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mAbs Volume 6, 2014 - Issue 3
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A combinatorial mutagenesis approach for functional epitope mapping on phage-displayed target antigen

Application to antibodies against epidermal growth factor

Yanelys Cabrera Infante Systems Biology Department; Center of Molecular Immunology; La Habana, Cuba
,
Amaury Pupo Systems Biology Department; Center of Molecular Immunology; La Habana, Cuba
&
Gertrudis Rojas Systems Biology Department; Center of Molecular Immunology; La Habana, CubaCorrespondence[email protected]
Pages 637-648 | Received 27 Jan 2014, Accepted 21 Feb 2014, Published online: 03 Mar 2014

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Tiphanie Pruvost, Magali Mathieu, Steven Dubois, Bernard Maillère, Emmanuelle Vigne & Hervé Nozach. (2023) Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold. mAbs 15:1.
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Elisa María Castells Martínez, Ruben del Valle, Ernesto Carlos González, Antonio Melchor, Pedro Lucio Pérez, Idania González, Adriana Carr & Kalet León. (2017) An enzyme immunoassay for determining epidermal growth factor (EGF) in human serum samples using an ultramicroanalytical system. Journal of Immunoassay and Immunochemistry 38:2, pages 190-201.
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Gertrudis Rojas, Yaima Tundidor & Yanelys Cabrera Infante. (2014) High throughput functional epitope mapping: Revisiting phage display platform to scan target antigen surface. mAbs 6:6, pages 1368-1376.
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Articles from other publishers (13)

Gertrudis Rojas. (2022) Understanding and Modulating Antibody Fine Specificity: Lessons from Combinatorial Biology. Antibodies 11:3, pages 48.
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Xuelian Han, Zhuming Cai, Yulong Dai, He Huang, Xiangwen Cao, Yuan Wang, Yingying Fang, Gang Liu, Min Zhang, Yuhang Zhang, Binhui Yang, Wei Xue, Guangyu Zhao, Wanbo Tai & Min Li. (2022) Re-burying Artificially Exposed Surface of Viral Subunit Vaccines Through Oligomerization Enhances Vaccine Efficacy. Frontiers in Cellular and Infection Microbiology 12.
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Woochang Hwang, Winnie Lei, Nicholas M Katritsis, Méabh MacMahon, Kathryn Chapman & Namshik Han. (2021) Current and prospective computational approaches and challenges for developing COVID-19 vaccines. Advanced Drug Delivery Reviews 172, pages 249-274.
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Gertrudis Rojas, Tania Carmenate, Julio Felipe Santo-Tomás, Pedro A. Valiente, Marlies Becker, Annia Pérez-Riverón, Yaima Tundidor, Yaquelín Ortiz, Jorge Fernandez de Cossio-Diaz, Luis Graça, Stefan Dübel & Kalet León. (2019) Directed evolution of super-secreted variants from phage-displayed human Interleukin-2. Scientific Reports 9:1.
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Zhu Guo, Jason R. Wilson, Ian A. York & James Stevens. (2018) Biosensor-based epitope mapping of antibodies targeting the hemagglutinin and neuraminidase of influenza A virus. Journal of Immunological Methods 461, pages 23-29.
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Lucia Borszekova Pulzova. 2005. Encyclopedia of Life Sciences. Encyclopedia of Life Sciences 1 7 .
Heather H. Gustafson, Audrey Olshefsky, Meilyn Sylvestre, Drew L. Sellers & Suzie H. Pun. (2018) Current state of in vivo panning technologies: Designing specificity and affinity into the future of drug targeting. Advanced Drug Delivery Reviews 130, pages 39-49.
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Alberto Leyva, Hector Santana, Milagros Font, Barbara Pérez & Rodolfo Valdés. (2018) An ELISA for quantification of recombinant human EGF in production process samples, serum and urine. Biologicals 51, pages 12-17.
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Xueni Chen & Stephen C. Dreskin. (2017) Application of phage peptide display technology for the study of food allergen epitopes. Molecular Nutrition & Food Research 61:6, pages 1600568.
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Lanying Du, Wanbo Tai, Yang Yang, Guangyu Zhao, Qing Zhu, Shihui Sun, Chang Liu, Xinrong Tao, Chien-Te K. Tseng, Stanley Perlman, Shibo Jiang, Yusen Zhou & Fang Li. (2016) Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines. Nature Communications 7:1.
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Lenka Potocnakova, Mangesh Bhide & Lucia Borszekova Pulzova. (2016) An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction. Journal of Immunology Research 2016, pages 1-11.
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Tarek A. Ahmad, Amrou E. Eweida & Salah A. Sheweita. (2016) B-cell epitope mapping for the design of vaccines and effective diagnostics. Trials in Vaccinology 5, pages 71-83.
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Katarzyna Hodyra & Krystyna Dąbrowska. (2014) Molecular and Chemical Engineering of Bacteriophages for Potential Medical Applications. Archivum Immunologiae et Therapiae Experimentalis 63:2, pages 117-127.
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