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Research Paper

Comparison of safety and immunogenicity of purified chick embryo cell vaccine using Zagreb and Essen regimens in patients with category II exposure in China

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Pages 1645-1649 | Received 21 Nov 2013, Accepted 03 Mar 2014, Published online: 14 Mar 2014

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Waqar Ali, Mohammad Ismail Tajik, Iftikhar Ali, Alia Gul & Jehan Zeb Khan. (2023) Safety of purified Vero cell rabies vaccine manufactured in Pakistan: a comparative analysis of intradermal and intramuscular routes. Current Medical Research and Opinion 39:5, pages 789-796.
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Xiaoyuan Huang, Jing Liang, Lili Huang, Xuanxuan Nian, Wei Chen, Jiayou Zhang, Xiao Xu, Xuan Lin, Yue Wang, Jinrong Shi, Lanxin Jia, Qingliang Li, Qianxi Wang, Kai Duan, Xinguo Li, Yaqi Ji, Feixia Peng, Wei Zhang, Zhiqiang Xie, Yanxia Wang & Xiaoming Yang. (2023) Safety and immunogenicity of rabies vaccine (PVRV-WIBP) in healthy Chinese aged 10–50 years old: Randomized, blinded, parallel controlled phase III clinical study. Human Vaccines & Immunotherapeutics 19:1.
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Lei Zhang, Shichun Huang, Li Cai, Zhenggang Zhu, Jian Chen, Sha Lu, Zerong Zhu, Man Zhang, Yuan Fang & Quan Hu. (2021) Safety, immunogenicity of lyophilized purified vero cell cultured rabies vaccine administered in Zagreb and Essen regimen in post-exposure subjects: A post-marketing, parallel control clinical trial. Human Vaccines & Immunotherapeutics 17:8, pages 2547-2553.
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Heng Shen, Zhao Wang, Beifang Yang, Kun Cai, Changjun Jiang, Ronghua Xie, Haitao Xiao, Qunhui Ren, Zhengxu Qi, Jinghui Li, Qiong Li, Jianjun Ye & Faxian Zhan. (2021) Immunogenicity and safety of purified vero cell-cultured rabies vaccine under Zagreb 2-1-1 or 5-dose Essen regimen in the healthy Chinese subjects: a randomized, double-blind, positive controlled phase 3 clinical trial. Human Vaccines & Immunotherapeutics 17:2, pages 351-357.
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Zhenggang Zhu, Shichun Huang, Sha Lu, Man Zhang, Shengli Meng, Quan Hu & Yuan Fang. (2020) Severe multiple rabid dog bite injuries in a child in central China: Continuous 10-year observation and analysis on this case. Human Vaccines & Immunotherapeutics 16:4, pages 904-906.
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Shichun Huang, Zhenggang Zhu, Li Cai, Zerong Zhu, Man Zhang, Quan Hu & Yuan Fang. (2019) Analysis on the risks of severe adverse events in rabies post-exposure prophylaxis and appropriate decision-making procedure. Human Vaccines & Immunotherapeutics 15:9, pages 2121-2125.
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Scott Preiss, Pornthep Chanthavanich, Lin H. Chen, Cinzia Marano, Philippe Buchy, Rosa van Hoorn, Marije Vonk Noordegraaf & Piyali Mukherjee. (2018) Post-exposure prophylaxis (PEP) for rabies with purified chick embryo cell vaccine: a systematic literature review and meta-analysis. Expert Review of Vaccines 17:6, pages 525-545.
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Nianmin Shi, Yibin Zhang, Huizhen Zheng, Zhenggang Zhu, Dingming Wang, Sihai Li, Yuhua Li, Liqing Yang, Junnan Zhang, Yunhua Bai, Qiang Lu, Zheng Zhang, Fengji Luo, Chun Yu & Li Li. (2017) Immunogenicity, safety and antibody persistence of a purified vero cell cultured rabies vaccine (Speeda) administered by the Zagreb regimen or Essen regimen in post-exposure subjects. Human Vaccines & Immunotherapeutics 13:6, pages 1338-1345.
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Jing Wang, FengJi Luo, ZiJian Feng, Li Li, YunHua Bai, Xing Ai, JianXin Ma, Zheng Zhang & NianMin Shi. (2017) Immunogenicity and safety of purified vero cell rabies vaccine (PVRV) produced by Liaoning Cheng Da Co. under Zagreb 2-1-1 or 5-dose Essen regimen in Chinese adults aged 50 and above. Human Vaccines & Immunotherapeutics 13:1, pages 144-150.
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Yuan Fang, Man-Qing Liu, Li Chen, Zheng-Gang Zhu, Ze-Rong Zhu & Quan Hu. (2016) Rabies post-exposure prophylaxis for a child with severe allergic reaction to rabies vaccine. Human Vaccines & Immunotherapeutics 12:7, pages 1802-1804.
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RongCheng Li, YanPing Li, ShuQing Wen, HuiChun Wen, Yi Nong, Zhaojun Mo, Fang Xie & Michele Pellegrini. (2015) Immunogenicity and safety of purified chick-embryo cell rabies vaccine under Zagreb 2-1-1 or 5-dose Essen regimen in Chinese children 6 to 17 years old and adults over 50 years: A randomized open-label study . Human Vaccines & Immunotherapeutics 11:2, pages 435-442.
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Jun Peng, Li Chen, Zheng-Gang Zhu, Ze-Rong Zhu, Quan Hu & Yuan Fang. (2014) Effect of Corticosteroids on RVNA production of a patient with acute disseminated encephalomyelitis following rabies vaccination as well as administration of HRIG. Human Vaccines & Immunotherapeutics 10:12, pages 3622-3626.
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Articles from other publishers (6)

Xiaohong Wu, Jia Li, Lei Zhou, Jianmin Chen, Zhongqiang Jin, Qingwei Meng, Jing Chai, Hongxia Gao, Yunpeng Wang, Danhua Zhao, Heng Wu, Jieran Yu, Nan Chen, Yanan Wang, Yuan Lin, Peifang Huang, Yuhua Li & Yuhui Zhang. (2023) A Randomized, Double-Blind, Controlled Phase III Clinical Trial to Evaluate the Immunogenicity and Safety of a Lyophilized Human Rabies Vaccine (Vero Cells) in Healthy Participants Aged 10–60 Years Following Essen and Zagreb Vaccination Procedures. Vaccines 11:8, pages 1311.
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Lei Wang, Jing Zhang, Shengli Meng, Lingrui Ge, Yuanyuan You, Qi Xu, Hongbo Wang, Jing Yang, Shuai Wang & Haofei Wu. (2022) Safety and immunogenicity of human rabies vaccine for the Chinese population after PEP: A systematic review and meta-analysis. Vaccine 40:32, pages 4371-4379.
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Ting Li, Xin Wang & Hongbin Cheng. (2020) Meta-analysis of immunogenicity and safety of human rabies vaccination under Zagreb and Essen regimens. Journal of Comparative Effectiveness Research 9:7, pages 459-468.
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Jun Peng, Sha Lu, Zhenggang Zhu, Man Zhang, Quan Hu & Yuan Fang. (2016) Safety comparison of four types of rabies vaccines in patients with WHO category II animal exposure. Medicine 95:47, pages e5049.
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Jiangping Ren, Linong Yao, Jimin Sun & Zhenyu Gong. (2015) Zagreb Regimen, an Abbreviated Intramuscular Schedule for Rabies Vaccination. Clinical and Vaccine Immunology 22:1, pages 1-5.
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Yuan Fang, Li Chen, Man-Qing Liu, Zheng-Gang Zhu, Ze-Rong Zhu & Quan Hu. (2014) Comparison of Safety and Immunogenicity of PVRV and PCECV Immunized in Patients with WHO Category II Animal Exposure: A Study Based on Different Age Groups. PLoS Neglected Tropical Diseases 8:12, pages e3412.
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