Advanced search
Publication Cover
Human Vaccines & Immunotherapeutics Volume 9, 2013 - Issue 7: Special Focus: VR6 Conference
Submit an article Journal homepage
1,854
Views
21
CrossRef citations to date
0
Altmetric
Special Focus Research Paper

Universal H1N1 influenza vaccine development

Identification of consensus class II hemagglutinin and neuraminidase epitopes derived from strains circulating between 1980 and 2011

Leonard Moise EpiVax, Inc.; Providence, RI USA; Institute for Immunology and Informatics; University of Rhode Island; Providence, RI USA
,
Frances Terry EpiVax, Inc.; Providence, RI USA
,
Matthew Ardito EpiVax, Inc.; Providence, RI USA
,
Ryan Tassone EpiVax, Inc.; Providence, RI USA
,
Howard Latimer EpiVax, Inc.; Providence, RI USA
,
Christine Boyle EpiVax, Inc.; Providence, RI USA
,
William D. Martin EpiVax, Inc.; Providence, RI USA
&
Anne S. De Groot EpiVax, Inc.; Providence, RI USA; Institute for Immunology and Informatics; University of Rhode Island; Providence, RI USACorrespondence[email protected]
 show all
Pages 1598-1607 | Received 19 Jun 2013, Accepted 30 Jun 2013, Published online: 11 Jul 2013

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Rui Liu, Leonard Moise, Ryan Tassone, Andres H Gutierrez, Frances E Terry, Kotou Sangare, Matthew T Ardito, William D Martin & Anne S De Groot. (2015) H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance. Human Vaccines & Immunotherapeutics 11:9, pages 2241-2252.
Read now
Wendy M C Shattuck, Megan C Dyer, Joe Desrosiers, Loren D Fast, Frances E Terry, William D Martin, Leonard Moise, Anne S De Groot & Thomas N Mather. (2014) Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice. Human Vaccines & Immunotherapeutics 10:10, pages 3048-3059.
Read now
Anne S De Groot, Lenny Moise, Rui Liu, Andres H Gutierrez, Frances Terry, Ousmane A Koita, Ted M Ross & William Martin. (2014) Cross-conservation of T-cell epitopes. Human Vaccines & Immunotherapeutics 10:2, pages 256-262.
Read now
Leonard Moise, Ryan Tassone, Howard Latimer, Frances Terry, Lauren Levitz, John P Haran, Ted M Ross, Christine Boyle, William D Martin & Anne S De Groot. (2013) Immunization with cross-conserved H1N1 influenza CD4+ T-cell epitopes lowers viral burden in HLA DR3 transgenic mice. Human Vaccines & Immunotherapeutics 9:10, pages 2060-2068.
Read now

Articles from other publishers (17)

Emily K. Makowski, Tiexin Wang, Jennifer M. Zupancic, Jie Huang, Lina Wu, John S. Schardt, Anne S. De Groot, Stephanie L. Elkins, William D. Martin & Peter M. Tessier. (2023) Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning. Nature Biomedical Engineering.
Crossref
Ramil R. Mintaev, Dina V. Glazkova, Olga V. Orlova, Elena V. Bogoslovskaya & German A. Shipulin. (2022) Development of a Universal Epitope-Based Influenza Vaccine and Evaluation of Its Effectiveness in Mice. Vaccines 10:4, pages 534.
Crossref
Nutan Mytle, Sonja Leyrer, Jon R. Inglefield, Andrea M. Harris, Thomas E. Hickey, Jacob Minang, Hang Lu, Zhidong Ma, Hanné Andersen, Nathan D. Grubaugh, Tina Guina, Mario H. Skiadopoulos & Michael J. Lacy. (2021) Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses. Viruses 13:9, pages 1708.
Crossref
Vinayaka Kotraiah, Timothy W. Phares, Frances E. Terry, Pooja Hindocha, Sarah E. Silk, Carolyn M. Nielsen, Leonard Moise, Kenneth D. Tucker, Rebecca Ashfield, William D. Martin, Anne S. De Groot, Simon J. Draper, Gabriel M. Gutierrez & Amy R. Noe. (2021) Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization. Frontiers in Immunology 12.
Crossref
Jan J. Gong, David J. Margolis & Dimitrios S. Monos. (2020) Predictive in silico binding algorithms reveal HLA specificities and autoallergen peptides associated with atopic dermatitis. Archives of Dermatological Research 312:9, pages 647-656.
Crossref
Lenny Moise, Andres H. Gutiérrez, Sundos Khan, Swan Tan, Matt Ardito, William D. Martin & Anne S. De Groot. (2020) New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand. Frontiers in Immunology 11.
Crossref
Anne S. De Groot, Leonard Moise, Frances Terry, Andres H. Gutierrez, Pooja Hindocha, Guilhem Richard, Daniel Fredric Hoft, Ted M. Ross, Amy R. Noe, Yoshimasa Takahashi, Vinayaka Kotraiah, Sarah E. Silk, Carolyn M. Nielsen, Angela M. Minassian, Rebecca Ashfield, Matt Ardito, Simon J. Draper & William D. Martin. (2020) Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools. Frontiers in Immunology 11.
Crossref
Christopher S. Eickhoff, Frances E. Terry, Linda Peng, Krystal A. Meza, Isaac G. Sakala, Daniel Van Aartsen, Leonard Moise, William D. Martin, Jill Schriewer, R. Mark Buller, Anne S. De Groot & Daniel F. Hoft. (2019) Highly conserved influenza T cell epitopes induce broadly protective immunity. Vaccine 37:36, pages 5371-5381.
Crossref
Anja Scholzen, Guilhem Richard, Leonard Moise, Laurie A. Baeten, Patrick M. Reeves, William D. Martin, Timothy A. Brauns, Christine M. Boyle, Susan Raju Paul, Richard Bucala, Richard A. Bowen, Anja Garritsen, Anne S. De Groot, Ann E. Sluder & Mark C. Poznansky. (2019) Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine. Frontiers in Immunology 10.
Crossref
Xianqiang Ping, Weibin Hu, Rui Xiong, Xi Zhang, Zheng Teng, Minyi Ding, Li Li, Chong Chang & Ke Xu. (2018) Generation of a broadly reactive influenza H1 antigen using a consensus HA sequence. Vaccine 36:32, pages 4837-4845.
Crossref
Yamato Wada, Arnone Nithichanon, Eri Nobusawa, Leonard Moise, William D. Martin, Norio Yamamoto, Kazutaka Terahara, Haruhisa Hagiwara, Takato Odagiri, Masato Tashiro, Ganjana Lertmemongkolchai, Haruko Takeyama, Anne S. De Groot, Manabu Ato & Yoshimasa Takahashi. (2017) A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines. Scientific Reports 7:1.
Crossref
Andres H. Gutiérrez, Crystal Loving, Leonard Moise, Frances E. Terry, Susan L. Brockmeier, Holly R. Hughes, William D. Martin & Anne S. De Groot. (2016) In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model. PLOS ONE 11:7, pages e0159237.
Crossref
John Jay Treanor. (2015) Prospects for Broadly Protective Influenza Vaccines. American Journal of Preventive Medicine 49:6, pages S355-S363.
Crossref
John Jay Treanor. (2015) Prospects for broadly protective influenza vaccines. Vaccine 33, pages D39-D45.
Crossref
Lynda Coughlan & Teresa Lambe. (2015) Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges. Vaccines 3:2, pages 293-319.
Crossref
Yo Jang & Baik Seong. (2014) Options and Obstacles for Designing a Universal Influenza Vaccine. Viruses 6:8, pages 3159-3180.
Crossref
Andrea Romero-Maldonado, Jorge A. Salazar-González & Sergio Rosales-Mendoza. 2014. Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases. Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases 129 139 .

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.