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JOURNAL CLUB

BET bromodomain inhibitors—A novel epigenetic approach in castration-resistant prostate cancer

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Pages 1583-1585 | Received 19 Aug 2014, Accepted 01 Sep 2014, Published online: 23 Dec 2014

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Suzanne Ackloo, Peter J. Brown & Susanne Müller. (2017) Chemical probes targeting epigenetic proteins: Applications beyond oncology. Epigenetics 12:5, pages 378-400.
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Chao Wang, Yujing Zhang, Yudong Wu & Dongming Xing. (2021) Developments of CRBN-based PROTACs as potential therapeutic agents. European Journal of Medicinal Chemistry 225, pages 113749.
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Ai Liu, Dianxia Fan & Yanping Wang. (2018) The BET bromodomain inhibitor i-BET151 impairs ovarian cancer metastasis and improves antitumor immunity. Cell and Tissue Research 374:3, pages 577-585.
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Young Hun Kim, Minsung Kim, Miyoun Yoo, Ji Eun Kim, Heung Kyoung Lee, Jung-Nyoung Heo, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Chang-Soo Yun, Sung Woong Moon, Hye Kyung Chang, Chul-Woong Chung, Suhkneung Pyo, Sang Un Choi & Chi Hoon Park. (2018) A natural compound, aristoyagonine, is identified as a potent bromodomain inhibitor by mid-throughput screening. Biochemical and Biophysical Research Communications 503:2, pages 882-887.
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Bin Chen, Jing Yu, Qianqian Wang, Yuanyuan Zhao, Li Sun, Changgen Xu, Xiangdong Zhao, Bo Shen, Mei Wang, Wenrong Xu & Wei Zhu. (2018) Human Bone Marrow Mesenchymal Stem Cells Promote Gastric Cancer Growth via Regulating c-Myc . Stem Cells International 2018, pages 1-11.
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Simon Baumgart & Bernard Haendler. (2017) Exploiting Epigenetic Alterations in Prostate Cancer. International Journal of Molecular Sciences 18:5, pages 1017.
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Kazuki Mochizuki, Natsuyo Hariya, Kazue Honma & Toshinao Goda. 2017. Handbook of Nutrition, Diet, and Epigenetics. Handbook of Nutrition, Diet, and Epigenetics 1 15 .
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Limei Wang, Xiuyin Wu, Ping Huang, Zhijun Lv, Yuping Qi, Xiujuan Wei, Pishan Yang & Fenghe Zhang. (2016) JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma. Oncology Reports.
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Mukesh Verma. (2016) Genome-wide association studies and epigenome-wide association studies go together in cancer control. Future Oncology 12:13, pages 1645-1664.
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Aaron M. Udager, Angelo M. DeMarzo, Yang Shi, Jessica L. Hicks, Xuhong Cao, Javed Siddiqui, Hui Jiang, Arul M. Chinnaiyan & Rohit Mehra. (2016) Concurrent nuclear ERG and MYC protein overexpression defines a subset of locally advanced prostate cancer: Potential opportunities for synergistic targeted therapeutics. The Prostate 76:9, pages 845-853.
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Camille Jacques, François Lamoureux, Marc Baud’huin, Lidia Rodriguez Calleja, Thibaut Quillard, Jérôme Amiaud, Franck Tirode, Françoise Rédini, James E. Bradner, Dominique Heymann & Benjamin Ory. (2016) Targeting the epigenetic readers in Ewing Sarcoma inhibits the oncogenic transcription factor EWS/Fli1. Oncotarget 7:17, pages 24125-24140.
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Ester Fernandez-Salas, Shaomeng Wang & Arul M Chinnaiyan. (2016) Role of BET proteins in castration-resistant prostate cancer. Drug Discovery Today: Technologies 19, pages 29-38.
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