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Immunogenicity of different stressed IgG monoclonal antibody formulations in immune tolerant transgenic mice

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Pages 740-752 | Published online: 05 Sep 2012

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Jerome Egli, Stefan Heiler, Felix Weber, Guido Steiner, Timo Schwandt, Katharine Bray-French, Christian Klein, Sebastian Fenn, Gregor P. Lotz, Eugenia Opolka-Hoffmann, Thomas E. Kraft, Laetitia Petersen, Rebecca Moser, Jonathan DeGeer, Michel Siegel, Daniela Finke, Juliana Bessa & Antonio Iglesias. (2022) Enhanced immunogenic potential of cancer immunotherapy antibodies in human IgG1 transgenic mice. mAbs 14:1.
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Michael J. Knight, Léontine Floret, Nisha Patel, John O’Hara & Elizabeth Rodriguez. (2022) The impact of forced degradation conditions on mAb dimer formation and subsequent influence on aggregation propensity. mAbs 14:1.
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Marie R.G. Kopp, Adriana-Michelle Wolf Pérez, Marta Virginia Zucca, Umberto Capasso Palmiero, Brigitte Friedrichsen, Nikolai Lorenzen & Paolo Arosio. (2020) An accelerated surface-mediated stress assay of antibody instability for developability studies. mAbs 12:1.
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Elsa Bodier-Montagutelli, Alexie Mayor, Laurent Vecellio, Renaud Respaud & Nathalie Heuzé-Vourc’h. (2018) Designing inhaled protein therapeutics for topical lung delivery: what are the next steps?. Expert Opinion on Drug Delivery 15:8, pages 729-736.
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Karthik Pisupati, Alexander Benet, Yuwei Tian, Solomon Okbazghi, Jukyung Kang, Michael Ford, Sergei Saveliev, K. Ilker Sen, Eric Carlson, Thomas J. Tolbert, Brandon T. Ruotolo, Steven P. Schwendeman & Anna Schwendeman. (2017) Biosimilarity under stress: A forced degradation study of Remicade® and Remsima™. mAbs 9:7, pages 1197-1209.
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Christine P. Chan. (2016) Forced degradation studies: current trends and future perspectives for protein-based therapeutics. Expert Review of Proteomics 13:7, pages 651-658.
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Renaud Respaud, Laurent Vecellio, Patrice Diot & Nathalie Heuzé-Vourc’h. (2015) Nebulization as a delivery method for mAbs in respiratory diseases. Expert Opinion on Drug Delivery 12:6, pages 1027-1039.
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Audrey E Baker, Amber R Mantz & Mark L Chiu. (2014) Raman spectroscopy characterization of antibody phases in serum. mAbs 6:6, pages 1509-1517.
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