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Research Paper

Quantitative intravital two-photon excitation microscopy reveals absence of pulmonary vaso-occlusion in unchallenged Sickle Cell Disease mice

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Article: e29748 | Received 25 Apr 2014, Accepted 26 Jun 2014, Published online: 07 Jul 2014

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Ravi Vats, Zimming Li, Eun-Mi Ju, Rikesh K Dubey, Tomasz W Kaminski, Simon Watkins & Tirthadipa Pradhan-Sundd. (2022) Intravital imaging reveals inflammation as a dominant pathophysiology of age-related hepatovascular changes. American Journal of Physiology-Cell Physiology.
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Yoshikazu TsukasakiPeter T. Toth, Esmaeil Davoodi-BojdJalees Rehman & Asrar B. Malik. (2022) Quantitative Pulmonary Neutrophil Dynamics Using Computer-Vision Stabilized Intravital Imaging. American Journal of Respiratory Cell and Molecular Biology 66:1, pages 12-22.
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Ravi Vats, Tomasz W. Kaminski & Tirthadipa Pradhan‐Sundd. (2021) Intravital Imaging of Hepatic Blood Biliary Barrier in Live Mice. Current Protocols 1:10.
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Tomasz Brzoska, Tomasz W. Kaminski, Margaret F. Bennewitz & Prithu Sundd. (2020) Live Imaging of the Lung. Current Protocols in Cytometry 95:1.
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I. I. Dolgushin & E. A. Mezentseva. (2020) Neutrophil granulocytes: participation in homeostatic and reparative processes. Part I. Russian Journal of Infection and Immunity 10:4, pages 609-624.
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Tomasz Brzoska, Ravi Vats, Margaret F. Bennewitz, Egemen Tutuncuoglu, Simon C. Watkins, Margaret V. Ragni, Matthew D. Neal, Mark T. Gladwin & Prithu Sundd. (2020) Intravascular hemolysis triggers ADP-mediated generation of platelet-rich thrombi in precapillary pulmonary arterioles. JCI Insight 5:14.
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Ravi Vats, Egemen Tutuncuoglu, Tirthadipa Pradhan-Sundd, Jesus Tejero, Gray D. Shaw & Prithu Sundd. (2020) Tandem P-selectin glycoprotein ligand immunoglobulin prevents lung vaso-occlusion in sickle cell disease mice. Experimental Hematology 84, pages 1-6.e1.
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Margaret F. Bennewitz, Egemen TutuncuogluShweta GudapatiTomasz BrzoskaSimon C. WatkinsSatdarshan P. Monga, Tirthadipa Pradhan-Sundd & Prithu Sundd. (2020) P-selectin–deficient mice to study pathophysiology of sickle cell disease. Blood Advances 4:2, pages 266-273.
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Julien Stackowicz, Friederike Jönsson & Laurent L. Reber. (2020) Mouse Models and Tools for the in vivo Study of Neutrophils. Frontiers in Immunology 10.
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Ravi Vats, Tomasz Brzoska, Margaret F. Bennewitz, Maritza A. Jimenez, Tirthadipa Pradhan-Sundd, Egemen Tutuncuoglu, Jude Jonassaint, Edgar Gutierrez, Simon C. Watkins, Sruti Shiva, Melanie J. Scott, Adrian E. Morelli, Matthew D. Neal, Gregory J. Kato, Mark T. Gladwin & Prithu Sundd. (2020) Platelet Extracellular Vesicles Drive Inflammasome–IL-1β–Dependent Lung Injury in Sickle Cell Disease. American Journal of Respiratory and Critical Care Medicine 201:1, pages 33-46.
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Yixiang Deng, Dimitrios P. Papageorgiou, Hung-Yu Chang, Sabia Z. Abidi, Xuejin Li, Ming Dao & George Em Karniadakis. (2019) Quantifying Shear-Induced Deformation and Detachment of Individual Adherent Sickle Red Blood Cells. Biophysical Journal 116:2, pages 360-371.
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Tirthadipa Pradhan-Sundd, Ravi Vats, Jacquelyn O. Russell, Sucha Singh, Adeola Adebayo Michael, Laura Molina, Shelly Kakar, Pamela Cornuet, Minakshi Poddar, Simon C. Watkins, Kari N. Nejak-Bowen, Satdarshan P. Monga & Prithu Sundd. (2018) Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology 155:4, pages 1218-1232.e24.
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Clément Ricard, Erica D. Arroyo, Cynthia X. He, Carlos Portera-Cailliau, Gabriel Lepousez, Marco Canepari & Daniel Fiole. (2018) Two-photon probes for in vivo multicolor microscopy of the structure and signals of brain cells. Brain Structure and Function 223:7, pages 3011-3043.
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Tirthadipa Pradhan‐Sundd, Lili Zhou, Ravi Vats, An Jiang, Laura Molina, Sucha Singh, Minakshi Poddar, Jacquelyn Russell, Donna B Stolz, Michael Oertel, Udayan Apte, Simon Watkins, Sarangarajan Ranganathan, Kari N. Nejak‐Bowen, Prithu Sundd & Satdarshan Pal Monga. (2018) Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis. Hepatology 67:6, pages 2320-2337.
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Michael A. Washington, Stephen C. Balmert, Morgan V. Fedorchak, Steven R. Little, Simon C. Watkins & Tara Y. Meyer. (2018) Monomer sequence in PLGA microparticles: Effects on acidic microclimates and in vivo inflammatory response. Acta Biomaterialia 65, pages 259-271.
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Margaret F. Bennewitz, Maritza A. Jimenez, Ravi Vats, Egemen Tutuncuoglu, Jude Jonassaint, Gregory J. Kato, Mark T. Gladwin & Prithu Sundd. (2017) Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli. JCI Insight 2:1.
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Prithu Sundd & Margaret F. Bennewitz. 2017. Hematologic Abnormalities and Acute Lung Syndromes. Hematologic Abnormalities and Acute Lung Syndromes 19 45 .
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Bettina Stolp & Keira Melican. (2016) Microbial pathogenesis revealed by intravital microscopy: pros, cons and cautions. FEBS Letters 590:13, pages 2014-2026.
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Dipasri KonarMahesh DevarasettyDidem V. YildizAnthony AtalaSean V. Murphy. (2016) Lung-On-A-Chip Technologies for Disease Modeling and Drug Development. Biomedical Engineering and Computational Biology 7s1, pages BECB.S34252.
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