chemical analysis of traditional treatments to inspire modern phytotherapies. Journal of Ethnopharmacology 199, pages 211-230.
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Emerson Michell da Silva Siqueira, Juliana Félix-Silva, Lorena Maria Lima de Araújo, Julia Morais Fernandes, Bárbara Cabral, Jacyra Antunes dos Santos Gomes, Alan de Araújo Roque, José Carlos Tomaz, Norberto Peporine Lopes, Matheus de Freitas Fernandes-Pedrosa, Raquel Brandt Giordani & Silvana Maria Zucolotto. (2016) Spondias tuberosa (Anacardiaceae) leaves: profiling phenolic compounds by HPLC-DAD and LC-MS/MS and in vivo anti-inflammatory activity . Biomedical Chromatography 30:10, pages 1656-1665.
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Bárbara Cabral, Emerson M.S. Siqueira, Mariana A.O. Bitencourt, Maíra C.J.S. Lima, Ana K. Lima, Caroline F. Ortmann, Vitor C. Chaves, Matheus F. Fernandes-Pedrosa, Hugo A.O. Rocha, Katia C. Scortecci, Flávio H. Reginatto, Raquel B. Giordani & Silvana M. Zucolotto. (2016) Phytochemical study and anti-inflammatory and antioxidant potential of Spondias mombin leaves. Revista Brasileira de Farmacognosia 26:3, pages 304-311.
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