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Postgraduate Medicine Volume 125, 2013 - Issue 5
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Clinical Features

Lower-Dose Diclofenac Submicron Particle Capsules Provide Early and Sustained Acute Patient Pain Relief in a Phase 3 Study

Allan Gibofsky Professor of Medicine and Public Health, Weill Medical College of Cornell University, Attending Rheumatologist, Hospital for Special Surgery, New York, NY
, MD, FACR, JD,
Stephen Silberstein Director, Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA
, MD,
Charles Argoff Pain Medicine Specialist, Albany Medical Center; AMC Neurology Group, Albany NY
, MD,
Stephen Daniels Premier Research Group Limited, Philadelphia, PA
, DO,
Steve Jensen Senior Vice President, Regulatory Affairs and Quality, Iroko Pharmaceuticals, LLC, Philadelphia, PA
&
Clarence L. Young Chief Medical Officer, Iroko Pharmaceuticals, LLC, Philadelphia, PACorrespondence[email protected]
, MD
Pages 130-138 | Published online: 13 Mar 2015

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Kay Brune & Paola Patrignani. (2015) New insights into the use of currently available non-steroidal anti-inflammatory drugs. Journal of Pain Research 8, pages 105-118.
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Jay L Goldstein & Byron Cryer. (2015) Gastrointestinal injury associated with NSAID use: a case study and review of risk factors and preventative strategies. Drug, Healthcare and Patient Safety 7, pages 31-41.
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Allan Gibofsky, Roy Altman, Stephen Daniels, Olaolu Imasogie & Clarence Young. (2015) Low-dose SoluMatrix diclofenac: a review of safety across two Phase III studies in patients with acute and osteoarthritis pain. Expert Opinion on Drug Safety 14:8, pages 1327-1339.
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Satomi Onoue, Shizuo Yamada & Hak-Kim Chan. (2014) Nanodrugs: pharmacokinetics and safety. International Journal of Nanomedicine 9, pages 1025-1037.
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David A. Provenzano & Eugene R. Viscusi. (2014) Rethinking the role of opioids in the outpatient management of chronic nonmalignant pain. Current Medical Research and Opinion 30:10, pages 2051-2062.
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Allan Gibofsky, Marc C. Hochberg, Mark J. Jaros & Clarence L. Young. (2014) Efficacy and safety of low-dose submicron diclofenac for the treatment of osteoarthritis pain: a 12 week, phase 3 study. Current Medical Research and Opinion 30:9, pages 1883-1893.
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Srinivas Nalamachu, Joseph V Pergolizzi, Robert B Raffa, Dhanunjaya R Lakkireddy & Robert Taylor$suffix/text()$suffix/text(). (2014) Drug–drug interaction between NSAIDS and low-dose aspirin: a focus on cardiovascular and GI toxicity. Expert Opinion on Drug Safety 13:7, pages 903-917.
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Articles from other publishers (12)

Chiara Delbaldo, Matilde Tschon, Lucia Martini, Milena Fini & Giorgia Codispoti. (2022) Benefits of Applying Nanotechnologies to Hydrogels in Efficacy Tests in Osteoarthritis Models—A Systematic Review of Preclinical Studies. International Journal of Molecular Sciences 23:15, pages 8236.
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Abhijit Nair, Poornachand Anne, KodisharapuP Kumar & SrinivasaS P. Mantha. (2022) Nanotechnology in pain medicine: What is new?. Journal of Anaesthesiology Clinical Pharmacology 38:2, pages 326.
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Neil K. Singla, Diana S. Meske & Paul J. Desjardins. (2017) Exploring the Interplay between Rescue Drugs, Data Imputation, and Study Outcomes: Conceptual Review and Qualitative Analysis of an Acute Pain Data Set. Pain and Therapy 6:2, pages 165-175.
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Deirdre Mladsi, Naoko Ronquest, Dawn Odom, LaStella Miles & Kenneth Saag. (2016) Cost-effectiveness of Low-dose Submicron Diclofenac Compared With Generic Diclofenac. Clinical Therapeutics 38:11, pages 2418-2429.
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Charles Argoff, Bill McCarberg, Jeff Gudin, Srinivas Nalamachu & Clarence Young. (2016) SoluMatrix ® Diclofenac: Sustained Opioid-Sparing Effects in a Phase 3 Study in Patients with Postoperative Pain . Pain Medicine 17:10, pages 1933-1941.
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Joseph V PergolizziJrJr, Robert B Raffa, Srinivas Nalamachu & Robert TaylorJrJr. (2016) Evolution to low-dose NSAID therapy. Pain Management 6:2, pages 175-189.
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I. Gil-Aldea & J.R. Azanza Perea. (2016) Complicaciones gástricas de tratamientos farmacológicos. Medicine - Programa de Formación Médica Continuada Acreditado 12:3, pages 137-142.
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Bill H. McCarberg & Byron Cryer. (2015) Evolving Therapeutic Strategies to Improve Nonsteroidal Anti-inflammatory Drug Safety. American Journal of Therapeutics 22:6, pages e167-e178.
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Arthur Lipman & Lynn Webster. (2015) The Economic Impact of Opioid Use in the Management of Chronic Nonmalignant Pain. Journal of Managed Care & Specialty Pharmacy 21:10, pages 891-899.
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Roy Altman, Bill Bosch, Kay Brune, Paola Patrignani & Clarence Young. (2015) Advances in NSAID Development: Evolution of Diclofenac Products Using Pharmaceutical Technology. Drugs 75:8, pages 859-877.
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Paul J. Desjardins, Kemi Olugemo, Daniel Solorio & Clarence L. Young. (2015) Pharmacokinetic Properties and Tolerability of Low-dose SoluMatrix Diclofenac. Clinical Therapeutics 37:2, pages 448-461.
Crossref
Esther Pogatzki-Zahn, Chandani Chandrasena & Stephan A. Schug. (2014) Nonopioid analgesics for postoperative pain management. Current Opinion in Anaesthesiology 27:5, pages 513-519.
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