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Epigenetics Volume 7, 2012 - Issue 12
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Research Paper

Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles

Meena Kanduri Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine; Sahlgrenska University Hospital; Gothenburg, Sweden
,
Millaray Marincevic Department of Immunology, Genetics and Pathology; Science for Life Laboratory; Uppsala University; Uppsala, Sweden
,
Anna M. Halldórsdóttir Department of Immunology, Genetics and Pathology; Science for Life Laboratory; Uppsala University; Uppsala, Sweden
,
Larry Mansouri Department of Immunology, Genetics and Pathology; Science for Life Laboratory; Uppsala University; Uppsala, Sweden
,
Katarina Junevik Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine; Sahlgrenska University Hospital; Gothenburg, Sweden
,
Stavroula Ntoufa Hematology Department and HCT Unit; G. Papanicolaou Hospital; Thessaloniki, Greece
,
Hanna Göransson Kultima Department of Medical Sciences; Science for Life Laboratory; Uppsala University; Uppsala, Sweden
,
Anders Isaksson Department of Medical Sciences; Science for Life Laboratory; Uppsala University; Uppsala, Sweden
,
Gunnar Juliusson Lund Strategic Research Center for Stem Cell Biology and Cell Therapy; Hematology and Transplantation; Lund University; Lund, Sweden
,
Per-Ola Andersson Section of Hematology and Coagulation; Department of Internal Medicine; Sahlgrenska University Hospital; Gothenburg, Sweden
,
Hans Ehrencrona Department of Clinical Genetics; Lund University Hospital; Lund, Sweden
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Kostas Stamatopoulos Hematology Department and HCT Unit; G. Papanicolaou Hospital; Thessaloniki, Greece; Institute of Applied Biosciences; Center for Research and Technology; Thessaloniki, Greece
&
Richard Rosenquist Department of Immunology, Genetics and Pathology; Science for Life Laboratory; Uppsala University; Uppsala, SwedenCorrespondence[email protected]
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Pages 1435-1442 | Published online: 15 Nov 2012

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Pradeep Kumar Kopparapu, Sujata Bhoi, Larry Mansouri, Laleh S. Arabanian, Karla Plevova, Sarka Pospisilova, Agata M. Wasik, Giorgio Alberto Croci, Birgitta Sander, Marco Paulli, Richard Rosenquist & Meena Kanduri. (2016) Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression. Epigenetics 11:5, pages 335-343.
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Andreas Agathangelidis, Anna Vardi, Panagiotis Baliakas & Kostas Stamatopoulos. (2014) Stereotyped B-cell receptors in chronic lymphocytic leukemia. Leukemia & Lymphoma 55:10, pages 2252-2261.
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Stefan Deneberg, Meena Kanduri, Dina Ali, Sofia Bengtzen, Mohsen Karimi, Ying Qu, Eva Kimby, Larry Mansouri, Richard Rosenquist, Andreas Lennartsson & Sören Lehmann. (2014) microRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemia. Epigenetics 9:6, pages 910-917.
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Nicola Cahill & Richard Rosenquist. (2013) Uncovering the DNA methylome in chronic lymphocytic leukemia. Epigenetics 8:2, pages 138-148.
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B. V. Biderman & A. B. Sudarikov. (2023) Immunoglobulin genes and stereotyped antigenic receptors in chronic lymphocytic leukemia and other lymphoproliferative diseases. Russian journal of hematology and transfusiology 68:1, pages 70-79.
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Bella V. Biderman, Ekaterina B. Likold, Nataliya A. Severina, Tatiana N. Obukhova & Andrey B. Sudarikov. (2023) Genetic Lesions in Russian CLL Patients with the Most Common Stereotyped Antigen Receptors. Genes 14:2, pages 532.
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Alessandra Rovida, Cristina Maccalli, Lydia Scarfò, Paolo Dellabona, Kostas Stamatopoulos & Paolo Ghia. (2021) Exploiting B-cell Receptor Stereotypy to Design Tailored Immunotherapy in Chronic Lymphocytic Leukemia. Clinical Cancer Research 27:3, pages 729-739.
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Katerina Gemenetzi, Andreas Agathangelidis, Laura Zaragoza-Infante, Electra Sofou, Maria Papaioannou, Anastasia Chatzidimitriou & Kostas Stamatopoulos. (2020) B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making. Frontiers in Oncology 10.
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Miyoung Kim, Eunyup Lee, Dae Young Zang, Hyo Jung Kim, Ho Young Kim, Boram Han, Han-Sung Kim, Hee Jung Kang, Seungwoo Hwang & Young Kyung Lee. (2020) Novel genes exhibiting DNA methylation alterations in Korean patients with chronic lymphocytic leukaemia: a methyl-CpG-binding domain sequencing study. Scientific Reports 10:1.
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Maria Tsagiopoulou, Nikos Papakonstantinou, Theodoros Moysiadis, Larry Mansouri, Viktor Ljungström, Martí Duran-Ferrer, Andigoni Malousi, Ana C. Queirós, Karla Plevova, Sujata Bhoi, Panagoula Kollia, David Oscier, Achilles Anagnostopoulos, Livio Trentin, Matthias Ritgen, Sarka Pospisilova, Niki Stavroyianni, Paolo Ghia, Jose I. Martin-Subero, Christiane Pott, Richard Rosenquist & Kostas Stamatopoulos. (2019) DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy. Clinical Epigenetics 11:1.
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Sahar Safaei, Behzad Baradaran, Majid Farshdousti Hagh, Mohammad Reza Alivand, Mehdi Talebi, Tohid Gharibi & Saeed Solali. (2018) Double sword role of EZH2 in leukemia. Biomedicine & Pharmacotherapy 98, pages 626-635.
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Prabhjot KaurPrabhjot Kaur. 2018. Chronic Lymphocytic Leukemia. Chronic Lymphocytic Leukemia 111 132 .
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Pradeep Kumar Kopparapu, Mohammad Hamdy Abdelrazak Morsy, Chandrasekhar Kanduri & Meena Kanduri. (2017) Gene-body hypermethylation controlled cryptic promoter and miR26A1-dependent EZH2 regulation of TET1 gene activity in chronic lymphocytic leukemia. Oncotarget 8:44, pages 77595-77608.
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K Stamatopoulos, A Agathangelidis, R Rosenquist & P Ghia. (2016) Antigen receptor stereotypy in chronic lymphocytic leukemia. Leukemia 31:2, pages 282-291.
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Santhilal Subhash, Per-Ola Andersson, Subazini Thankaswamy Kosalai, Chandrasekhar Kanduri & Meena Kanduri. (2016) Global DNA methylation profiling reveals new insights into epigenetically deregulated protein coding and long noncoding RNAs in CLL. Clinical Epigenetics 8:1.
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Marie de Charette, Aurélien Marabelle & Roch Houot. (2016) Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy?. European Journal of Cancer 68, pages 134-147.
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Zadie Davis, Francesco Forconi, Anton Parker, Anne Gardiner, Peter Thomas, Daniel Catovsky, Matthew Rose-Zerilli, Jonathan C Strefford & David Oscier. (2016) The outcome of Chronic lymphocytic leukaemia patients with 97% IGHV gene identity to germline is distinct from cases with <97% identity and similar to those with 98% identity . British Journal of Haematology 173:1, pages 127-136.
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Lesley-Ann Sutton & Richard Rosenquist. (2015) The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemia. Seminars in Cancer Biology 34, pages 22-35.
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J C Strefford, L-A Sutton, P Baliakas, A Agathangelidis, J Malčíková, K Plevova, L Scarfó, Z Davis, E Stalika, D Cortese, N Cahill, L B Pedersen, P F di Celle, T Tzenou, C Geisler, P Panagiotidis, A W Langerak, N Chiorazzi, S Pospisilova, D Oscier, F Davi, C Belessi, L Mansouri, P Ghia, K Stamatopoulos & R Rosenquist. (2013) Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2. Leukemia 27:11, pages 2196-2199.
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José I. Martín-Subero, Carlos López-Otín & Elías Campo. (2013) Genetic and epigenetic basis of chronic lymphocytic leukemia. Current Opinion in Hematology 20:4, pages 362-368.
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