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Cancer Biology & Therapy Volume 13, 2012 - Issue 9
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Research Paper

Mesenchymal stem cells in mammary adipose tissue stimulate progression of breast cancer resembling the basal-type

Min Zhao Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA
,
Patrick C. Sachs LifeNet Health; Regenerative Medicine Institute; Virginia Beach, VA USA
,
Xu Wang Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA
,
Catherine I. Dumur Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Va Usa
,
Michael O. Idowu Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Virginia USA
,
Valentina Robila Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA
,
Michael P. Francis LifeNet Health; Regenerative Medicine Institute; Virginia Beach, VA USA
,
Joy Ware Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Virginia USA
,
Matthew Beckman Deparment of Pharmacology and Toxicology; Virginia Commonwealth University; Richmond, Virginia USA
,
Aylin Rizki Department of Radiation Oncology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Virginia USA
,
Shawn E. Holt Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA; Department of Human and Molecular Genetics; Virginia Commonwealth University; Richmond, Virginia USA; Deparment of Pharmacology and Toxicology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Virginia USA; Department of Biology; Virginia State University; Petersburg, VA USA
&
Lynne W. Elmore Department of Pathology; Virginia Commonwealth University; Richmond, Virginia USA; Massey Cancer Center; Virginia Commonwealth University; Richmond, Virginia USA; The School of Nursing Center for Biobehavioral Research; Virginia Commonwealth University; Richmond, Virginia USACorrespondence[email protected]
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Pages 782-792 | Received 13 Feb 2012, Accepted 29 Apr 2012, Published online: 06 Jun 2012

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Vanessa Benham, Debrup Chakraborty, Blair Bullard & Jamie J. Bernard. (2018) A role for FGF2 in visceral adiposity-associated mammary epithelial transformation. Adipocyte 7:2, pages 113-120.
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Anqi Wu, Qiaoxiang Dong, Hui Gao, Yuanshuo Shi, Yuanhong Chen, Fuchuang Zhang, Abhik Bandyopadhyay, Danhan Wang, Karla M. Gorena, Changjiang Huang, Suzette Tardif, Peter W. Nathanielsz & Lu-Zhe Sun. (2016) Characterization of mammary epithelial stem/progenitor cells and their changes with aging in common marmosets. Scientific Reports 6:1.
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Crossref
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Crossref
Felicite K. Noubissi, Ty Harkness, Caroline M. Alexander & Brenda M. Ogle. (2017) Apoptosis‐induced cancer cell fusion: a mechanism of breast cancer metastasis. The FASEB Journal 29:9, pages 4036-4045.
Crossref
Fayaz Malik, Hasan Korkaya, Shawn G. Clouthier & Max S. Wicha. 2015. Principles of Stem Cell Biology and Cancer. Principles of Stem Cell Biology and Cancer 123 143 .
Kyle E. Freese, Lauren Kokai, Robert P. Edwards, Brian J. Philips, M. Aamir Sheikh, Joseph Kelley, John Comerci, Kacey G. Marra, J. Peter Rubin & Faina Linkov. (2015) Adipose-Derived Stems Cells and Their Role in Human Cancer Development, Growth, Progression, and Metastasis: A Systematic Review. Cancer Research 75:7, pages 1161-1168.
Crossref
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Crossref
Hui-Ying Yang, Rong-Mei Qu, Xiao-Shan Lin, Tong-Xin Liu, Quan-Quan Sun, Chun Yang, Xiao-Hong Li, Wei Lu, Xiao-Fang Hu, Jing-Xing Dai & Lin Yuan. (2015) IGF-1 from Adipose-Derived Mesenchymal Stem Cells Promotes Radioresistance of Breast Cancer Cells. Asian Pacific Journal of Cancer Prevention 15:23, pages 10115-10119.
Crossref
Riccardo Schweizer, Wakako Tsuji, Vijay S. Gorantla, Kacey G. Marra, J. Peter Rubin & Jan A. Plock. (2015) The Role of Adipose-Derived Stem Cells in Breast Cancer Progression and Metastasis. Stem Cells International 2015, pages 1-17.
Crossref
Melis Olcum & Engin Ozcivici. (2014) Daily application of low magnitude mechanical stimulus inhibits the growth of MDA-MB-231 breast cancer cells in vitro. Cancer Cell International 14:1.
Crossref
Michael Alperovich, Z-Hye Lee, Paul L. Friedlander, Brian G. Rowan, Jeffrey M. Gimble & Ernest S. Chiu. (2014) Adipose Stem Cell Therapy in Cancer Reconstruction. Annals of Plastic Surgery 73:Supplement 1, pages S104-S107.
Crossref
Vincenzo Eterno, Alberto Zambelli, Lorenzo Pavesi, Laura Villani, Vittorio Zanini, Gianfranco Petrolo, Stefania Manera, Antonella Tuscano & Angela Amato. (2013) Adipose-derived mesenchymal stem cells (ASCs) may favour breast cancer recurrence via HGF/c-Met signaling. Oncotarget 5:3, pages 613-633.
Crossref
Drenka Trivanović, Srdjan Nikolić, Jelena Krstić, Aleksandra Jauković, Slavko Mojsilović, Vesna Ilić, Ivana Okić‐Djordjević, Juan Francisco Santibanez, Gordana Jovčić & Diana Bugarski. (2013) Characteristics of human adipose mesenchymal stem cells isolated from healthy and cancer affected people and their interactions with human breast cancer cell line M CF ‐7 in vitro . Cell Biology International 38:2, pages 254-265.
Crossref
Dar-Ren Chen, Dah-Yuu Lu, Hui-Yi Lin & Wei-Lan Yeh. (2014) Mesenchymal Stem Cell-Induced Doxorubicin Resistance in Triple Negative Breast Cancer. BioMed Research International 2014, pages 1-10.
Crossref
Ludovic Zimmerlin, Tea Soon Park, Elias T. Zambidis, Vera S. Donnenberg & Albert D. Donnenberg. (2013) Mesenchymal stem cell secretome and regenerative therapy after cancer. Biochimie 95:12, pages 2235-2245.
Crossref
Stefania Orecchioni, Giuliana Gregato, Ines Martin-Padura, Francesca Reggiani, Paola Braidotti, Patrizia Mancuso, Angelica Calleri, Jessica Quarna, Paola Marighetti, Chiara Aldeni, Giancarlo Pruneri, Stefano Martella, Andrea Manconi, Jean-Yves Petit, Mario Rietjens & Francesco Bertolini. (2013) Complementary Populations of Human Adipose CD34+ Progenitor Cells Promote Growth, Angiogenesis, and Metastasis of Breast Cancer. Cancer Research 73:19, pages 5880-5891.
Crossref
Timothy Marsh, Kristian Pietras & Sandra S. McAllister. (2013) Fibroblasts as architects of cancer pathogenesis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:7, pages 1070-1078.
Crossref
Liyang Zhang, Juanjuan Xiang & Guiyuan Li. (2013) The uncertain role of unmodified mesenchymal stem cells in tumor progression: what master switch?. Stem Cell Research & Therapy 4:2.
Crossref
Melissa Marie Alegre, McKay Hovis Knowles, Richard A. Robison & Kim Leslie O'Neill. (2013) Mechanics behind Breast Cancer Prevention - Focus on Obesity, Exercise and Dietary Fat. Asian Pacific Journal of Cancer Prevention 14:4, pages 2207-2212.
Crossref
Mei Yang, Lingling Sheng, Tian R. Zhang & Qingfeng Li. (2013) Stem Cell Therapy for Lower Extremity Diabetic Ulcers: Where Do We Stand?. BioMed Research International 2013, pages 1-8.
Crossref

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